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Dayang Chem (Hangzhou) Co.,Ltd.

DayangChem exported this product to many countries and regions at best price. If you are looking for the material's manufacturer or supplier in China, DayangChem is your best choice. Pls contact with us freely for getting detailed product spe

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine Manufacturer/High quality/Best price/In stock

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality 2,9-Diacetylacyclovir supplier in China

Cas:75128-73-3

Min.Order:0 Metric Ton

Negotiable

Type:Manufacturers

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO

9-[(2-Acetoxyethoxy)Methyl]-N2-Acetylguanine manufacturer/supplier

Cas:75128-73-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:Yellow or light yellow crystalline powder Storage:cool dry place Package:25kg/drum Application:pharmaceutical inte

Manufacturer high quality Diacetyl Acyclovir Cas 75128-73-3 with good price

Cas:75128-73-3

Min.Order:1 Kilogram

Negotiable

Type:Trading Company

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Enke Pharma-tech Co.,Ltd. (Cangzhou, China )

Cangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new ap

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $1.0

Type:Manufacturers

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Chemwill Asia Co., Ltd.

Our main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block

9-[(2-Acetoxyethoxy)-methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:5 Kiloliter

FOB Price: $1.2 / 5.0

Type:Manufacturers

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LIDE PHARMACEUTICALS LIMITED

LIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $0.9 / 1.0

Type:Lab/Research institutions

inquiry

Hebei Nengqian Chemical Import and Export Co., LTD

With our good experience, we offer detailed technical support and advice to assist customers. We communicate closely with customers to establish their quality requirements. Consistent Quality Our plant has strict quality control in each manufacturin

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Pharmaceutical Grade CAS 75128-73-3 with competitive price

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

Acetamide,N-[9-[[2-(acetyloxy)ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]- 75128-73-3

Cas:75128-73-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Qingdao Beluga Import and Export Co., LTD

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine CAS:75128-73-3 Qingdao Belugas Import and Export Co., Ltd. is a scientific and technological company integrating research and development, production and trade of chemical intermediates, specializing in h

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine CAS:75128-73-3

Cas:75128-73-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai

Acetamide,N-[9-[[2-(acetyloxy)ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-

Cas:75128-73-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

Acetamide,N-[9-[[2-(acetyloxy)ethoxy]methyl]-6,9-dihydro-6-oxo-1H-purin-2-yl]-

Cas:75128-73-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Hisunny Chemical Co.,Ltd

Best quality & Attractive price & Professional service; Trial & Pilot & Commercial Hisunny Chemical is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality intermediates, specia

2,9-Diacetylacyclovir

Cas:75128-73-3

Min.Order:0

Negotiable

Type:Manufacturers

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Triumph International Development Limilted

Appearance:off-white to white solid Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for Synthesis API and Research Transportation:By Sea/Air/Courier Port:Qingdao

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine 75128-73-3

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $16.0 / 20.0

Type:Lab/Research institutions

inquiry

Wuhan Han Sheng New Material Technology Co.,Ltd

Our Advantage: high quality with competitive price High quality standard: BP/USP/EP Enterprise standard All purity customized Fast and safe delivery We have reliable forwarder who can help us deliver our goods more fast and safe. We

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:10 Kilogram

Negotiable

Type:Trading Company

inquiry

Taizhou Crene Biotechnology co.ltd

Our company provides one-stop services of research - development - production for a variety of special prouducts. Not only do we make effective use of our strong technological strength, but also establish of cooperative relations with several well-

Acyclovir EP Impurity G

Cas:75128-73-3

Min.Order:100 Gram

Negotiable

Type:Lab/Research institutions

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Hangzhou Keyingchem Co.,Ltd

Hangzhou KeyingChem Co., Ltd. exported this product to many countries and regions at best price. If you are looking for the material’s manufacturer or supplier in China, KeyingChem is your best choice. Pls contact with us freely for getting det

9-[(2-Acetoxyethoxy)Methyl]-N2-Acetylguanine

Cas:75128-73-3

Min.Order:0 Metric Ton

Negotiable

Type:Lab/Research institutions

inquiry

Afine Chemicals Limited

Company Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments

9-[(2-ACETOXYETHOXY)METHYL]-N2-ACETYLGUANINE;DIACETYL ACYCLOVIR

Cas:75128-73-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Hangzhou J&H Chemical Co., Ltd.

