Dayangchem's R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. DayangChem can provide different quantities
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inquiryProduct description: Product name 4-Chloromethyl-5-methyl-1,3-dioxol-2-one CAS number 80841-78-7 Assay ≥98% Appearance White powder Capacity 50mt/year Application Olmesartan
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inquiryItems Standard Result Assay (Ursolic acid) 98%min 98.22% -----------------------------------------------------------------------------------------------------------
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inquiryUnique advantages for Olmesartan medoxomil intermediate Cas80841-78-7 Guaranteed the purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Pale yellow transparent liquid Storage:cool dry place Packa
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inquiryGood quality Good price Promptly delivery Appearance:white powder Storage:dry dondition Package:According to the demand of customer Application:intermediate Transportation:According to the demand of customer Port:shanghai
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inquiry4-Chloromethyl-5-methyl-1,3-dioxol-2-one (DMDO-Cl) CAS NO.:80841-78-7 Name 4-Chloromethyl-5-methyl-1,3-dioxol-2-one Synonyms DMDO-Cl
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inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
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inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
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inquiry1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99.0% Appearan
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inquiryHebei Yanxi Chemical Co., Ltd. is a professional research, development and production of lead acetate benzene acetamide enterprise backbone members by local well-known entrepreneurs and professional senior engineers in the party's "low car
Cas:80841-78-7
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inquiryName:4-Cloromethyl-5-methyl-1,3-dioxol-2-one CAS NO:80841-78-7 Grade:As an intermediate of irbesartan and olmesartan ester Product Quality 12 years of chemical raw materials Mature operation of the industry System stability Data storage Secu
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inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so
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inquiryOur advantages: 1, High quality with competitive price: 1) Standard:BP/USP/EP/Enterprise standard 2) All Purity≥99% 3) We are manufacturer and can provide high quality products with factory price. 2, Fast and safe delivery 1) Parcel can be
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inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
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inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
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inquiry1. Product advantages High purity, all above 98.5%, no impurities after dissolution We will test each batch to ensure quality OEM and private brand services designed for free Various cap colors available We can also provide MT1 peptide powd
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inquiryName: 4-Cloromethyl-5-methyl-1,3-dioxol-2-one Synonyms: OLM 45 CAS: 80841-78-7 MF: C5H5ClO3 Appearance:Colorless clear liquid Storage:Preserve in well-closed, light-resistant and airtight containers. Package:25kg/drum Application:Organic intermedi
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inquiryAppearance:Light yellow liquid Storage:ln stock Package:25kg/Barrel Application:Chemicals Transportation:Express/Sea/Air Port:Any port in china
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inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is
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inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
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inquiryHangzhou Huarong Pharm Co., Ltd. established since 2009 , has been always focusing on supplying products and services to our clients in the field of small molecule drug. Huarong Pharm has built platforms for the research, development and manufac
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inquiryProduct Name: 4-Cloromethyl-5-methyl-1,3-dioxol-2-one CAS: 80841-78-7 MF: C5H5ClO3 MW: 148.54 EINECS: 617-178-6 Mol File: 80841-78-7.mol 4-Cloromethyl-5-methyl-1,3-dioxol-2-one Structure 4-Cloromethyl-5-methyl-1,3-dioxol-2-one Che
