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Cas:75-44-5
Min.Order:10 Milligram
Negotiable
Type:Lab/Research institutions
inquiryConditions | Yield |
---|---|
With catalyst: charcoal in laboratorium, at ambient temp., in a glas tube filled with charcoal; | 100% |
pyrographite at 40 - 85℃; under 1050.11 - 5250.53 Torr; Product distribution / selectivity; Continuous process; | |
pyrographite at 45 - 93.5℃; under 1500.15 - 3750.38 Torr; Shell-and-tube reactor; |
bis(trichloromethyl) carbonate
A
tetrachloromethane
B
phosgene
C
carbon dioxide
Conditions | Yield |
---|---|
With copper phthalocyanine at 90℃; for 0.583333h; Mechanism; Reagent/catalyst; Temperature; Time; | A n/a B 100% C n/a |
2,2,3,3,4,4,5,5-octafluoropentan-1-ol
bis(trichloromethyl) carbonate
A
phosgene
B
2,2,3,3,4,4,5,5-octafluoropentyl chloroformate
C
bis(2,2,3,3,4,4,5,5-octafluoropentyl) carbonate
Conditions | Yield |
---|---|
Stage #1: bis(trichloromethyl) carbonate With pyridine In pentane at -15℃; for 1h; Stage #2: 2,2,3,3,4,4,5,5-octafluoropentan-1-ol In pentane at -15℃; for 6h; | A n/a B 95% C 5% |
bis(trichloromethyl) carbonate
(2,3,4,5,6-pentafluorophenyl)methanol
A
phosgene
B
2,3,4,5,6-pentafluorobenzyl chloroformate
Conditions | Yield |
---|---|
Stage #1: bis(trichloromethyl) carbonate With pyridine In pentane at -15℃; for 1h; Stage #2: (2,3,4,5,6-pentafluorophenyl)methanol In pentane at -15 - 0℃; for 6h; | A n/a B 92% C 8% |
Conditions | Yield |
---|---|
With water; antimony(V) chloride In water reaction at 60°C on addn. of 0.1 mol SbCl5;; | 90% |
With water; Gallium trichloride In water reaction at 60°C on addn. of 0.1 mol GaCl3;; | 89% |
With air; fired clay fragments |
bis(trichloromethyl) carbonate
2-(pentafluorophenoxy)ethanol
A
phosgene
Conditions | Yield |
---|---|
Stage #1: bis(trichloromethyl) carbonate With pyridine In pentane at -15℃; for 1h; Stage #2: 2-(pentafluorophenoxy)ethanol In pentane at -15 - 20℃; for 6h; | A n/a B 86% C 11% |
tert-butyl 2-bromopropionate
ethylene dibromide
phosgene
Conditions | Yield |
---|---|
With chloro-trimethyl-silane; ammonium chloride In tetrahydrofuran | 73% |
Conditions | Yield |
---|---|
With sulfur dioxide In neat (no solvent) reaction of CCl4 with SO2 on heating to 200°C;; | A n/a B 72% |
Conditions | Yield |
---|---|
With CO In thionyl chloride AuCl3 suspended in SOCl2 under N2, reaction flask evacuated, filled with CO at atm. pressure, stirred at 20.1°C until Au2Cl6 disappeared(36 h); filtration, drying in vac.; | A n/a B 67% |
Conditions | Yield |
---|---|
With chloro-trimethyl-silane In tetrahydrofuran | 63% |
oxalyl dichloride
ethanedinitrile
A
phosgene
B
carbon dioxide
C
2,3,7,8-tetrachloro-5H,10H-diimidazo<1,2-a:1',2'-d>pyrazine-5,10-dione
Conditions | Yield |
---|---|
With hydrogenchloride; hydrogenchloride; NR4Cl (Adogen) In dichloromethane at 70 - 120℃; for 72h; Further byproducts given; | A n/a B n/a C 60% |
iron pentacarbonyl
