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Beijing Scrianen Pharmaceutical Co.,Ltd

Manufacturers, GMP products, long-term stable supply Application:Antitumor drugs Port:Tianjin/Qingdao/Shanghai

Cyclophosphamide

Cas:50-18-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Cyclophosphamide

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

factory supply 98% Cyclophosphamide powder

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $25.0 / 500.0

Type:Trading Company

inquiry

Kono Chem Co.,Ltd

Specifications: Name: Cyclophosphamide Specification: 99% CAS NO.:50-18-0 Appearance: white crystalline powder Molecular weight: 261.09 Molecular formula:C7H15Cl2N2O2P Density:1.33 g/cm3

CAS:50-18-0 Cyclophosphamide high quality

Cas:50-18-0

Min.Order:1 Kilogram

Negotiable

Type:Other

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Wuhan Fortuna Chemical Co.,Ltd is a professional integrative chemical enterprise with 18 years exporting experience,which is being engaged in Pharmaceutical and its intermediates, Food and Feed additives, Fine chemicals. Appearance:White crystalline

Broad-spectrum anti-tumor API Cyclophosphamide CAS NO 50-18-0 CTX

Cas:50-18-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

Cyclophosphamide for injection 500mg/vial;1g/vial;2g/vial

Cas:50-18-0

Min.Order:1 Gram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Cyclophosphamide

Cas:50-18-0

Min.Order:1

Negotiable

Type:Other

inquiry

Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Cyclophosphamide 50-18-0 GMP Manufacturer

Cas:50-18-0

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Shanghai Seasonsgreen Chemical Co.,Ltd

Shanghai Seasonsgreen Chemical is a high-tech research and development, production, sale and custom synthesis set in one high-tech chemical products enterprises. Our sales and marketing division is located in Shanghai, serving international pharmaceu

lower price High quality Cyclophosphamide

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

Cyclophosphamide -- CHemwill

Cas:50-18-0

Min.Order:1 Metric Ton

FOB Price: $1.0

Type:Manufacturers

inquiry

Hubei DiBo chemical co., LTD

Name:cyclophosphamide CAS:50-18-0 Grade:For chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability

CAS:50-18-0 Cyclophosphamide high quality

Cas:50-18-0

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

high quality Cyclophosphamide

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

50-18-0 Cyclophosphamide

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $15.0 / 50.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 50-18-0 with best quality

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Henan Sinotech Import&Export Corporation

Alias: 2-(bis(2-chloroethyl)amino)-1,3,2-oxazaphosphorinane 2-oxide; 1-(bis(2-chloroethyl)amino)-1-oxo-2-aza-5-oxaphosphoridine; 2-(di(2-chloroethyl)amino)-1-oxa-3-aza-2-phosphacyclohexane 2-oxide; N,N-bis(2-chloroethyl)-1,3,2-oxazaphosphinan-2-ami

2-(Bis(2-chloroethyl)amino)-2H-1,3,2-oxazaphosphorine 2-oxide

Cas:50-18-0

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White or almost white crystalline powder Storage:R.T Package:25kg/drum Application:API Transportation:Express/Sea/Air Port:Any port in China

High Quality Cyclophosphamide cas 50-18-0 in stock

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $150.0 / 200.0

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:powder Storage:Store in sealed containers at cool & dry pla

China high quality API raw material CAS:50-18-0 Cyclophosphamide powder

Cas:50-18-0

Min.Order:100 Gram

Negotiable

Type:Other

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide 50-18-0

Cas:50-18-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Qingdao Beluga Import and Export Co., LTD

Cyclophosphamide CAS:50-18-0 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediat

Cyclophosphamide CAS:50-18-0

Cas:50-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide

Cas:50-18-0

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:50-18-0

Cas:50-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei CuiRan Biotechnology Co., Ltd

Hubei CuiRan Biotechnology Co., Ltd is a leading company in the research, development, manufacture and marketing of High Quality Phytochemicals and Extracts(especially Active Ingredients from Traditional Chinese Medicine,Traditional Chinese Medicine)

Cyclophosphamide

Cas:50-18-0

Min.Order:10 Milligram

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

Cyclophosphamide

Cas:50-18-0

Min.Order:1 Kilogram

FOB Price: $10.0 / 100.0

Type:Lab/Research institutions

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Cyclophosphamide

Cas:50-18-0

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Cyclophosphamide

Cas:50-18-0

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality Cyclophosphamide

Cas:50-18-0

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

Hangzhou Lingrui Chemical Co.,Ltd.

