283610-08-2

Basic information

• Product Name: (2R)-2-[(2'R)-2'-methyl-N-piperidinyl]-2-phenyl-1-ethyl acetate
• CAS NO: 283610-08-2
• Molecular Weight: 261.364
• Mol File: 283610-08-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R)-2-[(2'R)-2'-methyl-N-piperidinyl]-2-phenyl-1-ethyl acetate(CAS DataBase Reference)
• NIST Chemistry Reference: (2R)-2-[(2'R)-2'-methyl-N-piperidinyl]-2-phenyl-1-ethyl acetate(283610-08-2)
• EPA Substance Registry System: (2R)-2-[(2'R)-2'-methyl-N-piperidinyl]-2-phenyl-1-ethyl acetate(283610-08-2)

Safety Data

• Hazardous Substances Data: 283610-08-2(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 

Downstream Products

• 5119-88-0 (+)-(2R)-2-methylpiperidine hydrochloride 

Relevant articles and documents

A simple stereoselective synthesis of enantiopure 2-substituted pyrrolidines and piperidines from chiral (R)-phenylglycinol-derived bicyclic 1,3-oxazolidines

Chiral, nonracemic 2-substituted pyrrolidines and piperidines were prepared in high ee and moderate to good chemical yields in three steps from (R)-phenylglycinol and γ- or δ-chloroketones. The key step of the synthesis was the stereo- selective reductive ring-opening of chiral bicyclic 1,3- oxazolidines prepared by condensation of (R)-phenylglycinol and the corresponding ketones.