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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities

Vitamin D2 Manufacturer/High quality/Best price/In stock

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Our advantage--we provide High quality Vitamin D2-Ergocalciferol and competitive price. (1) 28 year experience in pharmaceutical industry (2)ISO9001:2008 certificated company (3)Fischer Chemicals AG China office Basic information of Vit

Vitamin D2/Ergocalciferol CAS No.: 50-14-6

Cas:50-14-6

Min.Order:100 Gram

Negotiable

Type:Trading Company

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Vitamin D2 supplier in China

Cas:50-14-6

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

CAS No.: 50-14-6 Other Names: cholecalciferol MF: C28H44O EINECS No.: 200-014-9 Place of Origin: Henan, China (Mainland) Type: Vitamins, Amino Acids and Coen

High quality injection grade Vitamin D2 powder with best price

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $40.0 / 50.0

Type:Other

inquiry

Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

ERGOCALCIFEROL (VITAMIN D2) 50-14-6 vitamin D2

Cas:50-14-6

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Vitamin D2 Cas 50-14-6 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White Powder Storage:2-8°C Package:1kg/foil bag, 25kg/drum or as you

Factory price top quality Vitamin D2 Cas 50-14-6 with high purity

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $80.0

Type:Trading Company

inquiry

Hefei TNJ chemical industry co.,ltd

1, Full experience of large numbers containers loading in main Chinese seaports 2, Packing with pallet as buyer's special request 3, Best service after shipment with e-mail 4, Cargoes together with container sales service available

Vitamin D2 50-14-6

Cas:50-14-6

Min.Order:2 Metric Ton

Negotiable

Type:Trading Company

inquiry

Hangzhou Think Chemical Co. Ltd

Ergocalciferol (Vitamin D2)[CAS.No:50-14-6] Complies with USP/BP 2.5 Kg/Tin , 2 Tin/Carton HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about

Vitamin D2 / Ergocalciferol USP/BP

Cas:50-14-6

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Vitamin D2

Cas:50-14-6

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Vitamin D2 50-14-6 ISO Producer

Cas:50-14-6

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chengdu Lemeitian Pharmaceutical Technology Co,. Ltd

ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,

vitamin D2

Cas:50-14-6

Min.Order:10 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

Vitamin D2

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Vitamin D2

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Vitamin D2

Cas:50-14-6

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Vitamin D2

Cas:50-14-6

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

Vitamin D2

Cas:50-14-6

Min.Order:1 Metric Ton

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Henan Tianfu Chemical Co., Ltd.

Vitamin D2 Basic information Vitamin D Toxicity Limited use The maximum allowable amount as food additives and maximal allowable residue limits Chemical Properties Application Production method Product

TIANFU-CHEM CAS:50-14-6 Vitamin D2

Cas:50-14-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Vitamin D2 cas 50-14-6

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $48.0 / 58.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 50-14-6 with best quality

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

High quality Ergocalciferol Vitamin D2 CAS 50-14-6

Cas:50-14-6

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Name: Vitamin D2 Synonyms: (3beta)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol CAS:50-14-6 MF: C28H44O Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application:Supplement Transportation:By

Vitamin D2

Cas:50-14-6

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White powder Storage:Store in sealed containers at cool & dr

Vitamin D2 CAS:50-14-6 Promote absorption of calcium

Cas:50-14-6

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Vitamin D2 50-14-6

Cas:50-14-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Shanghai Minstar Chemical Co., Ltd

Product Name: Vitamin D2 CAS: 50-14-6 MF: C28H44O MW: 396.65 EINECS: 200-014-9 Mol File: 50-14-6.mol Vitamin D2 Structure Vitamin D2 Chemical Properties Melting point 114-118 °C(lit.) alpha 82 º (c=3, in acetone 2

Vitamin D2

Cas:50-14-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present

Vitamin D2

Cas:50-14-6

Min.Order:1 Gram

FOB Price: $20.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Vitamin D2 CAS:50-14-6 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediates, s

Vitamin D2 CAS:50-14-6

Cas:50-14-6

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Vitamin D2

Cas:50-14-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Changchun Artel lmport and Export trade company

