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SJZ THLD IMP & EXP CO LTD

we are committed to excellence.From manufacturing to packaging and delivery, we provide quality, reliability and the highest degree of customer service.Our scope of service is organized/structured around the unique needs of each client.Our mission is

High quality aciclovir cas 59277-89-3 best price

Cas:59277-89-3

Min.Order:50 Kilogram

FOB Price: $52.0 / 55.0

Type:Trading Company

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Siwei Development Group Ltd.

Product name: Acyclovir CAS No.:59277-89-3 Molecule Formula:C8H11N5O3 Molecule Weight: 225.2 Purity: 99.5% Package: 25kg/drum Description:White crystals or crystalline powder Manufacture Standards:USP/EP TESTING IT

Pharma Grade Acyclovir

Cas:59277-89-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Hangzhou Dingyan Chem Co., Ltd

Items Standard Result Character A white crystalline powde Conform IR The infrared absorption spec

High purity Various Specifications acycloguanosine CAS:59277-89-3

Cas:59277-89-3

Min.Order:1 Gram

FOB Price: $100.0 / 500.0

Type:Manufacturers

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality Acyclovir supplier in China

Cas:59277-89-3

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

Jinlan Pharm-Drugs Technology Co.,Limited (with its export company Hangzhou Royall Import & Export Co.,Ltd.)is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pu

Acyclovir CAS No.59277-89-3

Cas:59277-89-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Hebei yanxi chemical co.,LTD.

hebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm

Acyclovir factory/seller/manufacturer in China

Cas:59277-89-3

Min.Order:1 Metric Ton

FOB Price: $1.0 / 3.0

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages for Acyclovir Cas 59277-89-3 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to pale yellow , crystalline powder odourless or almost odourless Storage

Factory supply Acyclovir Cas 59277-89-3 with high quality and best price

Cas:59277-89-3

Min.Order:25 Kilogram

FOB Price: $58.0 / 60.0

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Xi’an Quanao Biotech Co., Ltd. with 18 years experience in plant extract filed. Product grade: Medicine, Health care product, Cosmetics, Food, Beverage, Feed. Hot selling market: Europe, North America, South America, Middle East, Asia Pacifi

Hot sell 99% Acyclovir Powder price cas:59277-89-3

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $19.0 / 39.0

Type:Manufacturers

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Henan Allgreen Chemical Co.,Ltd

The company has a professional R & D team, mature technology, very competitive prices and stable high quality products for customers to order high quality and low price product efforts! Appearance:White crystalline powder Storage:Sealed, dry, m

Acyclovir

Cas:59277-89-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply Acyclovir

Cas:59277-89-3

Min.Order:1

Negotiable

Type:Other

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HANGZHOU CLAKE BIOTECH CO.,LTD

1. GMP AVALIABLE ; 2. IN STOCK 3. FAST REPLY QUALIFED ; EFFICIENCY; RESPONSIBLE Appearance:Yellow or orange-yellow crystalline powder Storage:in cool Package:25kg/drum Application:active pharmaceutical ingredient Transportation:as req

Acyclovir

Cas:59277-89-3

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality 99% Acyclovir 59277-89-3 ISO Producer

Cas:59277-89-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

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COLORCOM LTD.

Colorcom is a global leader in industrial chemical manufacturing and is continuously innovating and transforming to exceed client expectations and industry standards. Colorcom prides itself on superior customer and technical focus, while focusing on

Acyclovir

Cas:59277-89-3

Min.Order:1 Metric Ton

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

Dayangchem’s R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantiti

High purity Acyclovir 98% TOP1 supplier in China

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

inquiry

Sinoway Industrial Co., Ltd.

Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c

Factory Supply Acyclovir powder CAS 59277-89-3

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Trading Company

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Hubei DiBo chemical co., LTD

Name:Acyclovir CAS NO: 59277-89-3 Grade:Medical scientific research and export Molecular formula:C8H11N5O3 Molecular weight: 225.2 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Da

Acyclovir / CAS:59277-89-3 / raw material/ high-quality

Cas:59277-89-3

Min.Order:25 Kilogram

FOB Price: $2.0 / 3.0

Type:Other

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

Acyclovir

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

Our advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be

Acyclovir CAS 59277-89-3

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $48.0 / 58.0

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

TIANFU CHEM--Acyclovir

Cas:59277-89-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

New production CAS 59277-89-3 with best quality

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Hubei Vanz Pharm Co.,Ltd

Product Quick Information : Product Name Acyclovir CAS 59277-89-3 Appearance white powder MF C8H11N5O3 Purity 99% min Usage Pharmaceuticals Storage Keep in cool &am

