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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

Ethyl 2-chloroacetoacetate Manufacturer/High quality/Best price/In stock

Cas:609-15-4

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2-Chloroacetoacetate supplier in China

Cas:609-15-4

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Factory supply Ethyl 2-chloroacetoacetate CAS 609-15-4 with fast delivery Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/

Factory supply Ethyl 2-chloroacetoacetate CAS 609-15-4 with fast delivery

Cas:609-15-4

Min.Order:10 Kilogram

FOB Price: $10.0

Type:Trading Company

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Hefei TNJ chemical industry co.,ltd

ISO Certification Technology: Technology innovation is our eternal pursuit,or we will be left behind.Our technology experts,all from famous universities and institutes,has rich experience and high achievements in chemical research.This makes sure

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Henan Allgreen Chemical Co.,Ltd

high quality Appearance:White or off-white Solid Storage:Sealed, dry, microtherm , avoid light and smell. Package:According to the demand of customer Application:Organic synthesis Transportation:by air or by sea Port:shanghai

Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Oled CAS 609-15-4 Butanoicacid, 2-chloro-3-oxo-, ethyl ester

Cas:609-15-4

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

2-Chloroacetoacetic acid ethyl ester

Cas:609-15-4

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

Ethyl 2-chloroacetoacetate / LIDE PHARMA- Factory supply / Best price

Cas:609-15-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Henan Tianfu Chemical Co., Ltd.

Ethyl 2-chloroacetoacetate Basic information Product Name: Ethyl 2-chloroacetoacetate Synonyms: 2-CHLOROACETOACETIC ACID ETHYL ESTER;2-CL-ACE;A-CHLOROACETOACETIC ESTER;AKOS BBS-00004302;

TIANFU-CHEM CAS:609-15-4 Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

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Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Manufacturer supply CAS 609-15-4 with best quality

Cas:609-15-4

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Product Name: Ethyl 2-chloroacetoacetate CAS NO.: 609-15-4 Molecular Formula: C6H9ClO3 Structural Formula: Appearance: oil liquid Purity: 99% Package: 2

Ethyl 2-chloroacetoacetate CAS: 609-15-4

Cas:609-15-4

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Butanoicacid, 2-chloro-3-oxo-, ethyl ester 609-15-4

Cas:609-15-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Hangzhou Sartort Biopharma Co., Ltd

Appearance:clear bright yellow liquid Storage:Room temperature Package:190kg/Barrel Application:Pharmaceutical intermediates Transportation:Express/Sea/Air Port:Any port in china

High quality Ethyl 2-chloroacetoacetate supplier in China

Cas:609-15-4

Min.Order:190 Kilogram

Negotiable

Type:Lab/Research institutions

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Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1 Kilogram

FOB Price: $88.0 / 100.0

Type:Trading Company

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Qingdao Beluga Import and Export Co., LTD

Ethyl 2-chloroacetoacetate CAS:609-15-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic

Ethyl 2-chloroacetoacetate CAS:609-15-4

Cas:609-15-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

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Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Butanoicacid, 2-chloro-3-oxo-, ethyl ester

Cas:609-15-4

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

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Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:609-15-4

Cas:609-15-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

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Hebei Mojin Biotechnology Co.,Ltd

Hebei Mojin Biotechnology Co., Ltd, Our company is a professional chemical raw materials and chemical reagents research and development production enterprises. We have several production line,So we can control the lowest price. We also have several

Ethyl 2-Chloroacetoacetate cas:609-15-4

Cas:609-15-4

Min.Order:25 Gram

FOB Price: $90.0 / 100.0

Type:Trading Company

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Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2-Chloroacetoacetate

Cas:609-15-4

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Lorcaserin(856681-05-5)is an orally administered agent and a selective 5-HT2C receptor agonist for the treatment of obesity. It had been approved for marketing in US by FDA on 27 June in 2012. In clinical studies, lorcaserin h

Ethyl 2-chloroacetoacetate 609-15-4

Cas:609-15-4

Min.Order:100 Metric Ton

Negotiable

Type:Lab/Research institutions

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Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

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Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

ETHYL 2-CHLOROACETOACETATE

Cas:609-15-4

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Shaanxi Cuicheng Biomedical Technology Co., Ltd.