Superiority We can customize and synthesize products that other suppliers may not be able to provide. Advantage cof, mof ligand manufacturer Product Detail adrenochrome semicarbazone The common name of c

wholesale 99% Vitamin D2 CAS:50-14-6

Cas:50-14-6

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

Vitamin D2 CAS50-14-6

Cas:50-14-6

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

(3S,5Z,7E)-3-(3,5-dinitro-benzoyloxy)-9,10-seco-ergosta-5,7,10(19),22t-tetraene
4712-11-2

(3S,5Z,7E)-3-(3,5-dinitro-benzoyloxy)-9,10-seco-ergosta-5,7,10(19),22t-tetraene

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
With sodium hydroxide In ethanol at 20℃; for 0.75h; Inert atmosphere;91%
Ergosterol
57-87-4

Ergosterol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Stage #1: Ergosterol In 1,4-dioxane Irradiation;
Stage #2: at 100℃;
23%
With diethyl ether Irradiation.mit UV-Licht (durch aethanol. Xylol-Loesung gefiltert);
Einwirkung elektrischer Entladungen;
diethyl ether
60-29-7

diethyl ether

Ergosterol
57-87-4

Ergosterol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
diethyl ether
60-29-7

diethyl ether

Ergosterol
57-87-4

Ergosterol

A

Calciferol
50-14-6

Calciferol

B

lumisterol
474-69-1

lumisterol

C

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
diethyl ether
60-29-7

diethyl ether

Ergosterol
57-87-4

Ergosterol

A

Calciferol
50-14-6

Calciferol

B

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
diethyl ether
60-29-7

diethyl ether

lumisterol
474-69-1

lumisterol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
UV-Licht.Irradiation;
UV-Licht.Irradiation;
diethyl ether
60-29-7

diethyl ether

tachysterol
115-61-7

tachysterol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
at 20℃; UV-Licht.Irradiation;
previtamin D2
21307-05-1

previtamin D2

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
With benzene at 60℃; Lichtausschluss;
Multi-step reaction with 2 steps
2: diethyl ether / Irradiation.mit UV-Licht (Magnesium-Funken)
View Scheme
3β-hydroxy-9,10-secoergosta-5(E),7(E),10(19),22(E)-tetraene
51744-66-2

3β-hydroxy-9,10-secoergosta-5(E),7(E),10(19),22(E)-tetraene

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Irradiation.UV-Licht <λ: >290 nm>;
lumisterol
474-69-1

lumisterol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
With diethyl ether Irradiation.mit UV-Licht (Magnesium-Funken);
With diethyl ether Irradiation.mit UV-Licht (Magnesium-Funken);
lumisterol
474-69-1

lumisterol

A

Calciferol
50-14-6

Calciferol

B

tachysterol
115-61-7

tachysterol

ethanol
64-17-5

ethanol

Ergosterol
57-87-4

Ergosterol

benzene
71-43-2

benzene

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
ethanol
64-17-5

ethanol

Ergosterol
57-87-4

Ergosterol

benzene
71-43-2

benzene

A

Calciferol
50-14-6

Calciferol

B

lumisterol
474-69-1

lumisterol

C

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
ethanol
64-17-5

ethanol

Ergosterol
57-87-4

Ergosterol

benzene
71-43-2

benzene

A

Calciferol
50-14-6

Calciferol

B

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
Ergosterol
57-87-4

Ergosterol

benzene
71-43-2

benzene

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
Ergosterol
57-87-4

Ergosterol

benzene
71-43-2

benzene

A

Calciferol
50-14-6

Calciferol

B

lumisterol
474-69-1

lumisterol

C

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
Ergosterol
57-87-4

Ergosterol

benzene
71-43-2

benzene

A

Calciferol
50-14-6

Calciferol

B

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
mit UV-Licht unter Kuehlung bei Luftausschluss.Irradiation;
previtamin D2
21307-05-1

previtamin D2

benzene
71-43-2

benzene

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
at 60℃; Lichtausschluss;
at 40 - 70℃; Rate constant; Isomerisierung;
3β-hydroxy-9,10-secoergosta-5(E),7(E),10(19),22(E)-tetraene
51744-66-2

3β-hydroxy-9,10-secoergosta-5(E),7(E),10(19),22(E)-tetraene

benzene
71-43-2

benzene

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Isomerisierung; UV-Licht (λ: >290 nm).Irradiation;
Ergosterol
57-87-4

