Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryWelcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our
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inquiryProduct: 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol [CAS:142569-70-8] Batch No: 110317-1 Manufacturing Date: Mar., 2011 Expiry Date: Mar., 2012 Analysis report number: 20110
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:142569-70-8
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inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi
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inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
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inquirychengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
Cas:142569-70-8
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inquiryName:2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS NO: 142569-70-8 Grade:Montelukast sodium intermediate (A5); montelukast pharmaceutical intermediate Product Quality 12 years of chemical raw materials
Cas:142569-70-8
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inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/601.html Product Name 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl) -3-
Cas:142569-70-8
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inquiry2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Basic information Product Name: 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol Synonyms: (s)-1-(3-(2-(7-chloro-2-quinolinyl
Cas:142569-70-8
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufactu
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Cas:142569-70-8
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inquiry1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd
Cas:142569-70-8
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inquiryName: (S)-1-(3-(2-(7-Chloro-2-Quinolinyl)Ethenyl)Phenyl)-3-(2-(1-Hydroxy-1-Methylethyl)-Phenyl)Propanol Molecular Formula:C29H28NO2Cl Molecular Weight:457.99 CAS No.:142569-70-8 Appearance:Similar White crystal Powder Appearance:Similar White
Cas:142569-70-8
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inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:Powder Storage:Store in sealed containers at cool & dry plac
Cas:142569-70-8
Min.Order:100 Gram
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:142569-70-8
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inquiryHangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac
Cas:142569-70-8
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inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:142569-70-8
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inquiry2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS:142569-70-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of
Cas:142569-70-8
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:142569-70-8
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inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
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inquiry2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol CAS: 142569-70-8 Specification Item Standard Identification A.H-NMR:Comply with the structure
Cas:142569-70-8
Min.Order:1 Kilogram
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Type:Other
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquirySpecification:USP/EP Month production ablity:50kg/Month Low price& High quality Manufacturer Appearance:white powder Storage:Room Temperature Application:142569-70-8
Cas:142569-70-8
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inquiryAppearance: Pale-Yellow Foam Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/C
Cas:142569-70-8
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inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
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Cas:142569-70-8
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inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
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inquiry(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
chlorophosphoric acid diphenyl ester
Conditions | Yield |
---|---|
With dmap; triethylamine In hexane; dichloromethane; ethyl acetate; toluene | 97.8% |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
phosphoric acid diphenyl ester chloride
Conditions | Yield |
---|---|
With dmap In toluene at 20℃; Reagent/catalyst; Solvent; | 92.6% |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
methanesulfonyl chloride
2-(2-(3(S)-(3-(2-(7-chloroquinolin-2-yl)ethyl)phenyl)-3-(methanesulfonyl-1-oxy)methylethyl)phenyl)-2-propanol
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In toluene; acetonitrile at -35 - -25℃; for 6.5h; | 81% |
