Item Specifications Results Appearance White crystalline powder White crystalline powder Assay ,%
Cas:61-90-5
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inquiryZorui combines R&D, production and sales into its operations, While continuously providing high-quality raw materials, we also provide and optimize technical solutions for customers to achieve mutual benefit. We adhere to the "quality, integ
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inquiryQuick Details Place of Origin: Shaanxi, China Type: Anti-Allergic Agents, Immune Function Agents, Vitamins, Amino Acids and Coenzymes CAS No.: 61-90
L-LeucineAppearance:White powder Package:Cartons,25kgs per carton
Assay data Assay 98.5% ~101.5% USP27 99.5% Quality data Identification Standardization
Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryProduct Name: L-Leucine Synonyms: (s)-2-amino-4-methylvalericacid;1-Leucine;2-Amino-4-methylpentanoic acid;2-amino-4-methylpentanoicacid;2-amino-4-me… Founded in 2014, as a professional international pharmaceutical corporation, headquarter
Product description: Product name L-Leucine CAS number 61-90-5 Assay ≥98% Appearance White crystalline powder Capacity 200mt/year Application Pharmaceutical raw materials and
hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
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inquiryUnique advantages of L-Leucine Cas 61-90-5 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White crystal or crystalline powder Storage:cool dry place Package:25kg/drum Appl
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inquiryCome From Nature / Building Healthy Life Beauty In Your Face / Nourishment Your Taste Bud. Professional Factory: We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of conten
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inquiry1.strict Quality control: Strictly in accordance with Chinese GMP(2010 version), guidelines issued by FDA,EDQM, and ICH relevant regulations, we have established a sound quality assurance system, implementing regular supervision and management in
L-Leucine[CAS:61-90-5] Name L-Leucine Synonyms L-2-Amino-4-methylpentanoic acid; (S)-2-Amino-4-methylpentanoic acid; L-Leu HANGZHOU THINK CHEMICAL CO., LTD. (THINKCH
The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiry20-year experience in Phytochemicals Each product has passed very strict tests (NMR\MS\HPLC) Agents in 13 countries Certified by ISO 9001:2008 quality management system Leader Supplier of Botanical Reference Materials in China
ADVANTAGE: 1. More than 3,000 Chinese medicine reference substances / standard products available from stock, issued on the same day, multiple cities can be delivered the next day 2. The products are provided with COA, HPLC, NMR, quality assurance,
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L-Leucine CAS 61-90-5 L-Leu CAS no 61-90-5 L-2-Amino-4-methylpentanoic acid (S)-2-Amino-4-methylpentanoic acid L-Leucine Manufacturer High quality Best price In stock factory CAS 61-90-5 L-Leucine COA TDS price MSDS highly quality and immed
Cas:61-90-5
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inquiryName:L-Leucine CAS NO:61-90-5 Grade:Medical chemical industry, scientific research and export Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Security without vulnerability
Cas:61-90-5