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inquiry4-Cloromethyl-5-methyl-1,3-dioxol-2-one CAS: 80841-78-7 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high
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inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
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inquiry4-Cloromethyl-5-methyl-1,3-dioxol-2-one CAS# 80841-78-7 MF: C5H5O3Cl Appearance: light yellow transparent liquid Application: Used as pharmacy in… ISO9001 Appearance:Clear yellowish liquid Storage:Store in dry and cool place with g
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inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
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inquiry4,5-Dimethyl-1,3-dioxole-2-one
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With chlorine In 1,2-dichloro-ethane for 0.5h; Solvent; Reagent/catalyst; Reflux; Molecular sieve; | 89.3% |
With N-chloro-succinimide In tetrachloromethane for 80h; Ambient temperature; Irradiation; | 9.2% |
With chlorine; copper 1.) dichloromethane, 90 min, reflux, 2.) dichloromethane, 2 h, reflux; Yield given. Multistep reaction; | |
With sulfuryl dichloride In dichloromethane | |
With N-chloro-succinimide; dibenzoyl peroxide at 90℃; for 5.5h; Temperature; Solvent; Large scale; | 326 g |
4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
at 75 - 80℃; for 4h; | 87% |
4,5-Dimethyl-1,3-dioxole-2-one
A
4-chloromethyl-5-methyl-1,3-dioxol-2-one
B
4-chloro-4-methyl-5-methylene-1,3-dioxolane-2-one
C
4,5-dimethyl-4,5-dichloro-1,3-dioxolan-2-one
Conditions | Yield |
---|---|
With chlorine In dichloromethane at 43 - 45℃; Product distribution; further solvents; | A 1.4 % Chromat. B 87.5 % Chromat. C n/a |
methyl (7S)-6-N-((2′S,4′R)-4′-(cyclopropylmethyl)piperidine-2′-carbonyl)-7-deoxy-7-(4-(pyrimidin-5-yl)phenylthio)-α-thiolincosaminide
4-chloromethyl-5-methyl-1,3-dioxol-2-one
methyl 6-N-((2S,4R)-4-cyclopropylmethyl-1-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl)pipecoloyl)-7-deoxy-7-epi-7-(4-(pyrimidin-5-yl)phenylthio)-1-thio-α-lincosamide
Conditions | Yield |
---|---|
With sodium carbonate In N,N-dimethyl-formamide at 20℃; for 1.5h; | 100% |
Conditions | Yield |
---|---|
With sodium hydrogencarbonate; potassium iodide; benzyltri(n-butyl)ammonium chloride In tetrahydrofuran at 30 - 55℃; for 5h; | 99.11% |
With sodium hydrogencarbonate; potassium iodide; tetrabutyl-ammonium chloride In acetone at 50℃; for 4h; Conversion of starting material; | 94.2% |
With benzyltri(n-butyl)ammonium chloride; sodium hydrogencarbonate; potassium iodide In tetrahydrofuran at 30 - 55℃; for 6h; Product distribution / selectivity; | 70% |
With sodium hydrogencarbonate; benzyltri(n-butyl)ammonium chloride In tetrahydrofuran at 50℃; for 4h; Conversion of starting material; | 36.7% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; for 48h; | 99% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With sodium iodide In N,N-dimethyl-formamide at 40℃; for 1h; Inert atmosphere; | 97% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; for 2h; | 97% |
ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazole-5-carboxylate
4-chloromethyl-5-methyl-1,3-dioxol-2-one
trityl olmesartan medoxomil
Conditions | Yield |
---|---|
Stage #1: ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazole-5-carboxylate With lithium hydroxide monohydrate In tetrahydrofuran at 20℃; for 18h; Large scale; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 20 - 40℃; for 2h; Large scale; | 96.5% |
Stage #1: ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazole-5-carboxylate With sodium hydroxide In ethanol at 20 - 25℃; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one With potassium carbonate In N,N-dimethyl acetamide at 45 - 50℃; for 4h; | 88% |
Stage #1: ethyl 4-(2-hydroxypropan-2-yl)-2-propyl-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazole-5-carboxylate With sodium hydroxide In acetone at 50 - 60℃; for 5h; Green chemistry; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one With potassium iodide In acetone at 20 - 60℃; for 1h; Green chemistry; | 85.8% |
4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(1-(triphenylmethyl)tetrazol-5-yl)phenyl)phenyl)methylimidazole-5-carboxylic acid
4-chloromethyl-5-methyl-1,3-dioxol-2-one
