2833-28-5

Basic information

• Product Name: 2-Pentenoic acid, 4-oxo-, (2E)-
• CAS NO: 2833-28-5
• Molecular Formula: C5H6O3
• Molecular Weight: 114.101
• Mol File: 2833-28-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-Pentenoic acid, 4-oxo-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 4-oxo-, (2E)-(2833-28-5)
• EPA Substance Registry System: 2-Pentenoic acid, 4-oxo-, (2E)-(2833-28-5)

Safety Data

• Hazardous Substances Data: 2833-28-5(Hazardous Substances Data)

Upstream product

• 14300-71-1 5-hydroxy-5-methyl-2(5H)-furanone 
• 100-52-7 benzaldehyde 
• 454-89-7 3-Trifluoromethylbenzaldehyde 
• 587-04-2 m-Chlorobenzaldehyde 
• 552-89-6 2-nitro-benzaldehyde 
• 534-22-5 2-methylfuran 
• 555-16-8 4-nitrobenzaldehdye 
• 99-61-6 3-nitro-benzaldehyde 
• 862015-59-6 γ-ethyl-γ-hydroxybutenolide 
• 2833-24-1 methyl (E)-4-oxo-2-pentenoate 

Downstream Products

• 169170-51-8 (E)-N-benzyl-4-oxopent-2-enamide 
• 129435-81-0 (E)-N-phenyl 4-oxopent-2-enamide 
• 102370-01-4 (+/-)-trans-6-acetyl-cyclohex-3-enecarboxylic acid 
• 108843-23-8 (+/-)-6t-acetyl-3-(4-methoxy-phenyl)-cyclohex-3-ene-r-carboxylic acid 
• 108840-35-3 (+/-)-6t-acetyl-4-(4-methoxy-phenyl)-cyclohex-3-ene-r-carboxylic acid 
• 497830-82-7 (E)-(S)-4-[Benzyl-((E)-4-oxo-pent-2-enoyl)-amino]-hex-2-enedioic acid 6-benzyl ester 1-ethyl ester 
• 497830-80-5 4-[benzyl-(4-oxo-pent-2-enoyl)-amino]-5-methylhex-2-enoic acid ethyl ester 
• 459833-02-4 4-[benzyl-(4-oxo-pent-2-enoyl)-amino]-5-phenyl-pent-2-enoic acid ethyl ester 

Relevant articles and documents

Acid-mediated coupling of γ-hydroxybutenolides and aldehydes: Synthesis of a new class of spirocyclic ketal-lactones

In the presence of trimethylsilyl trifluoromethanesulfonate (TMSOTf), γ-methyl-γ-hydroxybutenolide reacts with aromatic aldehydes to generate a new class of stereochemically rich spirocyclic ketal-lactones in good yields and with excellent stereoselectivities. We believe that this process takes place through the in situ generation of protoanemonin followed by a Prins reaction. Herein, we describe this discovery, along with substrate scope and preliminary mechanistic studies.

Assessment of the Active-Site Requirements of 5-Aminolaevulinic Acid Dehydratase: Evaluation of Substrate and Product Analogues as Competitive Inhibitors

The enzyme 5-aminolaevulinic acid dehydratase (ALAD) is resonsible for the synthesis of porphobilinogen (PBG) from two molecules of 5-aminolaevulinic acid (ALA).Porphobilinogen is an important committed intermediate in the biosynthesis of tetrapyrroles.Th