459833-02-4

Basic information

• Product Name: 2-Pentenoic acid, 4-[[(2E)-1,4-dioxo-2-pentenyl](phenylmethyl)amino]-5-phenyl-, ethyl ester, (2E,4S)-
• CAS NO: 459833-02-4
• Molecular Formula: C25H27NO4
• Molecular Weight: 405.494
• Mol File: 459833-02-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-Pentenoic acid, 4-[[(2E)-1,4-dioxo-2-pentenyl](phenylmethyl)amino]-5-phenyl-, ethyl ester, (2E,4S)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentenoic acid, 4-[[(2E)-1,4-dioxo-2-pentenyl](phenylmethyl)amino]-5-phenyl-, ethyl ester, (2E,4S)-(459833-02-4)
• EPA Substance Registry System: 2-Pentenoic acid, 4-[[(2E)-1,4-dioxo-2-pentenyl](phenylmethyl)amino]-5-phenyl-, ethyl ester, (2E,4S)-(459833-02-4)

Safety Data

• Hazardous Substances Data: 459833-02-4(Hazardous Substances Data)

Upstream product

• 4743-82-2 4-oxo-2-pentenoic acid 
• 244033-83-8 (4S)-4-N-benzylamino-5-phenyl-2-trans-pentenoic acid, ethyl ester 
• 2833-28-5 trans-4-oxo-2-pentenoic acid 
• 124818-94-6 ethyl (2E,4S)-4-[(tert-butoxycarbonyl)amino]-5-phenylpent-2-enoate 
• 244033-75-8 (S)-(+)-trans-5-phenyl-4-amino-2-pentenoic acid ethyl ester 
• 87694-53-9 Boc-Phe-OH N,O-dimethyl hydroxamate 
• 13734-34-4 N-tert-butoxycarbonyl-L-phenylalanine 
• 72155-45-4 Boc-L-phenylalaninal 

Downstream Products

• 459832-87-2 (3S,3aR,4S,7aR)-2,3-dibenzyl-6-methyl-1-oxo-1,2,3,3a,4,7a-hexahydro-pyrano[3,4-c]pyrrole-4-carboxylic acid ethyl ester 

Relevant articles and documents

An intramolecular oxo Diels-Alder approach to 1-oxo-1,2,3,3a,4,7a- hexahydro-pyrano[3,4-c]pyrrole-4-carboxylic acid ethyl esters

The diastereoselective synthesis of a series of 1-oxo-1,2,3,3a,4,7a- hexahydro-pyrano[3,4-c]pyrrole-4-carboxylic acid ethyl esters via an oxo Diels-Alder reaction is described. Ab initio calculations predicted the products of the exo cycloaddition to be the thermodynamic products while the products resulting from the endo cycloaddition were predicted to be the kinetic products. The calculations were born out by experimental data.