DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiryName: Montelukast Synonyms: Montelukas CAS:158966-92-8 MF: C35H36ClNO3S Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application: Pharmaceutical Intermediate Transportation:By sea or by air Po
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiryHangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det
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inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
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Montelukast Basic information Product Name: Montelukast Synonyms: (r-(e))-1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid;2-[1-[[(1r)-1-[3-[(e)-2-(7-chloroquinoli
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inquiryProduct name: Montelukast CAS No.:158966-92-8 Molecule Formula:C35H36ClNO3S Molecule Weight:586.18 Purity: 99.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Standard TESTING ITEMS
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inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
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inquiryHigh quality,stable supply chain.Appearance:white/off-white or light yellow Storage:Store in cool and dry place, keep away from strong light and heat. Package:aluminum bottle,glass bottle,PTFE bottle,cardboard drum Application:Active Pharmaceutical I
Conditions | Yield |
---|---|
Stage #1: 1-(mercaptomethyl)cyclopropane acetic acid disodium salt; C35H31ClNO5P With N-ethyl-N,N-diisopropylamine In tetrahydrofuran at -5 - 20℃; Inert atmosphere; Stage #2: With acetic acid In tetrahydrofuran at -5 - 0℃; pH=2 - 3; | 98.7% |
montelukast
Conditions | Yield |
---|---|
With acetic acid In dichloromethane; water for 0.25h; | 98.2% |
[R,E]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(methoxycarbonyl)phenyl]propyl]thio]methyl]-cyclopropane acetic acid
methylmagnesium chloride
montelukast
Conditions | Yield |
---|---|
With cerium chloride In tetrahydrofuran at -5 - 65℃; for 3.5h; Inert atmosphere; | 98% |
With cerium(III) chloride In tetrahydrofuran at -5 - 65℃; Product distribution / selectivity; Inert atmosphere; | 52.3% |
In tetrahydrofuran; toluene at 0 - 5℃; | |
Stage #1: With cerium(III) chloride In tetrahydrofuran at -65 - 20℃; for 3h; Heating / reflux; Stage #2: methylmagnesium chloride In tetrahydrofuran at -5 - 0℃; for 3h; Stage #3: [R,E]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(methoxycarbonyl)phenyl]propyl]thio]methyl]-cyclopropane acetic acid With water; acetic acid Product distribution / selectivity; more than 3 stages; | |
Stage #1: methylmagnesium chloride With cerium(III) chloride In tetrahydrofuran at -5 - 0℃; Inert atmosphere; Stage #2: [R,E]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(methoxycarbonyl)phenyl]propyl]thio]methyl]-cyclopropane acetic acid In tetrahydrofuran at -5 - 0℃; Inert atmosphere; |
(1-[(1(R)-(3-((E)-2-(7-chloroquinolin-2-yl)ethenyl)phenyl)-3-(2-(1-tetrahydropyran-2-yloxy-1-methylethyl)phenyl)propyl)thiomethyl]cyclopropyl)acetic acid adamantylamine salt
montelukast
Conditions | Yield |
---|---|
With hydrogenchloride In dichloromethane; water at 20℃; for 0.5h; | 98% |
With acetic acid Product distribution / selectivity; |
1-(((1-(R)-(3-(2-(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl) thio)methyl)cyclopropaneacetic acid dipropylamine salt
montelukast