Lowest price CyclophosphamideAppearance:white powder Storage:keep cool Package:according to customers' requirements Application:pharmaceutical intermediate and other research Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or C

Lowest price Cyclophosphamide

Cas:50-18-0

Min.Order:1 Gram

Negotiable

Type:Other

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white powder Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediates Tr

2H-1,3,2-Oxazaphosphorin-2-amine,N,N-bis(2-chloroethyl)tetrahydro-, 2-oxide

Cas:50-18-0

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Lyander (Xiamen) Medical Technology Co., LTD

Lyander’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. Lyander can provide different quantities of cu

Cyclophosphamide

Cas:50-18-0

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

1,2-dichloro-ethane
107-06-2

1,2-dichloro-ethane

2-chloro-2-oxo-1,3,2λ3-oxazaphosphinane
5638-58-4

2-chloro-2-oxo-1,3,2λ3-oxazaphosphinane

cyclophosphamide
50-18-0

cyclophosphamide

Conditions
ConditionsYield
With ammonia at 120℃; under 3040.2 Torr; for 2h; Molecular sieve;92.3%
With ammonia; triethylamine at 20℃; under 375.038 Torr; for 2.3h;90.6%
bis-(2-chloroethyl)amine hydrochloride
821-48-7

bis-(2-chloroethyl)amine hydrochloride

propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

cyclophosphamide
50-18-0

cyclophosphamide

Conditions
ConditionsYield
Stage #1: bis-(2-chloroethyl)amine hydrochloride With 4-methyl-morpholine; trichlorophosphate In neat (no solvent) at 4 - 20℃; for 5h; Green chemistry;
Stage #2: propan-1-ol-3-amine In neat (no solvent) at 4 - 20℃; for 18h; Reagent/catalyst; Green chemistry;
77.6%
3-(benzyloxy)cyclophosphamide
78336-01-3

3-(benzyloxy)cyclophosphamide

A

cyclophosphamide
50-18-0

cyclophosphamide

B

3-hydroxycyclophosphamide
78336-02-4

3-hydroxycyclophosphamide

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate under 2068.6 - 2327.2 Torr; for 72h; Ambient temperature; Yield given;A n/a
B 22%
With hydrogen; palladium on activated charcoal In ethyl acetate under 2068.6 - 2327.2 Torr; for 72h; Ambient temperature; Yields of byproduct given;A n/a
B 22%
2-bis-[2-(1,3,5-trimethyl-1,3,5,2-triazaphosphorin-4,6-dion-2-yloxy)ethylamino]-tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxide

2-bis-[2-(1,3,5-trimethyl-1,3,5,2-triazaphosphorin-4,6-dion-2-yloxy)ethylamino]-tetrahydro-2H-1,3,2-oxazaphosphorin-2-oxide

A

cyclophosphamide
50-18-0

cyclophosphamide

B

2-chloro-1,3,5-trimethyl-2-oxo-2λ5-[1,3,5,2]triazaphosphinane-4,6-dione
10199-13-0

2-chloro-1,3,5-trimethyl-2-oxo-2λ5-[1,3,5,2]triazaphosphinane-4,6-dione

Conditions
ConditionsYield
With sulfuryl dichloride In dichloromethane at 0℃; for 1h;A 10.9%
B n/a
N,N-di(2-chloroethyl)amidophosphoric acid dichloride
127-88-8

N,N-di(2-chloroethyl)amidophosphoric acid dichloride

propan-1-ol-3-amine
156-87-6

propan-1-ol-3-amine

cyclophosphamide
50-18-0

cyclophosphamide

Conditions
ConditionsYield
With 1,4-dioxane; triethylamine
With triethylamine In ethyl acetate
With triethylamine In tetrachloromethane at 0℃; for 10h;
With triethanolamine In dichloromethane
(2-Oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-bis-(2-trimethylsilanyloxy-ethyl)-amine
195966-75-7

