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Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $15.0 / 55.0
Type:Trading Company
inquiryPerindopril erbumine CAS 107133-36-8 Company profile Wuhan Fortuna Chemical Co.,Ltd established in 2006, is a big integrative chemical enterprise being engaged in Pharmaceutical & its intermediates, Food/Feed additives, Fine chemicals in dis
Cas:107133-36-8
Min.Order:10 Kilogram
FOB Price: $10.0
Type:Trading Company
inquiryPerindopril Erbumine CAS:107133-36-8 white or off-white crystalline powder HANGZHOU THINK CHEMICAL CO., LTD. (THINKCHEM) is an integrative corporation of trade, research and contract manufacture. With about ten years of busines
Cas:107133-36-8
Min.Order:1 Kilogram
Negotiable
Type:Other
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:107133-36-8
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:107133-36-8
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryAdvantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:107133-36-8
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryName: Perindopril erbumine Synonyms: 1-[2-(1-Ethoxycarbonylbutylamino)propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid 2-methyl-2-propanamine (1:1) CAS:107133-36-8 MF: C19H32N2O5·C4H11N Appearance:White powder Storage:Sto
Appearance:White or almost white crystalline powder Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Any port of china
Cas:107133-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:107133-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:107133-36-8
Min.Order:25 Kilogram
FOB Price: $2264.0 / 2384.0
Type:Trading Company
inquiryPerindopril erbumine CAS:107133-36-8 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic int
Cas:107133-36-8
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:107133-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
We are concentrating on APIs and pharmaceutical intermediates. With in depth knowledge and understanding in this industry, we are indulged in supplying a wide assortments of Cefquinome sulfate from Wuhan, Hubei, China. It is made obtainable from us
Cas:107133-36-8
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryHebei Mojin Biotechnology Co., Ltd,Our business covers more than 30 countries, most of the big customers come from Europe, America and other countries in the world, we can guarantee the quality and price. In recent decades, with the efforts of all em
Cas:107133-36-8
Min.Order:1 Gram
FOB Price: $5000.0
Type:Trading Company
inquiryOur Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Cas:107133-36-8
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures
Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $460.0 / 500.0
Type:Lab/Research institutions
inquiryHubei Yuanmeng Biological Technology Co., Ltd., which is located in Wuhan, China. We are specializing in the exportation of APIs, and plant extracts ect. Our products has been exported to America, Australia, Brazil, the Europe, Middle East and other
Cas:107133-36-8
Min.Order:1 Kilogram
FOB Price: $3.0 / 5.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
A substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:107133-36-8
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:107133-36-8
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiry107133-36-8 Perindopril erbumineAppearance:White powder Storage:Store in cool & dry place Package:according to customers' requirements Application:Medicine Transportation:By air(EMS or EUB or FedEx or TNT ect...) or by sea(FOB or CIF or CNF ect...)or
We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov
Cas:107133-36-8
Min.Order:100 Gram
FOB Price: $100.0 / 2000.0
Type:Lab/Research institutions
