27782-63-4 Usage
Description
Santin, also known as a trimethoxyflavone, is a type of flavone that is substituted by methoxy groups at positions 3, 6, and 4', and hydroxy groups at positions 5 and 7 respectively. It is a naturally occurring compound with potential applications in various industries due to its unique chemical structure and properties.
Uses
Used in Pharmaceutical Industry:
Santin is used as a pharmaceutical compound for its potential therapeutic effects. Its unique structure allows it to interact with various biological targets, making it a promising candidate for the development of new drugs.
Used in Cosmetic Industry:
Santin is used as an active ingredient in the cosmetic industry for its potential benefits to skin health. Its antioxidant and anti-inflammatory properties may contribute to improved skin condition and protection against environmental stressors.
Used in Food Industry:
Santin is used as a natural additive in the food industry for its potential to enhance the flavor and aroma of various products. Its unique chemical structure may also provide preservative or antioxidant properties, extending the shelf life and improving the quality of the final product.
Used in Agricultural Industry:
Santin is used as a natural pesticide or fungicide in the agricultural industry. Its antimicrobial properties may help protect crops from various diseases and pests, promoting healthier growth and increased yield.
Used in Research and Development:
Santin is used as a research compound for the development of new materials and technologies. Its unique chemical properties may be harnessed to create innovative products and applications in various fields, including materials science, nanotechnology, and biotechnology.
Check Digit Verification of cas no
The CAS Registry Mumber 27782-63-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,7,8 and 2 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 27782-63:
(7*2)+(6*7)+(5*7)+(4*8)+(3*2)+(2*6)+(1*3)=144
144 % 10 = 4
So 27782-63-4 is a valid CAS Registry Number.
InChI:InChI=1/C18H16O7/c1-22-10-6-4-9(5-7-10)16-18(24-3)15(21)13-12(25-16)8-11(19)17(23-2)14(13)20/h4-8,19-20H,1-3H3
27782-63-4Relevant articles and documents
In vitro biological evaluation and molecular docking studies of natural and semisynthetic flavones from Gardenia oudiepe (Rubiaceae) as tyrosinase inhibitors
Santi,Bouzidi,Gorod,Puiatti,Michel,Grougnet,Ortega
, p. 241 - 245 (2018/11/06)
Hyperpigmentation disorders are difficult to treat without causing permanent depigmentation or irritation. The most effective hypopigmenting agents are tyrosinase inhibitors, however some of those currently used have shown serious side effects. As several classes of flavonoids have already demonstrated ability to inhibit tyrosinase, a library of natural polymethoxyflavones isolated (1–7) from the bud exudate of Gardenia oudiepe and semi-synthetic derivatives (8,9) were evaluated. IC50 of the most active compounds were in the micromolar range. The strongest inhibitors 1, 2 and 3 all shared a 3′,4′-dimethoxy-5′-hydroxy trisubstituted B ring. These SAR conclusions were confirmed by molecular docking studies. The mode of interaction with the enzyme was elucidated, and important interactions between the most active compounds and catalytic residues of tyrosinase were observed. All of these data provided a library of compounds as potential leaders for the design of new depigmenting agents and formulations.