J&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Chemlyte Solutions

Chemlyte Solutions believe that customers and suppliers deserve much more than what traditional distributors can offer. To grow in today s fast-paced and increasingly competitive market it is essential to be able to quickly adapt to market forces eff

Featured products 9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:100 Gram

Negotiable

Type:Other

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Zibo Hangyu Biotechnology Development Co., Ltd

Zibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi

High quality 2,9-Diacetylacyclovir

Cas:75128-73-3

Min.Order:10 Gram

FOB Price: $100.0

Type:Lab/Research institutions

inquiry

SHANGHAI SYSTEAM BIOCHEM CO., LTD

We are one of a few suppliers that can offer custom synthesis service of this product We are specialized in custom synthesis, chemical/pharmaceutical/ pesticides outsourcing and contract research. We are committed to prov

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:100 Gram

FOB Price: $100.0 / 2000.0

Type:Lab/Research institutions

inquiry

HANGZHOU YUNUO CHEMICAL CO.,LTD

Superior quality, moderate price & quick delivery. Appearance:white to light yellow crystal powder Storage: Keep dry, stable at room temperature Package:25kg/drum, or as per your request. Application:Used as Pharmaceutical Intermediates

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine.

Cas:75128-73-3

Min.Order:1 Gram

Negotiable

Type:Trading Company

inquiry

Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate. In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so o

TIANFU CHEM 9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Wuhan Circle Star Chem-medical Technology co.,Ltd.

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualified

Factory Supply 9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine Supplier Manufacturer With Competitive Price

Cas:75128-73-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Zibo Dorne chemical technology co. LTD

Product Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine Manufacturer/High quality/Best price/In stock

Cas:75128-73-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

Xiamen Jenny Chemical Technology Co., Ltd.

GMP standard, high purity, competitive price, in stock 1. Quick Response: within 6 hours after receiving your email. 2. Quality Guarantee: All products are strictly tested by our QC, confirmed by QA, and approved by a third-party lab in China, USA,

9-[(2-Acetoxyethoxy)methyl]-N2-acetylguanine

Cas:75128-73-3

Min.Order:1 Milligram

Negotiable

Type:Trading Company

inquiry

EAST CHEMSOURCES LIMITED

factory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B

9-[(2-Acetoxyethoxy)methyl]-acetylguanine

Cas:75128-73-3

Min.Order:1 Kilogram

FOB Price: $18.0 / 20.0

Type:Trading Company

inquiry

Synthetic route

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

2,9-diacetylguanine
3056-33-5

2,9-diacetylguanine

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
at 105℃; for 80h;95.1%
With toluene-4-sulfonic acid In toluene at 110℃; Temperature; Large scale;94.3%
diacetyl guanine

diacetyl guanine

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
In methanol; dichloromethane94%
diacetylguanine

diacetylguanine

diacetyl guanine

diacetyl guanine

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
In methanol; toluene91%
2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

acetic anhydride
108-24-7

acetic anhydride

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 100℃; for 20h;A 86%
B 0.5%
With sulfuric acid at 100℃; for 24h; Product distribution; other acid caclysts, temperature time, solvents; transpurination reaction of guanosine under various conditions;A 43%
B 35%
With phosphoric acid at 100℃; for 24h; Title compound not separated from byproducts;A 47 % Chromat.
B 38 % Chromat.
acycloguanosine
59277-89-3

acycloguanosine

acetic anhydride
108-24-7

acetic anhydride

A

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

B

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
With dmap In N,N-dimethyl-formamide Acetylation;A 84%
B 4%
9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine
160053-81-6

