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Kono Chem Co.,Ltd

Superiority Kono Chem is a leading manufacturer and supplier of chemicals in China. We develop ,produce and distribute high quality pharmaceuticals, intermediates, special chemicals and other fine chemicals. We could give you: 1.Best quali

Apigenin

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $800.0 / 1000.0

Type:Other

inquiry

Greenutra Resource Inc

Celery Seed Extract Plant Origin: Apium graveolens Appearance: Yellow brown fine powder Specification: 1. 5:1, 10:1, 20:1 2. Apigenin: 1%,5%,80%,85%,90%,95%,98% Introduction: Tripterygium wilfordii, sometimes

Celery Seed Extract

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $10.5

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Apigenin Manufacturer/High quality/Best price/In stock

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Appearance Light yellow powder, Characteristic Complies Assay 98%min

High purity Apigenin with high quality cas:520-36-5

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $520.0 / 700.0

Type:Manufacturers

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

98% HPLC celery leaf extract Anti-cancer Apigenin powder

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $1.0 / 12.0

Type:Trading Company

inquiry

Jinan Finer Chemical Co., Ltd

Product description: Product name Apigenin CAS number 520-36-5 Assay ≥99% Appearance Light yellow crystalline solid Capacity 200mt/year Application Estrogen synthase inhibito

Apigenin

Cas:520-36-5

Min.Order:10 Gram

FOB Price: $12.0

Type:Lab/Research institutions

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

High quality Apigenin

Cas:520-36-5

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Xi'an Quanao Biotech Co., Ltd.

Comes from Natural Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion of extract according to the demand . Appearance:Light Yellow

Appeasable Skincare raw material API Chamomile Extract Apigenin Powder

Cas:520-36-5

Min.Order:500 Gram

FOB Price: $0.5 / 0.75

Type:Manufacturers

inquiry

Hefei TNJ chemical industry co.,ltd

Product Name: Camomile Extract /Chamomile Extract Latin Name: Matricaria recutita L Active Ingredient: Apigenin Specifications: Apigenin 1.2%, 2%, 10%, 98%; 4:1, 10:1 Test Methord: HPLC Apprearance: Light yellow powder. CAS No: 520-36-5

Camomile Extract

Cas:520-36-5

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Apigenin

Cas:520-36-5

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Apigenin 520-36-5 GMP manufacturer

Cas:520-36-5

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Apigenin

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Apigenin

Cas:520-36-5

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Apigenin -- CHemwill

Cas:520-36-5

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:Apigenin The alias:5,7,4 '-trihydroxyflavone, carvaxanthin English Name: Apigenin CAS No.520-36-5 Molecular formula:C15H10O5 Molecular weight:270.25 Packaging Specification: 25kg/drum high purity 99%min stock Hubei DiBo Chemical

Apigenin material/powder /CAS:520-36-5

Cas:520-36-5

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

Apigenin

Cas:520-36-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. High quality and competitive price: 1) Standard: BP/USP/EP/ enterprise standard 2) All purity ≥99% 3) We are manufacturers and can provide high quality products at factory prices. 2. Fast and safe delivery 1) The package c

Apigenin CAS:520-36-5.

Cas:520-36-5

Min.Order:20 Metric Ton

FOB Price: $299.0 / 399.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 520-36-5 with best quality

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Product Name: Apigenin Chemical formula: C15H10O5 Molecular weight: 270.24 CAS: 520-36-5 Melting point: 347 ~ 348 ℃ Appearance: light yellow powder Specification Apigenin 1.2%, 3%, 90%, 95%, 98% , 4:1 10:1 Detection method: HPLC Appearance:

Apigenin CAS: 520-36-5

Cas:520-36-5

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Light Yellow Fine Powder Storage:Store in sealed containers

HANWAYS CHEMPHARM CO.,LIMITED

Hanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr

FActory Supply pure apigenin 98% with best price apigenin powder

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $20.0 / 40.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Apigenin 520-36-5

