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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

High purity Benzyl chloroformate 98% TOP1 supplier in China

Cas:501-53-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Benzyl Chloroformate supplier in China

Cas:501-53-1

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Assay (Ursolic acid) 98%min 98.22% ----------------------------------------------------------------

High purity 501-53-1 Benzyl Chloroformate

Cas:501-53-1

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Trading Company

inquiry

Hefei TNJ chemical industry co.,ltd

ISO Certificaiton Technology: Technology innovation is our eternal pursuit,or we will be left behind.Our technology experts,all from famous universities and institutes,has rich experience and high achievements in chemical research.This makes sure

Benzyl Chloroformate

Cas:501-53-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Henan Allgreen Chemical Co.,Ltd

he company has advanced technology, as well as a large number of excellent R & D team, to provide customers from the grams to one hundred kilograms and tons of high-quality products, competitive prices and quality se T rvice Appearance:White or

Benzyl ChloroforMate (30-35% in Toluene)

Cas:501-53-1

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Benzyl chloroformate

Cas:501-53-1

Min.Order:1

Negotiable

Type:Other

inquiry

Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

Benzyl chloroformate

Cas:501-53-1

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

inquiry

Henan Tianfu Chemical Co., Ltd.

Benzyl chloroformate 501-53-1 Benzyl chloroformate Basic information Product Name: Benzyl chloroformate Synonyms: Benzyl carbonochloridate;Benzyl chloridocarbonate;Benzyl chlorocarbona

Benzyl chloroformate 501-53-1

Cas:501-53-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Sinotech Import&Export Corporation

Product Name:Benzyl chloroformate Synonyms:Benzyl carbonochloridate;Benzyl chloridocarbonate;Benzyl chlorocarbonate;benzylcarbonochloridate;Benzylcarbonyl chloride;benzylcarbonylchloride;benzylchlorocarbonate;Bzcf CAS:501-53-1 MF:C8H7ClO2

Benzyl chloroformate CAS:501-53-1

Cas:501-53-1

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

inquiry

Shijiazhuang Sdyano Fine Chemical Co., Ltd

1. Best prices with satisfied quality; 2. It's clients' right to choose the package's Courier (EMS, DHL, FedEx, UPS); 3.It's clients' right to choose the packing way for his produccts from many recent effective packing ways;

Benzyl chloroformate

Cas:501-53-1

Min.Order:0 Metric Ton

Negotiable

Type:Trading Company

inquiry

Changchun Artel lmport and Export trade company

Price, service, company and transport advantage: 1.place of origin china with super quality by reasonable price. 2. it's customers' right to choose the package (ems, dhl, fedex, ups); 3. it's custo

BEST PRICE/Benzyl Chloroformate

Cas:501-53-1

Min.Order:10 Gram

Negotiable

Type:Trading Company

inquiry

Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Benzyl chloroformate

Cas:501-53-1

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

Benzyl ChloroforMate

Cas:501-53-1

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:Clear colorless liquid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package:25kg/drum, or as per your request. Application:For medicine , pesticide

Benzyl chloroformate

Cas:501-53-1

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

Benzyl chloroformate Manufacturer

Cas:501-53-1

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

1)quick response within 12 hours; 2)quality guarantee: all products are strictly tested by our qc, confirmed by qa and approved by third party lab in china, usa, canada, germany, uk, italy, france etc. 3) oem/odm available; 4) rea

Z-CLCAS NO.: 501-53-1

Cas:501-53-1

Min.Order:1 Gram

FOB Price: $4.0

Type:Lab/Research institutions

inquiry

Hangzhou Huarong Pharm Co., Ltd.

Hangzhou Huarong Pharm Co., Ltd.established since 2006 , has been actively developing specialty products for Finished Dosages, APIs, Intermediates, and Fine chemicals markets in North America, Europe, Korea, Japan, Mid-East and all over the World. Hu

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Hangzhou Zhongqi chem Co.,Ltd.