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine

A

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

B

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine
120356-09-4

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine

C

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
With palladium diacetate; 1,3-bis-(diphenylphosphino)propane; triethylammonium formate In 1,4-dioxane at 90℃; for 0.5h;A 0.3%
B 80.4%
C 19.3%
9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
With dmap In hexane; acetic anhydride; toluene79%
acycloguanosine
59277-89-3

acycloguanosine

acetic anhydride
108-24-7

acetic anhydride

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
With pyridine for 1h; Heating;75%
2-hydroxyethyl acetate
542-59-6

2-hydroxyethyl acetate

N9-methyl-N2-acetylguanine

N9-methyl-N2-acetylguanine

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
With bis(tertbutylcarbonyloxy)iodobenzene; palladium diacetate In toluene at 90℃; for 24h;70%
N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide
19962-37-9

N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

1,1,1,3,3,3-hexamethyl-disilazane
999-97-3

1,1,1,3,3,3-hexamethyl-disilazane

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
Stage #1: N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide; 1,1,1,3,3,3-hexamethyl-disilazane With ammonium sulfate for 2h; Heating;
Stage #2: 2-acetoxyethyl acetoxymethyl ether; iodine-doped natural phosphate In acetonitrile Heating; Further stages.;
34%
Stage #1: N-(6-oxo-6,9-dihydro-1H-purin-2-yl)acetamide; 1,1,1,3,3,3-hexamethyl-disilazane With ammonium sulfate Heating;
Stage #2: 2-acetoxyethyl acetoxymethyl ether; natural phosphate; zinc dibromide In acetonitrile for 2h; Heating;
10%
1,3-DIOXOLANE
646-06-0

1,3-DIOXOLANE

acetic anhydride
108-24-7

acetic anhydride

2,9-diacetylguanine
3056-33-5

2,9-diacetylguanine

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid; acetic acid In toluene at 120℃; for 2.5h;A 29%
B 29%
2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

toluene-4-sulfonic acid
104-15-4

toluene-4-sulfonic acid

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7,9-bis[(2-acetoxyethoxy)methyl]-N2-acetylguanine

7,9-bis[(2-acetoxyethoxy)methyl]-N2-acetylguanine

Conditions
ConditionsYield
In chlorobenzene at 130℃; Substitution;A 28%
B 8%
Acetic acid 2-(2-oxo-propoxy)-ethyl ester
102728-65-4

Acetic acid 2-(2-oxo-propoxy)-ethyl ester

2,9-diacetylguanine
3056-33-5

2,9-diacetylguanine

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid 1.) 120-125 deg C, 2.) 150 deg C, 45 min;A 27%
B 22%
2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With acetic anhydride; toluene-4-sulfonic acid at 100℃; for 20h;A 22%
B 20%
1,3-DIOXOLANE
646-06-0

1,3-DIOXOLANE

2,9-diacetylguanine
3056-33-5

2,9-diacetylguanine

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With acetic anhydride; toluene-4-sulfonic acid In acetic acid for 1h; Heating;A 18%
B 2.3%
2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

acetic anhydride
108-24-7

acetic anhydride

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid 1.) acetic acid, 140 deg C, 18 h, 2.) DMSO, 100 deg C, 16 h; Yield given. Multistep reaction. Yields of byproduct given;
2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

acetic anhydride
108-24-7

acetic anhydride

2,9-diacetylguanine
3056-33-5

2,9-diacetylguanine

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid 1.) AcOH, 2.) toluene, reflux, 16 h; Yield given. Multistep reaction. Yields of byproduct given;
9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-toluenesulfonyloxy)-9H-purine
160053-80-5

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-toluenesulfonyloxy)-9H-purine

A

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

B

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine
120356-09-4

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine

C

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

D

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

Conditions
ConditionsYield
With hydrogen; Lindlar's catalyst In ethanol at 70℃; for 24h; Further byproducts given;A 6.6 % Chromat.
B 87.3 % Chromat.
C 1.0 % Chromat.
D 4.7 % Chromat.
9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine
160053-81-6

