Lamivudine 4-Amino-1-[(2R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2-pyrimidinone (2R cis)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl])-(1H)pyrimidin-2-one
Lamivudine Basic information
New antiviral drug Methods of production What kind of patients suitable for use Lamivudine Zidovudine Pharmacokinetics drug withdrawal Adverse reactions and side effects Disabling condition Chemical property Uses
Product Name: Lamivudine
Synonyms: LaMivudine(Epivir);4-AMino-1-[(2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyriMidinone;3TC (-)-1-[(2R,5S)-2-(Hydroxymethyl)-1,3-oxathiolan-5-yl]cytosine;LaMivudine-13C-d2;3TC/Epivir-HBV;4-AMino-1-((2R,5S)-2-(hydroxyMethyl)-1,3-oxathiolan-5-yl)pyriMidin-2(1H)-one;cis-Lamivudine;(-)-BCH-189
CAS: 134678-17-4
MF: C8H11N3O3S
MW: 229.26
EINECS: 603-844-3
Product Categories: API's;HIV/AIDS/Related Products;Active Pharmaceutical Ingredients;Antivirals for Research and Experimental Use;Biochemistry;Chemical Reagents for Pharmacology Research;Nucleosides and their analogs;Nucleosides, Nucleotides & Related Reagents;Anti-virals;Intermediates & Fine Chemicals;Pharmaceuticals;API;DENDRID;Piperazines;Sulfur & Selenium Compounds
Mol File: 134678-17-4.mol
Lamivudine Structure
Lamivudine Chemical Properties
Melting point 177 °C
alpha D21 -135° (c = 0.38 in methanol)
Boiling point 475.4±55.0 °C(Predicted)
density 1.73±0.1 g/cm3(Predicted)
refractive index -142 ° (C=1, MeOH)
Fp 9℃
storage temp. Freezer
solubility water: soluble10mg/mL, clear
pka 13.83±0.10(Predicted)
form powder
color white to beige
Water Solubility 70g/L(temperature not stated)
Merck 14,5352
InChIKey JTEGQNOMFQHVDC-NKWVEPMBSA-N
CAS DataBase Reference 134678-17-4(CAS DataBase Reference)
EPA Substance Registry System 2(1H)-Pyrimidinone, 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]- (134678-17-4)
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