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inquiryL-Leucine Basic information One of the eight essential amino acids Identification Test Content Analysis toxicity Application limitation The maximum amount permitted of food additives maximum allowable resid
Cas:61-90-5
Min.Order:1 Gram
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inquiryWith our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod
Product name L-Leucine Cas number 61-90-5 Appearance White powder Purity (%) 99% Appearance: white powder Storage:Store in cool and
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO
Cas:61-90-5
Min.Order:1 Gram
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inquiryNutrional Supplyment Amino Acid USP Aji CAS 61-90-5 99% L-Leucine Powder Pharmaceutical Raw Material MOQ: 1kg Form: Powder Colour: White Test: HPLC Function: amino acid Grade:
Cas:61-90-5
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inquiryPoc-Leu-OH
L-leucine
Conditions | Yield |
---|---|
With resin bound tetrathiomolybdate In methanol at 28℃; for 1.5h; ultrasonic bath; | 100% |
N-tert-butoxycarbonyl-L-leucine
L-leucine
Conditions | Yield |
---|---|
With water at 170℃; for 0.05h; Microwave irradiation; | 100% |
With tetradecyl(trihexyl)phosphonium bistriflamide; trifluoroacetic acid at 130℃; for 0.166667h; Ionic liquid; | 98% |
Multi-step reaction with 3 steps 1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 2: trifluoroacetic acid 3: E. coli BL21 Star (DE3) S30 extract / aq. buffer / 6 h / 37 °C / pH 7.5 View Scheme | |
Multi-step reaction with 3 steps 1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate 2: trifluoroacetic acid 3: E. coli BL21 Star (DE3) S30 extract / aq. buffer / 6 h / 37 °C / pH 7.5 View Scheme | |
With trifluoroacetic acid In dichloromethane at 0 - 20℃; for 2h; |
L-leucine
Conditions | Yield |
---|---|
With pronase In water at 37℃; for 46h; Time; Enzymatic reaction; | 100% |
Conditions | Yield |
---|---|
With 3,5-dinitrosalicylaldehyde; Alcalase In water; acetonitrile at 35℃; for 3h; pH=7.5; Enzymatic reaction; optical yield given as %ee; | 99% |
L-leucine
Conditions | Yield |
---|---|
With hydrogen; trifluoroacetic acid; palladium dihydroxide In methanol; water under 3750.3 Torr; for 24h; | 98% |
hexan-1-amine
(S)-2-(3,5-Dinitro-4-oxo-4H-pyridin-1-yl)-4-methyl-pentanoic acid
A
L-leucine
B
1-hexyl-3,5-dinitro-4-pyridone
Conditions | Yield |
---|---|
In pyridine Product distribution; | A 97% B n/a |
(2S,5S)-N-<(S)-N-bis(methylthio)methyleneleucyl>-2,5-bis(methoxymethoxymethyl)pyrrolidine
L-leucine
Conditions | Yield |
---|---|
With hydrogenchloride for 4h; Heating; | 96% |
Conditions | Yield |
---|---|
In water at 37℃; for 2h; NADH, ammonium chloride, sodium formate, D-amino acid oxidase, catalase, leucine dehydrogenase, formate dehydrogenase, Tris-HCl buffer, pH 8.5; | 95% |
With porcine kidney D-amino acid oxidase (EC 1.4.3.3.); sodium cyanoborohydride; flavin adenine dinucleotide In phosphate buffer at 37℃; | 90% |
With D-amino acid oxidase; E. coli branched-chain amino acid aminotransferase In water at 37℃; for 72h; Tris buffer, pH 8.5, 1mM EDTA, monosodium glutamate, bovine serum albumin, catalase, pyridoxal 5'-phosphate; | 87% |
(S)-2-[{(allyloxy)carbonyl}amino]-4-methylpentanoic acid
L-leucine
Conditions | Yield |
---|---|
With tri-n-butyl-tin hydride; bis-triphenylphosphine-palladium(II) chloride In dichloromethane Ambient temperature; | 95% |
N-carbamoyl-L-leucine
L-leucine
Conditions | Yield |
---|---|
With NH4Cl-NH4OH buffer pH 8.5; nickel dichloride at 60℃; for 24h; N-carbamyl-L-amino acid aminohydrolase; | 94% |
