2770-92-5

Basic information

• Product Name: 2-(1H-Indol-3-yl)-2-methyl-propionic acid
• Synonyms: 2-(1H-Indol-3-yl)-2-methyl-propionic acid;2-(1H-indol-3-yl)-2-Methylpropanoic acid
• CAS NO: 2770-92-5
• Molecular Formula: C12H13NO2
• Molecular Weight: 203
• Mol File: 2770-92-5.mol
• Article Data: 0

Chemical Properties

• Melting Point: 135 °C(Solv: chloroform (67-66-3); ligroine (8032-32-4))
• Boiling Point: 404.225 °C at 760 mmHg
• Flash Point: 198.268 °C
• Appearance: /
• Density: 1.245 g/cm³
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.04±0.30(Predicted)
• CAS DataBase Reference: 2-(1H-Indol-3-yl)-2-methyl-propionic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1H-Indol-3-yl)-2-methyl-propionic acid(2770-92-5)
• EPA Substance Registry System: 2-(1H-Indol-3-yl)-2-methyl-propionic acid(2770-92-5)

Safety Data

• Hazardous Substances Data: 2770-92-5(Hazardous Substances Data)

Usage

General Description

2-(1H-Indol-3-yl)-2-methyl-propionic acid, also known simply under the name Indometacin, is a synthetic compound that belongs to a class of organic compounds known as indoles. Its chemical structure consists of a 2-methyl-propionic acid that is bound to an indole at the 2-position. This distinct compound is popularly recognized as a potent nonsteroidal anti-inflammatory drug (NSAID) that is conventionally used for relieving pain, reducing fever, and decreasing inflammation. It operates by inhibiting the production of prostaglandins, which are substances responsible for producing inflammation and pain within the body.

Upstream product

• 120-72-9 indole 
• 67-64-1 acetone 

Downstream Products

• 15467-31-9 2-(1H-indol-3-yl)-2-methylpropane-1-amine