27888-23-9Relevant articles and documents
Synthesis and biological evaluation of bifendate derivatives bearing acrylamide moiety as novel antioxidant agents
Gu, Xiaoke,Jiang, Yanfei,Chen, Jing,Zhang, Yinpeng,Guan, Mingyu,Li, Xin,Zhou, Qingqing,Lu, Qian,Qiu, Jingying,Yin, Xiaoxing
, p. 59 - 69 (2018/11/21)
Oxidative stress plays a significant role in the pathogenesis of various human diseases. In this study, a series of bifendate derivatives bearing acrylamide moiety were synthesized and evaluated as anti-oxidant agents. Biological evaluation indicated that
α-Isocyanatoacrylonitriles from alkylidene- or arylidenecyanoacetic acids; synthesis and reactions
Jaafar,Francis,Danion-Bougot,Danion
, p. 56 - 60 (2007/10/02)
The Curtius reaction converts alkylidene- or arylidenecyanoacetic acids to α-isocyanatoacrylonitriles in a stereospecific way. These versatile intermediates allow an easy access to arylacetic acids and various amino acid derivatives, as well as β-lactams or 2-azabutadienes.