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine

A

9-<(2-acetoxyethoxy)methyl>-2-amino-9H-purine
92924-35-1

9-<(2-acetoxyethoxy)methyl>-2-amino-9H-purine

B

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

C

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one
110104-37-5

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one

D

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine
120356-09-4

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine

E

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

F

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethanol at 70℃; for 1h; Product distribution; other reagents;A 6.0 % Chromat.
B 1.2 % Chromat.
C 0.8 % Chromat.
D 74.7 % Chromat.
E 12.3 % Chromat.
F 4.7 % Chromat.
9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine
160053-81-6

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine

A

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one
110104-37-5

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one

B

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine
120356-09-4

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine

C

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

D

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

Conditions
ConditionsYield
With palladium diacetate; triethylammonium formate; triphenylphosphine In 1,4-dioxane at 90℃; for 1h; Further byproducts given;A 3.0 % Chromat.
B 57.6 % Chromat.
C 18.2 % Chromat.
D 20.8 % Chromat.
9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(2,4,6-trimethylbenzenesulfonyloxy)-9H-purine
160053-79-2

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(2,4,6-trimethylbenzenesulfonyloxy)-9H-purine

A

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

B

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine
120356-09-4

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-9H-purine

C

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

D

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-9H-purine

Conditions
ConditionsYield
With hydrogen; Lindlar's catalyst In ethanol at 70℃; for 24h; Further byproducts given;A 2.2 % Chromat.
B 91.8 % Chromat.
C 1.1 % Chromat.
D 4.5 % Chromat.
Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester
30747-23-0

Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid at 100℃; for 48h;A 42 % Chromat.
B 30 % Chromat.
7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
at 90 - 100℃; under 30 Torr; for 22.5h;
Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester
30747-23-0

Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

A

7-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-N2-acetylguanine
30747-22-9

7-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-N2-acetylguanine

B

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

C

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
In chlorobenzene; acetonitrile at 120℃; for 2h; Mechanism;
With toluene-4-sulfonic acid In chlorobenzene; acetonitrile at 120℃; for 2h;
7-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-N2-acetylguanine
30747-22-9

7-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)-N2-acetylguanine

2-acetoxyethyl acetoxymethyl ether
59278-00-1

2-acetoxyethyl acetoxymethyl ether

A

Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester
30747-23-0

Acetic acid (2R,3R,4R,5R)-4-acetoxy-5-acetoxymethyl-2-(2-acetylamino-6-oxo-1,6-dihydro-purin-9-yl)-tetrahydro-furan-3-yl ester

B

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

C

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
With toluene-4-sulfonic acid In chlorobenzene; acetonitrile at 120℃; for 2h;
7,9-bis[(2-acetoxyethoxy)methyl]-N2-acetylguanine

7,9-bis[(2-acetoxyethoxy)methyl]-N2-acetylguanine

A

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

B

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine
91702-60-2

7-<(2-acetoxyethoxy)methyl>-N2-acetylguanine

Conditions
ConditionsYield
at 210℃; for 0.0833333h; Decomposition;
In chlorobenzene at 70℃; for 2h; Decomposition;
2-amino-1,9-dihydro-6H-purin-6-one
73-40-5

2-amino-1,9-dihydro-6H-purin-6-one

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1.1: triflic acid / 32 h / 160 °C
1.2: 93 percent / 12 h / Heating
2.1: 85 percent / acetic acid / H2O / 2 h / 80 °C
3.1: 75 percent / pyridine / 1 h / Heating
View Scheme
9-(2-trimethylsilyloxyethoxymethyl)guanine
364634-35-5