(2-Oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-bis-(2-trimethylsilanyloxy-ethyl)-amine

cyclophosphamide
50-18-0

cyclophosphamide

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 76.3 percent / CH2Cl2 / 24 h / Ambient temperature
2: 10.9 percent / SO2Cl2 / CH2Cl2 / 1 h / 0 °C
View Scheme
oxyphosphorous chloride

oxyphosphorous chloride

(3,3-Diacetatepropyl)-N,N-bis(2-chloroethyl) phosphorodiamide

(3,3-Diacetatepropyl)-N,N-bis(2-chloroethyl) phosphorodiamide

bis-(2-chloroethyl)amine hydrochloride
821-48-7

bis-(2-chloroethyl)amine hydrochloride

A

cyclophosphamide
50-18-0

cyclophosphamide

B

(3,3-Diacetatepropyl)-O-methyl-N-bis(2-chloroethyl)phosphor amide

(3,3-Diacetatepropyl)-O-methyl-N-bis(2-chloroethyl)phosphor amide

Conditions
ConditionsYield
With triethylamine In methanol; dichloromethane
2(R)--3-<(R)-α-methylbenzyl>-1,3,2-oxazaphosphorinane 2-oxide
58028-71-0

2(R)--3-<(R)-α-methylbenzyl>-1,3,2-oxazaphosphorinane 2-oxide

A

cyclophosphamide
50-18-0

cyclophosphamide

B

S(-)-cyclophosphamide

S(-)-cyclophosphamide

Conditions
ConditionsYield
With ammonium sulfate In (2S)-N-methyl-1-phenylpropan-2-amine hydrate; trifluoroacetic acid
cyclophosphamide
50-18-0

cyclophosphamide

3-bromocyclophosphamide

3-bromocyclophosphamide

Conditions
ConditionsYield
With bromine; potassium carbonate In dichloromethane for 2h;100%
cyclophosphamide
50-18-0

cyclophosphamide

3-chlorocyclophosphamide

3-chlorocyclophosphamide

Conditions
ConditionsYield
With sodium hypochlorite In chloroform for 18h;87%
cyclophosphamide
50-18-0

cyclophosphamide

1-(2-chloro-ethyl)-tetrahydro-[1,3,2]diazaphospholo[2,1-b][1,3,2]oxazaphosphinine (S)-9-oxide
64724-10-3

1-(2-chloro-ethyl)-tetrahydro-[1,3,2]diazaphospholo[2,1-b][1,3,2]oxazaphosphinine (S)-9-oxide

Conditions
ConditionsYield
With sodium hydride In diethyl ether for 2.5h; Ambient temperature;64%
With sodium hydride In diethyl ether
With sodium hydride In tetrahydrofuran
cyclophosphamide
50-18-0

cyclophosphamide

chloral
75-87-6

chloral

(+/-)-2,2,2-trichloro-1-(3-N-cyclophosphamide)ethanol
75526-91-9

(+/-)-2,2,2-trichloro-1-(3-N-cyclophosphamide)ethanol

Conditions
ConditionsYield
With N,N-dimethyl-formamide at 30℃; Product distribution; Rate constant; var. time, var. ratio of reactants;62%
Ambient temperature;50%
rhodium(II) acetate

rhodium(II) acetate

cyclophosphamide
50-18-0

cyclophosphamide

2Rh(2+)*4CH3COO(1-)*2((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))=Rh2(OOCCH3)4((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))2

2Rh(2+)*4CH3COO(1-)*2((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))=Rh2(OOCCH3)4((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))2

Conditions
ConditionsYield
In ethanol Rh(II) acetate was dissolved in a min. amt. of ethanol and mixed with cyclophosphamide in 1:3 molar ratio dissolved in a min. amt. of ethanol., refluxed for 1 h; solvent removed in a nitrogen blanket, residue was washed several times wih ether, filtered, dried under vac. at room temp., elem. anal.;60%
cyclophosphamide
50-18-0

cyclophosphamide

rhodium(II)(CH3CH2CO2)2

rhodium(II)(CH3CH2CO2)2

2Rh(2+)*4CH3CH2COO(1-)*2((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))=Rh2(OOCCH2CH3)4((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))2

2Rh(2+)*4CH3CH2COO(1-)*2((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))=Rh2(OOCCH2CH3)4((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))2