Ergosterol

A

Calciferol
50-14-6

Calciferol

B

previtamin D2
21307-05-1

previtamin D2

C

lumisterol
474-69-1

lumisterol

D

tachysterol
115-61-7

tachysterol

Conditions
ConditionsYield
With var. irradiation time; the influence of sunlamp emission spectrum on the course of the reaction In ethanol Product distribution; Irradiation;
tert-Butyl-dimethyl-{(S)-4-methylene-3-[2-[(1R,3aS,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexyloxy}-silane

tert-Butyl-dimethyl-{(S)-4-methylene-3-[2-[(1R,3aS,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexyloxy}-silane

A

Calciferol
50-14-6

Calciferol

B

(7Z)-Vitamin D2
247900-07-8

(7Z)-Vitamin D2

Conditions
ConditionsYield
With tetrabutyl ammonium fluoride In tetrahydrofuran at 20℃; desilylation; overnight;
O-(3.5-dinitro-benzoyl)-ergocalciferol
4712-11-2, 116572-06-6, 124564-78-9

O-(3.5-dinitro-benzoyl)-ergocalciferol

ethanolic KOH-solution

ethanolic KOH-solution

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
unter Stickstoff;
O-(3.5-dinitro-benzoyl)-ergocalciferol
4712-11-2, 116572-06-6, 124564-78-9

O-(3.5-dinitro-benzoyl)-ergocalciferol

methanol. KOH-solution

methanol. KOH-solution

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
unter Stickstoff;
O-(Naphthoyl-(2))-ergocalciferol

O-(Naphthoyl-(2))-ergocalciferol

methylammonium carbonate
15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

methanol. KOH-solution

methanol. KOH-solution

Calciferol
50-14-6

Calciferol

(1R,3aR,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-one
55812-80-1, 55870-05-8, 70144-73-9

(1R,3aR,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-one

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Multi-step reaction with 5 steps
1.1: 81 percent / Amberlite<*> IR-118 ion-exchange resin; Na; EtOH / diethyl ether / 2.5 h / 0 °C
2.1: 72 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran / 25 h / 0 - 20 °C
3.1: 73 percent / H2O2 / (NH4)6Mo7O24*4H2O / aq. ethanol / 240 h / 20 °C
4.1: NaHMDS / diethyl ether; tetrahydrofuran / 1 h / -78 °C
4.2: Dess-Martin periodinane / CH2Cl2 / 0.5 h / 20 °C
4.3: diethyl ether; tetrahydrofuran / -100 - 20 °C
5.1: Bu4NF*3H2O / tetrahydrofuran / 20 °C / overnight
View Scheme
(2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol
96685-53-9

(2Z)-2-<(5S)-5-(tert-butyldimethylsilyloxy)-2-methylene-cyclohexylidene>-ethanol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: NaHMDS / diethyl ether; tetrahydrofuran / 1 h / -78 °C
1.2: Dess-Martin periodinane / CH2Cl2 / 0.5 h / 20 °C
1.3: diethyl ether; tetrahydrofuran / -100 - 20 °C
2.1: Bu4NF*3H2O / tetrahydrofuran / 20 °C / overnight
View Scheme
(4R,7aR)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-4-((R,Z)-1-hydroxy-2-((S)-5-hydroxy-2-methylenecyclohexylidene)ethyl)-7a-methyloctahydro-1H-inden-4-ol
84985-78-4

