28288-50-8Relevant articles and documents
Benzoyl cyanide: A mild and efficient reagent for benzoylation of nucleosides
Prasad, Ashok K.,Kumar, Vineet,Maity, Jyotirmoy,Wang, Zhiwei,Ravikumar, Vasulinga T.,Sanghvi, Yogesh S.,Parmar, Virinder S.
, p. 935 - 945 (2007/10/03)
Efficient benzoylation of various nucleosides has been accomplished in pyridine with a catalytic amount of DMAP and benzoyl cyanide under mild conditions.
Incorporation Of 6-Thioguanosine Into Oligoribonucleotides
Adams, Chris J.,Murray, James B.,Farrow, Mark A.,Arnold, John R. P.,Stockley, Peter G.
, p. 5421 - 5424 (2007/10/02)
The preparation of N2-benzoyl-S6-cyanoethyl-6-thioguanosine and its incorporation into oligoribonucleotides, using standard phosphoramidite methods, is described. 6-Thioguanosine has been incorporated into the three guanosine sites of the central core of the hammerhead ribozyme resulting in 2- to 9-fold reductions in catalytic activity.
SYNTHESIS OF O6-p-NITROPHENYLETHYL GUANOSINE AND 2'-DEOXYGUANOSINE DERIVATIVES
Trichtinger, Thomas,Charubala, Ramamurthy,Pfleiderer, Wolfgang
, p. 711 - 714 (2007/10/02)
The p-nitrophenylethyl group is introduced into the O6-position of 2'-deoxyguanosine and guanosine via the Mitsunobu-reaction to yield valuable building blocks for oligonucleotide syntheses.