Our Services 1. New Molecules R&D 2. Own test center HPLC NMR GC LC-MS 3. API and Intermediates from China reputed manufacturers 4. Documents support COA MOA MSDS DMF open part Our advantages 1. Government awarded company. Top 100 enter
Why is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:134678-17-4
Min.Order:1 Kilogram
FOB Price: $1.0 / 999.0
Type:Trading Company
inquiryProduct informations Product Name 4-Amino-1-(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl)pyrimidin-2(1H)-one CAS No.
Cas:134678-17-4
Min.Order:1 Gram
FOB Price: $8.0
Type:Lab/Research institutions
inquiry1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; ...... Appearance:White to off-white solid Storage:Freezer Package:1kg/foil bag
Cas:134678-17-4
Min.Order:1 Kilogram
FOB Price: $180.0 / 230.0
Type:Trading Company
inquiryWe can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C
Cas:134678-17-4
Min.Order:1 Gram
Negotiable
Type:Manufacturers
inquiry1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s
Cas:134678-17-4
Min.Order:1 Gram
FOB Price: $0.1
Type:Manufacturers
inquiryGMP certificated Specification:USp high purity Appearance:whilt powder Storage:cool and dryer Package:durm Application:API Transportation:by sea or by ar Port:shandong
Cas:134678-17-4
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryDayangChem exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product s
Cas:134678-17-4
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
chengdu and import and export trade co., LTD., who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do res
Cas:134678-17-4
Min.Order:1000 Gram
FOB Price: $500.0
Type:Trading Company
inquiryName:Lamivudine CAS NO: 134678-17-4 Grade:Medical scientific research and export Molecular formula:C8H11N3O3S Molecular weight:229.2562 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability D
Cas:134678-17-4
Min.Order:25 Kilogram
FOB Price: $1.0 / 2.0
Type:Other
inquiryLamivudine Basic information New antiviral drug Methods of production What kind of patients suitable for use Lamivudine Zidovudine Pharmacokinetics drug withdrawal Adverse reactions and side effects Disabling condition Chemical property Uses Pro
Our company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:134678-17-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:134678-17-4
Min.Order:1 Kilogram
FOB Price: $1.0 / 10.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:134678-17-4
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryOur Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We
Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&
Cas:134678-17-4
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiry134678-17-4;131086-21-0 Lamivudine product Name Lamivudine Synonyms 2(1H)-Pyrimidinone,4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-,(2R-
Appearance:White powder Storage:Room temperature Package:25kg/drum Application:API, New antiviral drugs Transportation:Express/Air/Sea Port:Any port in china
Cas:134678-17-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry1.Good capacity; 2.Safe deliver 3. High quality with best price Appearance:White Powder Storage:Dry and cool place Package:100g/ bag, 2 kg/ bag, 25kg/ carton or as required Application:For Pharmaceutical Intermediates Transportation:By DHL, TNT
Cas:134678-17-4
Min.Order:10 Gram
Negotiable
Type:Other
inquiry1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized
Cas:134678-17-4
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese
Cas:134678-17-4
Min.Order:1 Kilogram
FOB Price: $86.0 / 100.0