(4R,7aR)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-4-((R,Z)-1-hydroxy-2-((S)-5-hydroxy-2-methylenecyclohexylidene)ethyl)-7a-methyloctahydro-1H-inden-4-ol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Multi-step reaction with 7 steps
1.1: 89 percent / imidazole; DMAP / CH2Cl2 / 20 °C
2.1: pyridine; Pb(OAc)4 / CH2Cl2 / 0.25 h / 0 °C
2.2: 83 percent / CeCl3*7H2O; NaBH4 / methanol / 0.25 h / 0 °C
3.1: 81 percent / Amberlite<*> IR-118 ion-exchange resin; Na; EtOH / diethyl ether / 2.5 h / 0 °C
4.1: 72 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran / 25 h / 0 - 20 °C
5.1: 73 percent / H2O2 / (NH4)6Mo7O24*4H2O / aq. ethanol / 240 h / 20 °C
6.1: NaHMDS / diethyl ether; tetrahydrofuran / 1 h / -78 °C
6.2: Dess-Martin periodinane / CH2Cl2 / 0.5 h / 20 °C
6.3: diethyl ether; tetrahydrofuran / -100 - 20 °C
7.1: Bu4NF*3H2O / tetrahydrofuran / 20 °C / overnight
View Scheme
Multi-step reaction with 4 steps
1.1: 89 percent / imidazole; DMAP / CH2Cl2 / 20 °C
2.1: pyridine; Pb(OAc)4 / CH2Cl2 / 0.25 h / 0 °C
2.2: 81 percent / CeCl3*7H2O; NaBH4 / methanol / 0.25 h / 0 °C
3.1: NaHMDS / diethyl ether; tetrahydrofuran / 1 h / -78 °C
3.2: Dess-Martin periodinane / CH2Cl2 / 0.5 h / 20 °C
3.3: diethyl ether; tetrahydrofuran / -100 - 20 °C
4.1: Bu4NF*3H2O / tetrahydrofuran / 20 °C / overnight
View Scheme
(5Z,22E)-(7R)-3β-(tert-butyldimethylsilyloxy)-9,10-seco-8α-ergosta-5,10(19),22-triene-7,8-diol
131852-63-6

(5Z,22E)-(7R)-3β-(tert-butyldimethylsilyloxy)-9,10-seco-8α-ergosta-5,10(19),22-triene-7,8-diol

Calciferol
50-14-6

Calciferol

Conditions
ConditionsYield
Multi-step reaction with 6 steps
1.1: pyridine; Pb(OAc)4 / CH2Cl2 / 0.25 h / 0 °C
1.2: 83 percent / CeCl3*7H2O; NaBH4 / methanol / 0.25 h / 0 °C
2.1: 81 percent / Amberlite<*> IR-118 ion-exchange resin; Na; EtOH / diethyl ether / 2.5 h / 0 °C
3.1: 72 percent / PPh3; diisopropyl azodicarboxylate / tetrahydrofuran / 25 h / 0 - 20 °C
4.1: 73 percent / H2O2 / (NH4)6Mo7O24*4H2O / aq. ethanol / 240 h / 20 °C
5.1: NaHMDS / diethyl ether; tetrahydrofuran / 1 h / -78 °C
5.2: Dess-Martin periodinane / CH2Cl2 / 0.5 h / 20 °C
5.3: diethyl ether; tetrahydrofuran / -100 - 20 °C
6.1: Bu4NF*3H2O / tetrahydrofuran / 20 °C / overnight
View Scheme
Multi-step reaction with 3 steps
1.1: pyridine; Pb(OAc)4 / CH2Cl2 / 0.25 h / 0 °C
1.2: 81 percent / CeCl3*7H2O; NaBH4 / methanol / 0.25 h / 0 °C
2.1: NaHMDS / diethyl ether; tetrahydrofuran / 1 h / -78 °C
2.2: Dess-Martin periodinane / CH2Cl2 / 0.5 h / 20 °C
2.3: diethyl ether; tetrahydrofuran / -100 - 20 °C
3.1: Bu4NF*3H2O / tetrahydrofuran / 20 °C / overnight
View Scheme
Calciferol
50-14-6

Calciferol

(S)-3-[(1R,3aS,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ6-benzo[c]thiophen-5-ol
87680-65-7

(S)-3-[(1R,3aS,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidenemethyl]-2,2-dioxo-2,3,4,5,6,7-hexahydro-1H-2λ6-benzo[c]thiophen-5-ol

Conditions
ConditionsYield
With sulfur dioxide 1.) reflux, 30 min, 2.) RT, 30 min;100%
With sulfur dioxide In water; benzene for 3.5h;
With sulfur dioxide In dichloromethane at -10℃; for 1.25h;
Calciferol
50-14-6

