28180-92-9 Usage
Description
N-Boc-Cephalexin, also known as Protected Cephalexin (C256800), is a semi-synthetic cephalosporin antibiotic derived from Cephalexin. It is characterized by its light yellow solid appearance and is widely recognized for its antimicrobial properties. The N-Boc group in its structure serves as a protecting agent, which is crucial for its stability and reactivity in various chemical and pharmaceutical processes.
Uses
Used in Pharmaceutical Industry:
N-Boc-Cephalexin is used as an intermediate in the synthesis of various cephalosporin antibiotics for the treatment of bacterial infections. Its role as a protected form of Cephalexin allows for the development of new and improved antibiotics with enhanced properties, such as increased stability, better bioavailability, and reduced side effects.
Used in Research and Development:
In the field of research and development, N-Boc-Cephalexin is utilized as a key compound for studying the structure-activity relationships of cephalosporin antibiotics. This helps scientists understand the molecular mechanisms underlying their antimicrobial action and design more effective drugs to combat resistant bacterial strains.
Used in Chemical Synthesis:
N-Boc-Cephalexin is also employed as a starting material or building block in the chemical synthesis of various complex organic molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its unique structure and reactivity make it a valuable asset in the synthesis of novel compounds with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 28180-92-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,1,8 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 28180-92:
(7*2)+(6*8)+(5*1)+(4*8)+(3*0)+(2*9)+(1*2)=119
119 % 10 = 9
So 28180-92-9 is a valid CAS Registry Number.
28180-92-9Relevant articles and documents
Synthesis and biochemical evaluation of cephalosporin analogues equipped with chemical tethers
Duhme-Klair, Anne-Kathrin,Gyulev, Ivan,Herman, Reyme,Krauss, Thomas F.,Miller, Lisa M.,Thomas, Gavin H.
, p. 36485 - 36494 (2020/10/28)
Molecular probes typically require structural modifications to allow for the immobilisation or bioconjugation with a desired substrate but the effects of these changes are often not evaluated. Here, we set out to determine the effects of attaching functio
Synthesis of potential impurities of cefalexin and cefradine
Hendrix,Roets,Bervoets,Thomas,Pijcke,Busson,Janssen,Hoogmartens
, p. 215 - 219 (2007/10/02)
The synthesis of some impurities of the cephalosporin antibiotics cefalexin and cefradine is described. These impurities which may be present in commercial samples are formed during the semi-synthetic preparation of these antibiotics or upon their degradation. The preparation of these compounds enables the validation of selective quantitative analytical methods, such as column liquid chromatography and thin layer chromatography.