Located in Hangzhou National Hi-Tech Industrial Development Zone, zhongqichem is a technical company mainly focus on the Custom synthesis, manufacturing, sales of chemicals to various industries. Benefiting from the outstanding customer service and h

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hunan chemfish Pharmaceutical co.,Ltd

Appearance:95%+ Package:R&D,Pilot run Transportation:per client require Port:Express ,Air, Sea

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Kono Chem Co.,Ltd

high purity lowest priceAppearance:solid or liquid Storage:in sealed air resistant place Package:drum and bag Application:for pharma use Transportation:by sea or air Port:Beijing or Guangzhou

Benzyl Chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Other

inquiry

GIHI CHEMICALS CO.,LIMITED

high purity,in stock Package:25kg/drum,or as per customers'demand Application:API,or Intermediates,fine chemicals Transportation:air,sea,courier

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

JINHUA HUAYI CHEMICAL CO., LTD.

Jinhua huayi chemical co., ltd. is dedicated to the development, production and marketing of chemicals. On the basis of equality and mutual benefit, and under the principle of customer first, credit first, quality first, we are ready to join hands

Benzyl Chloroformate

Cas:501-53-1

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Fortuna Chemical Co.,Ltd

Best service,high quality and cheap price. Storage:Keep away from heat,sparks and flames. Package:25kg/50kg/200kg drum or Customer demand Application:Used as pharmaceutical intermediates Transportation:BY sea/air or by courier

Benzyl Chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Aecochem Corp.

Our clients, like BASF,CHEMO,Brenntag,ASR,Evonik,Merck and etc.Appearance:COA Storage:in stock Application:MSDS/TDS

Benzyl Chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Manufacturers

inquiry

Cartoon Ingredients Co., Ltd

Cartoon Ingredients Co.,Ltd.is located in NanJing, the capital of Jiangsu Province.with Convenient traffic As a manufacturer, the company mainly engaged in providing Food ingredients, Herbal extracts, Vitamins, APIs and Fine chemicals &a

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

Product Description Description & Specification Category Pharmaceutical Raw Materials, Fine Chemicals, Bulk drug Standard Medical standard

factory supply CAS 501-53-1 with competitive price

Cas:501-53-1

Min.Order:1 Kilogram

FOB Price: $112.0

Type:Trading Company

inquiry

Antimex Chemical Limied

Ansciep Chemical is a professional enterprise manufacturing and distributing fine chemicals and speciality chemicals. We have been dedicated to heterocycle compounds and phenyl rings for tens of years. This is our mature product for export. Our quali

Benzyl chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen AmoyChem Co.,Ltd

Amoychem is committed to providing the top-quality chemical products and services Internationally. We offer our customers with friendly, professional service and reliable, high performance products that have been manufactured according to the accredi

Benzylchlorformiat

Cas:501-53-1

Min.Order:0

Negotiable

Type:Other

inquiry

Hubei Langyou International Trading Co., Ltd

Top sale 501-53-1 Benzyl Chloroformate Application:Top sale 501-53-1 Benzyl Chloroformate

Top sale 501-53-1 Benzyl Chloroformate

Cas:501-53-1

Min.Order:0

Negotiable

Type:Other

inquiry

Synthetic route

O-benzyl S-methyl carbonothioate
22426-83-1

O-benzyl S-methyl carbonothioate

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With sulfuryl dichloride at 0 - 20℃; for 1h;100%
With sulfuryl dichloride at 20℃; for 1h;72%
With sulfuryl dichloride at 0 - 20℃; for 1h;72%
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

benzyl alcohol
100-51-6

benzyl alcohol

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With pyridine In dichloromethane at -5 - 10℃; for 13h; Reagent/catalyst; Temperature; Solvent;99%
With pyridine In dichloromethane98%
With pyridine In dichloromethane98%
S-ethyl O-benzyl carbonothioate
110177-67-8

S-ethyl O-benzyl carbonothioate

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With sulfuryl dichloride at 20℃; for 1h;81%
With sulfuryl dichloride at 0 - 20℃; for 1h;81%
1-adamantylfluoroformate
62087-82-5