With Tris-HCl buffer; N-carbamoyl-L-amino acid hydrolase; iron(II) sulfate at 30℃; for 2h; | |
With potassium phosphate buffer; Pseudomonas sp. AJ-11220 In various solvent(s) at 30℃; for 1h; |
Diphenyl-N-(benzyloxycarbonyl)-L-leucyl-(2-decarboxy-L-alanin-2-yl)phosphonat
A
L-leucine
B
(R)-(1-aminoethyl)phosphonic acid
Conditions | Yield |
---|---|
With hydrogenchloride for 24h; Heating; | A 10% B 88% |
L-valine
L-Leucin-N-carbonsaeureanhydrid
A
L-leucine
B
L-leucyl-glycine
C
N-carbamoylglycine
Conditions | Yield |
---|---|
With water; potassium hydroxide; potassium borate buffer at 3℃; Product distribution; effect of use of various amino acid and NCA with various concentrations; effect of use various temp.; extent of hydrolysis; | A n/a B 87.1% C n/a D n/a |
C72H135NO7
L-leucine
Conditions | Yield |
---|---|
With trifluoroacetic acid In dichloromethane at 20℃; | 86% |
(SS,S)-2-(p-toluenesulfinylamino)-4-methylpentanenitrile
L-leucine
Conditions | Yield |
---|---|
With hydrogenchloride In water for 6h; Heating; | 85% |
phenylmethyl (4S)-4-(2-methylpropyl)-5-oxo-1,3-oxazolidine-3-carboxylate
L-leucine
Conditions | Yield |
---|---|
With boron trichloride In dichloromethane at 25℃; for 0.333333h; | 84% |
4-methyloxovaleric acid anion
L-leucine
Conditions | Yield |
---|---|
With ammonium formate; tris hydrochloride; nicotinamide adenine dinucleotide; formate dehydrogenase; phenylalanine dehydrogenase In water at 30℃; for 24h; | 83% |
With L-glutamic acid; pyridoxal 5'-phosphate In water at 40℃; for 18h; E.coli Aspartate transaminase, pH 8; | 40% |
((S)-1-Cyano-3-methyl-butyl)-carbamic acid methyl ester
L-leucine
Conditions | Yield |
---|---|
With hydrogenchloride In water for 7h; Heating; | 81% |
Conditions | Yield |
---|---|
With sodium hydrogen telluride In N,N-dimethyl-formamide at 70℃; for 3.5h; | 80% |
Conditions | Yield |
---|---|
With boron trichloride In dichloromethane at 25℃; for 0.333333h; | 77% |
With hydrogen; palladium on activated charcoal In ethanol at 20℃; for 1h; | 22 mg |
With cell extract of Sphingomonas paucimobilis SC 16113 In water at 42℃; for 20h; Enzymatic reaction; | 100 % Chromat. |
With ethylenediaminetetraacetic acid; phenylmethylsulphonyl fluoride; water In aq. phosphate buffer at 30℃; Kinetics; Reagent/catalyst; Microbiological reaction; Enzymatic reaction; | |
Multi-step reaction with 3 steps 1.1: triethylamine; isobutyl chloroformate / tetrahydrofuran / 0.5 h / Cooling with ice 1.2: 15 h / 10 - 35 °C 2.1: 2% active carbon-supported palladium; hydrogen / methanol / 1 h / 10 - 35 °C / 760.05 Torr 3.1: pronase / water / 46 h / 37 °C / Enzymatic reaction View Scheme |
D,L-leucine benzyl ester hydrochloride
L-leucine
Conditions | Yield |
---|---|
Stage #1: D,L-leucine benzyl ester hydrochloride With lithium carbonate In water; tert-butyl alcohol at 23℃; for 0.166667h; Resolution of racemate; Stage #2: With 2-Hydroxymethylpyridine; Alcalase; water; zinc(II) acetate dihydrate In tert-butyl alcohol at 23℃; for 4h; Resolution of racemate; Enzymatic reaction; optical yield given as %ee; | 77% |
A
L-leucine
B
(S)-1-aminoethylphosphonic acid
Conditions | Yield |
---|---|
With hydrogenchloride for 16h; Heating; | A 28% B 70% |
Conditions | Yield |
---|---|
With zinc(II) perchlorate; (R)-15-amino-methyl-14-hydroxy-5,5-dimethyl-2,8-dithia<9>(2,5)pyridinophane In methanol for 24h; Ambient temperature; | 68% |
With leucine dehydrogenase Yield given; |
5-isobutyl-imidazolidine-2,4-dione