Cas:520-36-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Apigenin is a polyphenol, and is one of the flavonoids found in many of the foods consumed by humans. Technically, it is a flavone with three OH groups on it. This compound is being widely studied for its anti-cancer properties. In particular, it

4',5,7-TRIHYDROXYFLAVONE,Apigenin,cas:520-36-5

Cas:520-36-5

Min.Order:1 Kilogram

FOB Price: $760.0 / 840.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Apigenin CAS:520-36-5 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, ste

Apigenin CAS:520-36-5

Cas:520-36-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Apigenin

Cas:520-36-5

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Wonda Pharm Limited

1.High Quality: Quality is life. Quality is the most important element for all goods. We have a lab doing research in Wuhan China and produce sarms in bulk quantity. We have 8 years experience making all kinds of sarms. And all our old customers

Apigenin supplement /Chamomile extract/CAS No.520-36-5

Cas:520-36-5

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Lonwin Chemical Group Limited

Apigenin CAS: 520-36-5 Specification identification standardization aspect yellow brown powder odor & taste characteristic particle size

Factory supply Apigenin

Cas:520-36-5

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Leader Biochemical Group

PRODUCT DETAILS

The world Biggest Manufacturer factory sales Apigenin CAS 520-36-5

Cas:520-36-5

Min.Order:500 Kilogram

FOB Price: $1.0 / 2.0

Type:Lab/Research institutions

inquiry

ShangHai Soyoung Biotechnology Inc

Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye

Celery seed extract 90%-98% apigenin

Cas:520-36-5

Min.Order:25 Kilogram

FOB Price: $150.0

Type:Lab/Research institutions

inquiry

Xi'an Yinherb Bio-Tech Co., Ltd.

Xi'an Yinherb Bio-Tech Co., Ltd was founded in 2009, We have more than 10 experienced doctors and scientists and professional managers, specializing in Nootropics, Sarms and Peptides researching and developing, and become the lead

Yinherb Supply Natural Celery Extract 98% Apigenin CAS 520-36-5 Raw Powder

Cas:520-36-5

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2,4’,5,7-tetrahydroxyflavanone

2,4’,5,7-tetrahydroxyflavanone

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogenchloride In methanol; water100%
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on
480-41-1

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With sulfuric acid; iodine In dimethyl sulfoxide at 100℃; for 1.5h;95%
With pyridine; iodine for 4h; Heating;93%
With pyridine; iodine at 95℃; for 5h;66%
apigenin 7-O-glucoside
578-74-5

apigenin 7-O-glucoside

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogenchloride for 2h; Heating;95%
Acid hydrolysis;
Acidic conditions;
2-chloro-1-(2,4,6-trihydroxyphenyl)ethan-1-one
110865-03-7

2-chloro-1-(2,4,6-trihydroxyphenyl)ethan-1-one

4-hydroxy-benzaldehyde
123-08-0

4-hydroxy-benzaldehyde

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
Stage #1: 2-chloro-1-(2,4,6-trihydroxyphenyl)ethan-1-one; 4-hydroxy-benzaldehyde With sodium hydroxide In ethanol; water
Stage #2: With hydrogenchloride Further stages.;
92%
Stage #1: 4-hydroxy-benzaldehyde With potassium hydroxide In ethanol; water for 0.166667h; Inert atmosphere;
Stage #2: 2-chloro-1-(2,4,6-trihydroxyphenyl)ethan-1-one In ethanol; water at 60℃; for 4h;
90%
With potassium hydroxide In ethanol at 20 - 60℃; for 6h;83%
4',5,7-trimethoxyflavone
5631-70-9

