5119-88-0

Basic information

• Product Name: 2-METHYL-PIPERIDINE HYDROCHLORIDE
• Synonyms: 2-METHYL-PIPERIDINE HYDROCHLORIDE;(S)-2-Methylpiperidine hydrochloride;Nsc203093
• CAS NO: 5119-88-0
• Molecular Formula: C₆H₁₃N*ClH
• Molecular Weight: 0
• Mol File: 5119-88-0.mol
• Article Data: 9

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 2-METHYL-PIPERIDINE HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-METHYL-PIPERIDINE HYDROCHLORIDE(5119-88-0)
• EPA Substance Registry System: 2-METHYL-PIPERIDINE HYDROCHLORIDE(5119-88-0)

Safety Data

• Hazardous Substances Data: 5119-88-0(Hazardous Substances Data)

Usage

General Description

2-Methyl-piperidine hydrochloride is a chemical compound that consists of a piperidine ring with a methyl group attached to the second carbon. It is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals. 2-METHYL-PIPERIDINE HYDROCHLORIDE is also used as a stabilizer for some polymers and as a reagent in organic chemistry reactions. 2-Methyl-piperidine hydrochloride is a white crystalline powder that is soluble in water and alcohol. It is important to handle this chemical with care, as it can cause skin and eye irritation.

Upstream product

• 120986-91-6 B(OC₂H₅)2(CH₂)4CH(N₃)CH₃ 
• 120986-86-9 B(OH)2(CH₂)4CHBrCH₃ 
• 10294-34-5 boron trichloride 
• 1462-92-6 6-methyl-2,3,4,5-tetrahydro-pyridine 
• 175274-14-3 (2R)-1-[(1R)-2-hydroxy-1-phenylethyl]-2-methylpiperidine 
• 283610-08-2 (2R)-2-[(2'R)-2'-methyl-N-piperidinyl]-2-phenyl-1-ethyl acetate 
• 667870-56-6 1-[(S)-((R)-2-Methyl-piperidin-1-yl)-phenyl-methyl]-naphthalen-2-ol 
• 204845-25-0 (3R,5R)-5-methyl-3-phenyl-2,3,6,7,8,8a-hexahydro-5H-oxazolo[3,2-a]pyridine 
• 205526-51-8 (R)-2-[((R)-4-[1,3]Dioxolan-2-yl-1-methyl-butyl)-(2,4,6-trimethoxy-benzyl)-amino]-2-phenyl-ethanol 
• 205526-59-6 (2S,1'R)-N-2'-hydroxy-1'-phenylethyl-2-methylpiperidine 
• 191470-45-8 (3R,5S)-5-methyl-3-phenyl-2,3,5,6,7,8-hexahydro-oxazolo[3,2-a]pyridine 
• 205526-52-9 (2R,4R)-2-(3-[1,3]Dioxolan-2-yl-propyl)-4-phenyl-3-(2,4,6-trimethoxy-benzyl)-oxazolidine 
• 205526-58-5 (R)-2-[((S)-4-[1,3]Dioxolan-2-yl-1-methyl-butyl)-(2,4,6-trimethoxy-benzyl)-amino]-2-phenyl-ethanol 
• 737760-86-0 (S)-4-isopropyl-3-(6-methylpyridin-2-yl)oxazolidin-2-one 

Downstream Products

• 29808-39-7 3-(2'-methylpiperidino)-1-phenyl-propan-1-one hydrochloride 
• 103386-27-2 3-(2-methyl-piperidino)-1-(4-propoxy-phenyl)-propan-1-one 
• 93148-54-0 1-(4-methoxy-phenyl)-3-(2-methyl-piperidino)-propan-1-one; hydrochloride 
• 1599-33-3 (2-methylpiperidin-1-yl)(phenyl)methanone 
• 28720-60-7 solenopsin A 
• 1394847-39-2 3-((R)-2-methylpiperidin-1-yl)-N-(4-((3-((S)-2-methylpiperidin-1-yl)propylamino)methyl)benzyl)propan-1-amine 
• 1722-95-8 (2R)-methylpiperidine 
• 1394847-34-7 (R)-N,N'-(1,4-phenylenebis(methylene))bis(3-((R)-2-methylpiperidin-1-yl)propan-1-amine) 

Relevant articles and documents

Diethylzinc: A simple and efficient catalyst for the swift hydroamination at room temperature

Diethylzinc and dimethylanilinium tetrakis(pentafluorophenyl)borate were found to catalyze hydroaminations at room temperature in high efficiency and very short reaction times. The reactivity of the proposed cationic zinc species, which is assumed to cata

Nonracemic betti base as a new chiral auxiliary: Application to total syntheses of enantiopure (2S,6R)-dihydropinidine and (2S,6R)-isosolenopsins

(Chemical Equation Presented) Total syntheses of enantiopure alkaloidal natural products (2S,6R)-dihydropinidine (as hydrochloride) and (2S,6R)-isosolenopsins (as hydrochlorides) were achieved in four steps and in 80-82% total yields by using a synthetic strategy of the formation-cleavage of 1,3-oxazinane. (S)-Betti base was proved to be an excellent chiral auxiliary and a novel Pd/C catalyzed N-debenzylation straightforward to amine hydrochloride was developed in the presence of CH2Cl2.

Facile diastereoselective reactions of chiral 1,3-oxazolidines with grignard reagents; asymmetric syntheses of 2-substituted and 2,6-disubstituted piperidines

(S)- and (R)-2-Phenylpiperidines, (S)- and (R)-2-methylpiperidines, meso- and (2R, 6R)-2,6-diphenylpiperidines, and meso- and (25, 65)-2,6-dimethylpiperidines were synthesized asymmetrically starting from the diastereoselective addition of Grignard reagents to chiral 1,3-oxazolidines, converting of 1-aza-4-oxabicyclo[4.3.0]nonane derivatives as pivotal intermediates.