1-adamantylfluoroformate

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran at 0 - 20℃;76%
phosgene
75-44-5

phosgene

benzyl alcohol
100-51-6

benzyl alcohol

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With toluene anfangs unter Kuehlung;
at -8℃;
With 2,3-Dimethylaniline
benzyl carbonochloridate
39608-52-1

benzyl carbonochloridate

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With thionyl chloride at 90℃; for 3h;
With thionyl chloride for 6h; Chlorination; Heating;
With thionyl chloride for 4h; Reflux;
With thionyl chloride at 90℃; for 2h;
benzyl alcohol
100-51-6

benzyl alcohol

trichloromethyl chloroformate
503-38-8

trichloromethyl chloroformate

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With pyrographite In tetrahydrofuran at 20℃; for 1h; Condensation;
With dmap In toluene at 20℃; for 24h;
benzyl alcohol
100-51-6

benzyl alcohol

polymer-supported N-benzyloxy-2-nitrobenzenesulfonamide

polymer-supported N-benzyloxy-2-nitrobenzenesulfonamide

A

benzyl chloroformate
501-53-1

benzyl chloroformate

B

D-lysine

D-lysine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1.1: sulfur; DBU / dimethylsulfoxide / 5 h / 20 °C / 760 Torr
1.2: 67 percent / dimethylsulfoxide / 1 h / 20 °C
2.1: 100 percent / SO2Cl2 / 1 h / 0 - 20 °C
View Scheme
Thiocarbonic acid O-benzyl ester
125178-42-9

Thiocarbonic acid O-benzyl ester

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: tetrahydrofuran / 2 h / 20 °C / 750.06 Torr
2: 81 percent / sulfuryl chloride / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 2 steps
1: 1.62 g / tetrahydrofuran / 16 h / 20 °C / 750.06 Torr
2: 72 percent / sulfuryl chloride / 1 h / 0 - 20 °C
View Scheme
benzyl alcohol
100-51-6

benzyl alcohol

BocNH-C(=NBoc)-SCH2-terminated resin

BocNH-C(=NBoc)-SCH2-terminated resin

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: DBU / tetrahydrofuran / 1 h / 20 °C / 750.06 Torr
2: tetrahydrofuran / 2 h / 20 °C / 750.06 Torr
3: 81 percent / sulfuryl chloride / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1: DBU / tetrahydrofuran / 1 h / 20 °C / 750.06 Torr
2: 1.62 g / tetrahydrofuran / 16 h / 20 °C / 750.06 Torr
3: 72 percent / sulfuryl chloride / 1 h / 0 - 20 °C
View Scheme
Multi-step reaction with 3 steps
1: sulfur; DBU / tetrahydrofuran / 6 h / 80 °C / 7500.6 Torr
2: tetrahydrofuran / 2 h / 20 °C / 750.06 Torr
3: 81 percent / sulfuryl chloride / 1 h / 0 - 20 °C
View Scheme
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

phenylmethanethiol
100-53-8

phenylmethanethiol

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With triethylamine In dichloromethane
bis(trichloromethyl) carbonate
32315-10-9

bis(trichloromethyl) carbonate

phenylmethanethiol
100-53-8

phenylmethanethiol

2-amino-3-methylbutane
598-74-3

2-amino-3-methylbutane

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With triethylamine In dichloromethane
9,10-dihydro-3-methyl-4H-thieno[3,4-b][1,5]benzodiazepin-10-one
74137-84-1

9,10-dihydro-3-methyl-4H-thieno[3,4-b][1,5]benzodiazepin-10-one

A

4-(benzyloxycarbonyl)-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one

4-(benzyloxycarbonyl)-4,9-dihydro-3-methyl-10H-thieno[3,4-b][1,5]benzodiazepin-10-one