L-leucine
Conditions | Yield |
---|---|
With sodium hydroxide; air at 30℃; for 72h; Pseudomonas sp. Strain NS671; | 68% |
(2S)-(+)-2-<(1S,2S)-(2-Hydroxy-1-hydroxymethyl-2-phenylethyl)amino>-4-methylvaleriansaeure
L-leucine
Conditions | Yield |
---|---|
With ammonium hydroxide; periodic acid In water for 14h; Ambient temperature; | 67% |
L-leucine
Conditions | Yield |
---|---|
With ruthenium nanoparticles dispersed in a polyvinylpyrrolidone matrix; amberlyst A-21 In methanol; dichloromethane | 65% |
DL-leucine methyl ester
p-methoxybenzyloxycarbonyl-Phe-OMe
A
L-leucine
B
Moz-Phe-D-Leu-OMe
Conditions | Yield |
---|---|
Stage #1: DL-leucine methyl ester With Alcalase; water In tert-butyl alcohol at 25℃; pH=8.5; kinetic resolution; Stage #2: p-methoxybenzyloxycarbonyl-Phe-OMe With Alcalase In tert-butyl alcohol Condensation; | A n/a B 59% |
L-leucine
Conditions | Yield |
---|---|
With hydrogenchloride at 110℃; for 12h; | 52% |
(2S)-(N-para-toluenesulphonylamino)-4-methylpentanoic acid tert-butyl ester
L-leucine
Conditions | Yield |
---|---|
With hydrogen bromide; acetic acid; phenol for 24h; Ambient temperature; | 49% |
With hydrogen bromide; acetic acid 1.) phenol, 25 deg C, 24 h; |
Conditions | Yield |
---|---|
With sodium hydroxide; acylase Amano 30000 from Aspergillus spp. (30 u/mg); water; cobalt(II) chloride at 37 - 40℃; for 48h; | 39% |
Herstellung mit Hilfe eines Enzym-Praeparats aus Aspergillus und Penicillium; |
Conditions | Yield |
---|---|
With thionyl chloride | 100% |
With thionyl chloride | 100% |
With thionyl chloride at 0 - 20℃; | 94% |
Conditions | Yield |
---|---|
With thionyl chloride | 100% |
With amberlyst-15 Ambient temperature; | 77% |
With thionyl chloride for 10h; Heating; | 70% |
Conditions | Yield |
---|---|
With sodium hydroxide In water at 0 - 20℃; | 100% |
With sodium hydroxide at 0℃; for 1h; | 99% |
With sodium hydroxide In water at 20℃; for 2h; | 92% |
L-leucine
methyl chloroformate
(S)-2-(methoxycarbonylamino)-4-methylpentanoic acid
Conditions | Yield |
---|---|
Stage #1: L-leucine; methyl chloroformate With sodium hydroxide In 1,4-dioxane; water at 0 - 60℃; for 18h; pH=8 - 9; Stage #2: With hydrogenchloride In water | 100% |
Stage #1: L-leucine; methyl chloroformate With sodium hydroxide In water at 0 - 20℃; Stage #2: With hydrogenchloride In water | 84% |
With alkali In water | 75% |
Conditions | Yield |
---|---|
With methyloxirane In tetrahydrofuran at 25℃; for 0.25h; | 100% |
With methyloxirane In tetrahydrofuran for 2h; Ambient temperature; | 94% |
With sodium hydroxide | |
In tetrahydrofuran Ambient temperature; 7 - 10 days; Yield given; |
Conditions | Yield |
---|---|
With sodium cyanoborohydride; acetic acid In water; acetonitrile at 22℃; for 1h; pH=Ca.7; Inert atmosphere; | 100% |
With sodium dihydrogenphosphate; zinc at 30℃; for 20h; | 95% |
With sodium tetrahydroborate In 2,2,2-trifluoroethanol for 48h; Reflux; | 88% |
Conditions | Yield |
---|---|
With sodium hydroxide In 1,4-dioxane at 25℃; for 23h; | 100% |
With sodium hydroxide In 1,4-dioxane; water at 0℃; | 100% |
With sodium hydroxide In tetrahydrofuran; water at 20℃; for 19h; | 99% |
Conditions | Yield |
---|---|
Stage #1: methanol With thionyl chloride for 1h; Cooling with ice; Stage #2: L-leucine at 20 - 66℃; for 6.5h; | 100% |
With thionyl chloride at 20℃; for 4h; | 99% |
With thionyl chloride | 99% |
Conditions | Yield |
---|---|
With sodium carbonate In water at 20℃; for 2h; | 100% |