Factory supply Acyclovir 99% Powder

Cas:59277-89-3

Min.Order:100 Gram

FOB Price: $1.2

Type:Trading Company

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Henan Sinotech Import&Export Corporation

Name: Acyclovir Synonyms: acycloguanosine CAS:59277-89-3 MF: C8H11N5O3 Appearance:White powder Storage:Store in cool and dry place, away from sun light. Package:25kg/drum Application: Synthetic Anti-Infective Drugs Transportation:By sea o

Acyclovir CAS:59277-89-3

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Other

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Hubei Langyou International Trading Co., Ltd

Our Adwantage: 1.We have stock so we can delivery quickly at the very day when receive the payment. 2.Best price, first class service, high successful delivery rate. A discount would be given when you make a large order. 3.High qu

acycloguanosine 59277-89-3 Pharmaceutical Raw material

Cas:59277-89-3

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

HANWAYS CHEMPHARM CO.,LIMITED

We are concentrating on APIs and pharmaceutical intermediates. With in depth knowledge and understanding in this industry, we are indulged in supplying a wide assortments of Acyclovir from Wuhan, Hubei, China. It is made o

Acyclovir

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1,In No Less five years exporting experience. 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Onchem specialized in APIs, chemical intermed

high quality Acycloguanosine 99%

Cas:59277-89-3

Min.Order:1 Kilogram

FOB Price: $10.0

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

It is white crystalline powder, odorless and tasteless. Slightly soluble in water. Melting point 256.5--257℃(methanol). Acute toxicity LD50 mice (mg/kg) : > 10000 oral; 1000 intraperitoneal injection. It is a broad-spectrum antiviral drug contai

Good quality 59277-89-3

Cas:59277-89-3

Min.Order:0 Kilogram

Negotiable

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High-quality Acyclovir CAS 59277-89-3 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in China and

High-quality Acyclovir CAS 59277-89-3

Cas:59277-89-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Terui OP New Material Technology Co., Ltd.

We have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful d

cas 59277-89-3 Acyclovir Chinese manufacturer

Cas:59277-89-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Acyclovir

Cas:59277-89-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Synthetic route

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With sodium hydroxide In water at 85 - 95℃; for 3h;97.5%
With methylamine In water at 23℃; for 1h;93%
With sodium hydroxide92%
1-<(2-hydroxyethoxy)methyl>-5-<(thiocarbamoyl)amino>-1H-imidazole-4-carboxamide
131490-71-6

1-<(2-hydroxyethoxy)methyl>-5-<(thiocarbamoyl)amino>-1H-imidazole-4-carboxamide

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With sodium hydroxide; copper diacetate for 1h; Heating;92%
With sodium hydroxide; copper(II) ion at 100℃; for 1h; Product distribution; further metal ions and reaction conditions investigatet; reaction also with H2O2 / Na2WO4;92%
9-<(2-acetoxyethoxy)methyl>-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine
112233-78-0

9-<(2-acetoxyethoxy)methyl>-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonia In methanol; water at 60℃;91%
With ammonium hydroxide In methanol at 60℃; for 24h;91%
ammonium hydroxide
1336-21-6

ammonium hydroxide

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
In methanol90%
2-amino-6-chloro-9-<(2-hydroxyethoxy)methyl>-9H-purine
81777-49-3

2-amino-6-chloro-9-<(2-hydroxyethoxy)methyl>-9H-purine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With phosphoric acid; adenosine deaminase Ambient temperature; pH=7.5;89%
2,6-diamino-9-{(2-hydroxyethoxy)methyl}purine
59277-86-0

2,6-diamino-9-{(2-hydroxyethoxy)methyl}purine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With phosphoric acid; adenosine deaminase Ambient temperature; pH=7.5;89%
9-(2-trimethylsilyloxyethoxymethyl)guanine
364634-35-5

9-(2-trimethylsilyloxyethoxymethyl)guanine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With acetic acid In water at 80℃; for 2h;85%
9-<(2-acetoxyethoxy)methyl>-2-N-phenylacetylguanine

9-<(2-acetoxyethoxy)methyl>-2-N-phenylacetylguanine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonium hydroxide In methanol for 24h; Ambient temperature;84%
Acetic acid 2-(2-bromo-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester
127218-19-3

