27825-21-4 Usage
Description
Methyl 3-chloro-2-pyrazinecarboxylate, with the CAS number 27825-21-4, is an organic compound that serves as a valuable intermediate in the synthesis of various chemical products. It is characterized by its unique molecular structure, which includes a pyrazine ring with a chloro substituent and a methyl ester group. Methyl 3-chloro-2-pyrazinecarboxylate is known for its reactivity and versatility in chemical reactions, making it a significant building block in the development of new molecules with potential applications in different industries.
Uses
Used in Organic Synthesis:
Methyl 3-chloro-2-pyrazinecarboxylate is used as a synthetic intermediate for the production of various chemical compounds. Its unique structure allows it to participate in a wide range of chemical reactions, such as nucleophilic substitution, electrophilic aromatic substitution, and condensation reactions. This versatility makes it a valuable asset in the synthesis of pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Methyl 3-chloro-2-pyrazinecarboxylate is used as a key building block for the development of new drugs. Its reactivity and structural diversity enable the creation of novel molecules with potential therapeutic applications. These molecules may target various diseases and conditions, including cancer, inflammation, and infectious diseases.
Used in Agrochemical Industry:
Methyl 3-chloro-2-pyrazinecarboxylate is also utilized in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its unique chemical properties allow for the development of innovative compounds with improved efficacy, selectivity, and environmental compatibility.
Used in Flavor and Fragrance Industry:
In the flavor and fragrance industry, Methyl 3-chloro-2-pyrazinecarboxylate can be used as a starting material for the synthesis of novel aroma chemicals. These compounds can be used to create unique and complex scents for use in perfumes, cosmetics, and other consumer products.
Used in Dye and Pigment Industry:
Methyl 3-chloro-2-pyrazinecarboxylate can also be employed in the synthesis of new dyes and pigments for various applications, such as textiles, plastics, and printing inks. Its unique molecular structure can contribute to the development of dyes with improved color strength, stability, and fastness properties.
Check Digit Verification of cas no
The CAS Registry Mumber 27825-21-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,7,8,2 and 5 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 27825-21:
(7*2)+(6*7)+(5*8)+(4*2)+(3*5)+(2*2)+(1*1)=124
124 % 10 = 4
So 27825-21-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H5ClN2O2/c1-11-6(10)4-5(7)9-3-2-8-4/h2-3H,1H3
27825-21-4Relevant articles and documents
Derivatives of pyrazinecarboxylic acid: 1H, 13C and 15N NMR spectroscopic investigations
Holzer, Wolfgang,Eller, Gernot A.,Datterl, Barbara,Habicht, Daniela
scheme or table, p. 617 - 624 (2010/07/05)
NMR spectroscopic studies are undertaken with derivatives of 2-pyrazinecarboxylic acid. Complete and unambiguous assignment of chemical shifts (1H, 13C, 15N) and coupling constants (1H,1H; 13C,1H; 15N,1H) is achieved by combined application of various 1D and 2D NMR spectroscopic techniques. Unequivocal mapping of13C,1H spin coupling constants is accomplished by 2D (S,J) long-range INEPT spectra with selective excitation. Phenomena such as the tautomerism of 3-hydroxy-2-pyrazinecarboxylic acid are discussed.
Studies on Pyrazines. 29. High Regioselective Synthesis of Chloropyrazines from 3-Substituted Pyrazine 1-Oxides
Sato, Nobuhiro,Fujii, Megumi
, p. 1177 - 1180 (2007/10/02)
Reaction of 3-methoxy- or 3-chloropyrazine 1-oxides with refluxing phosphoryl chloride in the presence of amine led to a high regioselective formation of 3-substituted 2-chloropyrazines.In contrast, the use of chloroacetyl chloride instead of phosphoryl chloride enabled different regioselectivity to yield 6-substituted 2-chloropyrazines, particularly 3-methoxycarbonylpyrazine 1-oxide was almost exclusively converted into methyl 6-chloropyrazinecarboxylate under conditions without the amine.
