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142569-70-8 Montelukast leukotriene C29H28ClNO2
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Pharmaceutical Intermediate Montelukast leukotriene D4 CAS142569-70-8
Product info :
Name: 2-(2-(3-(2-(7-Chloro-2-quinolinyl)-ethenylphenyl)-3-hydroxypropyl)phenyl)-2-propanol
Molecular Formula: C29H28ClNO2
Formula Weight: 457.99
CAS No.: 142569-70-8
Application : Usage An intermediate of Montelukast
About Montelukast :
Montelukast selectively antagonizes leukotriene D 4 (LTD4) by binding to it so that block the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1.
Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of asthma and to relieve symptoms of seasonal allergies. Montelukast blocks the action of leukotriene D4 on the cysteinyl leukotriene receptor CysLT1 in the lungs and bronchial tubes by binding to it, preventing airway edema, smooth muscle contraction, and enhanced secretion of thick, viscous mucus. This reduces the bronchoconstriction otherwise caused by the leukotriene, and results in less inflammation.
Chemical Properties
Molecular Structure | |
Molecular Weight | 457.99 |
Density | 1.244g/cm3 |
Boiling Point | 636.8°Cat760mmHg |
Flash Point | 338.9 |
Refractive index | 1.686 |
Safety Information
Hazard Codes | Xi,N,C |
Risk Statements | 21/22-34-43-51/53 |
Safety Statements | 22-26-36/37/39-45-61 |
Hazard Note |
Irritant/Stench |
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