Type:Trading Company
inquiryLamivudine CAS: 134678-17-4 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in high quality organic intermediate
Cas:134678-17-4
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryWe have overseas warehouses in California, New Laredo Mexico, Vancouver Canada, Amsterdam Netherlands, and Melbourne Australia. Overseas warehouses can provide some of the best-selling products. We look forward to the cooperation of local powerful
Cas:134678-17-4
Min.Order:0 Metric Ton
Negotiable
Type:Trading Company
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France etc. 3) OEM/ODM Available;
Cas:134678-17-4
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Shanghai SOYOUNG onsite assessment conducted by Bureau Veritas commissioned at June 2018. Assessed Supplier of Shanghai SOYOUNG is a faithful and professional supplier of health raw materials in pharmacy, food, cosmetic and other fields for many ye
Cas:134678-17-4
Min.Order:25 Kilogram
FOB Price: $220.0
Type:Lab/Research institutions
inquiryAppearance:white powder Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:Common products:Sea/Air/Courie
Cas:134678-17-4
Min.Order:100 Metric Ton
Negotiable
Type:Lab/Research institutions
inquiryUSP Appearance:White or off- white crystalline powder Storage:Room temperature Package:25kg/drum or as required Application:used in medicine Transportation:by sea by air express Port:China main port
Cas:134678-17-4
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquirylamivudine
Conditions | Yield |
---|---|
With sodium tetrahydroborate; ethanol at 0 - 20℃; for 4h; | 97.9% |
lamivudine
Conditions | Yield |
---|---|
With potassium carbonate In methanol at 0℃; for 10h; | 95% |
lamivudine
Conditions | Yield |
---|---|
Stage #1: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-[2-oxo-4-(phenylcarboxamido)-1,2-dihydro-1-pyrimidinyl]-1,3-oxathiolane-2-carboxylate With methanol at 40℃; Inert atmosphere; Stage #2: With sodium tetrahydroborate; dipotassium hydrogenphosphate; water; sodium hydroxide In methanol at 20℃; for 1h; diastereoselective reaction; | 95% |
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathialane-2-carbaxylate
lamivudine
Conditions | Yield |
---|---|
With lithium aluminium tetrahydride In tetrahydrofuran for 0.5h; Ambient temperature; | 94% |
With methanol; sodium tetrahydroborate; dipotassium hydrogenphosphate; sodium hydroxide In water at 20℃; for 0.055h; Flow reactor; | 94% |
With sodium tetrahydroborate In ethanol | 83% |
lamivudine salicyclic acid salt
lamivudine
Conditions | Yield |
---|---|
With triethylamine In ethanol at 50℃; for 1h; | 92.63% |
With triethylamine In water; ethyl acetate at 25 - 50℃; for 5h; Product distribution / selectivity; | |
With triethylamine In water; ethyl acetate at 45 - 50℃; for 4.5h; |
lamivudine
Conditions | Yield |
---|---|
Stage #1: 4-amino-1-[(2R,5S)-(2-hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one (S)-BINOL co-crystal With hydrogenchloride In water; ethyl acetate at 20℃; for 1h; pH=3 - 4; Stage #2: With sodium hydroxide In water pH=~ 7; Product distribution / selectivity; | 90% |
With hydrogenchloride In water; ethyl acetate pH=2 - 3; Large scale reaction; optical yield given as %ee; | 70.02% |
With hydrogenchloride In water; ethyl acetate pH=2 - 2.5; | |
Stage #1: 4-amino-1-[(2R,5S)-(2-hydroxymethyl)-1,3-oxathiolan-5-yl]-1,2-dihydropyrimidin-2-one (S)-BINOL co-crystal With hydrogenchloride In water; ethyl acetate at 20℃; for 0.0833333h; pH=3 - 4; Stage #2: With sodium hydroxide In water pH=6.8 - 7.2; Reagent/catalyst; | 7 g |