B

benzyl chloroformate
501-53-1

benzyl chloroformate

benzyl 2-oxo-2-(pyren-1-yl)ethyl carbonate
1449331-28-5

benzyl 2-oxo-2-(pyren-1-yl)ethyl carbonate

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: water / acetonitrile / pH 7.5 / Photolysis; Inert atmosphere
2: sodium carbonate / toluene / 6 h / 0 °C
View Scheme
chloroform
67-66-3

chloroform

benzyl alcohol
100-51-6

benzyl alcohol

benzyl chloroformate
501-53-1

benzyl chloroformate

Conditions
ConditionsYield
With oxygen at 20℃; for 3h; Irradiation;
tryptamine
61-54-1

tryptamine

benzyl chloroformate
501-53-1

benzyl chloroformate

(2-indol-3-yl-ethyl)-carbamic acid benzyl ester
38750-13-9

(2-indol-3-yl-ethyl)-carbamic acid benzyl ester

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In chloroform at 20℃; for 1h;100%
With N-ethyl-N,N-diisopropylamine In chloroform at 0 - 20℃; for 1h;100%
With sodium hydroxide In tetrahydrofuran97%
ethanolamine
141-43-5

ethanolamine

benzyl chloroformate
501-53-1

benzyl chloroformate

benzyl 2-hydroxyethylcarbamate
77987-49-6

benzyl 2-hydroxyethylcarbamate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0 - 20℃; for 1h;100%
In benzene for 0.5h; Ambient temperature;95%
With triethylamine In dichloromethane at 20℃; for 6h; Large scale;95.3%
2-bromoethylamine
107-09-5

2-bromoethylamine

benzyl chloroformate
501-53-1

benzyl chloroformate

benzyl N-(2-bromoethyl)carbamate
53844-02-3

benzyl N-(2-bromoethyl)carbamate

Conditions
ConditionsYield
With triethylamine In dichloromethane at 0℃; for 6h;100%
With sodium hydroxide
In sodium hydroxide; acetone
With triethylamine In N,N-dimethyl-formamide at 0℃;
L-alanin
56-41-7

L-alanin

benzyl chloroformate
501-53-1

benzyl chloroformate

N-Cbz-Ala
1142-20-7

N-Cbz-Ala

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 20℃;100%
With sodium hydroxide In water at 0 - 20℃; for 5h;99%
With sodium carbonate In water at 0 - 20℃; for 24h;98%
3-aminobutyric acid
2835-82-7

3-aminobutyric acid

benzyl chloroformate
501-53-1

benzyl chloroformate

3-benzyloxycarbonylaminobutyric acid
51440-81-4

3-benzyloxycarbonylaminobutyric acid

Conditions
ConditionsYield
With sodium hydroxide In water at 20℃;100%
With sodium hydroxide In tetrahydrofuran for 16h; Ambient temperature;97%
With sodium hydroxide In water; acetone for 1h; Ambient temperature;91%
L-valine
72-18-4

L-valine

benzyl chloroformate
501-53-1

benzyl chloroformate

(S)-N-(benzyloxycarbonyl)valine
1149-26-4

(S)-N-(benzyloxycarbonyl)valine

Conditions
ConditionsYield
With sodium hydrogencarbonate In water Inert atmosphere;100%
With sodium hydroxide In water at 0 - 20℃;100%
With potassium carbonate In water at 0 - 2℃; pH=1.5 - Ca. 2; Reagent/catalyst; pH-value; Temperature; Solvent;99%
L-serin
56-45-1

L-serin

benzyl chloroformate
501-53-1

benzyl chloroformate

N-(benzyloxycarbonyl)-L-serine
1145-80-8

N-(benzyloxycarbonyl)-L-serine

Conditions
ConditionsYield
With sodium hydrogencarbonate In diethyl ether; water at 0 - 20℃; for 6h;100%
With sodium hydroxide In water at 0℃; for 24h;94%
With sodium hydrogencarbonate for 4h; Ambient temperature;93%
L-leucine
61-90-5

