520-36-5Relevant articles and documents
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Dranik
, (1970)
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Regioselective ortho-Hydroxylations of Flavonoids by Yeast
Sordon, Sandra,Madej, Anna,Pop?oński, Jaros?aw,Bartmańska, Agnieszka,Tronina, Tomasz,Brzezowska, Ewa,Juszczyk, Piotr,Huszcza, Ewa
, p. 5525 - 5530 (2016)
Natural flavonoids, such as naringenin, hesperetin, chrysin, apigenin, luteolin, quercetin, epicatechin, and biochanin A, were subjected to microbiological transformations by Rhodotorula glutinis. Yeast was able to regioselectively C-8 hydroxylate hesperetin, luteolin, and chrysin. Naringenin was transformed to 8- and 6-hydroxyderivatives. Quercetin, epicatechin, and biochanin A did not undergo biotransformation. A metabolic pathway for the degradation of chrysin has been elucidated. The metabolism of chrysin proceeds via an initial C-8 hydroxylation to norwogonin, followed by A-ring cleavage to 4-hydroxy-6-phenyl-2H-pyran-2-one.
Secondary metabolites of an Algerian Phlomis bovei and their antioxidant activities
Zaabat,Akkal,Darboure,Laouer,Franca, M. G. Dijoux,Duddeck, Helmut
, p. 454 - 455 (2010)
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Gusev et al.
, (1977)
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FLAVONOID GLYCOSIDES OF ARTEMISIA MONOSPERMA AND A. HERBA-ALBA
Saleh, Nabiel A. M.,El-Negoumy, Sabry I.,Abd-Alla, Mohamed F.,Abou-Zaid, Mamdouh M.,Dellamonica, G.,Chopin, J.
, p. 201 - 203 (1985)
Ten flavonoid glycosides were isolated and identified from Artemisia monosperma: vicenin-2, lucenin-2, acacetin 7-glucoside, acacetin 7-rutinoside, the 3-glucosides and 3-rutinosides of quercetin and patuletin, and the 5-glucosides of quercetin and isorhamnetin.From Artemisia herba-alba eight flavonoid glycosides were isolated and identified: isovitexin, vicenin-2, schaftoside, isoschaftoside and the 3-glucosides and 3-rutinosides of quercetin and patuletin.Key Word Index - Artemisia monosperma; A herba-alba; Compositae; flavone and flavonol glycosides.
A NEW GLYCOSYLATED FLAVONOID, 7-O-α-L-RHAMNOPYRANOSYL-4'-O-RUTINOSYLAPIGENIN, IN THE EXUDATE FROM GERMINATING SEEDS OF Sesbania rostrata
Messems, Eric,Montagu, Marc Van,Bruyn, Andre De,Jans, Arnold W. H.
, p. 241 - 254 (1989)
The title apigenin triglycoside was isolated (4 mg/6000 seeds) by reversephase column chromatography as the major u.v.-absorbing compound in the exudate of germinating seeds of Sesbania rostrata.The structure was assigned on the basis of u.v. spectra, f.a.b.-mass-spectral and 2D-n.m.r. data.The triglycoside was released continuously from the germinating seeds, but at a decreasing rate during the first two weeks.
Apigenin Glycosides from Astragalus galegiformis
Kavtaradze,Alaniya,Pichette,Mshvildadze
, p. 156 - 157 (2021/01/29)
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8-azacyclo-substituted chromone derivative as well as preparation method and pharmaceutical application thereof
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Paragraph 0051-0053, (2021/10/27)
The invention discloses an 8-azacyclo-substituted chromone derivative as well as a preparation method and pharmaceutical application thereof, and belongs to the field of medicinal chemistry. The invention provides the 8-azacyclo-substituted chromone compound with selective PARP1/2 inhibitory activity, and the 8-azacyclo-substituted chromone compound can be used for preparing medicines for preventing or treating PARP1/2 defective tumors and has wide market application and development prospects.