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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

5-Difluoromethoxy-2-Mercapto-1H-Benzimidazole

Cas:97963-62-7

Min.Order:0

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Type:Manufacturers

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AstaTech ( Chengdu) BioPharmaceutical Corp.

Chengdu AstaTech Chemical Technology Co., Ltd. is a wholly-owned subsidiary of AstaTech (Chengdu) BioPharmaceutical Co., Ltd. It has overall accountability for AstaTech’s product list and sales and promotion of chemical reagents in China. The c

97963-62-7

Cas:97963-62-7

Min.Order:0 Metric Ton

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 5-Difluoromethoxy-2-Mercapto-1H-Benzimidazole supplier in China

Cas:97963-62-7

Min.Order:0 Metric Ton

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Light beige powder Storage:cool dry place Package:1kg/foil bag;25kg/drum Application:pharmaceutical intermediate T

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1

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Type:Other

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Anhui Dexinjia Biopharm Co., Ltd

As a leading and professional manufacturer of APIs and API intermediates in China,Anhui Dexinjia Biopharm Co., Ltd founded in 2006, Except for the R&D center, our company has built a close cooperation relation with Chinese Academy of Sciences, T

5-Difluoromethoxy-2-mercapto-1-H-benzimidazole

Cas:97963-62-7

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Assay: 99% up; Stable supply with over 50Mt annually; Appearance:light-yellow powder Storage:room temprature Package:1kg/bag, 25kg/drum Application:Intermediate of Pantoprazole Port:Beijing/Shanghai/Shenzhen/Hangzhou

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole, Pantoprazole Intermediate 97963-62-7

Cas:97963-62-7

Min.Order:1 Kilogram

FOB Price: $115.0 / 145.0

Type:Trading Company

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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole Manufacturer/High quality/Best price/In stock

Cas:97963-62-7

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1. All inquiries will be replied within 12 hours. 2. Dedication to quality, supply & service. 3. Strictly on selecting raw materials. 4. Reasonable & competitive price, fast lead time. 5. Sample is available for your eva

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Gram

FOB Price: $1000.0 / 1300.0

Type:Trading Company

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole 97963-62-7

Cas:97963-62-7

Min.Order:1 Metric Ton

FOB Price: $500.0

Type:Lab/Research institutions

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 97963-62-7 with best quality

Cas:97963-62-7

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole/ LIDE PHARMA- Factory supply / Best price

Cas:97963-62-7

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole 97963-62-7

Cas:97963-62-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole/CAS:97963-62-7

Cas:97963-62-7

Min.Order:1 Kilogram

FOB Price: $31.0 / 45.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole CAS: 97963-62-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole CAS: 97963-62-7

Cas:97963-62-7

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:97963-62-7

Cas:97963-62-7

Min.Order:0

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Afine Chemicals Limited

Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Kilogram

FOB Price: $1.0 / 100000.0

Type:Lab/Research institutions

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Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS97963-62-7 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Kilogram

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Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:0

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Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:100 Gram

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Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 5-Difluoromethoxy-2-Mercapto-1H-Benzimidazole

Cas:97963-62-7

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

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Siwei Development Group Ltd.

Product name: 5-Difluoromethoxy-2- Mercapto-1H-Benzimidazole CAS No.: 97963-62-7 Molecule Formula:C8H6F2N2OS Molecule Weight:216.21 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard

Lower Price 5-Difluoromethoxy-2- Mercapto-1H-Benzimidazole on stock

Cas:97963-62-7

Min.Order:1 Kilogram

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Type:Lab/Research institutions

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Hangzhou Huarong Pharm Co., Ltd.

Huarong Industrial Group Limited established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World.

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Gram

FOB Price: $1.0 / 2.0

Type:Trading Company

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Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Jiangsu Qianyu Molecular Technology Co., LTD.