Acetic acid 2-(2-bromo-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonia In methanol at 120℃;80%
2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl pyrrolidinophosphate ammonium salt
1400637-35-5

2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl pyrrolidinophosphate ammonium salt

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; pH=12;A 80%
B n/a
2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl morpholinophosphate ammonium salt
1400637-36-6

2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl morpholinophosphate ammonium salt

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; for 120h; pH=12;A 80%
B n/a
N-(2-morpholinoethyl)-2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl phosphoramidate ammonium salt
1400637-37-7

N-(2-morpholinoethyl)-2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl phosphoramidate ammonium salt

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; pH=12;A 80%
B n/a
N,N-dipropyl-2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl phosphoramidate ammonium salt

N,N-dipropyl-2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl phosphoramidate ammonium salt

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; pH=12;A 80%
B n/a
9-(2-hydroxyethoxymethyl)guanine phosphoromono-N,N-dimethylaminoethylamidate
1400637-39-9

9-(2-hydroxyethoxymethyl)guanine phosphoromono-N,N-dimethylaminoethylamidate

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; pH=12;A 80%
B n/a
9-(2-hydroxyethoxymethyl)guanine phosphoromono-3-dimethylamino-1-propylamidate
1400637-40-2

9-(2-hydroxyethoxymethyl)guanine phosphoromono-3-dimethylamino-1-propylamidate

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; pH=12;A 80%
B n/a
N-hexyl-2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl phosphoramidate ammonium salt
1400637-42-4

N-hexyl-2-[(2-amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]ethyl phosphoramidate ammonium salt

A

acycloguanosine
59277-89-3

acycloguanosine

B

acyclovir monophosphate

acyclovir monophosphate

Conditions
ConditionsYield
With potassium chloride; potassium hydroxide In water at 25℃; pH=12;A 80%
B n/a
1,3-DIOXOLANE
646-06-0

1,3-DIOXOLANE

2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

pyrographite
7440-44-0

pyrographite

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With trimethylsilyl trifluoromethanesulfonate; acetic acid; 1,1,1,3,3,3-hexamethyl-disilazane78%
With trifluorormethanesulfonic acid; 1,1,1,3,3,3-hexamethyl-disilazane In water; acetic acid73%
With ammonium hydroxide; sodium hydroxide; trifluorormethanesulfonic acid; acetic acid; 1,1,1,3,3,3-hexamethyl-disilazane In water; toluene72%
With trifluorormethanesulfonic acid; acetic acid; 1,1,1,3,3,3-hexamethyl-disilazane In methanol; water66.6%
9-(benzoyloxyethoxymethyl)guanine

9-(benzoyloxyethoxymethyl)guanine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonia In methanol75%
9-(2-trimethylsilylethoxymethyl)guanine

9-(2-trimethylsilylethoxymethyl)guanine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With acetic acid In water69%
acyclovir P-(O-isopropyl) hydrogenphosphonate
661465-32-3

acyclovir P-(O-isopropyl) hydrogenphosphonate

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With human blood serum In water at 37℃; for 72h; Product distribution; Further Variations:; Reagents;52%
1-(2-amino-6-chloro-purin-9-ylmethoxy)-2-benzoyloxy-ethane
59277-92-8

1-(2-amino-6-chloro-purin-9-ylmethoxy)-2-benzoyloxy-ethane

2-hydroxyethanethiol
60-24-2

2-hydroxyethanethiol

A

acycloguanosine
59277-89-3

acycloguanosine

B

9-(2-hydroxymethoxymethyl)guanine

9-(2-hydroxymethoxymethyl)guanine

Conditions
ConditionsYield
In methanol; methanolic sodium methylate; waterA n/a
B 45%
9-<(2-hydroxyethoxy)methyl>-2-(methylthio)hypoxanthine
75128-77-7

9-<(2-hydroxyethoxy)methyl>-2-(methylthio)hypoxanthine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonia In ethanol at 140℃; for 60h;39%
In ethanol; ammonia15 mg (39%)
acyclovir hydrogenphosphonate
157722-20-8

acyclovir hydrogenphosphonate

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With human blood serum In water at 37℃; for 72h; Product distribution; Further Variations:; Reagents;18%
2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

acetic anhydride
108-24-7

acetic anhydride

A

acycloguanosine
59277-89-3

acycloguanosine

B

7-(2-Hydroxyethoxymethyl)guanine
91702-61-3

7-(2-Hydroxyethoxymethyl)guanine

Conditions
ConditionsYield
With sodium hydroxide; toluene-4-sulfonic acid 1.) 100 deg C, 20 h, 2.) room temperature, overnight; Yield given. Multistep reaction;A n/a
B 0.5%
(2-benzoyloxyethyl)oxymethyl chloride
58305-05-8