phosgene
Conditions | Yield |
---|---|
With tetrachloromethane; oxygen In tetrachloromethane Irradiation (UV/VIS); Irradiation λ >350 nm, CCl4 satd. with dry air;; detected by IR sepctra;; | 50% |
Conditions | Yield |
---|---|
In neat (no solvent) condensing HCl onto N,N'-carbonyldiimidazole at -196°C, warming to -63°C, condensing excess HCl into a trap held at -196°C; contains some HCl; | 49.8% |
Conditions | Yield |
---|---|
In dichloromethane N2-atmosphere; slight molar excess of Au(I), 1.5 h; | A n/a B 42% |
In thionyl chloride N2-atmosphere; molar ratio Au(III):Au(I)=3:1 to 1:1, 3-28 h; filtration (under Ar), drying (vac.); elem. anal.; yield depending on molar ratio of educts, amt. of solvent and reaction time; | A n/a B 24% |
tetrafluorohydrazine
oxalyl dichloride
A
phosgene
B
chlorodifluoroamine
C
dinitrogen difluoride
D
fluoroformyl chloride
E
difluorocarbamoyl chloride
Conditions | Yield |
---|---|
other Radiation; UV photolysis, 6h, ratio of educts: (ClCO)2 112 Torr, N2F4 168 Torr; fractionated condensation, gaschromy.; | A n/a B n/a C n/a D n/a E 40% |
other Radiation; UV photolysis, 6h, ratio of educts: (ClCO)2 112 Torr, N2F4 168 Torr; fractionated condensation, gaschromy.; | A n/a B n/a C n/a D n/a E 40% |
perfluoro(N,N-diethylcarbamoyl fluoride)
A
tetrachloromethane
B
phosgene
Conditions | Yield |
---|---|
With aluminium trichloride at 100℃; for 100h; | A 0.03 g B 0.02 g C 38.7% |
Conditions | Yield |
---|---|
With chlorine at 510 - 700℃; | A 35% B n/a |
Conditions | Yield |
---|---|
Irradiation (UV/VIS); with Cl2 sensibilized photochemical oxidn., 80 to 100°C; | A 20% B n/a |
Chlorodifluoromethane
A
phosgene
B
Carbonyl fluoride
C
fluoroformyl chloride
Conditions | Yield |
---|---|
With oxygen for 0.5 - 4.5h; Product distribution / selectivity; UV-irradiation (500 W); | A 0.04% B 15.6% C 0.24% |
pyridine
bis(trichloromethyl) oxalate
chlorobenzene
A
phosgene
B
oxalyl dichloride
Conditions | Yield |
---|---|
With chlorine monoxide |
Conditions | Yield |
---|---|
With aluminium trichloride |
Conditions | Yield |
---|---|
With aluminium trichloride |
tetrachloromethane
(4-nitro-phenyl)-carbamic acid trichloromethyl ester
A
phosgene
B
4-Nitrophenyl isocyanate
tetrachloromethane
methylammonium carbonate
phosgene
Conditions | Yield |
---|---|
With pumice stone at 350℃; |
tetrachloromethane
A
phosgene
B
methylammonium carbonate
Conditions | Yield |
---|---|
With zinc(II) oxide at 200℃; |
Conditions | Yield |
---|---|
With ozone | |
In gas byproducts: Cl; Irradiation (UV/VIS); with Cl2 sensibilized photochemical oxidn.; |
phosgene
Conditions | Yield |
---|---|
bei laengerem Aufbewahren; |
Conditions | Yield |
---|---|
With air | |
With oxygen | |
an der Luft; |
Conditions | Yield |
---|---|
With N-ethyl-N,N-diisopropylamine In dichloromethane at 0℃; for 3h; Inert atmosphere; | 100% |
With triethylamine In tetrahydrofuran at 0℃; | 74% |
Conditions | Yield |
---|---|