Our Advantages A. International Top level TechnologyOur company owned biomedicine experts are famous at home and abroad with rich experience in research and development in the field of efficient chiral functional molecules research and development an

Buy Top Purity 5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:0

Negotiable

Type:Trading Company

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Shanghai Minstar Chemical Co., Ltd

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole Chemical Properties Melting point 239-243 °C(lit.) Boiling point 303.5±52.0 °C(Predicted) density 1.52±0.1 g/cm3(Predicted) storage temp. Sealed in dry,Store in fre

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Gram

FOB Price: $66.0

Type:Lab/Research institutions

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EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

5-(Difluoromethoxy)-2-mercapto-1H-benzimidazole

Cas:97963-62-7

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

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Synthetic route

carbon disulfide
75-15-0

carbon disulfide

4-(difluoromethoxy)benzene-1,2-diamine
172282-50-7

4-(difluoromethoxy)benzene-1,2-diamine

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

Conditions
ConditionsYield
Stage #1: 4-(difluoromethoxy)benzene-1,2-diamine With sodium carbonate In water for 0.333333h; Reflux; Green chemistry;
Stage #2: carbon disulfide In water at 25 - 70℃; for 12h; Temperature; Reagent/catalyst; Green chemistry;
95.4%
With sodium hydroxide In methanol for 4h; Reflux;94.5%
With sodium carbonate In water at 20 - 70℃; for 12h;77 mg
In ethanol at 60℃; for 5h;
3,4-dinitophenol
577-71-9

3,4-dinitophenol

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: caesium carbonate / N,N-dimethyl-formamide / 20 °C
2: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C
3: sodium carbonate / water / 12 h / 20 - 70 °C
View Scheme
4-(difluoromethoxy)-1,2-dinitrobenzene

4-(difluoromethoxy)-1,2-dinitrobenzene

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: palladium 10% on activated carbon; hydrogen / methanol / 12 h / 20 °C
2: sodium carbonate / water / 12 h / 20 - 70 °C
View Scheme
tert-butyl 5-(3-(4-fluorophenyl)-7-(5-((methylsulfonyloxy)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate
1373279-03-8

tert-butyl 5-(3-(4-fluorophenyl)-7-(5-((methylsulfonyloxy)methyl)isoxazol-3-yl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

tert-butyl 5-(7-(5-((5-(difluoromethoxy)-1h-benzo[d]imidazol-2-ylthio)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate
1373279-04-9

tert-butyl 5-(7-(5-((5-(difluoromethoxy)-1h-benzo[d]imidazol-2-ylthio)methyl)isoxazol-3-yl)-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-yl)pentanoate

Conditions
ConditionsYield
With potassium carbonate In acetone at 70℃; for 3h;100%
2-chloromethyl-3,4-dimethoxypyridine-N-oxide
953787-47-8

2-chloromethyl-3,4-dimethoxypyridine-N-oxide

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-2-[[(3,4-dimethoxypyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzoimidazole
953787-51-4

5-(difluoromethoxy)-2-[[(3,4-dimethoxypyridin-2-yl-1-oxide)methyl]sulfanyl]-1H-benzoimidazole

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 20℃;98.44%
With sodium hydroxide In tetrahydrofuran; water at 20 - 30℃; for 2h; Solvent; Temperature;92.4%
ClH*C8H12ClNO2

ClH*C8H12ClNO2

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

pantoprazole sulfide
102625-64-9

pantoprazole sulfide

Conditions
ConditionsYield
With sodium carbonate In tetrahydrofuran; water at 30 - 50℃; for 2h;98.14%
C11H9ClN4O
1228006-40-3

C11H9ClN4O

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

C19H14F2N6O2S
1228006-45-8

C19H14F2N6O2S

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 1h;98%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride
72830-09-2

2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride

pantoprazole sulfide
102625-64-9

pantoprazole sulfide

Conditions
ConditionsYield
With sodium hydroxide In water at 25 - 30℃; for 4 - 5h;97.5%
With sodium hydroxide In methanol; water at 10 - 40℃; for 2.5h;95.3%
With sodium hydroxide In methanol; water at 40 - 55℃; for 3.5h; Temperature; Solvent;93%
C11H9ClN4
1228006-38-9

C11H9ClN4

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

C19H14F2N6OS
1228006-43-6

C19H14F2N6OS

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 1h;97%
2-chloromethyl-3,4-bis(trideuteriomethoxy)pyridinium chloride

2-chloromethyl-3,4-bis(trideuteriomethoxy)pyridinium chloride

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-difluoromethoxy-2-[(3,4-bis(trideuteriomethoxy)-2-pyridinyl)methylthio]-1H-benzimidazole

5-difluoromethoxy-2-[(3,4-bis(trideuteriomethoxy)-2-pyridinyl)methylthio]-1H-benzimidazole

Conditions
ConditionsYield
With sodium hydroxide In ethanol; water at 50 - 55℃; for 1 - 2h;95%
With sodium hydroxide In ethanol; water at 50 - 55℃; for 1.5 - 2.5h;95%
C11H9ClN4
1228006-37-8