trityl olmesartan medoxomil
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl acetamide at 0 - 45℃; for 3h; Inert atmosphere; | 94% |
Stage #1: 4-(1-hydroxy-1-methylethyl)-2-propyl-1-(4-(2-(1-(triphenylmethyl)tetrazol-5-yl)phenyl)phenyl)methylimidazole-5-carboxylic acid With potassium carbonate In N,N-dimethyl-formamide at 20℃; Autoclave; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one With potassium iodide In N,N-dimethyl-formamide at 20℃; | 91.6% |
With potassium carbonate; potassium iodide In acetone Product distribution / selectivity; Reflux; | |
In water; acetone at 48 - 52℃; for 5h; Product distribution / selectivity; | |
With potassium bromide In N,N-dimethyl acetamide at 15 - 50℃; for 8.6h; Time; Green chemistry; | 23.2 g |
sodium 4-(2-hydroxypropan-2-yl)-2-propyl-1-({2'-[1-(triphenylmethyl)-1H-1,2,3,4-tetrazol-5-yl]-[1,1'-biphenyl]-4-yl}methyl)-1H-imidazole-5-carboxylate
4-chloromethyl-5-methyl-1,3-dioxol-2-one
trityl olmesartan medoxomil
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl acetamide at 5 - 10℃; for 4h; | 93% |
With sodium carbonate In N,N-dimethyl acetamide at 45 - 50℃; Large scale reaction; | 80% |
With potassium carbonate In N,N-dimethyl-formamide at 0 - 85℃; for 4h; | |
With sodium iodide In N,N-dimethyl-formamide at 55℃; for 7.5h; | 45g |
With iodine; sodium carbonate at 50℃; under 75.0075 Torr; Inert atmosphere; Large scale; | 53.6 kg |
fenofibric acid
4-chloromethyl-5-methyl-1,3-dioxol-2-one
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl-2‑(4‑(4-chlorobenzoyl)phenoxy)-2-methylpropanoate
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl acetamide at 65℃; | 93% |
With sodium carbonate In N,N-dimethyl acetamide at 30℃; for 17h; Inert atmosphere; | 83% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; | 93% |
N-hydroxyphthalimide
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
Stage #1: N-hydroxyphthalimide With sodium hydride In N,N-dimethyl-formamide at 0℃; for 0.0833333h; Inert atmosphere; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one In N,N-dimethyl-formamide at 0 - 70℃; Inert atmosphere; | 92% |
Stage #1: N-hydroxyphthalimide With sodium hydride In N,N-dimethyl-formamide at 0℃; Inert atmosphere; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one In N,N-dimethyl-formamide at 70℃; for 1h; Inert atmosphere; | 92% |
potassium 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl]biphenyl-4-yl]methyl]imidazole-5-carboxylate
4-chloromethyl-5-methyl-1,3-dioxol-2-one
trityl olmesartan medoxomil
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl acetamide at 0 - 45℃; for 3h; | 91% |
With potassium iodide In butanone at 50℃; for 7.5h; | 86% |
With potassium iodide In butanone at 50℃; for 20h; | 84.4% |
Stage #1: potassium 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[1-(triphenylmethyl)-1H-tetrazol-5-yl]biphenyl-4-yl]methyl]imidazole-5-carboxylate With sodium carbonate; potassium iodide In acetone at 25 - 30℃; for 0.166667h; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one In acetone at 45 - 50℃; for 12h; | 76 g |
With iodine; potassium carbonate at 50℃; under 75.0075 Torr; Inert atmosphere; Large scale; | 54.06 kg |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
atovaquone
3-(5-methyl-2-oxo-1,3-dioxol-4-yl)methyloxy-2-trans-[(4-chlorophenyl)cyclohexyl][1,4]naphthoquinone
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 60 - 65℃; Concentration; | 90% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate In acetonitrile at 60 - 65℃; Concentration; | 90% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2'-(2-triphenylmethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl-1H-imidazole-5-carboxylate
olmesartan medoxomil
Conditions | Yield |
---|---|
Stage #1: ethyl 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2'-(2-triphenylmethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl-1H-imidazole-5-carboxylate With sodium hydroxide In N,N-dimethyl acetamide at 10 - 15℃; for 8h; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one With potassium carbonate In N,N-dimethyl acetamide at 0 - 65℃; for 10h; | 90% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
(5-methyl-2-oxo-1,3-dioxolen-4-yl)methyl4-(1-hydroxy-1-methylethyl)-2-propyl-1-[2′-(2-triphenylmethyl-2H-tetrazol-5-yl)biphenyl-4-yl]methyl-1H-imidazole-5-carboxylate
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl acetamide at 20 - 50℃; for 4h; | 88% |