Conditions
ConditionsYield
In ethanol Rh(II) propionate was dissolved in a min. amt. of ethanol and mixed with cyclophosphamide in 1:3 molar ratio dissolved in a min. amt. of ethanol., refluxed for 1 h; solvent removed in a nitrogen blanket, residue was washed several times wih ether, filtered, dried under vac. at room temp., elem. anal.;57%
cyclophosphamide
50-18-0

cyclophosphamide

Rh-butyrate

Rh-butyrate

Rh2(butyrate)4((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))2

Rh2(butyrate)4((ClCH2CH2)2NP(O)(OCH2CH2CH2NH))2

Conditions
ConditionsYield
In ethanol Rh(II) butyrate was dissolved in a min. amt. of ethanol and mixed with cyclophosphamide in 1:3 molar ratio dissolved in a min. amt. of ethanol., refluxed for 1 h; solvent removed in a nitrogen blanket, residue was washed several times wih ether, filtered, dried under vac. at room temp., elem. anal.;55%
cyclophosphamide
50-18-0

cyclophosphamide

chloral
75-87-6

chloral

2,2,2-trichloro-1-(3-N-(-)-cyclophosphamide)ethanol
75526-91-9

2,2,2-trichloro-1-(3-N-(-)-cyclophosphamide)ethanol

Conditions
ConditionsYield
With N,N-dimethyl-formamide Ambient temperature;46%
cyclophosphamide
50-18-0

cyclophosphamide

Benzylidenemalononitrile
2700-22-3

Benzylidenemalononitrile

((2-(bis(2-chloroethyl)amino)-2-oxo-1,3,2λ5-oxazaphosphinan-4-yl)(phenyl)methyl)propanedinitrile

((2-(bis(2-chloroethyl)amino)-2-oxo-1,3,2λ5-oxazaphosphinan-4-yl)(phenyl)methyl)propanedinitrile

Conditions
ConditionsYield
With eosin y In dichloromethane at 20℃; for 16h; Inert atmosphere; Irradiation; chemoselective reaction;44%
methanol
67-56-1

methanol

cyclophosphamide
50-18-0

cyclophosphamide

(+/-)-4-β-methoxycyclophosphamide

(+/-)-4-β-methoxycyclophosphamide

Conditions
ConditionsYield
With tetraethylammonium tosylate Electrochemical reaction; 2.2 F/mol electricity, i=15 mA;40%
cyclophosphamide
50-18-0

cyclophosphamide

4-hydroxycyclophosphamide
40277-05-2

4-hydroxycyclophosphamide

Conditions
ConditionsYield
With dihydrogen peroxide; unspecific peroxygenase of Marasmius rotula In aq. acetate buffer at 25℃; for 1h; Reagent/catalyst; Enzymatic reaction;32%
With dihydrogen peroxide; iron(II) sulfate
Multi-step reaction with 2 steps
1: (i) O3, (ii) H2O2
2: P(OEt)3
View Scheme
cyclophosphamide
50-18-0

cyclophosphamide

3-fluorocyclophosphamide

3-fluorocyclophosphamide

Conditions
ConditionsYield
With hypofluorous acid trifluoromethyl ester In dichloromethane at -78℃; for 3h;20%
cyclophosphamide
50-18-0

cyclophosphamide

2-[(2-chloro-2'-fluorodiethyl)amino]-2H-1,3,2-oxazaphosphorinane-2-oxide
5001-29-6

2-[(2-chloro-2'-fluorodiethyl)amino]-2H-1,3,2-oxazaphosphorinane-2-oxide

Conditions
ConditionsYield
With potassium fluoride; [2.2.2]cryptande In acetonitrile for 3h; Heating;10.7%
tert.-butylhydroperoxide
75-91-2

tert.-butylhydroperoxide

cyclophosphamide
50-18-0

cyclophosphamide

A

4-ketocyclophosphamide mustard
27046-19-1, 69580-11-6, 69580-12-7

4-ketocyclophosphamide mustard

B

4-(tert-butylperoxy)cyclophosphamide

4-(tert-butylperoxy)cyclophosphamide

Conditions
ConditionsYield
With ozone In water; acetone for 3h;A n/a
B 10%
cyclophosphamide
50-18-0

cyclophosphamide

N-(2-Hydroxy-ethyl)-N'-(3-hydroxy-propyl)-ethylendiamin
4512-07-6

N-(2-Hydroxy-ethyl)-N'-(3-hydroxy-propyl)-ethylendiamin

Conditions
ConditionsYield
With water
cyclophosphamide
50-18-0

cyclophosphamide

Phosphoric acid mono-{3-[2-(2-chloro-ethylamino)-ethylamino]-propyl} ester
45164-26-9