4',5,7-trimethoxyflavone

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With pyridine hydrochloride at 180 - 190℃; for 6h; Inert atmosphere;90%
With pyridine hydrochloride at 180℃; for 6h; Inert atmosphere;90%
With boron tribromide In dichloromethane at 20℃; for 24h; Inert atmosphere;90%
Stage #1: 4',5,7-trimethoxyflavone With aluminum (III) chloride In toluene at 80 - 140℃;
Stage #2: With hydrogenchloride In water; toluene at 0℃; Reagent/catalyst; Solvent; Temperature; Time;
61.5%
With hydrogen iodide In acetic anhydride at 115 - 118℃; for 6h;10 g
naringenin
480-41-1

naringenin

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With iodine In pyridine at 90℃; for 8h;86%
With flavone synthase I Product distribution;
With GLUTATHIONE; N-[tris(hydroxymethyl)methyl]glycine; flavone synthase II; NADPH; potassium hydroxide at 25℃; for 0.5h; pH=7.9; Enzymatic reaction;
With 2,3-dicyano-5,6-dichloro-p-benzoquinone
2',4',6',4-tetrahydroxydihydrochalcone
25515-46-2, 73692-50-9

2',4',6',4-tetrahydroxydihydrochalcone

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With oxygen at 20℃; under 760.051 Torr; for 0.866667h; Reagent/catalyst;77%
1-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-3-(2,4,6-trihydroxy-phenyl)-propane-1,3-dione

1-[4-(tert-Butyl-dimethyl-silanyloxy)-phenyl]-3-(2,4,6-trihydroxy-phenyl)-propane-1,3-dione

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With sulfuric acid In acetic acid at 95 - 100℃; for 1h;76%
3,5-dihydroxyphenol
108-73-6

3,5-dihydroxyphenol

ethyl (4-hydroxybenzoyl)acetate
77103-47-0

ethyl (4-hydroxybenzoyl)acetate

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
for 0.0633333h; microwave irradiation;66%
C27H18O9S2

C27H18O9S2

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With potassium carbonate In methanol at 65℃; for 5h; Inert atmosphere;66%
7-benzyloxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one
874202-29-6

7-benzyloxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one

A

7-O-benzylapigenin
20450-81-1

7-O-benzylapigenin

B

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
Stage #1: 7-benzyloxy-5-hydroxy-2-(4-hydroxyphenyl)chroman-4-one With pyridine; iodine for 4h; Heating / reflux;
Stage #2: With hydrogenchloride In water
A 58%
B 24%
4,6-bis(methoxymethyl)-2-(4-acetoxybenzoyloxy)acetophenone

4,6-bis(methoxymethyl)-2-(4-acetoxybenzoyloxy)acetophenone

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
Stage #1: 4,6-bis(methoxymethyl)-2-(4-acetoxybenzoyloxy)acetophenone With potassium hydroxide In pyridine at 50℃; for 0.333333h;
Stage #2: With acetic acid In pyridine; water for 0.5h;
Stage #3: With hydrogenchloride In methanol Reflux;
58%
4',5,7-trimethoxyflavone
5631-70-9

4',5,7-trimethoxyflavone

A

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

B

5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one
480-44-4

5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With N-butyl-N-methylimidazolium heptachlorodialuminate In dichloromethane at 40℃; for 4h;A 54%
B 16%
apigenin 7-O-[β-D-glucuronopyranosyl-(1->2)]-O-β-D-glucuronopyranoside

apigenin 7-O-[β-D-glucuronopyranosyl-(1->2)]-O-β-D-glucuronopyranoside

A

D-Glucuronic acid
6556-12-3

D-Glucuronic acid

B

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
Acid hydrolysis;A n/a
B 52%
5,7-dihydroxy-2-phenyl-chromen-4-one
480-40-0

5,7-dihydroxy-2-phenyl-chromen-4-one

A

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

B

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on
491-70-3

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

C

luteolin 3'-monosulphate

luteolin 3'-monosulphate

Conditions
ConditionsYield
With Mucore ramannianus (ATCC 9628) In N,N-dimethyl-formamide for 336h; Microbiological reaction;A 3%
B 10.2%
C 10.2%
5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on
480-41-1

