Shandong Mopai Biotechnology Co., LTD is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemicals. W
Cas:138786-67-1
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inquiryItems Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------
Cas:138786-67-1
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryJinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shangha
Cas:138786-67-1
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inquiryUnique advantages for Pantoprazole Sodium Cas138786-67-1 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White or off white crystalline powder Storage:-20°C Freezer Package:
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inquiryService we can provide: 1. Mixed container: We can mix different items in one container. 2. Quality control: Before shipment, we can provide free sample for test. Inspection before shipping. 3. Packing: We can pack according to your requirem
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryShanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu
Cas:138786-67-1
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inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem’s R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis
Cas:138786-67-1
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inquiryName:Pantoprazole Sodium CAS NO:138786-67-1 Grade:Medical scientific research and export Molecular formula:C16H14F2N3NaO4S Molecular weight:405.3516 Product Quality 12 years of chemical raw materials Mature operation of the industry System
Cas:138786-67-1
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inquiryOur company engages in Sodium Tripolyphosphate (STPP) and Sodium Hexametabphosphate (SHMP) production; development of noble metal catalysts, synthesis of electronic chemical materials and general chemicals Imp&Exp trading business. The company
Cas:138786-67-1
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inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:138786-67-1
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inquiry1. Product advantages ♦ High purity, all above 98.5%, no impurities after dissolution ♦ We will test each batch to ensure quality ♦ OEM and private brand services designed for free ♦ Various cap colors available ♦ W
Cas:138786-67-1
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:138786-67-1
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inquiryProduct Name Pantoprazole sodium CAS 138786-67-1 Molecular Formula C16H14F2N3NaO4S Molecular Weight
About Product Details Items Specifications Test Results Appearance White to white crystalline powde
Cas:138786-67-1
Min.Order:1 Gram
FOB Price: $1.0 / 2.0
Type:Lab/Research institutions
inquiry1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;
Cas:138786-67-1
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inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is
Cas:138786-67-1
Min.Order:10 Gram
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Type:Other
inquiryHanways chempharm is a specialized company concentrating on the R&D, production, marketing and technical service of APIs and pharmaceutical intermediates. The marketing department is located in Wuhan. We have two GMP facilities in Hubei Pr
Cas:138786-67-1
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Type:Trading Company
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:138786-67-1
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inquiryWe are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery
Cas:138786-67-1
Min.Order:10 Gram
FOB Price: $1.32
Type:Trading Company
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:138786-67-1
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inquiryPantoprazole Sodium CAS:138786-67-1 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic inte
Cas:138786-67-1
Min.Order:1 Gram
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inquiryWe have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful
Cas:138786-67-1
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:138786-67-1
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Hebei Mojin Biological Technology Co., Ltd. is specialize in the production of chemical raw materials and reagents,located in Shijiazhuang, Hebei Province. In recent decades, under the efforts of all staff, in Shandong, Henan, Guangdong and many othe
Cas:138786-67-1
