27703-15-7

Basic information

• Product Name: N,N-dimethyl-N'-(toluene-4-sulfonyl)-carbamimidoyl chloride
• Synonyms: N,N-dimethyl-N'-(toluene-4-sulfonyl)-carbamimidoyl chloride
• CAS NO: 27703-15-7
• Molecular Weight: 260.744
• Mol File: 27703-15-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N,N-dimethyl-N'-(toluene-4-sulfonyl)-carbamimidoyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: N,N-dimethyl-N'-(toluene-4-sulfonyl)-carbamimidoyl chloride(27703-15-7)
• EPA Substance Registry System: N,N-dimethyl-N'-(toluene-4-sulfonyl)-carbamimidoyl chloride(27703-15-7)

Safety Data

• Hazardous Substances Data: 27703-15-7(Hazardous Substances Data)

Upstream product

• 473-34-7 N,N-dichloro-p-toluenesulfonamide 
• 34656-65-0 Dimethyltrichloromethylamine 
• 33842-02-3 dichloromethylenedimethyliminium chloride 
• 70-55-3 toluene-4-sulfonamide 

Downstream Products

• 71715-39-4 N-(toluene-4-sulfonyl)-morpholine-4-carboximidic acid dimethylamide 
• 13839-37-7 N-<(Dimethylamino)hydrazinomethylen>-p-toluolsulfonamid 
• 13750-34-0 N--p-toluolsulfonamid 
• 84274-88-4 N--p-toluolsulfonamid 
• 84274-95-3 1-1,N¹-Dimethyl-N²-(p-tosyl)amidino>-5--1,2,3-triazol 
• 80608-56-6 N₁,N₁-Dimethyl-3-(N-methylanilino)-N₂-tosylpropiolamidin 

Relevant articles and documents

Iminium Salts in Quantitative Gas/Solid and Solid/Solid Reactions

Iminium salts that are highly susceptible to hydrolysis are quantitatively prepared and reacted in the solid state without solvents or liquid phases. Atomic force microscopy AFM helps in elucidating the mechanism of these still unusual gas-solid and solid-solid syntheses by recording surface topographies of reacting crystals of L-histidine (10) and triphenylverdazyl (15). Various imines add gaseous HCl or HBr to form stable iminium halides (1, 3, 4, 5, 11) even if frozen liquids of very weak heterocyclic bases are treated at low temperatures. Another way for quantitative yields of iminium salt hydrates (6) starts with solid primary ammonium halides and gaseous acetone. o-Phenylenediamines (7) give quantitatively 1,5-benzodiazepines (9) by solid state cyclization of bis-iminium salt intermediates (8). Crystalline nitroxyls (12) and triphenylverdazyl (15) undergo stoichiometric one-electron transfer with gaseous NO2 or XeF2 to give nitrosonium (14) and azonium salts (17). The solid state chlorination of tetramethylthiuramdisulfide (18) or dimethylthiocarbamoylchloride (20) yields phosgene dimethyliminiumchloride (Viehe salt 21) in quantitative yield. Solid Viehe salt is quantitatively treated with gaseous Cl2 to give the trichloride 19 and solid SbCl5 or PCl5 to produce the hexachloroantimoniates (22), -phosphates (23). Solid brenzcatechol (24), mercaptobenzimidazole (27), p-nitroaniline (30), N-methylbenzothiazolone-2-hydrazone (34) and acetophenone (41) are treated with 21 to give the corresponding chloroiminium salts (25, 28, 31, 35, 43). p-Toluenesulfonamide (37) and 22 give the chloroiminium salt 38.These quantitative solid-solid reactions are most easily run in ball mills with cooling device. The "waste-free" techniques achieve exclusion of moisture in an elegant way. The preparative use of the versatile products with nucleophiles is indicated. The three-step solid-state mechanisms are discussed.