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on

A

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

B

eriodictyol
4049-38-1

eriodictyol

Conditions
ConditionsYield
With plasmid pFusionF87V-carrying recombinant Escherichia coli BL21 (DE3) cells at 28℃; for 24h; Microbiological reaction;A 3.7%
B 5.2%
5,7-dihydroxy-2-phenyl-chromen-4-one
480-40-0

5,7-dihydroxy-2-phenyl-chromen-4-one

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With Aspergillus alliaceous (ATCC 10060) In N,N-dimethyl-formamide for 336h; Microbiological reaction;4.1%
6-bromo-5-hydroxy-7,4'-dimethoxyflavone
35095-48-8

6-bromo-5-hydroxy-7,4'-dimethoxyflavone

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogen iodide; acetic anhydride
dihydrokaempferol
724434-08-6

dihydrokaempferol

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With sulfuric acid
4'-O-methylapigenin 6-C-β-D-glucopyranoside
21089-34-9

4'-O-methylapigenin 6-C-β-D-glucopyranoside

A

D-Glucose
2280-44-6

D-Glucose

B

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogenchloride; water In acetic acid at 100℃; for 24h;
With iron(III) chloride at 100℃; for 6h;
FLAVONE
525-82-6

FLAVONE

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With pyridine hydrochloride
5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
5128-44-9

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With pyridine hydrochloride at 170℃; for 2h; Product distribution; for identification of structure;
apigenin 7-p-coumarate
126661-94-7

apigenin 7-p-coumarate

A

p-Coumaric Acid
7400-08-0

p-Coumaric Acid

B

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With sodium hydroxide for 0.5h; Ambient temperature;
crotonoylcosmosiin
123656-62-2

crotonoylcosmosiin

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogenchloride In methanol for 5h; Heating;6 mg
apigenin 7-(4-O-β-glucosyl-trans-p-coumarate)
126871-97-4

apigenin 7-(4-O-β-glucosyl-trans-p-coumarate)

A

D-Glucose
2280-44-6

D-Glucose

B

p-Coumaric Acid
7400-08-0

p-Coumaric Acid

C

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogenchloride Heating;
With hydrogenchloride Heating;
2-hydroxynaringenin
64325-11-7

2-hydroxynaringenin

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With hydrogenchloride In acetic acid for 1h; Heating; Yield given;
With hydrogenchloride; acetic acid at 100℃; for 1.5h; Yield given;
nivyaside
84563-91-7

nivyaside

A

D-Glucose
2280-44-6

D-Glucose

B

cyclohexanetetrol-(1r,2t,3t,4c)
20089-18-3, 907575-48-8

cyclohexanetetrol-(1r,2t,3t,4c)

C

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With Kiliani's mixture for 6h; Heating;A n/a
B n/a
C 36 mg
apigenin 5-O-α-L-rhamnopyranosyl-(1'''->2'')-6''-O-acetyl-β-D-glucopyranoside
125300-52-9

apigenin 5-O-α-L-rhamnopyranosyl-(1'''->2'')-6''-O-acetyl-β-D-glucopyranoside

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
sulfuric acid In ethanol; water for 6h; Heating;
chlorosulfuric acid 2,2,2-trichloroethyl ester
764-09-0

chlorosulfuric acid 2,2,2-trichloroethyl ester

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

C21H13Cl9O14S3

C21H13Cl9O14S3

Conditions
ConditionsYield
With dmap; triethylamine In tetrahydrofuran at 20℃;95%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on
491-70-3

2-(3,4-Dihydroxy-phenyl)-5,7-dihydroxy-chromen-4-on

Conditions
ConditionsYield
With C9H8IO4Pol In dimethyl sulfoxide at 25℃; for 2h;95%
With cytochromes P450 in human liver microsomes Kinetics; Enzymatic reaction;
2-iodo-propane
75-30-9

2-iodo-propane

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5-hydroxy-7-isopropoxy-2-(4-isopropoxyphenyl)-4H-chromen-4-one