C11H9ClN4

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

C19H14F2N6OS
1228006-42-5

C19H14F2N6OS

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 1h;95%
C11H9ClN4O
1228006-39-0

C11H9ClN4O

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

C19H14F2N6O2S
1228006-44-7

C19H14F2N6O2S

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 1h;94%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine hydrochloride
86604-75-3

2-(chloromethyl)-4-methoxy-3,5-dimethylpyridine hydrochloride

pantoprazole sulfide
102625-64-9

pantoprazole sulfide

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 80℃; for 8h;94%
4-(chloromethyl)tetrazolo[1,5-a]quinoline
1228006-36-7

4-(chloromethyl)tetrazolo[1,5-a]quinoline

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

4-((5-(difluoromethoxy)-1H-benzo[d]imidazol-2-ylthio)methyl)tetrazolo[1,5-a]quinoline
1228006-41-4

4-((5-(difluoromethoxy)-1H-benzo[d]imidazol-2-ylthio)methyl)tetrazolo[1,5-a]quinoline

Conditions
ConditionsYield
With potassium carbonate In acetone at 20℃; for 1h;93%
4-(2,2,2-trifluoroethoxy)-2-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-3-methylpyridine

4-(2,2,2-trifluoroethoxy)-2-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-3-methylpyridine

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-(4-((4-(2,2,2-trifluoroethoxy)-3-methylpyridin-2-yl)methoxy)-3-methoxybenzylthio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

2-(4-((4-(2,2,2-trifluoroethoxy)-3-methylpyridin-2-yl)methoxy)-3-methoxybenzylthio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 20℃; for 15h;93%
4-chloro-2-chloromethyl-3-methoxypyridine hydrochloride
503058-51-3

4-chloro-2-chloromethyl-3-methoxypyridine hydrochloride

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

(5-difluoromethoxy)-2-[(4-chloro-3-methoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
368890-20-4

(5-difluoromethoxy)-2-[(4-chloro-3-methoxy-2-pyridinyl)methyl]thio-1H-benzimidazole

Conditions
ConditionsYield
With sodium hydroxide In water; toluene at 55 - 65℃; for 4 - 6h;92%
2-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-4-methoxy-3,5-dimethylpyridine

2-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-4-methoxy-3,5-dimethylpyridine

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-(4-((4-methoxy-3, 5-dimethylpyridin-2-yl)methoxy)-3-methoxybenzylthio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

2-(4-((4-methoxy-3, 5-dimethylpyridin-2-yl)methoxy)-3-methoxybenzylthio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 20℃; for 15h;92%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-1H-benzo[d]imidazole-2-d

5-(difluoromethoxy)-1H-benzo[d]imidazole-2-d

Conditions
ConditionsYield
With rose bengal; water-d2; oxygen; sodium chloride In N,N-dimethyl-formamide at 25℃; for 48h; Irradiation; Green chemistry;92%
para-diiodobenzene
624-38-4

para-diiodobenzene

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-2-[(4-iodophenyl)sulfanyl]-1H-benzimidazole
1312711-65-1

5-(difluoromethoxy)-2-[(4-iodophenyl)sulfanyl]-1H-benzimidazole

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In N,N-dimethyl-formamide at 140℃; for 24h;89%
2-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-3,4-dimethoxypyridine

2-((4-(chloromethyl)-2-methoxyphenoxy)methyl)-3,4-dimethoxypyridine

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-(4-((3,4-dimethoxypyridin-2-yl)methoxy)-3-methoxybenzylthio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

2-(4-((3,4-dimethoxypyridin-2-yl)methoxy)-3-methoxybenzylthio)-5-(difluoromethoxy)-1H-benzo[d]imidazole

Conditions
ConditionsYield
With tetrabutylammomium bromide; sodium hydroxide In dichloromethane; water at 20℃; for 15h;89%
7-methyl-1H-indole
933-67-5

7-methyl-1H-indole

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-(7-methyl-1H-indol-3-ylthio)-6-(difluoromethoxy)-1hbenzo[d]imidazole