In tetrahydrofuran at 40℃; for 1.5h; | 100% |
In tetrahydrofuran at 40℃; for 5h; | 99.7% |
In tetrahydrofuran; toluene at 50 - 60℃; for 4h; | 96% |
phosgene
2-(4-nitrophenyl)ethanol
2-(4-nitrophenyl)ethoxycarbonyl chloride
Conditions | Yield |
---|---|
In dichloromethane; toluene 1.) r.t., 1 h; 2.) 50 deg C, 5 h; | 100% |
In dichloromethane; toluene for 1h; Ambient temperature; | 98% |
phosgene
2,4,6-tri-tert-butylphenoxol
2,4,6-tri(tert-butyl)phenyl carbonochloridate
Conditions | Yield |
---|---|
With n-butyllithium at 0℃; | 100% |
With n-butyllithium In 1,2-dimethoxyethane at 0℃; | 98% |
Stage #1: 2,4,6-tri-tert-butylphenoxol With sodium hydride In tetrahydrofuran Metallation; Stage #2: phosgene With N,N-dimethyl-aniline In toluene at 0 - 20℃; for 2.5h; Acylation; | 75% |
Conditions | Yield |
---|---|
In tetrahydrofuran; toluene at 20℃; for 18h; | 100% |
In tetrahydrofuran; toluene for 21h; Esterification; | 99% |
In 1,4-dioxane for 24h; Ambient temperature; |
Conditions | Yield |
---|---|
With pyridine In chloroform at 23℃; for 17h; | 100% |
phosgene
(2S,3R,4S)-1-amino-4-<<(tertbutyloxy)carbonyl>amino>-5-cyclohexyl-2-hydroxy-3-(methoxymethoxy)pentane
(1'R,2'S,5S)-5-<2'-<<(tertbutyloxy)carbonyl>amino>-3'-cyclohexyl-1'-(methoxymethoxy)propyl>oxazolidin-2-one
Conditions | Yield |
---|---|
With triethylamine In dichloromethane; toluene 1.) a) 0 deg C, 1 h, b) RT, 1 h; | 100% |
phosgene
(-)-8-phenylmenthol
(1R,2S,5R)-(-)-8-phenylmenthyl chloroformate
Conditions | Yield |
---|---|
With quinoline In toluene for 16h; Ambient temperature; | 100% |
With quinoline In toluene at 0 - 20℃; for 16.5h; | |
With quinoline In toluene at 0 - 20℃; for 16.5h; |
phosgene
2-(1-methyl-1-p-phenoxyphenylethyl)-5-methylcyclohexanol
(1R,2S,5R)-8-(4-phenoxyphenyl)menthyl chloroformate
Conditions | Yield |
---|---|
With quinoline In toluene for 16h; Ambient temperature; | 100% |
phosgene
methyl 4-(2-hydroxyethyl)-3-nitrobenzoate
2-(4-(methoxycarbonyl)-2-nitrophenyl)ethyl chloroformate
Conditions | Yield |
---|---|
100% | |
In dichloromethane; toluene a) 4 deg C, 30 min, b) room temperature, 3 h; | 87% |
phosgene
2,4,5-Trichlorophenyl 4'-(2-hydroxyethyl)-3'-nitrobenzoate
C16H9Cl4NO6
Conditions | Yield |
---|---|
100% | |
In dichloromethane; toluene a) 4 deg C, 30 min., b) room temperature, 3 h; | 92% |
phosgene
2-Oxa-3-azabicyclo<2.2.2>oct-5-ene hydrochloride
Conditions | Yield |
---|---|
With triethylamine In dichloromethane for 12h; | 100% |
phosgene
[1-Phenyl-1-(3H-[1,2,3]triazol-4-yl)-meth-(Z)-ylidene]-hydrazine
4-phenyl-6H-<1,2,3>triazolo<1,5-d><1,2,4>triazin-7-one
Conditions | Yield |
---|---|
In 1,4-dioxane; toluene for 5h; Ambient temperature; | 100% |
phosgene
N-(pyridin-2-yl)-1H-benzo[d]imidazol-2-amine
Conditions | Yield |
---|---|
With triethylamine In toluene for 6h; Ambient temperature; | 100% |
Conditions | Yield |
---|---|
With pyridine In toluene at 0℃; for 1h; | 100% |
Conditions | Yield |