5-hydroxy-7-isopropoxy-2-(4-isopropoxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 30h; Inert atmosphere;95%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

C15H8F2O9S2

C15H8F2O9S2

Conditions
ConditionsYield
With fluorosulfonyl fluoride In acetonitrile at 20℃; for 3h; Sealed tube;95%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
5128-44-9

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
In methanol; diethyl ether at 20℃; for 0.5h;94%
With ethanol
In methanol at 20℃; for 1h;
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

acetic anhydride
108-24-7

acetic anhydride

apigenin triacetate
3316-46-9

apigenin triacetate

Conditions
ConditionsYield
With pyridine at 70℃; for 6h;94%
With pyridine at 140℃; for 8h; Temperature;90.8%
With pyridine Reflux;87.2%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

diethyl 2,2'-((2-(4-(2-ethoxy-2-oxoethoxy)phenyl)-4-oxo-4H-chromene-5,7-diyl)bis(oxy))diacetate

diethyl 2,2'-((2-(4-(2-ethoxy-2-oxoethoxy)phenyl)-4-oxo-4H-chromene-5,7-diyl)bis(oxy))diacetate

Conditions
ConditionsYield
Stage #1: 5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 0.75h;
Stage #2: chloroacetic acid ethyl ester In N,N-dimethyl-formamide at 20℃; for 24h;
94%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

6,8-dibromo-5,7,4'-trihydroxyflavone
1006032-73-0

6,8-dibromo-5,7,4'-trihydroxyflavone

Conditions
ConditionsYield
With N-Bromosuccinimide In trifluoroacetic acid at 20℃; for 5h;93%
With N-Bromosuccinimide In acetone at 22℃; for 0.716667h;
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on
480-41-1

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on

Conditions
ConditionsYield
With palladium 10% on activated carbon; hydrogen at 20℃;91%
With palladium 10% on activated carbon; hydrogen25%
europium(III) oxide

europium(III) oxide

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

water
7732-18-5

water

C45H27EuO15*2H2O

C45H27EuO15*2H2O

Conditions
ConditionsYield
With dihydrogen peroxide; nitric acid; triethylamine In ethanol at 20℃; for 20h; pH=8; Reagent/catalyst; Darkness;90.93%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

benzoyl chloride
98-88-4

benzoyl chloride

5,7,4'-tribenzoyloxyflavone

5,7,4'-tribenzoyloxyflavone

Conditions
ConditionsYield
With pyridine hydrochloride at 140 - 200℃; for 9h;89%
With potassium hydroxide
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

7,4'-di-O-(tert-butyldimethylsilyl)apigenin

7,4'-di-O-(tert-butyldimethylsilyl)apigenin

Conditions
ConditionsYield
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 20℃; for 5h;89%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

Hexanoyl chloride
142-61-0

Hexanoyl chloride

5,7,4'-tri-O-hexanoyl apigenin
1145669-46-0

5,7,4'-tri-O-hexanoyl apigenin

Conditions
ConditionsYield
With dmap; triethylamine In N,N-dimethyl-formamide for 8h; Cooling with ice;88%
With dmap; triethylamine In N,N-dimethyl-formamide at 20℃; for 4.5h; Cooling with ice;87%
With dmap; triethylamine In N,N-dimethyl-formamide
methyl 6-bromohexanoate
14273-90-6

methyl 6-bromohexanoate

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

methyl 6-((5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)hexanoate

methyl 6-((5-hydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-chromen-7-yl)oxy)hexanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 70℃; for 6h; Inert atmosphere;87%
With potassium carbonate In N,N-dimethyl-formamide at 80℃; for 6h;20%
4-chloro-3,5-dinitrobenzotrifluoride
393-75-9

4-chloro-3,5-dinitrobenzotrifluoride

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

7-(2,6-dinitro-4-(trifluoromethyl)phenoxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