In water; ethyl acetate at 2 - 45℃; Industrial scale; | 33.3 kg |
lamivudine
Conditions | Yield |
---|---|
With triethylamine In ethanol at 70 - 75℃; Inert atmosphere; Industry scale; | 90% |
lamivudine
Conditions | Yield |
---|---|
With potassium carbonate In methanol at 20℃; for 14h; Inert atmosphere; | 89% |
lamivudine
Conditions | Yield |
---|---|
With triethylamine In Isopropyl acetate; water at 23 - 27℃; for 10h; Product distribution / selectivity; | 88% |
(2R,5S)-5-(4"-amino-2"-oxo-pyrimidin-1"-yl)-1,3-oxathiolane-2-methyl-(2'S-isopropyl-5'R-methyl-1'R-cyclohexyl)-carbonic acid diester
lamivudine
Conditions | Yield |
---|---|
With potassium carbonate In methanol at 0 - 25℃; for 3h; | 87.17% |
With potassium carbonate In methanol at 0 - 25℃; for 2h; | 86% |
(2R,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>cytosine
lamivudine
Conditions | Yield |
---|---|
With tetrabutyl ammonium fluoride In tetrahydrofuran for 0.5h; Ambient temperature; | 75% |
With tetrabutyl ammonium fluoride In tetrahydrofuran Ambient temperature; | 75% |
(+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
lamivudine
Conditions | Yield |
---|---|
Stage #1: (+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine With (S)-N-acetyl-2-phenylglycine In methanol; acetone at -30 - 0℃; for 48h; Stage #2: With sodium hydroxide In dichloromethane; water for 0.5h; Product distribution / selectivity; | 32% |
Stage #1: (+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine With (S)-N-acetyl-2-phenylglycine In methanol; acetone at -30 - 0℃; for 48h; Resolution of racemate; Stage #2: With sodium hydroxide In dichloromethane; water for 0.5h; Purification / work up; | 32% |
Multi-step reaction with 3 steps 1: 95 percent / dimethylformamide / 20 °C 2: 50.6 percent / pyridine / acetonitrile / 48 h / 0 °C 3: 95 percent / K2CO3 / methanol / 10 h / 0 °C View Scheme |
Benzoic acid (2R,5S)-5-(4-amino-2-oxo-2H-pyrimidin-1-yl)-[1,3]oxathiolan-2-ylmethyl ester
lamivudine
Conditions | Yield |
---|---|
With Amberlite IRA400(OH) In ethanol Heating; |
B
lamivudine
C
(+)-(2R,5R)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
Conditions | Yield |
---|---|
With Amberlit IRA400 In methanol Heating; Yield given. Yields of byproduct given; | |
With Amberlit IRA400 In methanol Heating; Yield given. Yields of byproduct given. Title compound not separated from byproducts; |
B
lamivudine
Conditions | Yield |
---|---|
With ammonia In methanol Yield given. Title compound not separated from byproducts; |
lamivudine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 50.6 percent / pyridine / acetonitrile / 48 h / 0 °C 2: 95 percent / K2CO3 / methanol / 10 h / 0 °C View Scheme |
(2R,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>-N4-acetylcytosine
lamivudine
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 73 percent / methanolic NH3 / 3 h / Ambient temperature 2: 75 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 0.5 h / Ambient temperature View Scheme | |
Multi-step reaction with 2 steps 1: 73 percent / NH3 / methanol / Ambient temperature 2: 75 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / Ambient temperature View Scheme |
(+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
B
lamivudine
Conditions | Yield |
---|---|
Stage #1: (+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine With (S)-N-acetyl-2-phenylglycine In ethanol at -30 - -20℃; for 48h; Stage #2: With sodium hydroxide In dichloromethane; water for 0.5h; Product distribution / selectivity; | A n/a B n/a |