Conditions | Yield |
---|---|
With acetic acid In water; isopropyl alcohol at 4 - 40℃; for 17h; Reagent/catalyst; Temperature; Solvent; Inert atmosphere; | 98% |
With acetic acid In dichloromethane; water at 25 - 35℃; Product distribution / selectivity; | 70.3% |
2-[1-(mercaptomethyl)cyclopropyl]acetic acid methyl ester
2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol
montelukast
Conditions | Yield |
---|---|
With dmap In N,N-dimethyl-formamide at 0 - 20℃; for 2.5h; Inert atmosphere; | 97.92% |
Stage #1: 2-[1-(mercaptomethyl)cyclopropyl]acetic acid methyl ester; 2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol With sodium methylate In dimethyl sulfoxide at -5 - 0℃; for 10h; Stage #2: With water; acetic acid at 10 - 20℃; pH=6.6; Product distribution / selectivity; | |
Stage #1: 2-[1-(mercaptomethyl)cyclopropyl]acetic acid methyl ester; 2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol With sodium hydroxide In ISOPROPYLAMIDE; water at -6 - 38℃; Stage #2: With tartaric acid In tetrahydrofuran; water pH=3 - 5; |
Montelukast sodium
montelukast
Conditions | Yield |
---|---|
With hydrogenchloride In water at 20 - 25℃; for 1h; | 97% |
With hydrogenchloride In water at 20℃; for 1h; pH=6; | 97.9% |
With hydrogenchloride; citric buffer In water; acetone at 20 - 25℃; for 2h; | 76% |
1-[[[(1R)-1-[3-[(1E)-2-(7-chloro-2-quinolinyl)ethenyl]phenyl]-3-[2-(1-hydroxy-1-methylethyl)phenyl]propyl]sulfanyl]methyl]cyclopropaneacetic acid L-(+)-α-phenylglycinol salt
montelukast
Conditions | Yield |
---|---|
With water; acetic acid In toluene at 35℃; for 0.5h; pH=< 6; Product distribution / selectivity; | 97% |
1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt
montelukast
Conditions | Yield |
---|---|
With acetic acid In water; isopropyl alcohol at 4 - 40℃; for 17h; Inert atmosphere; | 97% |
With acetic acid In water; toluene Product distribution / selectivity; | 86.39% |
With acetic acid In water; toluene Product distribution / selectivity; | 86.39% |
Conditions | Yield |
---|---|
Stage #1: methyl magnesium iodide With lanthanum(III) chloride; lithium chloride In toluene at 0℃; for 2h; Inert atmosphere; Stage #2: C39H34ClNO4S In tetrahydrofuran; toluene at 0℃; for 3h; Inert atmosphere; | 94% |
Conditions | Yield |
---|---|
Stage #1: 1-(sulfanylmethyl)cyclopropaneacetic acid With 3-ethyl-1-methyl-1H-imidazol-3-ium bromide In dimethyl sulfoxide at 10℃; for 0.0833333h; Stage #2: With potassium tert-butylate In dimethyl sulfoxide at 10℃; for 0.166667h; Stage #3: 2-(2-(3-(S)-(3-(2-(7-chloro-2-quinolinyl)-ethenyl)phenyl)-3-diphenylphosphatoxypropyl)phenyl)-2-propanol In dimethyl sulfoxide at 15 - 17℃; for 1h; Product distribution / selectivity; | 93% |
Conditions | Yield |
---|---|
Stage #1: methylmagnesium chloride With zinc(II) chloride In tetrahydrofuran; 2-methyl-propan-1-ol at 5℃; for 0.666667h; Inert atmosphere; Stage #2: C36H36ClNO4S In tetrahydrofuran for 4h; Inert atmosphere; | 92% |
2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl)acetonitrile
montelukast
Conditions | Yield |
---|---|
Stage #1: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl)acetonitrile With sodium hydroxide; ethanol; water for 15h; Heating / reflux; Stage #2: With acetic acid In ethanol; water; toluene Product distribution / selectivity; | 91% |
