28291-63-6 Usage
Description
5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one is a chemical compound belonging to the dibenzazepine class. It is characterized by its unique molecular structure, which features a fused benzene ring system with an additional acetyl group at the 5-position. 5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one has potential applications in various fields due to its distinct chemical properties and interactions with other molecules.
Uses
Used in Pharmaceutical Industry:
5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one is used as an impurity in the production of Oxcarbazepine (O869250), an anticonvulsant medication. It plays a crucial role in ensuring the quality, safety, and efficacy of the final drug product by serving as a reference for the identification, testing, and quantification of impurities during the manufacturing process.
Used in Research and Development:
In the field of research and development, 5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one is used as a reference compound for the study of its chemical properties, interactions with other molecules, and potential applications in drug discovery. 5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one can be utilized to investigate its binding affinity to various biological targets, which may lead to the development of new therapeutic agents.
Used in Quality Control:
5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one is used as a reference material in the quality control of pharmaceutical products, particularly those containing Oxcarbazepine. It helps in the development and validation of analytical methods for the detection and quantification of impurities, ensuring the compliance of the drug product with regulatory standards.
Used in Metabolite Studies:
As a metabolite of Eslicarbazepine acetate (BIA 2-093), a novel central nervous system drug, 5-Acetyl-5H-dibenzo[b,f]azepin-10(11H)-one is used in the study of the drug's metabolism and pharmacokinetics. Understanding the metabolic pathways and the role of this metabolite can provide valuable insights into the drug's safety, efficacy, and potential side effects.
Check Digit Verification of cas no
The CAS Registry Mumber 28291-63-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,2,9 and 1 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 28291-63:
(7*2)+(6*8)+(5*2)+(4*9)+(3*1)+(2*6)+(1*3)=126
126 % 10 = 6
So 28291-63-6 is a valid CAS Registry Number.
28291-63-6Relevant articles and documents
ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME
-
, (2016/10/09)
The present invention relates to a novel compound represented by chemical formula 1, and an organic electroluminescent device comprising the same. The compound according to the present invention can improve light-emitting efficiency, driving voltage, and lifespan of the organic electroluminescent device by being used in an organic layer of the organic electroluminescent device.COPYRIGHT KIPO 2016
New synthesis of 10-alkoxy-5-H-dibenz[b,f]azepines
Haasz,Galamb
, p. 683 - 687 (2007/10/02)
The reaction of 5-acetyl-5H-dibenz[b,f]azepines with sodium-hypochlorite led to the 5-acetyl-10,11-epoxy-10,11-dihydro-5H-dibenz[b,f]azepine (1). The lithium iodide induced rearrangement of 1 gave the keton 2 which was reacted with trialkyl-orthoformates leading to the vinyl ethers 3a,b.