Why Choose Us: 1. Factory direct sales, so we can provide the competitive price and high quality product base on 8 years of production and R&D experience. 2. It is available in stock for quick shipment.Products could be packaged according to cu

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1 Gram

Negotiable

Type:Other

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Shanghai Massive Chemical Technology Co., Ltd.

Massive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:1 Gram

FOB Price: $1.0

Type:Lab/Research institutions

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2-Chloroacetoacetate

Cas:609-15-4

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

Ethyl 2-chloroacetoacetate

Cas:609-15-4

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

Synthetic route

ethyl acetoacetate
141-97-9

ethyl acetoacetate

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With thionyl chloride In tetrachloromethane at 20℃; for 1h;100%
With sulfuryl dichloride In dichloromethane at 0 - 20℃;98.4%
With sulfuryl dichloride In tetrachloromethane at 20℃; for 1h;97%
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2,2-dichloroacetoacetate
6134-66-3

ethyl 2,2-dichloroacetoacetate

B

ethyl 2,2,4-trichloro-3-oxobutyrate
85153-67-9

ethyl 2,2,4-trichloro-3-oxobutyrate

C

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With chlorine at 55 - 60℃; for 9h; Product distribution; Mechanism; dinamics of chlorination of acetoacetic ester, products in the mixture on the time;A 97%
B n/a
C n/a
With chlorine at 55 - 60℃;A 97%
B n/a
C n/a
With hydrogenchloride; sodium chloride at 22 - 25℃; for 8.5h; electrolysis, ruthenium-titanum oxide anode, current 7 A;A 92%
B 3%
C n/a
ethyl 3-oxobutanate sodium salt
20412-62-8, 66279-49-0

ethyl 3-oxobutanate sodium salt

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With tetrachloromethane In dimethyl sulfoxide for 16h; Heating; at 20 - 25 deg C in different bipolar aprotic solvents;46%
4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

ethanol
64-17-5

ethanol

chloroform
67-66-3

chloroform

acetic acid-(2,4,N-trichloro-anilide)
112160-74-4

acetic acid-(2,4,N-trichloro-anilide)

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

4-methyleneoxetan-2-one
674-82-8

4-methyleneoxetan-2-one

ethanol
64-17-5

ethanol

acetic acid-(2,4,N-trichloro-anilide)
112160-74-4

acetic acid-(2,4,N-trichloro-anilide)

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With chloroform
diethyl ether
60-29-7

diethyl ether

ethyl chlorosulfate
625-01-4

ethyl chlorosulfate

sodium ethyl acetylacetate enolate
1007476-32-5

sodium ethyl acetylacetate enolate

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

diethyl ether
60-29-7

diethyl ether

ethyl chlorosulfate
625-01-4

ethyl chlorosulfate

sodium ethyl acetylacetate enolate
1007476-32-5

sodium ethyl acetylacetate enolate

A

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

B

Diethyl 2,3-diacetylsuccinate
2049-86-7

Diethyl 2,3-diacetylsuccinate

2-chloro-3-oxobutanenitrile
60930-76-9

2-chloro-3-oxobutanenitrile

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With sulfuric acid anschliessend mit H2O;
sodium ethyl acetylacetate enolate
1007476-32-5

sodium ethyl acetylacetate enolate

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

phosgene
75-44-5

phosgene

sodium ethyl acetylacetate enolate
1007476-32-5

sodium ethyl acetylacetate enolate

benzene
71-43-2

benzene

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

(E)-2-Chloro-3-hydroxy-but-2-enoic acid ethyl ester
115538-75-5

(E)-2-Chloro-3-hydroxy-but-2-enoic acid ethyl ester

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With (enolisation) In methanol Equilibrium constant; other solvents;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

diethyl acetylsuccinate
1115-30-6

diethyl acetylsuccinate

B

ethyl 3-chloropropanoate
623-71-2

ethyl 3-chloropropanoate

C

acetic acid
64-19-7

acetic acid

D

ethyl acetate
141-78-6

ethyl acetate

E

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

F

succinic acid diethyl ester
123-25-1

succinic acid diethyl ester

Conditions
ConditionsYield
With dihydrogen peroxide; iron(II) chloride Product distribution; multistep reaction; 1.) H2O2, 20 deg C, 2 h; other Fe(II) salts (FeSO4*7H2O, FeSO4-CuSO4), decomposition of the peroxides of the esters of keto acids by Fe(II) salts, possible scheme of decomposition;A 0.05 mol
B 0.10 mol
C 0.27 mol
D 0.11 mol
E 0.06 mol
F n/a
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2,2-dichloroacetoacetate
6134-66-3