Calciferol

(8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol
64190-52-9

(8S,20S)-de-A,B-20-(hydroxymethyl)pregnan-8-ol

Conditions
ConditionsYield
Stage #1: Calciferol With ozone In methanol; dichloromethane at -78℃; for 3h; Inert atmosphere;
Stage #2: With sodium tetrahydroborate In methanol; dichloromethane at -78 - 20℃; for 0.5h; Inert atmosphere;
99%
Stage #1: Calciferol With ozone In dichloromethane at -78℃;
Stage #2: With sodium tetrahydroborate In methanol at 0℃;
90%
Stage #1: Calciferol With pyridine; ozone In methanol at -78℃; Inert atmosphere;
Stage #2: With methanol; sodium tetrahydroborate at 20℃;
81%
Calciferol
50-14-6

Calciferol

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

vitamin D2 tosylate
72204-99-0

vitamin D2 tosylate

Conditions
ConditionsYield
With pyridine99%
With triethylamine In dichloromethane at -5 - 20℃;89.4%
With pyridine at 20 - 22℃; for 22h;
Calciferol
50-14-6

Calciferol

C28H46O3S

C28H46O3S

Conditions
ConditionsYield
With sulfur dioxide In dichloromethane at -20 - -10℃; Inert atmosphere;95.7%
Calciferol
50-14-6

Calciferol

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

3(S)-tert-butyldimethylsilyloxy-9,10-secoergosta-5,7(E),10(19),22(E)-tetraene
104846-62-0

3(S)-tert-butyldimethylsilyloxy-9,10-secoergosta-5,7(E),10(19),22(E)-tetraene

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide for 2.5h;95%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1h;92%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 1h;92%
poly(methacrylic acid)
79-41-4

poly(methacrylic acid)

Calciferol
50-14-6

Calciferol

vitamin D2 methacrylate

vitamin D2 methacrylate

Conditions
ConditionsYield
With dmap In diethyl ether at 50℃;95%
chloro-trimethyl-silane
75-77-4

chloro-trimethyl-silane

Calciferol
50-14-6

Calciferol

vitamin D2 trimethylsilyl ether
2754-48-5

vitamin D2 trimethylsilyl ether

Conditions
ConditionsYield
With 1,1,1,3,3,3-hexamethyl-disilazane In tetrahydrofuran for 0.5h; Heating;94%
succinic acid anhydride
108-30-5

succinic acid anhydride

Calciferol
50-14-6

Calciferol

ergocalciferol hemisuccinate
1373140-59-0

ergocalciferol hemisuccinate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 24h; Inert atmosphere; Darkness;93%
With pyridine
Calciferol
50-14-6

Calciferol

A

10(R),19-dihydrovitamin D2
807-27-2

10(R),19-dihydrovitamin D2

B

10(S),19-dihydrovitamin D2
65377-86-8

10(S),19-dihydrovitamin D2

Conditions
ConditionsYield
With bis(cyclopentadienyl)titanium dichloride; lithium aluminium tetrahydride In tetrahydrofuran for 2.5h;A 10%
B 90%
With bis(cyclopentadienyl)titanium dichloride; sodium bis(2-methoxyethoxy)aluminium dihydride In tetrahydrofuran; toluene for 1.5h; Product distribution; Ambient temperature; var. reducing agents, ratios of reagents, solvents, and reaction time; other analogues of vitamin D2;A 60%
B 40%
With bis(cyclopentadienyl)titanium dichloride In tetrahydrofuran; toluene for 1.5h; Ambient temperature;A 60%
B 40%
Calciferol
50-14-6

Calciferol

1,1'-carbonyldiimidazole
530-62-1

1,1'-carbonyldiimidazole

Imidazole-1-carboxylic acid (S)-4-methylene-3-[2-[(1R,3aS,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexyl ester
286949-85-7

Imidazole-1-carboxylic acid (S)-4-methylene-3-[2-[(1R,3aS,7aR)-7a-methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-(4E)-ylidene]-eth-(Z)-ylidene]-cyclohexyl ester

Conditions
ConditionsYield
With triethylamine In dichloromethane for 2h; Condensation; Heating;90%
Calciferol
50-14-6

Calciferol

ercalcidiol
21343-40-8

ercalcidiol

Conditions
ConditionsYield
With dihydrogen peroxide In aq. phosphate buffer at 40℃; for 1h; pH=7; Enzymatic reaction; regioselective reaction;90%
With NADPH; NADPH-P450 reductase In various solvent(s) at 37℃; pH=7.7; Enzyme kinetics;
With coprinopsis cinerea peroxygenase; dihydrogen peroxide In aq. phosphate buffer; acetone at 40℃; for 1h; pH=7; Reagent/catalyst; Enzymatic reaction;
4-Phenyl-1,2,4-triazolidine-3,5-dione
4233-33-4