L-leucine

benzyl chloroformate
501-53-1

benzyl chloroformate

Z-Leu-OH
2018-66-8

Z-Leu-OH

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 20℃;100%
With sodium hydroxide at 0℃; for 1h;99%
With sodium hydroxide In water at 20℃; for 2h;92%
benzyl chloroformate
501-53-1

benzyl chloroformate

DL-methionine
59-51-8

DL-methionine

N-(benzyloxycarbonyl)methionine
4434-61-1

N-(benzyloxycarbonyl)methionine

Conditions
ConditionsYield
With sodium hydrogencarbonate In diethyl ether for 5h;100%
In ethyl acetate Heating;31%
With sodium hydroxide at 0℃;
Schotten-Baumann reaction;
benzyl chloroformate
501-53-1

benzyl chloroformate

N-Benzyloxycarbonyl-taurine sodium salt
136027-16-2

N-Benzyloxycarbonyl-taurine sodium salt

Conditions
ConditionsYield
With sodium hydroxide a) 0 deg C, 30 min, b) 20 deg C, 2 h;100%
With sodium hydroxide In water for 0.5h;100%
With sodium hydroxide In 1,4-dioxane; water at 20℃; for 1h;82%
L-phenylalanine
63-91-2

L-phenylalanine

benzyl chloroformate
501-53-1

benzyl chloroformate

N-Cbz-L-Phe
1161-13-3

N-Cbz-L-Phe

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 20℃;100%
Stage #1: L-phenylalanine; benzyl chloroformate With sodium hydroxide In water at 0 - 20℃; for 1.5h;
Stage #2: With hydrogenchloride In water pH=4;
99%
With sodium hydroxide99%
L-Tyr-OMe
1080-06-4

L-Tyr-OMe

benzyl chloroformate
501-53-1

benzyl chloroformate

N-(benzyloxycarbonyl)-L-tyrosine methyl ester
13512-31-7

N-(benzyloxycarbonyl)-L-tyrosine methyl ester

Conditions
ConditionsYield
With sodium carbonate In water; acetone at 20℃; for 2h;100%
With sodium carbonate In dichloromethane; water at 0 - 20℃; for 2.5h;98%
With sodium hydrogencarbonate In chloroform at 25℃; for 3h;94%
benzyl chloroformate
501-53-1

benzyl chloroformate

aniline
62-53-3

aniline

N-(benzyloxycarbonyl)aniline
3422-02-4

N-(benzyloxycarbonyl)aniline

Conditions
ConditionsYield
With sodium hydrogencarbonate In tetrahydrofuran at 0 - 20℃;100%
With sodium hydrogencarbonate In tetrahydrofuran at 0 - 20℃;100%
With sodium hydrogencarbonate In tetrahydrofuran; water at 0℃; for 1h;100%
benzyl chloroformate
501-53-1

benzyl chloroformate

glycine
56-40-6

glycine

N-(Benzyloxycarbonyl)glycine
1138-80-3

N-(Benzyloxycarbonyl)glycine

Conditions
ConditionsYield
With sodium hydroxide In water at 0 - 20℃;100%
With potassium carbonate In tetrahydrofuran; water at 20℃; for 12h;96%
Stage #1: glycine With sodium hydroxide In water Inert atmosphere;
Stage #2: benzyl chloroformate In water at 0℃; for 0.833333h; Inert atmosphere;
95%
benzyl chloroformate
501-53-1

benzyl chloroformate

L-proline
147-85-3

L-proline

N-Benzyloxycarbonyl-L-proline
1148-11-4

N-Benzyloxycarbonyl-L-proline

Conditions
ConditionsYield
With sodium hydroxide In water for 13.5h; Ambient temperature;100%
With sodium carbonate at 0 - 20℃; for 3h;100%
With sodium hydroxide at 0℃; for 0.166667h;97%
benzyl chloroformate
501-53-1

benzyl chloroformate

cis-hydroxy-D-proline
2584-71-6

cis-hydroxy-D-proline

(R,R)-4-hydroxy-1-(benzyloxycarbonyl)pyrrolidine-2-carboxylic acid
130930-25-5

(R,R)-4-hydroxy-1-(benzyloxycarbonyl)pyrrolidine-2-carboxylic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In water; toluene at 20℃; for 16.25h;100%
With sodium hydrogencarbonate In 1,4-dioxane; water100%
With sodium hydrogencarbonate In water; toluene for 16.5h; Ambient temperature;96%
benzyl chloroformate
501-53-1

benzyl chloroformate

4R-4-hydroxyproline
51-35-4

4R-4-hydroxyproline

(2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid
13504-85-3

(2S,4R)-1-(benzyloxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate In diethyl ether Acylation;100%
With sodium hydroxide at 0 - 20℃; for 5h;100%
With sodium hydrogencarbonate In water; toluene at 20℃; for 12.25h;100%
L-tyrosine
60-18-4