inquirySuperior quality, moderate price & quick delivery. Appearance:White solid Storage:Stored in cool, dry and ventilation place; Away from fire and heat Package: 1g/bag, 5g/bag, 10g/bag, 100g/bag, 1kg/bag or as per your request Application:An angio
Conditions | Yield |
---|---|
In ethyl acetate Heating / reflux; | 95% |
In ethyl acetate Heating / reflux; | 95% |
In ethyl acetate Heating / reflux; | 95% |
Perindopril
perindopril tert-butylamine
Conditions | Yield |
---|---|
With tert-butylamine In ethyl acetate; acetonitrile Heating / reflux; | 95% |
With tert-butylamine In ethyl acetate at 20℃; for 1 - 1.5h; | 65% |
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
Stage #1: (2S,3aS,7aS)-perhydroindole-2-carboxylic acid With tert-butylimino-tri(pyrrolidino)phosphorane In acetonitrile Stage #2: N-[1(S)-(ethoxycarbonyl)butyl]-L-alanine ester of acetonoxime In acetonitrile at 50℃; for 0.5h; Stage #3: tert-butylamine In dichloromethane at 0 - 10℃; for 0.5h; Product distribution / selectivity; | 90% |
Stage #1: (2S,3aS,7aS)-perhydroindole-2-carboxylic acid With 1,8-diazabicyclo[5.4.0]undec-7-ene In acetonitrile Stage #2: N-[1(S)-(ethoxycarbonyl)butyl]-L-alanine ester of acetonoxime In acetonitrile at 40 - 45℃; Stage #3: tert-butylamine With hydrogenchloride In acetonitrile at 50 - 60℃; Product distribution / selectivity; | 90% |
Stage #1: benzylperindopril oxalate With hydrogen; 5%-palladium/activated carbon In ethanol at 30℃; under 3677.86 Torr; for 3h; Stage #2: tert-butylamine In ethanol Product distribution / selectivity; |
(2S,3aS,7aS)-perhydroindole-2-carboxylic acid
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
Stage #1: (2S,3aS,7aS)-perhydroindole-2-carboxylic acid With chloro-trimethyl-silane; triethylamine In dichloromethane at 20 - 25℃; for 2h; Stage #2: N-((S)-1-carbethoxybutyl)-L-alanyl chloride hydrochloride With triethylamine In dichloromethane at -15℃; for 2h; Stage #3: tert-butylamine In Isopropyl acetate Product distribution / selectivity; | 86% |
Stage #1: (2S,3aS,7aS)-perhydroindole-2-carboxylic acid With chloro-trimethyl-silane; triethylamine In dichloromethane at 20 - 25℃; for 2h; Stage #2: N-((S)-1-carbethoxybutyl)-L-alanyl chloride hydrochloride With triethylamine In dichloromethane at -15℃; for 2h; Stage #3: tert-butylamine In ethyl acetate Product distribution / selectivity; | 80% |
Stage #1: (2S,3aS,7aS)-perhydroindole-2-carboxylic acid With chloro-trimethyl-silane; triethylamine In dichloromethane at 20 - 25℃; for 2h; Stage #2: N-((S)-1-carbethoxybutyl)-L-alanyl chloride hydrochloride With triethylamine In dichloromethane at -15℃; for 2h; Stage #3: tert-butylamine In DMF (N,N-dimethyl-formamide) Product distribution / selectivity; | 78% |
Conditions | Yield |
---|---|
With hydrogenchloride; tert-butylamine; triethylamine In dichloromethane; water; acetonitrile | A 81% B n/a |
C12H23NO2Si
N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
Stage #1: N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine With 1H-imidazole; thionyl chloride In dichloromethane at -10℃; for 2h; Stage #2: C12H23NO2Si In dichloromethane at -10 - 25℃; for 21h; Stage #3: tert-butylamine In acetonitrile Heating / reflux; | 61% |
Conditions | Yield |
---|---|
With hydrogen; palladium on activated charcoal In ethyl acetate under 2068.65 Torr; for 8h; |
Conditions | Yield |
---|---|
In dichloromethane Product distribution / selectivity; | |
In water Product distribution / selectivity; |
Conditions | Yield |
---|---|
In water at 20℃; for 1h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
With hydrogen; 5%-palladium/activated carbon In ethanol at 30℃; under 3677.86 Torr; for 3h; Product distribution / selectivity; |
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