9-(2-trimethylsilyloxyethoxymethyl)guanine

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 85 percent / acetic acid / H2O / 2 h / 80 °C
2: 75 percent / pyridine / 1 h / Heating
View Scheme
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
With sodium hydroxide In water at 85 - 95℃; for 3h;97.5%
With methylamine In water at 23℃; for 1h;93%
With sodium hydroxide92%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

9-[(acetoxyethoxy)methyl]guanine
102728-64-3

9-[(acetoxyethoxy)methyl]guanine

Conditions
ConditionsYield
With triethylamine In ethanol for 10h; Heating;97%
With triethanolamine In methanol92%
With methanol; sodium methylate for 16h; Ambient temperature;81%
With Schwartz's reagent In tetrahydrofuran at 20℃; Inert atmosphere; chemoselective reaction;47%
Multi-step reaction with 2 steps
1: 81 percent / DMAP, Et3N / CH2Cl2 / 1 h / Ambient temperature
2: 2.2 percent Chromat. / hydrogen / Pd/CaCO3 / ethanol / 24 h / 70 °C
View Scheme
2,4,6-triisopropylphenylsulfonyl chloride
6553-96-4

2,4,6-triisopropylphenylsulfonyl chloride

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(2,4,6-triisopropylbenzenesulfonyloxy)-9H-purine
160053-78-1

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(2,4,6-triisopropylbenzenesulfonyloxy)-9H-purine

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane Ambient temperature;95%
ammonium hydroxide
1336-21-6

ammonium hydroxide

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

acycloguanosine
59277-89-3

acycloguanosine

Conditions
ConditionsYield
In methanol90%
2-mesitylenesulphonyl chloride
773-64-8

2-mesitylenesulphonyl chloride

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(2,4,6-trimethylbenzenesulfonyloxy)-9H-purine
160053-79-2

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(2,4,6-trimethylbenzenesulfonyloxy)-9H-purine

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 1h; Ambient temperature;81%
potassium tetrachloroplatinate(II)
10025-99-7

potassium tetrachloroplatinate(II)

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

C24H30Cl2N10O10Pt
136686-48-1, 174173-25-2

C24H30Cl2N10O10Pt

Conditions
ConditionsYield
In water molar ratio K2PtCl4:ligand = 1:2, suspension stirred at room temp. for 3 d; washed with water, methanol, ether; elem. anal.;80%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

diphenylcarbamic chloride
83-01-2

diphenylcarbamic chloride

9-<(2-acetoxyethoxy)methyl>-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine
112233-78-0

9-<(2-acetoxyethoxy)methyl>-2-N-acetyl-6-O-(diphenylcarbamoyl)guanine

Conditions
ConditionsYield
With pyridine; N-ethyl-N,N-diisopropylamine at 20℃; for 4h;77%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

p-toluenesulfonyl chloride
98-59-9

p-toluenesulfonyl chloride

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-toluenesulfonyloxy)-9H-purine
160053-80-5

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-toluenesulfonyloxy)-9H-purine

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 10h; Ambient temperature;74%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

2-((2-acetamido-6-thioxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl acetate
92924-39-5

2-((2-acetamido-6-thioxo-1,6-dihydro-9H-purin-9-yl)methoxy)ethyl acetate

Conditions
ConditionsYield
With [p-CH3OC6H4P(S)S]2 In pyridine for 7h; Heating;74%
With diphosphorus pentasulfide In pyridine65%
4-Fluorobenzenesulfonyl chloride
349-88-2

4-Fluorobenzenesulfonyl chloride

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine
160053-81-6

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-(p-fluorobenzenesulfonyloxy)-9H-purine

Conditions
ConditionsYield
With dmap; triethylamine In dichloromethane for 24h; Ambient temperature;70%
potassium trichloro(ethene)platinate(II)
12012-50-9

potassium trichloro(ethene)platinate(II)