L-tyrosine

benzyl chloroformate
501-53-1

benzyl chloroformate

Cbz-Tyr-OH
1164-16-5

Cbz-Tyr-OH

Conditions
ConditionsYield
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 4h; Inert atmosphere; Cooling with ice;100%
With N-ethyl-N,N-diisopropylamine96%
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 12h; Cooling with ice;95%
2-Aminoisobutyric acid
62-57-7

2-Aminoisobutyric acid

benzyl chloroformate
501-53-1

benzyl chloroformate

Z-Aib-OH
15030-72-5

Z-Aib-OH

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water at 20℃; for 20h;100%
With sodium carbonate In 1,4-dioxane; water at 0 - 20℃; for 18h;97%
With hydrogenchloride; sodium hydroxide In 1,4-dioxane; toluene at 0 - 20℃;95%
sarcosine
107-97-1

sarcosine

benzyl chloroformate
501-53-1

benzyl chloroformate

N-(Benzyloxycarbonyl)sarcosine
39608-31-6

N-(Benzyloxycarbonyl)sarcosine

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane; water at 20℃;100%
With sodium carbonate In 1,4-dioxane; water 1.) 0 deg C, 1.5 h, 2.) room temperature, 11 h;99%
With sodium hydroxide In water at 0 - 20℃; for 16h;94%
L-tert-Leucine
20859-02-3

L-tert-Leucine

benzyl chloroformate
501-53-1

benzyl chloroformate

(S)-N-carbobenzoxy-tert-butylleucine
62965-10-0

(S)-N-carbobenzoxy-tert-butylleucine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0℃; for 18h;100%
With sodium hydroxide In water for 3h; Inert atmosphere;100%
With sodium hydroxide In water at 5 - 20℃; for 14h; pH=10 - 10.5; Product distribution / selectivity;97%
1-methyl-1-tert-butoxycarbonylhydrazine
21075-83-2

1-methyl-1-tert-butoxycarbonylhydrazine

benzyl chloroformate
501-53-1

benzyl chloroformate

2-benzyl 1-tert-butyl 1-methylhydrazine-1,2-dicarboxylate
57699-92-0

2-benzyl 1-tert-butyl 1-methylhydrazine-1,2-dicarboxylate

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethyl acetate at 0 - 1℃; for 1h;100%
With sodium hydroxide In dichloromethane; water at 20℃; for 2h;81%
With sodium hydroxide In 1,4-dioxane; water at 25℃; for 1h;69.54%
methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride
5680-80-8

methyl (2S)-2-amino-3-hydroxypropanoate hydrochloride

benzyl chloroformate
501-53-1

benzyl chloroformate

N-benzyloxycarbonyl-L-serine methyl ester
1676-81-9

N-benzyloxycarbonyl-L-serine methyl ester

Conditions
ConditionsYield
With potassium carbonate In tetrahydrofuran; water 0 deg C -> room temperature, 4 h;100%
With sodium hydrogencarbonate In dichloromethane; water at 0 - 20℃; for 6h;97%
With sodium hydrogencarbonate93%
methyl 2-amino-3-hydroxypropanoate hydrochloride
5619-04-5