---|---|
In ethyl acetate at 45℃; | 100% |
phosgene
(2S,3S)-Dimethyl N-(9'-phenylfluoren-9'-yl)-3-hydroxyaspartate
(4S,5S)-2-Oxo-3-(9-phenyl-9H-fluoren-9-yl)-oxazolidine-4,5-dicarboxylic acid dimethyl ester
Conditions | Yield |
---|---|
With pyridine; dmap In toluene at 75℃; for 0.416667h; | 100% |
phosgene
(Z)-(R)-9-Benzylamino-3,4,5,6,9,10-hexahydro-thiecin-2-one
Conditions | Yield |
---|---|
With 1,8-diazabicyclo[5.4.0]undec-7-ene In dichloromethane at 0℃; for 3.5h; | 100% |
phosgene
(4S,5S)-4-[(3R,3aR,5aS,6R,7R,9aS,9bS)-6-(2,2-Dimethoxy-ethyl)-3-((R)-1,5-dimethyl-hexyl)-3a,6-dimethyl-dodecahydro-cyclopenta[a]naphthalen-7-yl]-6,6,8-trimethyl-1,3-dioxa-spiro[4.5]decane-2,7-dione
Conditions | Yield |
---|---|
With pyridine In dichloromethane at 0℃; | 100% |
With pyridine In dichloromethane at 0℃; Yield given; |
phosgene
Conditions | Yield |
---|---|
In dichloromethane; toluene at 0℃; for 3h; | 100% |
phosgene
12,14-diaminodehydroabietic acid methyl ester
(1R,4aS,10aR)-6,8-Diisocyanato-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydro-phenanthrene-1-carboxylic acid methyl ester
Conditions | Yield |
---|---|
In toluene for 0.5h; Ambient temperature; | 100% |
2,3;4,5-di-O-isopropylidene-β-D-fructopyranose
phosgene
2,3:4,5-di-O-isopropylidene-β-D-fructopyranose-10-chloroformate
Conditions | Yield |
---|---|
In diethyl ether; toluene Ambient temperature; | 100% |
phosgene
2-[(1,1,2,2-tetramethyl-1-silapropoxy)methyl]phenylamine
tert-butyl(2-isocyanatobenzyloxy)dimethylsilane
Conditions | Yield |
---|---|
In toluene at 110℃; | 100% |
In toluene at 60℃; for 1h; |
phosgene
(2-Cyano-ethyl)-(2-phenylamino-ethyl)-carbamic acid tert-butyl ester
C17H22ClN3O3
Conditions | Yield |
---|---|
With sodium hydrogencarbonate In dichloromethane; water; toluene for 0.5h; Acylation; | 100% |
phosgene
Conditions | Yield |
---|---|
With TEA In dichloromethane | 100% |
phosgene
Conditions | Yield |
---|---|
With TEA In dichloromethane | 100% |
phosgene
(9H-fluoren-9-yl)methyl1-methylhydrazinecarboxylate
2-(chlorocarbonyl)-1-Fmoc-methylhydrazine
Conditions | Yield |
---|---|
In 1,4-dioxane at 10 - 20℃; Acylation; | 100% |
phosgene
(9H-fluoren-9-yl)methyl 2-methylhydrazine-1-carboxylate
1-chlorocarbonyl-2-(9H-fluoren-9-methoxycarbonylamino)-1-methylhydrazine
Conditions | Yield |
---|---|
In 1,4-dioxane at 10 - 20℃; Acylation; | 100% |
With sodium hydrogencarbonate In dichloromethane; water for 0.5h; | 97% |
With sodium hydrogencarbonate In dichloromethane; water; toluene for 0.5h; | 97% |
In 1,4-dioxane; toluene at 20℃; for 2h; | |
In dichloromethane; toluene at 0℃; |
Conditions | Yield |
---|---|
With pyridine In diethyl ether; toluene at -78 - 20℃; Acylation; | 100% |
phosgene
[2,7-di-(tert-butyl)-9H-fluoren-9-yl]methanol
2,7-di-tert-butyl-9-fluorenylmethoxycarbonyl chloride
Conditions | Yield |
---|---|
In dichloromethane; toluene at 20℃; for 72h; chloroacylation; | 100% |
In toluene |