In water Product distribution / selectivity; |
Conditions | Yield |
---|---|
In 2,2-dimethoxy-propane at 25 - 30℃; for 4 - 5h; Product distribution / selectivity; | |
at 25 - 30℃; for 4 - 5h; Product distribution / selectivity; |
Conditions | Yield |
---|---|
Stage #1: (2S,3aS,7aS)-1-{2-[1-(ethoxycarbonyl)-(S)-butylamine]-(S)-propionyl}octahydroindole-2-carboxylic acid 4-methoxybenzyl ester With hydrogen; palladium on activated charcoal In ethyl acetate under 2068.65 Torr; for 5h; Stage #2: tert-butylamine In ethyl acetate at 45℃; for 2h; |
(2S,3aS,7aS)-octahydroindole-2-carboxylic acid trimethylsilyl ester
N-[1(S)-ethoxycarbonyl-1-butyl]-(S)-alanyl chloride hydrochloride
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
Stage #1: N-[1(S)-ethoxycarbonyl-1-butyl]-(S)-alanyl chloride hydrochloride With 1H-imidazole In dichloromethane at 10 - 15℃; for 1h; Stage #2: (2S,3aS,7aS)-octahydroindole-2-carboxylic acid trimethylsilyl ester In dichloromethane at 10℃; for 3h; Stage #3: tert-butylamine In dichloromethane at 10 - 40℃; for 1h; Product distribution / selectivity; |
N-[1(S)-ethoxycarbonyl-1-butyl]-(S)-alanyl chloride hydrochloride
(2S,3aS,7aS)-perhydroindole-2-carboxylic acid
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
Stage #1: N-[1(S)-ethoxycarbonyl-1-butyl]-(S)-alanyl chloride hydrochloride With 1H-imidazole In dichloromethane at -5 - 0℃; for 1h; Stage #2: (2S,3aS,7aS)-perhydroindole-2-carboxylic acid In dichloromethane at -5 - 25℃; for 4.75h; Stage #3: tert-butylamine In dichloromethane at 10 - 40℃; for 1h; Product distribution / selectivity; |
(2S,3aS,7aS)-phenylmethyl octahydroindole-2-carboxylate hydrochloride
N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine
tert-butylamine
perindopril tert-butylamine
Conditions | Yield |
---|---|
Stage #1: (2S,3aS,7aS)-phenylmethyl octahydroindole-2-carboxylate hydrochloride; N-<1(S)-(ethoxycarbonyl)butyl>-L-alanine With triethylamine In Isopropyl acetate at 10 - 15℃; for 0.25h; Stage #2: With 2,4,6-tripropyl-1,3,5,2,4,6-trioxatriphosphinane-2,4,6-trioxide In Isopropyl acetate at -10 - 30℃; for 6h; Stage #3: tert-butylamine With hydrogen; 5% palladium over charcoal In ethanol |
(S)-indoline-2-carboxylic acid
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: hydrogen; 8 % Pd/C / methanol / 55 - 65 °C / 37503.8 Torr / Autoclave 2.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 2.2: 4 h / -5 - 5 °C 3.1: ethyl acetate / 0.5 h View Scheme |
2-chloro-benzaldehyde
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 8 steps 1.1: sodium acetate; acetic anhydride / 0.5 h / 20 °C / Inert atmosphere 1.2: 90 - 100 °C 2.1: sodium / 40 - 50 °C / Inert atmosphere 3.1: hydrogen; [Rhcod(S)-DuanPhos]BF4 / ethanol / 45 - 55 °C / 15001.5 Torr / Autoclave 4.1: potassium carbonate; copper(l) chloride / dimethyl sulfoxide / 100 - 105 °C / Inert atmosphere 5.1: sulfuric acid; water / Reflux 6.1: hydrogen; 8 % Pd/C / methanol / 55 - 65 °C / 37503.8 Torr / Autoclave 7.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 7.2: 4 h / -5 - 5 °C 8.1: ethyl acetate / 0.5 h View Scheme |
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 7 steps 1.1: sodium / 40 - 50 °C / Inert atmosphere 2.1: hydrogen; [Rhcod(S)-DuanPhos]BF4 / ethanol / 45 - 55 °C / 15001.5 Torr / Autoclave 3.1: potassium carbonate; copper(l) chloride / dimethyl sulfoxide / 100 - 105 °C / Inert atmosphere 4.1: sulfuric acid; water / Reflux 5.1: hydrogen; 8 % Pd/C / methanol / 55 - 65 °C / 37503.8 Torr / Autoclave 6.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 6.2: 4 h / -5 - 5 °C 7.1: ethyl acetate / 0.5 h View Scheme |