ethyl 2,2-dichloroacetoacetate

B

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

C

ethyl 2-hydroxyimino-3-oxobutanoate
5408-04-8

ethyl 2-hydroxyimino-3-oxobutanoate

Conditions
ConditionsYield
With Nitryl chloride In dichloromethane at 20℃; for 2h; Product distribution; variation of molar ratio of NO2Cl/educt, solvent, temperature and add. of CaCl2 or Na2SO4;A 11 % Chromat.
B 30 % Chromat.
C 57 % Chromat.
ethyl acetoacetate
141-97-9

ethyl acetoacetate

chlorine
7782-50-5

chlorine

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl acetoacetate
141-97-9

ethyl acetoacetate

sulfuryl chloride (1 mol)

sulfuryl chloride (1 mol)

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

β--butyric acid ester

β--butyric acid ester

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With sulfuric acid
copper acetoacetic acid ester

copper acetoacetic acid ester

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With chloroform; chlorine
3-chloroamino-crotonic acid ethyl ester

3-chloroamino-crotonic acid ethyl ester

sulfuric acid
7664-93-9

sulfuric acid

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
Destillation;
ethyl 2-iodo-3-oxobutanoate
104690-31-5

ethyl 2-iodo-3-oxobutanoate

silver chloride

silver chloride

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

chloroform
67-66-3

chloroform

copper(II) ethyl acetoacetate

copper(II) ethyl acetoacetate

chlorine
7782-50-5

chlorine

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl acetate
141-78-6

ethyl acetate

chloroacetic acid ethyl ester
105-39-5

chloroacetic acid ethyl ester

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With lithium diisopropyl amide In tetrahydrofuran at -78℃;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2,4-dichloro-3-oxobutanoate
88-00-6

ethyl 2,4-dichloro-3-oxobutanoate

B

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With chlorine at 35℃; under 750.075 Torr; for 10h; Product distribution / selectivity;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

methyl 2-chloroacetoacetate
4755-81-1

methyl 2-chloroacetoacetate

B

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With 1,3-dichloro-5,5-dimethylhydantoin; silica gel In methanol for 1h; Reflux;
ethyl acetoacetate
141-97-9

ethyl acetoacetate

A

ethyl 2,2-dichloroacetoacetate
6134-66-3

ethyl 2,2-dichloroacetoacetate

B

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With potassium peroxymonosulfate; ammonium chloride In methanol at 20℃; for 6h;A 12 %Chromat.
B 66 %Chromat.
With chloro-trimethyl-silane; [bis(acetoxy)iodo]benzene In acetonitrile at 20℃; for 2h;
ethanol
64-17-5

ethanol

2-chloro-3-oxobutanoic acid
5819-34-1

2-chloro-3-oxobutanoic acid

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

Conditions
ConditionsYield
With toluene-4-sulfonic acid In toluene for 2h; Reflux;
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

recorcinol
108-46-3

recorcinol

3-chloro-4-methylumbelliferone
6174-86-3

3-chloro-4-methylumbelliferone

Conditions
ConditionsYield
With trifluoroacetic acid at 100℃; for 0.5h; Pechmann condensation; Microwave irradiation; regioselective reaction;100%
With zirconium(IV) oxychloride In ethanol at 60 - 65℃; for 24h; Pechmann reaction;98%
With aluminum potassium sulfate dodecahydrate at 65℃; for 2h; Pechmann condensation; Neat (no solvent);93%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl 3-hydroxybutyrate
5405-41-4

ethyl 3-hydroxybutyrate

Conditions
ConditionsYield
In water for 2h; baker's yeast;100%
3-(trifluoromethyl)benzothioamide
53515-17-6

3-(trifluoromethyl)benzothioamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

4-methyl-2-[3-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid ethyl ester
144061-14-3

4-methyl-2-[3-(trifluoromethyl)phenyl]thiazole-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
In ethanol at 80℃;100%
In ethanol for 24h; Heating;
4-ethoxy-2-fluoroaniline
470702-37-5