4-Phenyl-1,2,4-triazolidine-3,5-dione

Calciferol
50-14-6

Calciferol

6(S),19-(4-phenyl-3,5-dioxo-1,2,4-triazolidine-1,2-diyl)-3β-hydroxy-9,10-secoergosta-5(10),7(E),22(E)-triene
104973-27-5

6(S),19-(4-phenyl-3,5-dioxo-1,2,4-triazolidine-1,2-diyl)-3β-hydroxy-9,10-secoergosta-5(10),7(E),22(E)-triene

Conditions
ConditionsYield
In ethyl acetate at 0℃; for 1h;86%
2-oxo-2H-chromene-3-carboxylic acid
531-81-7

2-oxo-2H-chromene-3-carboxylic acid

Calciferol
50-14-6

Calciferol

C38H48O4

C38H48O4

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 0.25h; Inert atmosphere; Microwave irradiation;85%
6-bromocoumarin-3-carboxylic acid
2199-87-3

6-bromocoumarin-3-carboxylic acid

Calciferol
50-14-6

Calciferol

C38H47BrO4

C38H47BrO4

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 0.25h; Inert atmosphere; Microwave irradiation;84%
7-methyl-2-oxo-2H-chromene-3-carboxylic acid
1049115-94-7

7-methyl-2-oxo-2H-chromene-3-carboxylic acid

Calciferol
50-14-6

Calciferol

C39H50O4

C39H50O4

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 0.25h; Inert atmosphere; Microwave irradiation;83%
6-chloro-2-oxo-2H-chromene-3-carboxylic acid
883-92-1

6-chloro-2-oxo-2H-chromene-3-carboxylic acid

Calciferol
50-14-6

Calciferol

C38H47ClO4

C38H47ClO4

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 0.25h; Inert atmosphere; Microwave irradiation;81%
Calciferol
50-14-6

Calciferol

(1R,3aR,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-one
55812-80-1, 55870-05-8, 70144-73-9

(1R,3aR,7aR)-7a-Methyl-1-((E)-(1R,4R)-1,4,5-trimethyl-hex-2-enyl)-octahydro-inden-4-one

Conditions
ConditionsYield
Stage #1: Calciferol With potassium permanganate In ethanol; water at -15℃;
Stage #2: With pyridine; lead(IV) tetraacetate In dichloromethane at -15℃;
80%
Product distribution; Ambient temperature; degradation;
With potassium permanganate; sulfuric acid; benzene
Calciferol
50-14-6

Calciferol

C13H24O2

C13H24O2

Conditions
ConditionsYield
Stage #1: Calciferol With ozone
Stage #2: With sodium tetrahydroborate In methanol at -78℃;
80%
Calciferol
50-14-6

Calciferol

6,8-dichlorocoumarin-3-carboxylic acid
2199-86-2

6,8-dichlorocoumarin-3-carboxylic acid

C38H46Cl2O4

C38H46Cl2O4

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane for 0.25h; Inert atmosphere; Microwave irradiation;80%
1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine
37149-18-1

1-oxyl-4-carboxyl-2,2,6,6-tetramethylpiperidine

Calciferol
50-14-6

Calciferol

(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexanyl 2,2,6,6-tetra-methylpiperidine-1-oxyl-4-carboxylate

(1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(E,1R,4R)-1,4,5-trimethylhex-2-enyl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexanyl 2,2,6,6-tetra-methylpiperidine-1-oxyl-4-carboxylate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 26h; Inert atmosphere;76%
Calciferol
50-14-6

Calciferol

(1R,3aR,7aR)-1-((S)-1-hydroxypropan-2-yl)-7a-methyloctahydro-1H-inden-4-ol
185997-26-6