With N-ethyl-N,N-diisopropylamine In toluene; acetonitrile at -35 - -25℃; for 6.5h; | 78.1% |
With N-ethyl-N,N-diisopropylamine In toluene; acetonitrile at -35 - -25℃; for 6.5h; | 78.1% |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
methanesulfonyl chloride
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In toluene; acetonitrile at -15 - 60℃; for 10.25h; |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
montelukast
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: N-ethyl-N,N-diisopropylamine / toluene; acetonitrile / 6.5 h / -35 - -25 °C 2.1: potassium tert-butylate; 3-ethyl-1-methyl-1H-imidazol-3-ium bromide / dimethyl sulfoxide / 0.5 h / 20 °C 2.2: 0.5 h 3.1: sodium hydroxide; water / tetrahydrofuran; methanol / 10 - 20 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: dmap; triethylamine / dichloromethane; ethyl acetate; toluene; hexane 2.1: 3-ethyl-1-methyl-1H-imidazol-3-ium bromide / dimethyl sulfoxide / 0.08 h / 10 °C 2.2: 0.17 h / 10 °C 2.3: 1 h / 15 - 17 °C View Scheme | |
Multi-step reaction with 3 steps 1.1: dmap; triethylamine / dichloromethane; ethyl acetate; toluene; hexane 2.1: potassium tert-butylate; 1-butyl-1-methylpyrrolidinium hexafluorophosphate / dimethyl sulfoxide / 0.5 h / 20 °C 2.2: 0.5 h 3.1: sodium hydroxide; water / tetrahydrofuran; methanol / 10 - 20 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / -25 °C / Inert atmosphere 2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -15 °C / Inert atmosphere 2.2: 7 h / -15 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 2 steps 1.1: N-ethyl-N,N-diisopropylamine / toluene; acetonitrile / 3 h / -35 - 50 °C / Inert atmosphere 2.1: sodium methylate / N,N-dimethyl-formamide; methanol / 1 h / -5 - 0 °C 2.2: -5 - 0 °C View Scheme |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
1-(((1(R)-(3-(2(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid methyl ester
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: N-ethyl-N,N-diisopropylamine / toluene; acetonitrile / 6.5 h / -35 - -25 °C 2.1: potassium tert-butylate; 3-ethyl-1-methyl-1H-imidazol-3-ium bromide / dimethyl sulfoxide / 0.5 h / 20 °C 2.2: 0.5 h View Scheme | |
Multi-step reaction with 2 steps 1.1: dmap; triethylamine / dichloromethane; ethyl acetate; toluene; hexane 2.1: potassium tert-butylate; 1-butyl-1-methylpyrrolidinium hexafluorophosphate / dimethyl sulfoxide / 0.5 h / 20 °C 2.2: 0.5 h View Scheme |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
dicyclohexylamine 1-(((1-(R)-(3-(2-(7-chloro-2-quinolidyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methyl-ethyl)phenyl)propyl)thio)methyl)cyclopropanyl acetate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: N-ethyl-N,N-diisopropylamine / toluene; acetonitrile / 6.5 h / -35 - -25 °C 2.1: n-butyllithium / hexane; tetrahydrofuran / 0.5 h / -15 °C 2.2: 9 h / -5 °C 2.3: 2 h View Scheme |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
Montelukast sodium
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / -25 °C / Inert atmosphere 2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -15 °C / Inert atmosphere 2.2: 7 h / -15 °C / Inert atmosphere 3.1: toluene / 20 - 80 °C 4.1: acetic acid / toluene; water / 0.33 h / 20 °C / pH 4 - 5 4.2: 0.5 h / 20 °C View Scheme | |
Multi-step reaction with 4 steps 1.1: N-ethyl-N,N-diisopropylamine / toluene; acetonitrile / 3 h / -35 - 50 °C / Inert atmosphere 2.1: sodium methylate / N,N-dimethyl-formamide; methanol / 1 h / -5 - 0 °C 2.2: -5 - 0 °C 3.1: ethyl acetate / 35 - 55 °C 4.1: sodium 2-ethylhexanoic acid / toluene / 30 - 35 °C / Inert atmosphere View Scheme | |
Multi-step reaction with 3 steps 1: dmap / toluene / 20 °C 2: sodium hydride / tetrahydrofuran / 0 - 20 °C 3: sodium hydroxide / methanol / 0.5 h / 20 °C / Inert atmosphere View Scheme |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: N-ethyl-N,N-diisopropylamine / tetrahydrofuran / 1 h / -25 °C / Inert atmosphere 2.1: sodium hexamethyldisilazane / tetrahydrofuran / 1 h / -15 °C / Inert atmosphere 2.2: 7 h / -15 °C / Inert atmosphere 3.1: toluene / 20 - 80 °C View Scheme |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: N-ethyl-N,N-diisopropylamine / toluene; acetonitrile / 3 h / -35 - 50 °C / Inert atmosphere 2.1: sodium methylate / N,N-dimethyl-formamide; methanol / 1 h / -5 - 0 °C 2.2: -5 - 0 °C 3.1: ethyl acetate / 35 - 55 °C View Scheme |
(S)-1-{3-[2-(7-chloroquinolin-2-yl)ethylene]-phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]-propan-1-ol
cyclopentyl 3-{2-methoxy-4-[(o-tolylsulfonyl)carbamoyl]benzyl}-1-methyl-1H-indol-5-ylcarbamate
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: dmap / toluene / 20 °C 2: sodium hydride / tetrahydrofuran / 0 - 20 °C View Scheme |
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