4-ethoxy-2-fluoroaniline

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

(Z)-ethyl 2-chloro-2-(2-(4-ethoxy-2-fluorophenyl)hydrazono)acetate

(Z)-ethyl 2-chloro-2-(2-(4-ethoxy-2-fluorophenyl)hydrazono)acetate

Conditions
ConditionsYield
Stage #1: 4-ethoxy-2-fluoroaniline With hydrogenchloride; sodium nitrite In ethanol; water at 0℃; for 0.333333h;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at 20℃; for 2h;
100%
Stage #1: 4-ethoxy-2-fluoroaniline With hydrogenchloride; sodium nitrite In ethanol; water at 0℃; for 0.333333h;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at 0 - 20℃; for 2h;
100%
Stage #1: 4-ethoxy-2-fluoroaniline With hydrogenchloride; sodium nitrite In ethanol; water at 0℃; for 0.333333h;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at 20℃; for 2h;
100%
1-(methyl)-thiourea
598-52-7

1-(methyl)-thiourea

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

4-methyl-2-(methylamino)thiazole-5-carboxylic acid ethyl ester
3161-68-0

4-methyl-2-(methylamino)thiazole-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
With sodium hydrogencarbonate In neat (no solvent) at 75℃; for 0.333333h;99%
With pyridine In methanol at 20℃; for 4h;85%
With dmap In dichloromethane at 20℃; for 4h;85%
Benzimidazol-2-thiol
134469-07-1

Benzimidazol-2-thiol

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl 2-(1H-1,3-benzodiazol-2-ylsulfanyl)-3-oxobutanoate
5268-66-6

ethyl 2-(1H-1,3-benzodiazol-2-ylsulfanyl)-3-oxobutanoate

Conditions
ConditionsYield
With sodium hydrogencarbonate In ethanol at 20℃; for 5h;99%
With triethylamine In dichloromethane Ambient temperature;
With TEA In ethanol at 20℃; for 5h;
(Z)-2-(2-oxoindolin-3-ylidene)-N-phenylhydrazine-1-carbothioamide
101306-61-0, 28492-94-6

(Z)-2-(2-oxoindolin-3-ylidene)-N-phenylhydrazine-1-carbothioamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

4-Methyl-2-{[2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazono}-3-phenyl-2,3-dihydro-thiazole-5-carboxylic acid

4-Methyl-2-{[2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazono}-3-phenyl-2,3-dihydro-thiazole-5-carboxylic acid

Conditions
ConditionsYield
With sodium acetate In ethanol for 4h; Heating;99%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

(Z)-N-(4-chlorophenyl)-2-(2-oxoindolin-3-ylidene)hydrazine-1-carbothioamide
79560-71-7

(Z)-N-(4-chlorophenyl)-2-(2-oxoindolin-3-ylidene)hydrazine-1-carbothioamide

3-(4-Chloro-phenyl)-4-methyl-2-{[2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazono}-2,3-dihydro-thiazole-5-carboxylic acid

3-(4-Chloro-phenyl)-4-methyl-2-{[2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazono}-2,3-dihydro-thiazole-5-carboxylic acid

Conditions
ConditionsYield
With sodium acetate In ethanol for 4h; Heating;99%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

3-methoxyphenylthioacetamide
35582-11-7

3-methoxyphenylthioacetamide

ethyl 2-(3-methoxybenzyl)-4-methyl-1,3-thiazole-5-carboxylate
1318758-22-3

ethyl 2-(3-methoxybenzyl)-4-methyl-1,3-thiazole-5-carboxylate

Conditions
ConditionsYield
With pyridine In ethanol at 60℃; for 18h;99%
thiourea
17356-08-0

thiourea

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl-2-amino-4-methylthiazole-5-carboxylate
7210-76-6

ethyl-2-amino-4-methylthiazole-5-carboxylate

Conditions
ConditionsYield
With sodium carbonate In ethanol; ethyl acetate at 45 - 65℃; Temperature;98.39%
In ethanol at 20 - 80℃;91%
In ethanol Reflux;91.4%
aniline
62-53-3

aniline

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl (E)-2-chloro-3-(phenylamino)but-2-enoate
31750-57-9

ethyl (E)-2-chloro-3-(phenylamino)but-2-enoate

Conditions
ConditionsYield
With vanadium(III) chloride at 20℃; for 5h;98%
With zinc(II) perchlorate; magnesium sulfate In dichloromethane at 20℃; for 28h;95%
With iron(III) trifluoromethanesulfonate In neat (no solvent) at 20℃;72%
In benzene Heating;
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-3-hydroxypyrazole
329076-65-5