With sodium carbonate In water at 20℃; for 2h; | 100% |
With sodium hydrogencarbonate In water for 1h; Ambient temperature; | 66% |
With sodium carbonate In water | 35% |
With sodium carbonate In water at 20℃; for 5h; |
L-leucine
toluene-4-sulfonic acid
benzyl alcohol
L-leucine benzyl ester p-toluenesulfonate
Conditions | Yield |
---|---|
In cyclohexane; water for 4h; Dean-Stark; Reflux; | 100% |
In toluene for 20h; Reflux; | 85% |
In toluene for 4h; Reflux; Inert atmosphere; | 82% |
Conditions | Yield |
---|---|
With 1H-imidazole at 100℃; for 1h; Inert atmosphere; | 100% |
With 1H-imidazole at 120℃; for 0.5h; | 97% |
With 1H-imidazole at 120℃; | 95.4% |
L-leucine
bis-1,4-(hydroxymethyl)cyclohexane
L,L-leucine 1,4-cyclohexanedimethanol diester
Conditions | Yield |
---|---|
Stage #1: L-leucine; bis-1,4-(hydroxymethyl)cyclohexane With toluene-4-sulfonic acid In toluene at 150℃; for 30h; Heating / reflux; Stage #2: With sodium hydrogencarbonate In water; toluene at 60℃; | 100% |
L-leucine
bis-1,4-(hydroxymethyl)cyclohexane
L,L-leucine 1,4-cyclohexanedimethanol diester
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid In toluene at 20 - 150℃; for 30h; Heating / reflux; | 100% |
1-[(1-benzothien-2-ylcarbonyl)oxy]-2,5-pyrrolidinedione
L-leucine
(benzo[b]thiophene-2-carbonyl)-l-leucine
Conditions | Yield |
---|---|
With triethylamine In ethanol; dichloromethane; water at 20℃; | 100% |
Stage #1: 1-[(1-benzothien-2-ylcarbonyl)oxy]-2,5-pyrrolidinedione; L-leucine With triethylamine In ethanol; dichloromethane; water at 20℃; Stage #2: With hydrogenchloride In dichloromethane; water | 100% |
Stage #1: 1-[(1-benzothien-2-ylcarbonyl)oxy]-2,5-pyrrolidinedione; L-leucine With triethylamine In ethanol; dichloromethane; water at 5 - 20℃; for 18.1667h; Stage #2: With hydrogenchloride In ethanol; dichloromethane; water | |
With triethylamine In ethanol; dichloromethane; water at 5 - 20℃; | |
With triethylamine In ethanol; dichloromethane; water at 5 - 20℃; |
L-leucine
L-phenylalanine
L-tyrosine
glycine
H-Tyr-Gly-Gly-Phe-Leu-NH2
Conditions | Yield |
---|---|
Stage #1: L-tyrosine With BF4(1-)*C7H13N3Pol(1+); benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In 1-methyl-pyrrolidin-2-one at 25℃; for 1h; Ionic liquid; Automated synthesizer; solid phase reaction; Stage #2: glycine In 1-methyl-pyrrolidin-2-one at 25℃; for 1h; Ionic liquid; Automated synthesizer; solid phase reaction; Stage #3: L-leucine; L-phenylalanine Further stages; | 100% |
Conditions | Yield |
---|---|
With lithium hydride In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With sodium methylate In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With caesium carbonate In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With calcium hydride In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With lithium hydride In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With sodium methylate In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With caesium carbonate In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With calcium hydride In methanol Reflux; | 100% |
Conditions | Yield |
---|---|
With potassium carbonate In water for 2h; Reflux; | 100% |
Conditions | Yield |
---|---|
With caesium carbonate at 90℃; for 12h; | 100% |
L-leucine
1-((2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyridin-1-ium-3-carboxylate
Conditions | Yield |
---|---|
In water pH=5.61; Cooling with ice; | 100% |
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