7-(2,6-dinitro-4-(trifluoromethyl)phenoxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
With potassium tert-butylate In N,N-dimethyl-formamide at 20℃;84%
formaldehyd
50-00-0

formaldehyd

furan-2-ylmethanamine
617-89-0

furan-2-ylmethanamine

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

C36H31N3O8

C36H31N3O8

Conditions
ConditionsYield
In dimethyl sulfoxide at 100℃; for 12h;84%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5,7-dihydroxy-2-(4-hydroxyphenyl-3,5-D2)-4H-1-benzopyran-4-one-3,6,8-D3
263711-74-6

5,7-dihydroxy-2-(4-hydroxyphenyl-3,5-D2)-4H-1-benzopyran-4-one-3,6,8-D3

Conditions
ConditionsYield
With boron trifluoride; [D3]phosphoric acid In water-d2 at 55℃; for 96h; deuteration;83%
Multi-step reaction with 3 steps
1: D2O / acetone
2: 1-butyl-3-methylimidazolium chloride; DCl; D2O / 0.33 h / 120 °C / 3750.38 Torr / microwave irradiation
3: H2O
View Scheme
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

diethyl chlorophosphate
814-49-3

diethyl chlorophosphate

C27H37O14P3

C27H37O14P3

Conditions
ConditionsYield
With dmap; triethylamine In tetrahydrofuran at 20℃; for 24.5h; Inert atmosphere; Cooling with ice;83%
With dmap; triethylamine In tetrahydrofuran at 70℃; for 3.5h; Cooling with ice; Inert atmosphere;
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

acetic anhydride
108-24-7

acetic anhydride

7,4'-diacetoxy-5-hydroxyflavone
857-79-4

7,4'-diacetoxy-5-hydroxyflavone

Conditions
ConditionsYield
82%
With pyridine
With pyridine at 20℃; for 24h;
2-iodo-propane
75-30-9

2-iodo-propane

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

5,7-diisopropoxy-2-(4-isopropoxyphenyl)-4H-benzopyran-4-one

5,7-diisopropoxy-2-(4-isopropoxyphenyl)-4H-benzopyran-4-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide for 24h; Inert atmosphere;82%
With potassium carbonate In N,N-dimethyl-formamide at 60℃; for 24h; Inert atmosphere;78%
With potassium carbonate In N,N-dimethyl-formamide73%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

A

C15H9O8S(1-)*K(1+)
120562-19-8

C15H9O8S(1-)*K(1+)

B

C15H8O11S2(2-)*2K(1+)
116097-08-6

C15H8O11S2(2-)*2K(1+)

Conditions
ConditionsYield
With potassium acetate; tetra(n-butyl)ammonium hydrogensulfate; dicyclohexyl-carbodiimide In pyridine at 4℃; for 72h; Yields of byproduct given;A n/a
B 81%
With potassium acetate; tetra(n-butyl)ammonium hydrogensulfate; dicyclohexyl-carbodiimide In pyridine at 4℃; for 72h; Yields of byproduct given;A 28%
B n/a
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

diazomethyl-trimethyl-silane
18107-18-1

diazomethyl-trimethyl-silane

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
5128-44-9

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
In methanol; hexane; dichloromethane at 20℃; for 12h;81%
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

dimethyl sulfate
77-78-1

dimethyl sulfate

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one
5128-44-9

5-hydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-chromen-4-one

Conditions
ConditionsYield
With potassium hydroxide In water; acetone at 20℃; for 4h;80%
With potassium hydroxide
With sodium hydroxide
With potassium carbonate regioselective reaction;
With potassium carbonate In acetone at 65℃;
5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
520-36-5

5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one

methyl iodide
74-88-4

methyl iodide

5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one
480-44-4

5,7-dihydroxy-2-(4'-methoxyphenyl)-4H-1-benzopyran-4-one

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 18h; Inert atmosphere; regiospecific reaction;79%
With potassium carbonate In N,N-dimethyl-formamide for 2h;
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