(2-benzoyloxyethyl)oxymethyl chloride

2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonium sulfate; tetrabutyl ammonium fluoride 1.) hexamethyldisilazane, reflux, 24 h; 2.) THF/benzene, reflux, 3 h; Yield given. Multistep reaction;
2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

2-chloroethyl chloromethyl ether
1462-33-5

2-chloroethyl chloromethyl ether

A

acycloguanosine
59277-89-3

acycloguanosine

B

9-<<2-chloroethoxy>methyl>guanine
127302-85-6

9-<<2-chloroethoxy>methyl>guanine

Conditions
ConditionsYield
With ammonium sulfate; tetrabutyl ammonium fluoride 1.) hexamethyldisilazane, reflux, 24 h; 2.) THF/benzene, reflux, 3 h; Yield given. Multistep reaction. Yields of byproduct given;
With ammonium sulfate; tetrabutyl ammonium fluoride 1.) hexamethyldisilazane, reflux, 24 h; 2.) THF/benzene, reflux, 4 h; Yield given. Multistep reaction. Yields of byproduct given;
2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

1-bromo-2-(chloromethoxy)ethane
1462-35-7

1-bromo-2-(chloromethoxy)ethane

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With ammonium sulfate; tetrabutyl ammonium fluoride 1.) hexamethyldisilazane, reflux, 24 h; 2.) THF/benzene, reflux, 3 h; Yield given. Multistep reaction;
9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With methylamine at 80℃; for 0.5h;
With Dulbecco's Modified Phosphite-Buffer Saline; SIRC cell lysate at 34℃; pH=7.4; Kinetics; Further Variations:; Reagents;
acycloguanosine
59277-89-3

acycloguanosine

acetic anhydride
108-24-7

acetic anhydride

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one
110104-37-5

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With dmap for 120h; Ambient temperature;98%
acycloguanosine
59277-89-3

acycloguanosine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

N'-[9-(2-hydroxy-ethoxymethyl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-N,N-dimethyl-formamidine

N'-[9-(2-hydroxy-ethoxymethyl)-6-oxo-6,9-dihydro-1H-purin-2-yl]-N,N-dimethyl-formamidine

Conditions
ConditionsYield
With N,N-dimethyl-formamide Condensation;98%
acycloguanosine
59277-89-3

acycloguanosine

[poly(ethylene glycol)](NHCH2CH2COOH)2, MW: 1500 D

[poly(ethylene glycol)](NHCH2CH2COOH)2, MW: 1500 D

[poly(ethylene glycol)](NH-CH2CH2COO-aciclovir)2

[poly(ethylene glycol)](NH-CH2CH2COO-aciclovir)2

Conditions
ConditionsYield
With dmap; triethylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 20℃; for 72h;98%
acycloguanosine
59277-89-3

acycloguanosine

2-(2,2-dimethyl-3-trityloxypropanoyl)sulfanylethoxyphosphinic acid
1036914-97-2

2-(2,2-dimethyl-3-trityloxypropanoyl)sulfanylethoxyphosphinic acid

9-(2-hydroxy-ethoxymethyl)-guanin-5'-yl-0-(triphenylmethyloxy-tert-butyl-5-acyl-2-thioethyl) H-phosphonate
1037071-44-5

9-(2-hydroxy-ethoxymethyl)-guanin-5'-yl-0-(triphenylmethyloxy-tert-butyl-5-acyl-2-thioethyl) H-phosphonate

Conditions
ConditionsYield
With pivaloyl chloride In pyridine at -15 - 20℃; for 2h;98%
acycloguanosine
59277-89-3

acycloguanosine

capric anhydride
2082-76-0

capric anhydride

2-amino-9-[(2-decanoyloxy)ethyl-oxy-methyl]-1,9-dihydro-6H-purin-6-one
1360928-42-2

2-amino-9-[(2-decanoyloxy)ethyl-oxy-methyl]-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide for 0.166667h; Inert atmosphere;98%
acycloguanosine
59277-89-3

acycloguanosine

myristic anhydride
626-29-9

myristic anhydride

2-amino-9-[(2-tetradecanoyloxy)ethyloxy-methyl]-1,9-dihydro-6H-purin-6-one
866215-87-4