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 6 steps 1.1: hydrogen; [Rhcod(S)-DuanPhos]BF4 / ethanol / 45 - 55 °C / 15001.5 Torr / Autoclave 2.1: potassium carbonate; copper(l) chloride / dimethyl sulfoxide / 100 - 105 °C / Inert atmosphere 3.1: sulfuric acid; water / Reflux 4.1: hydrogen; 8 % Pd/C / methanol / 55 - 65 °C / 37503.8 Torr / Autoclave 5.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 5.2: 4 h / -5 - 5 °C 6.1: ethyl acetate / 0.5 h View Scheme |
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 5 steps 1.1: potassium carbonate; copper(l) chloride / dimethyl sulfoxide / 100 - 105 °C / Inert atmosphere 2.1: sulfuric acid; water / Reflux 3.1: hydrogen; 8 % Pd/C / methanol / 55 - 65 °C / 37503.8 Torr / Autoclave 4.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 4.2: 4 h / -5 - 5 °C 5.1: ethyl acetate / 0.5 h View Scheme |
(S)-N-acetyl-2,3-dihydroindoline-2-carboxylic acid methyl ester
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 4 steps 1.1: sulfuric acid; water / Reflux 2.1: hydrogen; 8 % Pd/C / methanol / 55 - 65 °C / 37503.8 Torr / Autoclave 3.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 3.2: 4 h / -5 - 5 °C 4.1: ethyl acetate / 0.5 h View Scheme |
(2S,3aS,7aS)-perhydroindole-2-carboxylic acid
perindopril tert-butylamine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1.1: triethylamine; chloro-trimethyl-silane / dichloromethane / 2 h / 20 °C / Inert atmosphere 1.2: 4 h / -5 - 5 °C 2.1: ethyl acetate / 0.5 h View Scheme |
perindopril tert-butylamine
Conditions | Yield |
---|---|
With water In acetone at -80℃; | 100% |
perindopril tert-butylamine
Conditions | Yield |
---|---|
With water at 30 - 40℃; for 240h; Product distribution / selectivity; | 100% |
With water In acetonitrile at -50 - -45℃; Product distribution / selectivity; |
Conditions | Yield |
---|---|
With methanesulfonic acid In dimethyl sulfoxide at 70℃; for 1h; | 88% |
perindopril tert-butylamine
Perindopril
Conditions | Yield |
---|---|
With hydrogenchloride In dichloromethane; water at 10 - 30℃; for 0.5h; Product distribution / selectivity; | 80% |
With hydrogenchloride In dichloromethane; water pH=5.4; Product distribution / selectivity; | |
Stage #1: perindopril tert-butylamine With sulfuric acid In ethanol at 20 - 25℃; for 1.5h; Stage #2: With sodium hydroxide In dichloromethane; water pH=4.2; Product distribution / selectivity; | |
With calcium chloride In ethyl acetate Product distribution / selectivity; Heating / reflux; |
perindopril tert-butylamine
perindoprilat
Conditions | Yield |
---|---|
With sodium hydroxide for 72h; Ambient temperature; | 75% |
With water; 6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide at 59.84℃; for 120h; Kinetics; |
perindopril tert-butylamine
A
ethyl (2S)-2-[(3S,5aS,9aS,10aS)-3-methyl-1,4-dioxo-5a,6,7,8,9,9a,10,10a-octahydro-3H-pyrazino[1,2-a]indol-2-yl]pentanoate
B
perindoprilat
Conditions | Yield |
---|---|
With water at 40℃; Conversion of starting material; | A 0.04% B 0.03% |
perindopril tert-butylamine
dimethyl sulfoxide
1-chloro-2,4-dinitro-benzene
Conditions | Yield |
---|---|
at 30℃; Activation energy; Further Variations:; Temperatures; |
perindopril tert-butylamine
Conditions | Yield |
---|---|
With water at -15℃; for 1h; Product distribution / selectivity; |
octanol
perindopril tert-butylamine
Conditions | Yield |
---|---|
In ethyl acetate at 30 - 60℃; |
n-heptan1ol
perindopril tert-butylamine
Conditions | Yield |
---|---|
In toluene at 20 - 55℃; |
perindopril tert-butylamine
cyclohexanol
Conditions | Yield |
---|---|
In toluene at 20 - 65℃; | |
at 20 - 60℃; Product distribution / selectivity; |
pentan-1-ol
perindopril tert-butylamine
Conditions | Yield |
---|---|
In ethyl acetate at 20 - 60℃; |
Conditions | Yield |
---|---|
In ethyl acetate Heating / reflux; |
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