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

trans-{PtCl2(η(2)-C2H4)(9-(2-acetoxyethoxymethyl)-N(2)-acetylguanine)}
136686-43-6

trans-{PtCl2(η(2)-C2H4)(9-(2-acetoxyethoxymethyl)-N(2)-acetylguanine)}

Conditions
ConditionsYield
In methanol stoich. amt. of C12H15N5O5, 2 h of stirring at 0°C, evapn. of solvent in vac.; dissolved in the min. amt. of dichloromethane, filtered, solvent slowly evapd. in vac.; elem. anal.;70%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one
110104-37-5

2-acetylamino-9-<(2-hydroxyethoxy)methyl>-1,9-dihydro-6H-purin-6-one

Conditions
ConditionsYield
With sodium methylate In methanol at 23℃; for 0.266667h;67%
With methanol; sodium at 21℃; for 0.266667h;57%
With ammonium hydroxide at 50℃; for 1h;55%
cis-bis(dimethylsulfoxide)dichloroplatinum(II)
15274-33-6

cis-bis(dimethylsulfoxide)dichloroplatinum(II)

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

trans-(PtCl2(DMSO)(9-(2-acetoxyethoxymethyl)-N(2)-acetylguanine))
136686-46-9, 136778-46-6

trans-(PtCl2(DMSO)(9-(2-acetoxyethoxymethyl)-N(2)-acetylguanine))

cis-(PtCl2(DMSO)(9-(2-acetoxyethoxymethyl)-N(2)-acetylguanine))
136686-46-9, 136778-46-6

cis-(PtCl2(DMSO)(9-(2-acetoxyethoxymethyl)-N(2)-acetylguanine))

Conditions
ConditionsYield
In methanol stoich. amt., stirring for 1 day; redn. of vol., filtration, excess of diethyl ether, pptn.; elem. anal.;A 65%
B n/a
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

benzyl bromide
100-39-0

benzyl bromide

A

2-Acetamido-9-[(2-acetoxyethoxy)methyl]-6-benzyloxypurine

2-Acetamido-9-[(2-acetoxyethoxy)methyl]-6-benzyloxypurine

B

9-[(2-Acetoxyethoxy)methyl]-2-(N-benzylacetamido)-6-benzyloxypurine

9-[(2-Acetoxyethoxy)methyl]-2-(N-benzylacetamido)-6-benzyloxypurine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 100℃; for 16h; Alkylation;A 50%
B 13%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-chloro-9H-purine
120356-08-3

9-<(2-acetoxyethoxy)methyl>-2-acetylamino-6-chloro-9H-purine

Conditions
ConditionsYield
With 2,4,6-trimethyl-pyridine; tetraethylammonium chloride; trichlorophosphate In acetonitrile for 0.166667h; Heating;37%
With N,N-diethylaniline; trichlorophosphate In acetonitrile
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

methyl iodide
74-88-4

methyl iodide

A

9-[(2-Acetoxyethoxy)methyl]-6-methoxy-2-(N-methylacetamido)purine

9-[(2-Acetoxyethoxy)methyl]-6-methoxy-2-(N-methylacetamido)purine

B

2-Acetamido-9-[(2-acetoxyethoxy)methyl]-6-methoxypurine

2-Acetamido-9-[(2-acetoxyethoxy)methyl]-6-methoxypurine

C

9-[(2-Acetoxyethoxy)methyl]-1-methyl-2-(N-methylacetamido)-6-oxopurine

9-[(2-Acetoxyethoxy)methyl]-1-methyl-2-(N-methylacetamido)-6-oxopurine

Conditions
ConditionsYield
With potassium carbonate In N,N-dimethyl-formamide at 50℃; for 16h; Methylation;A 8%
B 4%
C 33%
2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one
75128-73-3

2-acetylamino-9-(2-acetoxyethoxymethyl)purine-6-one

Acetic acid 2-(2-acetylamino-8-fluoro-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

Acetic acid 2-(2-acetylamino-8-fluoro-6-oxo-1,6-dihydro-purin-9-ylmethoxy)-ethyl ester

Conditions
ConditionsYield
With fluorine In chloroform for 1h; Ambient temperature;30%
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