(1R,3aR,7aR)-1-((S)-1-hydroxypropan-2-yl)-7a-methyloctahydro-1H-inden-4-ol

Conditions
ConditionsYield
With sodium tetrahydroborate; ozone In methanol; dichloromethane at -78℃;75%
Stage #1: Calciferol With sodium hydrogencarbonate; ozone In methanol; dichloromethane at -78℃;
Stage #2: With sodium tetrahydroborate In methanol; dichloromethane at -78 - 0℃;
60%
Stage #1: Calciferol With sodium hydrogencarbonate; ozone In methanol; dichloromethane at 20℃;
Stage #2: With sodium tetrahydroborate
50%
With ozone
Multi-step reaction with 2 steps
1: ozonolysis
2: sodium tetrahydroborate
View Scheme
Calciferol
50-14-6

Calciferol

1-(1-hydroxypropan-2-yl)-7α-methyloctahydro-1H-inden-4-ol

1-(1-hydroxypropan-2-yl)-7α-methyloctahydro-1H-inden-4-ol

Conditions
ConditionsYield
Stage #1: Calciferol With sodium hydrogencarbonate In methanol; dichloromethane at -78℃; Inert atmosphere;
Stage #2: With ozone In methanol; dichloromethane for 48h;
Stage #3: With methanol; sodium tetrahydroborate In dichloromethane at 20℃;
75%
Calciferol
50-14-6

Calciferol

acetic anhydride
108-24-7

acetic anhydride

ergocalciferol acetate
2579-08-0

ergocalciferol acetate

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 0℃; for 0.0833333h;71%
With trimethylsilyl trifluoromethanesulfonate In dichloromethane at 0℃; for 0.0833333h;71%
Calciferol
50-14-6

Calciferol

(4R,7aR)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-4-((R,Z)-1-hydroxy-2-((S)-5-hydroxy-2-methylenecyclohexylidene)ethyl)-7a-methyloctahydro-1H-inden-4-ol
84985-78-4

(4R,7aR)-1-((2R,5R,E)-5,6-dimethylhept-3-en-2-yl)-4-((R,Z)-1-hydroxy-2-((S)-5-hydroxy-2-methylenecyclohexylidene)ethyl)-7a-methyloctahydro-1H-inden-4-ol

Conditions
ConditionsYield
With potassium permanganate70%
With potassium permanganate In ethanol at -20℃; for 2h;65%
With potassium permanganate In ethanol; water at -30 - 45℃;1.9 g
With potassium permanganate
With potassium permanganate In ethanol; water at -45 - 20℃; for 4.5h; regioselective reaction;
Calciferol
50-14-6

Calciferol

[1S-[1β(R*),3aα,7aβ]]-octahydro-1-(2-hydroxy-1-methylethyl)-7a-methyl-4H-inden-4-one
79918-70-0

[1S-[1β(R*),3aα,7aβ]]-octahydro-1-(2-hydroxy-1-methylethyl)-7a-methyl-4H-inden-4-one

Conditions
ConditionsYield
Stage #1: Calciferol With ozone In methanol; dichloromethane at -70℃;
Stage #2: With sodium tetrahydroborate In methanol; dichloromethane
68%
Multi-step reaction with 3 steps
1: acetonitrile
2: ruthenium trichloride; sodium periodate / acetonitrile; ethyl acetate; water
3: ruthenium trichloride; sodium periodate / acetonitrile; ethyl acetate; water
View Scheme
Calciferol
50-14-6

Calciferol

(3S,5Z,7Ξ)-9,10-seco-8ξ-ergosta-5,10(19),22t-triene-3,7,8-triol
84985-78-4, 54661-20-0

(3S,5Z,7Ξ)-9,10-seco-8ξ-ergosta-5,10(19),22t-triene-3,7,8-triol

Conditions
ConditionsYield
With potassium permanganate In ethanol; water at -20 - 40℃; for 0.75h;65%
With potassium permanganate In tetrahydrofuran; water65%
With potassium permanganate In ethanol at -30 - 45℃; for 4.16667h;62.7%
With potassium permanganate In ethanol; water40.4%
With potassium permanganate
Calciferol
50-14-6

Calciferol

chlorophosphoric acid diphenyl ester
2524-64-3

chlorophosphoric acid diphenyl ester

ergocalciferol diphenyl phosphate

ergocalciferol diphenyl phosphate

Conditions
ConditionsYield
With titanium(IV) tetrabutoxide; triethylamine In dichloromethane at 20℃; for 20h;63%
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