Stage #1: 4-(1-hydroxy-1-methylethyl)-2-propyl-1-[[2'-[2-(triphenylmethyl)-2H-tetrazol-5yl]biphenyl-4-yl]methyl]imidazole-5-carboxylic acid lithium salt With triethylamine In ISOPROPYLAMIDE at 20℃; for 0.5h; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one In ISOPROPYLAMIDE at 10 - 55℃; for 4h; | 75% |
trityl chloride
4-chloromethyl-5-methyl-1,3-dioxol-2-one
methyl 2-ethoxy-1-((2′-(N′-hydroxycarbamimidoyl)-biphenyl-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate
(5-methyl-2-oxo-2H-1,3-dioxol-4yl)methyl 2-ethoxy-1-[(4-(2-[N-hydroxy-carbamimidoyl]phenyl)phenyl)-methyl]-1H-1,3-benzodiazole-7-carboxylate
Conditions | Yield |
---|---|
Stage #1: trityl chloride; methyl 2-ethoxy-1-((2′-(N′-hydroxycarbamimidoyl)-biphenyl-4-yl)methyl)-1H-benzo[d]imidazole-7-carboxylate With triethylamine In dichloromethane at 25 - 30℃; for 16h; Large scale; Stage #2: With sodium hydroxide In tetrahydrofuran; methanol; water at 25 - 45℃; for 8h; Large scale; Stage #3: 4-chloromethyl-5-methyl-1,3-dioxol-2-one Reagent/catalyst; Temperature; Large scale; Further stages; | 88% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl iodide
Conditions | Yield |
---|---|
With sodium iodide In acetonitrile at 30℃; for 0.5h; | 87% |
With sodium iodide In butanone at 20 - 60℃; for 1.5h; | 77% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 60℃; for 1h; | 87% |
(4S)-3-oxo-8-[2-(8-tert-butoxycarbonyl-5,6,7,8-tetrahydroimidazo[1,2-a]-pyrimidin-2-yl)ethoxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepin-4-acetic acid
4-chloromethyl-5-methyl-1,3-dioxol-2-one
(5-methyl-2-oxo-[1,3]dioxolen-4-yl)methyl (4S)-3-oxo-8-[2-(8-tert-butoxycarbonyl-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidin-2-yl)ethoxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepin-4-acetate
Conditions | Yield |
---|---|
Stage #1: (4S)-3-oxo-8-[2-(8-tert-butoxycarbonyl-5,6,7,8-tetrahydroimidazo[1,2-a]-pyrimidin-2-yl)ethoxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepin-4-acetic acid; 4-chloromethyl-5-methyl-1,3-dioxol-2-one With sodium hydrogencarbonate In N,N-dimethyl-formamide for 2.5h; Cooling with ice; Inert atmosphere; Stage #2: With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 6h; Stage #3: 4-chloromethyl-5-methyl-1,3-dioxol-2-one In N,N-dimethyl-formamide at 20℃; for 15.5h; | 86% |
Stage #1: (4S)-3-oxo-8-[2-(8-tert-butoxycarbonyl-5,6,7,8-tetrahydroimidazo[1,2-a]-pyrimidin-2-yl)ethoxy]-2-(2,2,2-trifluoroethyl)-2,3,4,5-tetrahydro-1H-2-benzazepin-4-acetic acid With sodium hydrogencarbonate In water; N,N-dimethyl-formamide for 2.5h; Inert atmosphere; Cooling with ice; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one With potassium carbonate at 20℃; for 21.5h; | 86% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate; potassium iodide In N,N-dimethyl-formamide at 50℃; for 1h; | 86% |
Conditions | Yield |
---|---|
With sodium carbonate; sodium iodide In N,N-dimethyl acetamide at 35℃; for 3h; Reagent/catalyst; Solvent; | 85.9% |
5-(((tert-butoxycarbonyl)amino)methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinic acid
4-chloromethyl-5-methyl-1,3-dioxol-2-one
(5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 5-{[(tert-butoxycarbonyl)amino]methyl}-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate
Conditions | Yield |
---|---|
With potassium carbonate In DMF (N,N-dimethyl-formamide) at 20℃; for 1h; | 85% |
(6-{(pyridin-2-ylsulfonyl)[4-(thiazol-2-yl)benzyl]aminomethyl}pyridin-2-ylamino)-acetic acid
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; for 15h; | 84% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
Stage #1: (E)-1-[[2′-[[N-(2-chlorotrityl)]-1H-tetrazol-5-yl]biphenyl-4-yl]methyl]imidazole-4-acrylic acid With potassium carbonate In N,N-dimethyl acetamide at 20℃; for 0.5h; Inert atmosphere; Stage #2: 4-chloromethyl-5-methyl-1,3-dioxol-2-one In N,N-dimethyl acetamide for 4h; Inert atmosphere; | 84% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 20℃; | 84% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With chloro-trimethyl-silane In dichloromethane at 20℃; Further stages; | 84% |
4-chloromethyl-5-methyl-1,3-dioxol-2-one
p-Chlorothiophenol
4-(4-Chlorophenyl)thiomethyl-5-methyl-1,3-dioxol-2-one
Conditions | Yield |
---|---|
With triethylamine In dichloromethane | 83% |
With triethylamine In dichloromethane; ethyl acetate |
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