4-(4-fluorophenyl)-5-(4-methylsulfonylphenyl)-3-hydroxypyrazole

ethyl 2-{(4-(4-fluorophenyl)-5-(4-(methylsulphonyl) phenyl)-1H-pyrazol-3-yl]oxy}-3-oxobutanoate
329076-76-8

ethyl 2-{(4-(4-fluorophenyl)-5-(4-(methylsulphonyl) phenyl)-1H-pyrazol-3-yl]oxy}-3-oxobutanoate

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 0 - 20℃;98%
With potassium carbonate In N,N-dimethyl-formamide at 0 - 20℃; for 9h;450 mg
aniline
62-53-3

aniline

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl chloro(2-phenylhydrazono)acetate
28663-68-5

ethyl chloro(2-phenylhydrazono)acetate

Conditions
ConditionsYield
Stage #1: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol at -4 - 0℃;
Stage #2: aniline With hydrogenchloride; sodium nitrite at -4 - 0℃;
Stage #3: In ethanol; water for 3h; cooling;
98%
Stage #1: aniline With hydrogenchloride; sodium nitrite In ethanol; water at -5℃;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at 20℃;
95%
Stage #1: aniline With hydrogenchloride; sodium nitrite In water at 0℃; for 1h;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at 0 - 20℃; for 4h;
76%
4-hydroxythiobenzamide
25984-63-8

4-hydroxythiobenzamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

(2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester)
161797-99-5

(2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester)

Conditions
ConditionsYield
In ethanol at 65 - 70℃; for 3h;98%
In spirit at 60 - 65℃; for 2.5h;90.7%
In isopropyl alcohol at 55 - 85℃; for 3h;58%
2,2-diphenylacetic acid
117-34-0

2,2-diphenylacetic acid

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl 2-(2,2-diphenylacetoxy)-3-oxobutanoate
1434871-32-5

ethyl 2-(2,2-diphenylacetoxy)-3-oxobutanoate

Conditions
ConditionsYield
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 17h;98%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 17h;98%
With N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 17h;98%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

2-oxo-propionic acid ethyl ester
617-35-6

2-oxo-propionic acid ethyl ester

Conditions
ConditionsYield
With aluminum (III) chloride; Oxone In water at 20℃; for 3h;98%
thionicotinamide
4621-66-3

thionicotinamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

2-pyridyl-4-methylthiazole-5-carboxylic acid ethyl ester

2-pyridyl-4-methylthiazole-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
In ethanol at 75℃; for 2h;97.5%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

2-(5-bromo-2-oxoindolin-3-ylidene)-N-p-tolylhydrazine carbothioamide
92461-01-3

2-(5-bromo-2-oxoindolin-3-ylidene)-N-p-tolylhydrazine carbothioamide

2-{[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazono}-4-methyl-3-p-tolyl-2,3-dihydro-thiazole-5-carboxylic acid

2-{[5-Bromo-2-oxo-1,2-dihydro-indol-(3Z)-ylidene]-hydrazono}-4-methyl-3-p-tolyl-2,3-dihydro-thiazole-5-carboxylic acid

Conditions
ConditionsYield
With sodium acetate In ethanol for 4h; Heating;97%
4-chloro-aniline
106-47-8

4-chloro-aniline

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl 2-chloro-2-(4-chlorophenylhydrazono)acetate
27143-09-5

ethyl 2-chloro-2-(4-chlorophenylhydrazono)acetate

Conditions
ConditionsYield
Stage #1: 4-chloro-aniline With hydrogenchloride; sodium nitrite In ethanol at -5 - 5℃;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at -5℃; for 4h; Further stages.;
97%
2-(2,4-dichlorophenyl)ethanethioamide
883946-62-1

2-(2,4-dichlorophenyl)ethanethioamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl 2-(2,4-dichlorobenzyl)-4-methyl-1,3-thiazole-5-carboxylate
1318757-73-1

ethyl 2-(2,4-dichlorobenzyl)-4-methyl-1,3-thiazole-5-carboxylate

Conditions
ConditionsYield
With pyridine at 20℃; for 48h;97%
In methanol Reflux;
C13H15NO5

