Anti-Inflammatory API Naproxen Sodium Powder Cas 26159-34-2

 

Anti-Inflammatory API Naproxen Sodium Powder Cas 26159-34-2

 

Quick Details 
 Prodcut name: Naproxen sodium
Specification: 99%
Appearance: White Powder 

CAS: 26159-34-2
Mesh size: 80 Mesh
Grade: Pharmaceutical
Brand Name: PRIUS
Test Method: HPLC

 

Description 

Naproxen sodium is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class that relieves pain, fever, swelling, and stiffness.[6][7] It is a nonselective COX inhibitor, usually sold as the sodium salt. It is available in both an immediate release and extended release formulation. Naproxen is generally safe for use by breastfeeding mothers.

Application

 

Naproxen sodium is non-steroidal anti-inflammatory drug. It is suitable for relieving all kinds of mild to moderate pain,such as tooth extraction and other post-operative pain, primary dysmenorrhea and headache. Naproxen sodium can also be used to treat rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, Juvenilearthritis, tendinitis, bursitis and acute gouty arthritis. Naproxen sodium can relieve symptoms of swelling and limited activity in arthritis.

1.Relieve low to medium-grade pain, e.g. from tooth extraction, surgery, functional dysmenorrhea or headache. 2.Applicable for rheumatoid arthritis, bone arthritis, ankylosing spondylitis, juvenile arthritis, myotenositis, bursitis and acute gouty arthritis. It is also helpful for relieve pain, swelling and movement limitation caused by arthritis. Comparing with aspirin and indomethacin, the effect is similar, but its rate and severity of causing adverse effect in the gastrointestinal tract and nervous system are both lower.

COA 


 

Item		Specifications	Results
Appearance		White to almost white  crystalline powder	Almost white crystalline
Identification	A. Infrared absorption	The infrared absorption  spectrum is concordant  with the reference spectrum	Conform
	B. Ultraviolet Absorption	Absorptivities at 272nm, calculated on the dried  base, do not differ by  more than 3%	<1%
Specific rotation		-17.0°to -15.3°	-16.7°
Loss on drying		≤1.0%	0.2%
Heavy metals		≤0.002%	<0.002%
Free Naproxen		≤1.0%	0.1%
Related substances  (HPLC)	Impurity D(in-house)	≤0.10%	<0.01%
	Impurity E(in-house, Impurity C in EP)	≤0.10%	<0.01%
	Any other impurity	≤0.10%	<0.01%
	Total impurities	≤0.5%	<0.01%
Residual Solvents	Toluene	≤50ppm	<1ppm
	Methanol	≤50ppm	<12ppm
	Ethanol	≤100ppm	<8ppm
[Assay]  (On the dried basis) It contains C14H13NaO3	98.5% to 101.5%		99.7%