34165-09-8Relevant articles and documents
New pyrazole derivatives as CRAC channel modulators
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Paragraph 0099, (2015/03/28)
The present invention relates to compounds of formula (I) which are inhibitors of CRAC channel activity. This invention also relates to pharmaceutical compositions containing them, process for their preparation and their use in therapy.
3-Benzamido, ureido and thioureidoimidazo[1,2-a]pyridine derivatives as potential antiviral agents
Chaouni-Benabdallah, Aziz,Galtier, Christophe,Allouchi, Hassan,Kherbeche, Abdelak,Chavignon, Olivier,Teulade, Jean-Claude,Witvrouw, Myriam,Pannecouque, Christophe,Snoeck, Robert,Andrei, Graciela,Balzarini, Jan,De Clercq, Erik,Fauvelle, Florence,Enguehard, Cecile,Gueiffier, Alain
, p. 1631 - 1635 (2007/10/03)
This work reports the synthesis and the antiviral activities of 3-benzamido, 3-phenylureido and 3-phenylthioureido derivatives in the imidazo[1,2-a]pyridine series. The structure was proven by NMR spectroscopy. The synthesized compounds were evaluated against a large number of viruses. The 3-phenylthioureido derivative 7 showed moderate activity against human cytomegalovirus (HCMV) in vitro. The crystallographic data for 8 are also reported and explain the absence of activity against human immunodeficiency virus (HIV).