2-(7-methyl-1H-indol-3-ylthio)-6-(difluoromethoxy)-1hbenzo[d]imidazole

Conditions
ConditionsYield
With manganese(III) triacetate dihydrate; acetic acid at 80℃; for 2h; Inert atmosphere; regioselective reaction;89%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

phenylacetylene
536-74-3

phenylacetylene

5-(difluoromethoxy)-2-(styrylthio)-1H-benzo[d]imidazole
1222462-01-2

5-(difluoromethoxy)-2-(styrylthio)-1H-benzo[d]imidazole

Conditions
ConditionsYield
Stage #1: 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole With sodium hydroxide In ethanol Heating;
Stage #2: phenylacetylene In ethanol Reflux; stereoselective reaction;
88%
para-iodoanisole
696-62-8

para-iodoanisole

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-2-[(4-methoxyphenyl)sulfanyl]-1H-benzimidazole
1312711-63-9

5-(difluoromethoxy)-2-[(4-methoxyphenyl)sulfanyl]-1H-benzimidazole

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In N,N-dimethyl-formamide at 140℃; for 24h;88%
1-tert-butyl-4-iodobenzene
35779-04-5

1-tert-butyl-4-iodobenzene

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-[(4-tert-butylphenyl)sulfanyl]-5-(difluoromethoxy)-1H-benzimidazole
1312711-64-0

2-[(4-tert-butylphenyl)sulfanyl]-5-(difluoromethoxy)-1H-benzimidazole

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In N,N-dimethyl-formamide at 140℃; for 24h;88%
indole
120-72-9

indole

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-(1H-indol-3-ylthio)-6-(difluoromethoxy)-1hbenzo[d]imidazole

2-(1H-indol-3-ylthio)-6-(difluoromethoxy)-1hbenzo[d]imidazole

Conditions
ConditionsYield
With manganese(III) triacetate dihydrate; acetic acid at 80℃; for 2h; Inert atmosphere; regioselective reaction;88%
2-(chloromethyl)-3,4-dimethoxypyridine
169905-10-6

2-(chloromethyl)-3,4-dimethoxypyridine

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

pantoprazole sulfide
102625-64-9

pantoprazole sulfide

Conditions
ConditionsYield
With sodium hydroxide In water; isopropyl alcohol at 20℃; for 3h;87.8%
With sodium hydroxide In water Flow reactor;
4-tolyl iodide
624-31-7

4-tolyl iodide

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-2-[(4-methylphenyl)sulfanyl]-1H-benzimidazole
1312711-62-8

5-(difluoromethoxy)-2-[(4-methylphenyl)sulfanyl]-1H-benzimidazole

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In N,N-dimethyl-formamide at 140℃; for 24h;87%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-1H-benzo[d]imidazole

5-(difluoromethoxy)-1H-benzo[d]imidazole

Conditions
ConditionsYield
With rose bengal; water; oxygen; sodium chloride In N,N-dimethyl-formamide at 25℃; for 48h; Irradiation; Green chemistry;87%
2-Iodothiophene
3437-95-4

2-Iodothiophene

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-2-(thiophen-2-ylsulfanyl)-1H-benzimidazole
1312711-70-8

5-(difluoromethoxy)-2-(thiophen-2-ylsulfanyl)-1H-benzimidazole

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In N,N-dimethyl-formamide at 140℃; for 22h;86%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

methyl iodide
74-88-4

methyl iodide

5-difluoromethoxy-2-methylthiobenzimidazole

5-difluoromethoxy-2-methylthiobenzimidazole

Conditions
ConditionsYield
With sodium hydroxide In methanol at 20℃; for 2h;84.3%
iodobenzene
591-50-4

iodobenzene

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

5-(difluoromethoxy)-2-(phenylsulfanyl)-1H-benzimidazole
1312711-61-7

5-(difluoromethoxy)-2-(phenylsulfanyl)-1H-benzimidazole

Conditions
ConditionsYield
With copper(l) iodide; 1,10-Phenanthroline; potassium carbonate In N,N-dimethyl-formamide at 140℃; for 22h;84%
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
97963-62-7

5-(difluoromethoxy)-2-mercapto-1H-benzimidazole

2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride
72830-09-2

2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride

pantoprazole sodium
138786-67-1

pantoprazole sodium

Conditions
ConditionsYield
Stage #1: 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole; 2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride With sodium hydroxide; tetrabutylammomium bromide In dichloromethane; water at 25 - 30℃; for 12h;
Stage #2: With sodium hydroxide; sodium hypochlorite In dichloromethane; water at 0 - 8℃; for 6h; Product distribution / selectivity;
83%
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