27913-96-8

Basic information

• Product Name: 4-(1,1-DIOXOTHIOMORPHOLINO)BENZALDEHYDE
• Synonyms: 4-(4-FORMYLPHENYL)THIOMORPHOLINE 1,1-DIOXIDE;4-(1,1-DIOXOTHIOMORPHOLINO)BENZALDEHYDE;4-(1,1-Dioxido-4-thiomorpholinyl)benzaldehyde;4-(1,1-dioxo-1,4-thiazinan-4-yl)benzaldehyde
• CAS NO: 27913-96-8
• Molecular Formula: C₁₁H₁₃NO₃S
• Molecular Weight: 239.29
• Mol File: 27913-96-8.mol
• Article Data: 3

Chemical Properties

• Melting Point: 183.0 to 187.0 °C
• Boiling Point: 518.056°C at 760 mmHg
• Flash Point: 267.111°C
• Appearance: /
• Density: 1.33g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.592
• PKA: 0.42±0.40(Predicted)
• CAS DataBase Reference: 4-(1,1-DIOXOTHIOMORPHOLINO)BENZALDEHYDE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1,1-DIOXOTHIOMORPHOLINO)BENZALDEHYDE(27913-96-8)
• EPA Substance Registry System: 4-(1,1-DIOXOTHIOMORPHOLINO)BENZALDEHYDE(27913-96-8)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• Hazardous Substances Data: 27913-96-8(Hazardous Substances Data)

Usage

General Description

4-(1,1-Dioxothiomorpholino)benzaldehyde is a chemical compound with the molecular formula C11H11NO3S. It is a benzaldehyde derivative containing a thiomorpholine ring and a dioxo group. 4-(1,1-DIOXOTHIOMORPHOLINO)BENZALDEHYDE is often used as an intermediate in the synthesis of various pharmaceuticals and organic compounds. It has a variety of potential applications in the field of medicinal chemistry and drug development. The presence of the dioxo and thiomorpholino groups in its structure make it an important building block for the synthesis of biologically active molecules. Additionally, it has potential use in chemical research and development due to its unique structure and reactivity. Overall, 4-(1,1-Dioxothiomorpholino)benzaldehyde has significant value as a versatile and important chemical intermediate.

InChI:InChI=1/C11H13NO3S/c13-9-10-1-3-11(4-2-10)12-5-7-16(14,15)8-6-12/h1-4,9H,5-8H2

Upstream product

• 17688-68-5 4-Phenyltetrahydro-1,4-thiazine 1,1-dioxide 
• 68-12-2 N,N-dimethyl-formamide 
• 39093-93-1 thiomorpholine 1,1-dioxide 
• 459-57-4 4-fluorobenzaldehyde 

Downstream Products

• 942950-88-1 2-(4-(6-Chloro-2-(4-(1,1-dioxothiomorpholino)phenyl)-3H-imidazo[4,5-b]pyridin-7-yl)piperazin-1-yl)-N-(thiazol-2-yl)acetamide 
• 1207549-71-0 C₂₂H₂₆BrN₃O₆S 

Relevant articles and documents

N-SUBSTITUTED-3,4-(FUSED 5-RING)-5-PHENYL-PYRROLIDINE-2-ONE COMPOUNDS AS INHIBITORS OF ISOQC AND/OR QC ENZYME

The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain N-substituted-3,4-(fused 5-ring)-5-phenyl-pyrrolidin-2-one compounds (also referred to herein as "FRPPO compounds"), that, inter alia, inhibit glutaminyl-peptide cyclotransferase-like (isoQC) enzyme and/or glutaminyl-peptide cyclotransferase (QC) enzyme (e.g., inhibit or reduce or block the activity or function of isoQC and/or QC enzyme). The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit isoQC and/or QC enzyme; to treat disorders that are ameliorated by the inhibition of isoQC and/or QC enzyme; to treat cancer, atherosclerosis, fibrotic diseases, infectious diseases, Alzheimer's disease, etc.

Copolymerizable methine and anthraquinone compounds and articles containing them

This invention relates to polymerizable ultraviolet light absorbers and yellow colorants and their use in ophthalmic lenses. In particular, this invention relates to polymerizable ultraviolet light absorbing methine compounds and yellow compounds of the methine and anthraquinone classes that block ultraviolet light and/or violet-blue light transmission through ophthalmic lenses.