Stage #1: (+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine With O,O'-dibenzoyl-L-tartaric acid In methanol; acetone at -30 - 20℃; for 48h; Stage #2: With sodium hydroxide In dichloromethane; water for 0.5h; Product distribution / selectivity; | A n/a B n/a |
Stage #1: (+/-)-cis-N-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine With (S)-N-acetyl-2-phenylglycine In methanol; acetone at -50 - 25℃; for 48h; Stage #2: With sodium hydroxide In dichloromethane; water for 0.5h; Product distribution / selectivity; | A n/a B n/a |
(1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathialane-2-carbaxylate
salicylic acid
lamivudine
Conditions | Yield |
---|---|
Stage #1: (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2R,5S)-5-(4-amino-2-oxo-1,2-dihydro-1-pyrimidinyl)-1,3-oxathiolane-2-carboxylate With sodium tetrahydroborate; dipotassium hydrogenphosphate In ethanol; water at 18 - 22℃; for 8 - 9h; Stage #2: salicylic acid In water at 10 - 82℃; |
A
lamivudine
B
(+)-(2R,5R)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
Conditions | Yield |
---|---|
With methanol; potassium carbonate at 20℃; |
A
lamivudine
B
(+)-(2R,5R)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
Conditions | Yield |
---|---|
With methanol; potassium carbonate at 20℃; |
A
lamivudine
B
(+)-(2R,5R)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
Conditions | Yield |
---|---|
With methanol; potassium carbonate at 20℃; |
(2R,5S)-5-(4'-acetamido-2'-oxo-pyrimidin-1'-yl)-1,3-oxathiolane-2-methyl-(4'-chloro)-benzoate
A
lamivudine
B
(+)-(2R,5R)-1-<2-(hydroxymethyl)-1,3-oxathiolan-5-yl>cytosine
Conditions | Yield |
---|---|
With methanol; potassium carbonate at 20℃; |
lamivudine
Conditions | Yield |
---|---|
Stage #1: (2R-cis)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone S-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate With hydrogenchloride In ethanol; water at 20 - 50℃; Stage #2: With sodium hydroxide In ethanol; water at 5 - 50℃; pH=7.5; Product distribution / selectivity; | n/a |
(S)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate
lamivudine
Conditions | Yield |
---|---|
Stage #1: cis-(+/-)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone; (S)-1,1'-binaphthyl-2,2'-diyl hydrogen phosphate With sodium hydroxide In water at 20 - 45℃; Stage #2: With hydrogenchloride In ethanol; water at 20℃; Stage #3: With sodium hydroxide In ethanol; water at 5 - 50℃; pH=7.5; Product distribution / selectivity; | n/a |
lamivudine
Conditions | Yield |
---|---|
With triethylamine In water; ethyl acetate at 22 - 30℃; for 4.5h; | |
With triethylamine In ethanol; water at 18 - 80℃; | |
With triethylamine In water; ethyl acetate at 22 - 30℃; for 4.5h; Product distribution / selectivity; |
lamivudine
Conditions | Yield |
---|---|
With triethylamine In methanol; water at 22 - 30℃; for 4.5h; Product distribution / selectivity; | |
With triethylamine In ethanol; ethyl acetate at 47 - 80℃; Product distribution / selectivity; |
lamivudine
Conditions | Yield |
---|---|
With pyridine; tetraphosphorus decasulfide at 22 - 42℃; for 10h; Inert atmosphere; | |
With pyridine; tetraphosphorus decasulfide at 22 - 42℃; for 10h; Inert atmosphere; |
benzoic acid anhydride
lamivudine
Conditions | Yield |
---|---|
In N,N-dimethyl-formamide at 20℃; for 24h; | 98% |
In ethanol at 70℃; for 2.5h; Sealed tube; | 80% |
lamivudine
Conditions | Yield |
---|---|
Stage #1: lamivudine With diphenyl hydrogen phosphite In pyridine at 20℃; for 0.5h; Stage #2: With triethylamine In water | 95% |
Conditions | Yield |
---|---|