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inquiryProduct Name: Pantoprazole Sodium Synonyms: 5-(difluoroMethoxy)-2-(((3,4-diMethoxypyridin-2-yl)Methyl)sulfinyl)-1H-benzo[d]iMidazole, sodiuM salt;1H-benziMidazole, 5-(difluoroMethoxy)-2-[[(3,4-diMethoxy-2-pyridinyl)Methyl]sulfinyl]-, sodiuM salt
Cas:138786-67-1
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiry5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
pantoprazole sodium
Conditions | Yield |
---|---|
With sodium hydroxide In water; acetonitrile at 20℃; | 95% |
With sodium hydroxide In ethanol for 5h; Reflux; | 95% |
With sodium hydroxide In water; ethyl acetate at 20℃; for 5.5h; | 92% |
pantoprazole sulfide
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: pantoprazole sulfide With sodium hydroxide; tert-butylhypochlorite In dichloromethane; water at 0 - 5℃; for 1h; Stage #2: With sodium hydroxide In water; acetone at 0 - 25℃; for 7h; | 95% |
Stage #1: pantoprazole sulfide With potassium tungstate dihydrate; dihydrogen peroxide at -5 - 0℃; for 4.5h; pH=3.5; Stage #2: With sodium hydroxide In water at 20℃; Temperature; Reagent/catalyst; | 78.7% |
With sodium hypochlorite; sodium hydroxide In methanol; water at -20 - -5℃; | |
Stage #1: pantoprazole sulfide With sodium hypochlorite; sodium hydroxide In water; acetonitrile at -5 - 30℃; Stage #2: With acetic acid In dichloromethane at 25 - 30℃; pH=8 - 8.5; Stage #3: With sodium hydroxide In dichloromethane; water at 25 - 30℃; Concentration; | |
Stage #1: pantoprazole sulfide With sodium hypochlorite; water; sodium hydroxide In ethyl acetate at 0 - 10℃; for 7h; Stage #2: With sodium thiosulfate In ethyl acetate for 0.333333h; |
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole; 2-Chloromethyl-3,4-dimethoxy-pyridine; hydrochloride With sodium hydroxide; tetrabutylammomium bromide In dichloromethane; water at 25 - 30℃; for 12h; Stage #2: With sodium hydroxide; sodium hypochlorite In dichloromethane; water at 0 - 8℃; for 6h; Product distribution / selectivity; | 83% |
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: 2-hydroxymethyl-3,4-dimethoxypyridine hydrochloride With thionyl chloride In dichloromethane at 0 - 15℃; for 1h; Stage #2: 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole With sodium hydroxide; tetrabutylammomium bromide In dichloromethane; water at 10 - 30℃; for 12h; pH=10 - 11; Stage #3: With sodium hydroxide; sodium hypochlorite In dichloromethane; water at 0 - 8℃; for 6h; Product distribution / selectivity; | 79.6% |
(5-difluoromethoxy)-2-[(4-chloro-3-methoxy-2-pyridinyl)methyl]thio-1H-benzimidazole
sodium methylate
pantoprazole sodium
Conditions | Yield |
---|---|
In methanol at 50℃; Heating / reflux; | 70.8% |
5-(difluoromethoxy)-2-[[(4-chloro-3-methoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole
pantoprazole sodium
Conditions | Yield |
---|---|
With sodium methylate In methanol at 50℃; Heating / reflux; | 70.8% |
pantoprazole sulfide
B
pantoprazole sodium
Conditions | Yield |
---|---|
With sodium hydroxide; sodium hypochlorite In water; ethyl acetate at -5℃; for 1 - 1.5h; Product distribution / selectivity; | A n/a B 65% C n/a |
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
pantoprazole sodium
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: sodium hydroxide / ethanol / 8 h / 80 °C 2: 3-chloro-benzenecarboperoxoic acid / chloroform / 4 h / 0 °C 3: sodium hydroxide / ethanol / 5 h / Reflux View Scheme | |
Multi-step reaction with 3 steps 1: sodium hydroxide / water; methanol / 3.5 h / 40 - 55 °C 2: LACTIC ACID; peracetic acid / methanol; dichloromethane / 1 h / -25 - -20 °C 3: sodium hydroxide / water; acetone / 40 - 45 °C View Scheme |
sodium hydroxide
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
pantoprazole sodium
Conditions | Yield |
---|---|
In water; acetonitrile at 25 - 35℃; for 1h; | |
In ethanol; dichloromethane; water at 20℃; pH=12.5; Product distribution / selectivity; |
5-(difluoromethoxy)-2-mercapto-1H-benzimidazole
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: 2-chloromethyl-3,4-dimethoxypyridine hydrochloride; 5-(difluoromethoxy)-2-mercapto-1H-benzimidazole With sodium hydroxide In ethanol; water at 35℃; for 2h; Stage #2: With sodium borate In ethanol at 45℃; for 2h; Stage #3: With dihydrogen peroxide In water at 20℃; for 2.5h; Concentration; Temperature; | 19.61 g |
pantoprazole sodium
Conditions | Yield |