Stage #1: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl)acetonitrile With sodium hydroxide; ethanol; water for 30h; Heating / reflux; Stage #2: With water; acetic acid In toluene for 0.5h; pH=5.6; Product distribution / selectivity; | 86% |
Stage #1: 2-(1-((((R)-1-(3-((E)-2-(7-chloroquinolin-2-yl)vinyl)phenyl)-3-(2-(2-hydroxypropan-2-yl)phenyl)propyl)sulfanyl)methyl)cyclopropyl)acetonitrile With sodium hydroxide; water; tetrabutylammomium bromide In toluene at 120℃; for 168h; Stage #2: With acetic acid In water; toluene Product distribution / selectivity; | 83% |
1-(((1(R)-(3-(2(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid methyl ester
montelukast
Conditions | Yield |
---|---|
With water; sodium hydroxide In tetrahydrofuran; methanol at 10 - 20℃; Product distribution / selectivity; | 90.2% |
With methanol; sodium hydroxide In tetrahydrofuran for 5h; | 66% |
Stage #1: 1-(((1(R)-(3-(2(E)-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid methyl ester With methanol; sodium hydroxide; water In tetrahydrofuran at 0 - 20℃; for 48h; Stage #2: With water; ammonium chloride; acetic acid In tetrahydrofuran pH=5; Product distribution / selectivity; | 65.57% |
Conditions | Yield |
---|---|
at 10 - 20℃; for 10h; Concentration; | 90.2% |
C35H36ClNO3S*H3N
montelukast
Conditions | Yield |
---|---|
With acetic acid In water at 25 - 30℃; for 5 - 6h; Product distribution / selectivity; | 90% |
With toluene at 50 - 60℃; for 6h; Product distribution / selectivity; |
[R,E]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl) ethenyl]phenyl]-3-[2-(methylcarbonyl)phenyl] propyl]thio]methyl]cyclopropane acetic acid
methylmagnesium bromide
montelukast
Conditions | Yield |
---|---|
Stage #1: methylmagnesium bromide With lithium chloride In tetrahydrofuran at -10℃; for 0.5h; Inert atmosphere; Stage #2: [R,E]-1-[[[1-[3-[2-(7-chloro-2-quinolinyl) ethenyl]phenyl]-3-[2-(methylcarbonyl)phenyl] propyl]thio]methyl]cyclopropane acetic acid In tetrahydrofuran for 5h; Inert atmosphere; | 90% |
2-(2-(3-(S)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)-phenyl)-3-diphenylphosphate oxypropyl)phenyl)-2-propanol
montelukast
Conditions | Yield |
---|---|
Stage #1: 1-(mercaptomethyl)cyclopropanylacetic acid; 2-(2-(3-(S)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)-phenyl)-3-diphenylphosphate oxypropyl)phenyl)-2-propanol With sodium hydride In N,N-dimethyl-formamide at 0 - 20℃; for 18 - 20h; Stage #2: With ammonium chloride In water; N,N-dimethyl-formamide at 20℃; Product distribution / selectivity; | 87.1% |
(1-{1-(R)-(3-bromophenyl)-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid
7-chloro-2-ethenylquinoline
montelukast
Conditions | Yield |
---|---|
With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 100℃; for 4.25h; | 85% |
With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 100℃; for 4h; Product distribution / selectivity; Heck Reaction; | 67.6% |
Stage #1: (1-{1-(R)-(3-bromophenyl)-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid; 7-chloro-2-ethenylquinoline With triethylamine; palladium diacetate; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide at 100℃; for 4h; Stage #2: With water; citric acid In ethyl acetate; N,N-dimethyl-formamide; toluene pH=3 - 4; | |
Stage #1: (1-{1-(R)-(3-bromophenyl)-3-[2-(1-hydroxy-1-methyl-ethyl)-phenyl]-propylsulfanylmethyl}-cyclopropyl)-acetic acid; 7-chloro-2-ethenylquinoline; palladium diacetate; tris-(o-tolyl)phosphine In N,N-dimethyl-formamide for 0.25h; Stage #2: With triethylamine In N,N-dimethyl-formamide at 100℃; for 4h; Stage #3: With citric acid In water; ethyl acetate; N,N-dimethyl-formamide; toluene pH=3 - 4; |