With pyridine at 20℃; for 24h; | 95% |
tert-butyldimethylsilyl chloride
lamivudine
(-)-5'-O-(t-butyldimethylsilyl)-2',3'-dideoxy-3'-thiacytidine
Conditions | Yield |
---|---|
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; for 18h; | 95% |
With 1H-imidazole In N,N-dimethyl-formamide at 20℃; |
lamivudine
triethylamine
Conditions | Yield |
---|---|
Stage #1: lamivudine With diphenyl hydrogen phosphite In pyridine for 0.5h; Stage #2: triethylamine With water In pyridine | 93% |
lamivudine
tert-butylchlorodiphenylsilane
(2R,5S)-1-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-oxathiolan-5-yl>cytosine
Conditions | Yield |
---|---|
With 1H-imidazole In dichloromethane at 20℃; for 3h; Substitution; | 90% |
lamivudine
Conditions | Yield |
---|---|
With sodium (¹²⁵I)iodide; 1,3,4,6-tetrachloro-3α,6α-diphenyl glycoluril In aq. buffer at 60℃; for 0.166667h; pH=7; | 89% |
lamivudine
Conditions | Yield |
---|---|
With dmap; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 20℃; for 16h; | 88% |
cis-[RuCl2(triphenylphosphine)2(2,2′-bipyridine)]
lamivudine
Conditions | Yield |
---|---|
With triethylamine In methanol; dichloromethane for 24h; Reflux; Inert atmosphere; | 85% |
acetic anhydride
lamivudine
4-acetylamino-1-[(2'R,5'S)-2'-(hydroxymethyl)-1,3-oxathiolan-5'-yl]-1,2-dihydropyrimidin-2-one
Conditions | Yield |
---|---|
Stage #1: lamivudine In N,N-dimethyl-formamide at 20℃; for 0.0833333h; Inert atmosphere; Stage #2: acetic anhydride In N,N-dimethyl-formamide at 20℃; Inert atmosphere; | 82% |
Conditions | Yield |
---|---|
Stage #1: lamivudine With potassium hexamethylsilazane In tetrahydrofuran; N,N-dimethyl-formamide at 25℃; for 0.166667h; Inert atmosphere; Schlenk technique; Stage #2: 4-cyano-N,N,N-trimethylanilinium trifluoromethansulfonate In tetrahydrofuran; N,N-dimethyl-formamide at 25℃; for 3h; Inert atmosphere; Schlenk technique; | 82% |
Conditions | Yield |
---|---|
With benzotriazol-1-ol; dicyclohexyl-carbodiimide In dichloromethane; N,N-dimethyl-formamide at 60℃; for 7h; solid phase reaction; | 80% |
lamivudine
Conditions | Yield |
---|---|
With caesium carbonate In N,N-dimethyl-formamide at 20℃; for 3h; Inert atmosphere; Schlenk technique; | 75% |
Conditions | Yield |
---|---|
With pyridine; dicyclohexyl-carbodiimide | 73% |
Conditions | Yield |
---|---|
With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride In N,N-dimethyl-formamide at 0℃; for 3h; | 70% |
lamivudine
(2-(2-methoxyethoxy)ethyl) (4-nitrophenyl) carbonate
C14H21N3O7S
Conditions | Yield |
---|---|
With 1-hydroxy-pyrrolidine-2,5-dione In N,N-dimethyl-formamide at 20℃; for 72h; | 63% |
Conditions | Yield |
---|---|
Stage #1: Octanoic acid With 4-methyl-morpholine; 2-chloro-4,6-dimethoxy-1 ,3,5-triazine In dichloromethane; N,N-dimethyl-formamide at 10℃; for 1h; Stage #2: lamivudine In dichloromethane; N,N-dimethyl-formamide for 20h; | 56% |
lamivudine
12-azidododecanoyl chloride
(-)-N(4)-5'-di(12-azidododecanoyl)-2',3'-dideoxy-3'-thiacytidine
Conditions | Yield |
---|---|
With dmap In benzene at 100℃; for 4h; | 55% |
lamivudine
methyl iodide
Conditions | Yield |
---|---|
Stage #1: lamivudine With sodium hydride In tetrahydrofuran at 20℃; for 0.166667h; Inert atmosphere; Stage #2: methyl iodide In tetrahydrofuran at 20℃; Inert atmosphere; | 55% |
About|Contact|Cas|Product Name|Molecular|Country|Encyclopedia
Message|New Cas|MSDS|Service|Advertisement|CAS DataBase|Article Data|Manufacturers | Chemical Catalog
©2008 LookChem.com,License: ICP
NO.:Zhejiang16009103
complaints:service@lookchem.com Desktop View