---|---|
With zinc(II) chloride In water at 20℃; for 1.5h; | 95% |
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: pantoprazole sodium With sodium hydroxide In water at 25℃; for 1h; Stage #2: With magnesium chloride In water at 25℃; for 1h; | 94.6% |
pantoprazole sodium
zinc(II) chloride
Conditions | Yield |
---|---|
Stage #1: pantoprazole sodium With sodium hydroxide In water at 25℃; for 1h; Stage #2: zinc(II) chloride In water at 25℃; for 20h; | 94.2% |
(S)-1,1,2-triphenyl-1,2-ethanediol
pantoprazole sodium
Conditions | Yield |
---|---|
With acetic acid In ethanol for 0.5h; pH=7 - 8; Reflux; Industrial scale; | 94% |
pantoprazole sodium
Conditions | Yield |
---|---|
With water In tert-butyl methyl ether at 20 - 30℃; for 12h; Product distribution / selectivity; | 92.4% |
With water In di-isopropyl ether at 20 - 30℃; for 1 - 12h; Product distribution / selectivity; | 91.93% |
With water In diethyl ether at 20 - 30℃; for 12h; Product distribution / selectivity; | 91.93% |
With water at 0 - 35℃; Product distribution / selectivity; | 91.4% |
With water In dichloromethane at 25 - 35℃; for 1.5h; Product distribution / selectivity; |
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: pantoprazole sodium With sodium hydroxide In water at 25℃; for 1h; Stage #2: With calcium chloride In water at 25℃; for 20h; | 91.8% |
pantoprazole sodium
Conditions | Yield |
---|---|
With calcium chloride In water at 20℃; for 1.91667h; | 73% |
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: pantoprazole sodium With sodium hydroxide In water at 25℃; for 0.25h; Stage #2: With magnesium chloride In water at 25℃; for 2.5h; | 52.7% |
pantoprazole sodium
Conditions | Yield |
---|---|
With magnesium chloride In water at 20 - 30℃; for 21 - 22h; |
pantoprazole sodium
Conditions | Yield |
---|---|
With sodium hydroxide In ethanol for 24h; Heating / reflux; | |
In tert-butyl methyl ether; acetonitrile at 20℃; for 48h; | |
at 100℃; |
3-chlorosulfonylbenzoic acid 2-(toluene-4-sulfonyl)ethyl ester
pantoprazole sodium
B
3-[6-difluoromethoxy-2-{(3,4-dimethoxy-pyridin-2-yl)-methanesulfinyl}-benzimidazole-1-sulfonyl]benzoic acid 2-(toluene-4-sulfonyl)ethyl ester
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; triethylamine In dichloromethane at 20℃; for 1.5h; |
(4-chlorosulfonylphenoxy)acetic acid 2-(toluene-4-sulfonyl)ethyl ester
pantoprazole sodium
B
4-[6-difluoromethoxy-2-{(3,4-dimethoxypyridin-2-yl)methanesulfinyl}benzimidazole-1-sulfonyl]phenoxyacetic acid 2-(toluene-4-sulfonyl)ethyl ester
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; triethylamine In dichloromethane | |
With sodium hydrogencarbonate; triethylamine In dichloromethane Inert atmosphere; |
pantoprazole sodium
A
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)-chloromethyl]sulfinyl]-1H-benzimidazole
B
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)chlorohydroxymethyl]sulfinyl]-1H-benzimidazole
Conditions | Yield |
---|---|
With sodium hydroxide; sodium hypochlorite In water; acetonitrile at 20℃; for 12h; |
pantoprazole sodium
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridyl)methyl]sulfinyl]-1H-benzimidazole
Conditions | Yield |
---|---|
Stage #1: pantoprazole sodium With ethanol Stage #2: With water |
pantoprazole sodium
5-(difluoromethoxy)-2-[[(3,4-dimethoxy-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole sodium salt monohydrate
Conditions | Yield |
---|---|
In acetone Purification / work up; Heating / reflux; | |
With water In ethyl acetate; acetone at 0 - 55℃; for 2.25h; Product distribution / selectivity; | |
With water In ethyl acetate at 0 - 5℃; for 2h; Product distribution / selectivity; |
pantoprazole sodium
Conditions | Yield |
---|---|
With water In ethyl acetate; acetone at 0 - 55℃; for 2.25h; Product distribution / selectivity; | |
With water In ethyl acetate at 0 - 5℃; for 2h; Product distribution / selectivity; |
(4-chlorosulfonylphenoxy)acetic acid 2-(toluene-4-sulfonyl)ethyl ester
pantoprazole sodium
Conditions | Yield |
---|---|
Stage #1: (4-chlorosulfonylphenoxy)acetic acid 2-(toluene-4-sulfonyl)ethyl ester; pantoprazole sodium With sodium hydrogencarbonate; triethylamine In dichloromethane Inert atmosphere; Stage #2: With water; sodium hydrogencarbonate In acetonitrile at 65℃; for 5h; Inert atmosphere; |
Conditions | Yield |
---|---|
In water |
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