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Lamivudine Basic information

New antiviral drug Methods of production What kind of patients suitable for use Lamivudine Zidovudine Pharmacokinetics drug withdrawal Adverse reactions and side effects Disabling condition Chemical property Uses

Product Name: Lamivudine

Synonyms: LaMivudine(Epivir);4-AMino-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;LaMivudine-13C-d2;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;cis-Lamivudine;(-)-BCH-189

CAS: 134678-17-4

MF: C8H11N3O3S

MW: 229.26

EINECS: 603-844-3

Product Categories: API's;HIV/AIDS/Related Products;Active Pharmaceutical Ingredients;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Intermediates & Fine Chemicals;Pharmaceuticals;API;DENDRID;Piperazines;Sulfur & Selenium Compounds

Mol File: 134678-17-4.mol

Lamivudine Structure

Lamivudine Chemical Properties

Melting point 177 °C

alpha D21 -135° (c = 0.38 in methanol)

Boiling point 475.4±55.0 °C(Predicted)

density 1.73±0.1 g/cm3(Predicted)

refractive index -142 ° (C=1, MeOH)

Fp 9℃

storage temp. Freezer

solubility water: soluble10mg/mL, clear

pka 13.83±0.10(Predicted)

form powder

color white to beige

Water Solubility 70g/L(temperature not stated)

Merck 14,5352

InChIKey JTEGQNOMFQHVDC-NKWVEPMBSA-N

CAS DataBase Reference 134678-17-4(CAS DataBase Reference)

EPA Substance Registry System 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]- (134678-17-4)