methyl 2-amino-3-hydroxypropanoate hydrochloride

benzyl chloroformate
501-53-1

benzyl chloroformate

methyl 2-(benzyloxycarbonylamino)-3-hydroxypropanoate
14464-15-4

methyl 2-(benzyloxycarbonylamino)-3-hydroxypropanoate

Conditions
ConditionsYield
With sodium carbonate In tetrahydrofuran at 20℃; for 12h;100%
Stage #1: methyl 2-amino-3-hydroxypropanoate hydrochloride; benzyl chloroformate With sodium hydrogencarbonate In water at 0 - 20℃; for 24.75h; Inert atmosphere;
Stage #2: With hydrogenchloride In water pH=1;
75%
With triethylamine In dichloromethane for 5h; Ambient temperature;70%
benzyl chloroformate
501-53-1

benzyl chloroformate

ethylenediamine
107-15-3

ethylenediamine

1,2-Ethanediylbis(phenylmethyl carbamate)
18807-67-5

1,2-Ethanediylbis(phenylmethyl carbamate)

Conditions
ConditionsYield
With potassium hydroxide100%
With sodium hydroxide
benzyl chloroformate
501-53-1

benzyl chloroformate

3-amino-2-propanol
78-96-6, 1674-56-2

3-amino-2-propanol

1-Benzyloxycarbonylamino-2,4-propanediol
65935-10-6

1-Benzyloxycarbonylamino-2,4-propanediol

Conditions
ConditionsYield
With sodium carbonate In water at 0℃; for 3h;100%
With sodium carbonate In water at 0℃; for 3h;100%
With sodium carbonate In water at 0℃; for 3h;96%
pyridine
110-86-1

pyridine

benzyl chloroformate
501-53-1

benzyl chloroformate

N-benzyloxycarbonyl-1,2-dihydropyridine
79328-85-1

N-benzyloxycarbonyl-1,2-dihydropyridine

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at -65℃; for 1h;100%
With sodium tetrahydroborate In methanol at -75℃; for 3h;96%
With sodium tetrahydroborate In ethanol at -78℃; for 1.5h;74%
1,2,3,6-tetrahydropyridine
694-05-3

1,2,3,6-tetrahydropyridine

benzyl chloroformate
501-53-1

benzyl chloroformate

1-benzyloxycarbonyl-1,2,3,6-tetrahydropyridine
66207-23-6

1-benzyloxycarbonyl-1,2,3,6-tetrahydropyridine

Conditions
ConditionsYield
With triethylamine In dichloromethane at 20℃; for 16h;100%
With sodium carbonate at 0℃; for 2h;99%
With sodium carbonate In water at 5 - 20℃; Cooling with ice;99%
2-pyrrolidinon
616-45-5

2-pyrrolidinon

benzyl chloroformate
501-53-1

benzyl chloroformate

N-benzyloxycarbonylpyrrolidin-2-one
14468-80-5

N-benzyloxycarbonylpyrrolidin-2-one

Conditions
ConditionsYield
Stage #1: 2-pyrrolidinon With n-butyllithium In tetrahydrofuran
Stage #2: benzyl chloroformate In tetrahydrofuran
100%
Stage #1: 2-pyrrolidinon With sodium hydroxide In toluene for 6h; Dean-Stark; Reflux;
Stage #2: benzyl chloroformate In toluene at 5 - 12℃; for 2h;
95.2%
Stage #1: 2-pyrrolidinon With lithium hexamethyldisilazane In tetrahydrofuran at -78℃; for 0.5h; Inert atmosphere;
Stage #2: benzyl chloroformate In tetrahydrofuran at -78 - -40℃; for 3h; Inert atmosphere;
91%
isonipecotic acid
498-94-2

isonipecotic acid

benzyl chloroformate
501-53-1

benzyl chloroformate

1-benzyloxycarbonylpiperidine-4-carboxylic acid
10314-98-4

1-benzyloxycarbonylpiperidine-4-carboxylic acid

Conditions
ConditionsYield
With sodium hydrogencarbonate; sodium carbonate In water; acetonitrile at 0 - 20℃; for 2h; pH=10 - 11;100%
With potassium carbonate In water at 22℃; for 58h;97%
With sodium hydrogencarbonate In tetrahydrofuran; water at 0 - 20℃;96%
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