C6H8N2*C35H36ClNO3S
montelukast
Conditions | Yield |
---|---|
With acetic acid In toluene at 25 - 30℃; for 12 - 14h; | 85% |
Conditions | Yield |
---|---|
In toluene at -10 - -5℃; for 5h; Inert atmosphere; | 85% |
1-(((1-(R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-((1-tetrahydropyranyloxy)-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropyl acetate
montelukast
Conditions | Yield |
---|---|
Stage #1: 1-(((1-(R)-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-((1-tetrahydropyranyloxy)-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropyl acetate With pyridine; toluene-4-sulfonic acid In methanol at 60℃; for 8h; Stage #2: With sodium hydroxide In methanol at 30℃; for 2h; | 84.9% |
2-[1-(mercaptomethyl)cyclopropyl]acetic acid methyl ester
2-(2-(3(S)-(3-(2-(7-chloroquinolin-2-yl)ethyl)phenyl)-3-(methanesulfonyl-1-oxy)methylethyl)phenyl)-2-propanol
montelukast
Conditions | Yield |
---|---|
Stage #1: 2-[1-(mercaptomethyl)cyclopropyl]acetic acid methyl ester With sodium hexamethyldisilazane In tetrahydrofuran at -15℃; for 1h; Inert atmosphere; Stage #2: 2-(2-(3(S)-(3-(2-(7-chloroquinolin-2-yl)ethyl)phenyl)-3-(methanesulfonyl-1-oxy)methylethyl)phenyl)-2-propanol In tetrahydrofuran at -15℃; for 7h; Product distribution / selectivity; Inert atmosphere; | 84.7% |
1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid benzylamine salt
montelukast
Conditions | Yield |
---|---|
With acetic acid In toluene at 25 - 30℃; for 12 - 14h; | 81% |
montelukast
Conditions | Yield |
---|---|
Stage #1: methylmagnesium chloride With cerium(III) chloride In tetrahydrofuran at 0 - 5℃; for 1.16667h; Stage #2: C34H32ClNO4S*ClH In tetrahydrofuran at 10℃; for 0.166667h; Stage #3: With water; sodium acetate; acetic acid In tetrahydrofuran Product distribution / selectivity; | 80% |
Conditions | Yield |
---|---|
Stage #1: methylmagnesium chloride; cerium(III) chloride In tetrahydrofuran at 0 - 5℃; for 1.16667h; Stage #2: C34H32ClNO4S*ClH In tetrahydrofuran at 10℃; for 0.166667h; | 80% |
1-(mercaptomethyl)-cyclopropaneacetic acid
2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol
montelukast
Conditions | Yield |
---|---|
Stage #1: 1-(mercaptomethyl)-cyclopropaneacetic acid; 2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol With sodium hydroxide In N,N-dimethyl-formamide at -5 - 0℃; for 6h; Stage #2: With water; sodium chloride In Isopropyl acetate; N,N-dimethyl-formamide for 0.5h; Stage #3: With tartaric acid In water Product distribution / selectivity; | 71.1% |
Stage #1: 1-(mercaptomethyl)-cyclopropaneacetic acid; 2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol With sodium hydroxide In N,N-dimethyl-formamide at -5 - 0℃; for 6h; Stage #2: With water; sodium chloride In Isopropyl acetate; N,N-dimethyl-formamide for 0.583333h; Stage #3: With tartaric acid In Isopropyl acetate; water at 0 - 20℃; for 4.25h; pH=4 - 5; Product distribution / selectivity; | 42.54% |
Stage #1: 1-(mercaptomethyl)-cyclopropaneacetic acid; 2-[2-[3(S)-[3-[(1E)-2-(7-chloroquinoline-2-yl)ethenyl]phenyl]-3-methanesulfonyloxypropyl]phenyl]-2-propanol With sodium hydroxide In N,N-dimethyl-formamide at -5 - 0℃; for 6h; Stage #2: With water; sodium chloride In Isopropyl acetate; N,N-dimethyl-formamide for 0.75h; Stage #3: With pyrographite; tartaric acid Product distribution / selectivity; more than 3 stages; |
