287474-35-5Relevant articles and documents
Novel heterocycles via 2-cyano-N-arylacetamide synthesis with docking studies of novel heterocycles as antimicrobial agents utilizing 2-cyano-N-arylacetamide
Abd El Salam, Hayam A.,Ewies, Ewies F.
, p. 1075 - 1085 (2020/04/17)
2-CYANO-N-arylacetamide reagent is used in a straight forward synthesis of various interesting nitrogenous heterocycles such as iminocoumarine, thiazole, dihydropyridine and imidazole or benzoimidazole. Molecular docking studies are described to show the most active compounds as antimicrobial agents. Also, Biological testing of these compounds for their antimicrobial activities against some strains of Gram bacteria and strains of fungi has been carried out.