28757-27-9 Usage
Description
5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone is a flavonoid compound characterized by the presence of a β-D-glucopyranosyloxy group at the 5-position and hydroxyl groups at the 4' and 7 positions. This molecule is derived from the flavone class of flavonoids, which are known for their diverse biological activities and potential health benefits.
Uses
Used in Pharmaceutical Applications:
5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone is used as an intermediate in the synthesis of various flavonoid compounds with potential pharmaceutical applications. Its ability to induce the reversion of transformed phenotypes in cells and inhibit the proliferation of malignant tumor cells makes it a promising candidate for cancer research and treatment.
Used in Drug Delivery Systems:
In the field of drug delivery, 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone can be utilized as a component in the development of novel drug delivery systems. Its structural features may allow for improved targeting and bioavailability of therapeutic agents, potentially enhancing their efficacy in treating various diseases, including cancer.
Used in Antioxidant Applications:
Given the antioxidant properties commonly associated with flavonoids, 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone may also be used as an antioxidant in the pharmaceutical and nutraceutical industries. Its ability to protect cells from oxidative stress could contribute to the development of products aimed at promoting overall health and well-being.
Used in Cosmetics Industry:
5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone may find application in the cosmetics industry due to its potential antioxidant and anti-inflammatory properties. These characteristics could be harnessed in the development of skincare products designed to protect and rejuvenate the skin, promoting a healthier and more youthful appearance.
Used in Functional Foods and Beverages:
The potential health benefits of 5-[(β-D-Glucopyranosyl)oxy]-4',7-dihydroxyflavone may also make it a valuable ingredient in the development of functional foods and beverages. Its incorporation into these products could provide consumers with additional health-promoting properties, such as enhanced immune function or improved cardiovascular health.
Check Digit Verification of cas no
The CAS Registry Mumber 28757-27-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,8,7,5 and 7 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 28757-27:
(7*2)+(6*8)+(5*7)+(4*5)+(3*7)+(2*2)+(1*7)=149
149 % 10 = 9
So 28757-27-9 is a valid CAS Registry Number.
28757-27-9Relevant articles and documents
Differentially evolved glucosyltransferases determine natural variation of rice flavone accumulation and UV-tolerance
Peng, Meng,Shahzad, Raheel,Gul, Ambreen,Subthain, Hizar,Shen, Shuangqian,Lei, Long,Zheng, Zhigang,Zhou, Junjie,Lu, Dandan,Wang, Shouchuang,Nishawy, Elsayed,Liu, Xianqing,Tohge, Takayuki,Fernie, Alisdair R.,Luo, Jie
, (2017/12/26)
Decoration of phytochemicals contributes to the majority of metabolic diversity in nature, whereas how this process alters the biological functions of their precursor molecules remains to be investigated. Flavones, an important yet overlooked subclass of flavonoids, are most commonly conjugated with sugar moieties by UDP-dependent glycosyltransferases (UGTs). Here, we report that the natural variation of rice flavones is mainly determined by OsUGT706D1 (flavone 7-O-glucosyltransferase) and OsUGT707A2 (flavone 5-O-glucosyltransferase). UV-B exposure and transgenic evaluation demonstrate that their allelic variation contributes to UV-B tolerance in nature. Biochemical characterization of over 40 flavonoid UGTs reveals their differential evolution in angiosperms. These combined data provide biochemical insight and genetic regulation into flavone biosynthesis and additionally suggest that adoption of the positive alleles of these genes into breeding programs will likely represent a potential strategy aimed at producing stress-tolerant plants.