montelukast isopropylamine salt
montelukast
Conditions | Yield |
---|---|
With acetic acid In dichloromethane; water at 25 - 35℃; for 0.5h; | 70.3% |
With acetic acid In dichloromethane; water at 25 - 35℃; for 0.5h; pH=4.5; | 70.3% |
With acetic acid In dichloromethane; water for 0.166667h; pH=4.0 - 4.5; Product distribution / selectivity; |
1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid α-methylbenzylamine salt
montelukast
Conditions | Yield |
---|---|
With acetic acid In dichloromethane; water at 20 - 25℃; Product distribution / selectivity; Heating / reflux; | 70.3% |
Conditions | Yield |
---|---|
In methanol; toluene at 20℃; for 1h; Product distribution / selectivity; | 100% |
In methanol; toluene at 2 - 20℃; for 0.75h; Product distribution / selectivity; | 100% |
In methanol at 20℃; for 1h; Product distribution / selectivity; | 73% |
In methanol at 25 - 35℃; for 0.166667h; |
montelukast
Montelukast sodium
Conditions | Yield |
---|---|
With sodium hydroxide In methanol; toluene at 20℃; for 1h; | 100% |
With sodium hydroxide In methanol; water; toluene for 0.5h; Product distribution / selectivity; Alkaline aqueous solution; | 98% |
With sodium hydroxide In methanol at -5 - 35℃; for 1h; | 98.7% |
montelukast
C35H36ClNO3S*H3N
Conditions | Yield |
---|---|
With ammonia In ethyl acetate at 20 - 25℃; for 1h; | 97% |
Conditions | Yield |
---|---|
In acetonitrile at 25℃; for 1h; Heating / reflux; | 95% |
cycloheptanamine
montelukast
(R-(E))-1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid cycloheptylammonium salt
Conditions | Yield |
---|---|
In ethyl acetate at 25 - 60℃; for 1h; | 95% |
In ethyl acetate | 65% |
In ethyl acetate at 25℃; Product distribution / selectivity; | |
In ethyl acetate at 20℃; |
Conditions | Yield |
---|---|
In cyclohexane; toluene at 25℃; for 1h; Heating / reflux; | 95% |
benzylamine
montelukast
1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid benzylamine salt
Conditions | Yield |
---|---|
In ethyl acetate at 20 - 25℃; for 1h; | 95% |
In n-heptane; ethyl acetate at 20 - 25℃; for 50h; | |
In ethyl acetate at 20℃; for 24h; |
Conditions | Yield |
---|---|
In n-heptane; toluene; acetonitrile | 95% |
2-aminobutanol
montelukast
Conditions | Yield |
---|---|
In ethyl acetate at 15 - 25℃; for 5h; Time; Solvent; Temperature; | 95% |
cyclooctylamine
montelukast
(R-(E))-1-(((1-(3-(2-(7-chloro-2-quinolinyl)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropaneacetic acid cyclooctylammonium salt
Conditions | Yield |
---|---|
In toluene at 25℃; for 1h; Heating / reflux; | 94% |
In ethyl acetate Product distribution / selectivity; | 70% |
In water; toluene for 1.5h; Product distribution / selectivity; | 70% |
N-cyclohexyl-cyclohexanamine
montelukast
1-(((1(R)-(3-(2-(7-chloro-2-quinolinil)ethenyl)phenyl)-3-(2-(1-hydroxy-1-methylethyl)phenyl)propyl)thio)methyl)cyclopropane acetic acid dicyclohexylamine salt
Conditions | Yield |
---|---|
In n-heptane; toluene Product distribution / selectivity; | 90% |
In ethyl acetate; toluene Product distribution / selectivity; | 61% |
In toluene at 20 - 25℃; for 0.25h; Product distribution / selectivity; | 59.67% |
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