28036-31-9Relevant articles and documents
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents
Chaouni-Benabdallah, Aziz,Galtier, Christophe,Allouchi, Hassan,Kherbeche, Abdelak,Chavignon, Olivier,Teulade, Jean-Claude,Witvrouw, Myriam,Pannecouque, Christophe,Snoeck, Robert,Andrei, Graciela,Balzarini, Jan,De Clercq, Erik,Fauvelle, Florence,Enguehard, Cecile,Gueiffier, Alain
, p. 1631 - 1635 (2001)
This work reports the synthesis and the antiviral activities of 3-benzamido, 3-phenylureido and 3-phenylthioureido derivatives in the imidazo[1,2-a]pyridine series. The structure was proven by NMR spectroscopy. The synthesized compounds were evaluated against a large number of viruses. The 3-phenylthioureido derivative 7 showed moderate activity against human cytomegalovirus (HCMV) in vitro. The crystallographic data for 8 are also reported and explain the absence of activity against human immunodeficiency virus (HIV).
Studies on Heterocyclic Compounds: Part I. Synthesis of 3-amino-2-sub-Imidazo(1,2-a)-pyridines
Astik, R. R.,Thaker, K. A.
, p. 1013 - 1014 (2007/10/02)
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