Phosphoric acid mono-{3-[2-(2-chloro-ethylamino)-ethylamino]-propyl} ester

Conditions
ConditionsYield
With methanol; water
Multi-step reaction with 2 steps
1: NaH / tetrahydrofuran
View Scheme
cyclophosphamide
50-18-0

cyclophosphamide

Phosphoric acid mono-{3-[2-(2-hydroxy-ethylamino)-ethylamino]-propyl} ester
45164-27-0

Phosphoric acid mono-{3-[2-(2-hydroxy-ethylamino)-ethylamino]-propyl} ester

Conditions
ConditionsYield
In water
With water
cyclophosphamide
50-18-0

cyclophosphamide

2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-ol; 2-(2-chloro-ethylamino)-ethanol salt
118872-44-9

2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-ol; 2-(2-chloro-ethylamino)-ethanol salt

Conditions
ConditionsYield
With water
cyclophosphamide
50-18-0

cyclophosphamide

4-hydroperoxycyclophosphamide
39800-16-3, 146566-40-7

4-hydroperoxycyclophosphamide

Conditions
ConditionsYield
(i) O3, (ii) H2O2; Multistep reaction;
With ozone
cyclophosphamide
50-18-0

cyclophosphamide

chloroacetyl chloride
79-04-9

chloroacetyl chloride

2-[bis-(2-chloro-ethyl)-amino]-3-chloroacetyl-[1,3,2]oxazaphosphinane (R)-2-oxide
72578-77-9

2-[bis-(2-chloro-ethyl)-amino]-3-chloroacetyl-[1,3,2]oxazaphosphinane (R)-2-oxide

Conditions
ConditionsYield
In tetrahydrofuran
cyclophosphamide
50-18-0

cyclophosphamide

GLUTATHIONE
70-18-8

GLUTATHIONE

(S)-2-Amino-4-((R)-1-(carboxymethyl-carbamoyl)-2-{2-[(2-chloro-ethyl)-(2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-amino]-ethylsulfanyl}-ethylcarbamoyl)-butyric acid
146697-02-1

(S)-2-Amino-4-((R)-1-(carboxymethyl-carbamoyl)-2-{2-[(2-chloro-ethyl)-(2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-amino]-ethylsulfanyl}-ethylcarbamoyl)-butyric acid

Conditions
ConditionsYield
With ammonium hydroxide In water for 24h; Ambient temperature; or with rabbit liver microsomal glutathione S-transferase, 37 deg C;
cyclophosphamide
50-18-0

cyclophosphamide

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

N-(tert-butyldimethylsilyl)cyclophosphamide

N-(tert-butyldimethylsilyl)cyclophosphamide

Conditions
ConditionsYield
With triethylamine In diethyl ether at 25℃; for 24h;
cyclophosphamide
50-18-0

cyclophosphamide

ethanol
64-17-5

ethanol

Conditions
ConditionsYield
With potassium hydroxide; aluminum nickel In methanol Product distribution; degradation under various conditions with preparation of nonmutagenic reaction mixtures of products;
cyclophosphamide
50-18-0

cyclophosphamide

A

Carboxyphosphamide
22788-18-7

Carboxyphosphamide

B

aldophosphamide
35144-64-0

aldophosphamide

C

4-hydroxycyclophosphamide
40277-05-2

4-hydroxycyclophosphamide

D

4-ketocyclophosphamide mustard
27046-19-1, 69580-11-6, 69580-12-7

4-ketocyclophosphamide mustard

Conditions
ConditionsYield
pharmacokinetics, metabolism;
cyclophosphamide
50-18-0

cyclophosphamide

4-ketocyclophosphamide mustard
27046-19-1, 69580-11-6, 69580-12-7

4-ketocyclophosphamide mustard

Conditions
ConditionsYield
With ethylenediaminetetraacetic acid; dihydrogen peroxide; iron(II) sulfate In water for 120h; Ambient temperature;60 % Spectr.
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