2-amino-9-[(2-tetradecanoyloxy)ethyloxy-methyl]-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide for 0.166667h; Inert atmosphere;98%
acycloguanosine
59277-89-3

acycloguanosine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

9-<<2-<(tert-butyl)dimethylsiloxy>ethoxy>methyl>guanidine

9-<<2-<(tert-butyl)dimethylsiloxy>ethoxy>methyl>guanidine

Conditions
ConditionsYield
With 1H-imidazole at 25℃; for 48h;97%
acycloguanosine
59277-89-3

acycloguanosine

tert-butyldimethylsilyl chloride
18162-48-6

tert-butyldimethylsilyl chloride

2-amino-9-[2-(tert-butyldimethylsilyloxy)ethoxymethyl]-1,9-dihydropurin-6-one
139767-68-3

2-amino-9-[2-(tert-butyldimethylsilyloxy)ethoxymethyl]-1,9-dihydropurin-6-one

Conditions
ConditionsYield
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 48h;97%
With 1H-imidazole In N,N-dimethyl-formamide at 20℃;87%
With 1H-imidazole In N,N-dimethyl-formamide at 23℃; for 5h;79%
acycloguanosine
59277-89-3

acycloguanosine

N,N-dimethyl-formamide dimethyl acetal
4637-24-5

N,N-dimethyl-formamide dimethyl acetal

N'-(9-((2-hydroxyethoxy)-methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide
100699-59-0

N'-(9-((2-hydroxyethoxy)-methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 20℃; for 24h;97%
In N,N-dimethyl-formamide at 20℃;
acycloguanosine
59277-89-3

acycloguanosine

n-hexanoic anhydride
2051-49-2

n-hexanoic anhydride

2-amino-9-[(2-hexanoyloxy)ethyl-oxy-methyl]-1,9-dihydro-6H-purin-6-one

2-amino-9-[(2-hexanoyloxy)ethyl-oxy-methyl]-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide for 0.166667h; Inert atmosphere;97%
dmap In N,N-dimethyldecanoamide at 25℃; for 48h; Product distribution / selectivity; Inert atmosphere;90%
acycloguanosine
59277-89-3

acycloguanosine

lauric anhydride
645-66-9

lauric anhydride

2-amino-9-[(2-dodecanoyloxy)ethyl-oxymethyl]-1,9-dihydro-6H-purin-6-one
140900-50-1

2-amino-9-[(2-dodecanoyloxy)ethyl-oxymethyl]-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide for 0.166667h; Inert atmosphere;97%
butanoic acid anhydride
106-31-0

butanoic acid anhydride

acycloguanosine
59277-89-3

acycloguanosine

2-amino-9-[(2-butanoyloxy)ethyl-oxy-methyl]-1,9-dihydro-6H-purin-6-one
64843-83-0

2-amino-9-[(2-butanoyloxy)ethyl-oxy-methyl]-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide for 0.166667h; Inert atmosphere;96%
With pyridine; dmap In N,N-dimethyl-formamide for 36h;
acycloguanosine
59277-89-3

acycloguanosine

C20H33N3O9S

C20H33N3O9S

(S)-2-((S)-2-tert-butoxycarbonylaminothiopropionylamino)succinic acid 4-[2-(2-amino-6-oxo-1,6-dihydropurin-9-ylmethoxy)ethyl] ester 1-tert-butyl ester

(S)-2-((S)-2-tert-butoxycarbonylaminothiopropionylamino)succinic acid 4-[2-(2-amino-6-oxo-1,6-dihydropurin-9-ylmethoxy)ethyl] ester 1-tert-butyl ester

Conditions
ConditionsYield
Stage #1: C20H33N3O9S With dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 0℃; for 1h; Inert atmosphere;
Stage #2: acycloguanosine With dmap In N,N-dimethyl-formamide at 0 - 20℃; for 24h; Inert atmosphere;
96%
acycloguanosine
59277-89-3

acycloguanosine

2-amino-8-bromo-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one
81475-44-7