C13H15NO5

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

(4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide
1412897-07-4

(4R,5R)-5-acetyl-3-((S)-2-ethoxy-1-hydroxy-2-oxoethyl)-5-(ethoxycarbonyl)-4-(p-tolyl)-4,5-dihydro isoxazole 2-oxide

Conditions
ConditionsYield
With quinindine In dichloromethane at -78℃; for 72h; Inert atmosphere; enantioselective reaction;97%
tert-butyl (E)-5-bromo-3-(2-ethoxy-2-oxoethylidene)-2-oxoindoline-1-carboxylate
1282523-26-5

tert-butyl (E)-5-bromo-3-(2-ethoxy-2-oxoethylidene)-2-oxoindoline-1-carboxylate

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

1'-tert-butyl 2,3-diethyl (1R,2R,3S)-3-acetyl-5'-bromo-2'-oxo-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-1',2,3-tricarboxylate
1441088-59-0

1'-tert-butyl 2,3-diethyl (1R,2R,3S)-3-acetyl-5'-bromo-2'-oxo-1',2'-dihydrospiro[cyclopropane-1,3'-indole]-1',2,3-tricarboxylate

Conditions
ConditionsYield
With 1-(2,6-diisopropylphenyl)-3-((1S)-((2S,4S,5R)-5-ethylquinuclidin-2-yl)(6-methoxyquinolin-4-yl)methyl)thiourea; sodium hydrogencarbonate In chloroform at 20℃; for 24h; Michael Addition; stereoselective reaction;97%
C17H18BrNO5

C17H18BrNO5

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

1'-(tert-butyl)-2,3-diethyl-(1S,2R,3S)-2-acetyl-5'-bromo-2'-oxospiro[cyclopropane-1,3'-indoline]-1',2,3-tricarboxylate
1476734-77-6

1'-(tert-butyl)-2,3-diethyl-(1S,2R,3S)-2-acetyl-5'-bromo-2'-oxospiro[cyclopropane-1,3'-indoline]-1',2,3-tricarboxylate

Conditions
ConditionsYield
With C33H44N4OS; sodium hydrogencarbonate In chloroform at 20℃; Michael Addition;97%
3-formyl-4-isobutoxythiobenzamide

3-formyl-4-isobutoxythiobenzamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

2-(3-formyl-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester
161798-03-4

2-(3-formyl-4-isobutyloxyphenyl)-4-methylthiazole-5-carboxylic acid ethyl ester

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 60℃; for 4h;97%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

4-Aminobenzonitrile
873-74-5

4-Aminobenzonitrile

ethyl 2-chloro-2-(2-(4-cyanophenyl)hydrazono)acetate

ethyl 2-chloro-2-(2-(4-cyanophenyl)hydrazono)acetate

Conditions
ConditionsYield
Stage #1: 4-Aminobenzonitrile With hydrogenchloride; sodium nitrite In water at 0 - 5℃; for 0.5h;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water at 0 - 5℃;
97%
ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

2-chloro-1,3-butanediol
89166-22-3

2-chloro-1,3-butanediol

Conditions
ConditionsYield
With sodium tetrahydroborate In methanol at 20℃; for 0.5h;96%
4-(2,2,2,-trifluoroethoxy)aniline
57946-61-9

4-(2,2,2,-trifluoroethoxy)aniline

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

C12H12ClF3N2O3
1245835-45-3

C12H12ClF3N2O3

Conditions
ConditionsYield
Stage #1: 4-(2,2,2,-trifluoroethoxy)aniline With trifluoroacetic acid; isopentyl nitrite In acetonitrile at 0℃;
Stage #2: ethyl 2-chloro-3-oxo-butyrate With sodium acetate In ethanol; water Japp-Klingemann reaction;
96%
2-(3-fluoro-5-(trifluoromethyl)phenyl)ethanethioamide
1318757-95-7

2-(3-fluoro-5-(trifluoromethyl)phenyl)ethanethioamide

ethyl 2-chloro-3-oxo-butyrate
609-15-4

ethyl 2-chloro-3-oxo-butyrate

ethyl 2-[3-fluoro-5-(trifluoromethyl)benzyl]-4-methyl-1,3-thiazole-5-carboxylate
1318757-96-8

ethyl 2-[3-fluoro-5-(trifluoromethyl)benzyl]-4-methyl-1,3-thiazole-5-carboxylate

Conditions
ConditionsYield
With pyridine In ethanol at 20℃; for 48h;96%
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