2-amino-8-bromo-9-[(2-hydroxyethoxy)methyl]-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With bromine In water at 20℃;95%
With bromine In water at 20℃; for 0.5h;87%
With bromine In water
acycloguanosine
59277-89-3

acycloguanosine

acetic anhydride
108-24-7

acetic anhydride

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

Conditions
ConditionsYield
With dmap In dimethyl sulfoxide for 0.166667h; Inert atmosphere;95%
With dmap In DMF (N,N-dimethyl-formamide) at 20℃; for 18h;91%
With pyridine at 40℃; for 2h;78%
With pyridine; dmap In N,N-dimethyl-formamide for 36h;
With dmap
acycloguanosine
59277-89-3

acycloguanosine

divinyl butanedioate
13416-90-5

divinyl butanedioate

succinic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester vinyl ester

succinic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester vinyl ester

Conditions
ConditionsYield
With Candida antarctica lipase acrylic resin In acetone at 50℃; for 12h;95%
acycloguanosine
59277-89-3

acycloguanosine

N,N-dimethyl-formamide
68-12-2, 33513-42-7

N,N-dimethyl-formamide

N'-(9-((2-hydroxyethoxy)-methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide
100699-59-0

N'-(9-((2-hydroxyethoxy)-methyl)-6-oxo-6,9-dihydro-1H-purin-2-yl)-N,N-dimethylformimidamide

Conditions
ConditionsYield
In methanol at 20℃; for 96h;95%
phthalic anhydride
85-44-9

phthalic anhydride

acycloguanosine
59277-89-3

acycloguanosine

C16H15N5O6

C16H15N5O6

Conditions
ConditionsYield
With triethylamine In N,N-dimethyl-formamide at 60℃; for 12h;94.5%
acycloguanosine
59277-89-3

acycloguanosine

1-<(tert-butyloxy)carbonylamino>cyclopropane-1-carboxylic acid
88950-64-5

1-<(tert-butyloxy)carbonylamino>cyclopropane-1-carboxylic acid

1-tert-butoxycarbonylamino-cyclopropanecarboxylic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester
915725-88-1

1-tert-butoxycarbonylamino-cyclopropanecarboxylic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

Conditions
ConditionsYield
With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine In N,N-dimethyl-formamide at 20℃;94%
With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine In N,N-dimethyl-formamide at 20℃;93.7%
acycloguanosine
59277-89-3

acycloguanosine

acyclovir hydrochloride

acyclovir hydrochloride

Conditions
ConditionsYield
With hydrogenchloride In isopropyl alcohol at 20℃; for 0.5h;94%
acycloguanosine
59277-89-3

acycloguanosine

DL-N,N-di-CBZ-lysine
55592-85-3

DL-N,N-di-CBZ-lysine

2,6-bis-benzyloxycarbonylamino-hexanoic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

2,6-bis-benzyloxycarbonylamino-hexanoic acid 2-(2-amino-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In N,N-dimethyl-formamide at 20℃; for 24h;91%
acycloguanosine
59277-89-3

acycloguanosine

2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With sodium hydroxide In water90%
acycloguanosine
59277-89-3

acycloguanosine

diiodo(2,9-dimethyl-1,10-phenanthroline-κ(2)N,N')platinum(II)
31233-28-0

diiodo(2,9-dimethyl-1,10-phenanthroline-κ(2)N,N')platinum(II)

dichloromethane
75-09-2

dichloromethane

[(9-(2-hydroxyethoxymethyl)-guanine)(2,9-dimethyl-1,10-phenantroline)PtI)I*5CH2Cl2

[(9-(2-hydroxyethoxymethyl)-guanine)(2,9-dimethyl-1,10-phenantroline)PtI)I*5CH2Cl2

Conditions
ConditionsYield
In methanol; dichloromethane soln. PtI2(Me2phen) (CH2Cl2) treated with soln of acyclovir (CH3OH); stirring for one day; solvent evapd. vac.; diethyl ether added; ppt. filtered; washed (ether);dried vac.; elem. anal.;90%
acycloguanosine
59277-89-3

acycloguanosine

diiodo(2,9-dimethyl-1,10-phenanthroline-κ(2)N,N')platinum(II)
31233-28-0

diiodo(2,9-dimethyl-1,10-phenanthroline-κ(2)N,N')platinum(II)

dichloromethane
75-09-2

dichloromethane

[(9-(2-hydroxyethoxymethyl)-guanine)2(2,9-dimethyl-1,10-phenantroline)Pt(II)]I2*CH2Cl2

[(9-(2-hydroxyethoxymethyl)-guanine)2(2,9-dimethyl-1,10-phenantroline)Pt(II)]I2*CH2Cl2

Conditions
ConditionsYield
In methanol; dichloromethane soln. PtI2(Me2phen) (CH2Cl2/CH3OH 1:1) treated with acyclovir; stirring for 2 h; solvent evapd. vac.; suspended (H2O); stirred over night; soln. filtered; evapd. vac.; elem. anal.;90%
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