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ZHANGJIAGANG HUAMAO FINE CHEMICAL CO.,LTD

Zhangjiagang Huamao Fine Chemical Co., Ltd. was founded in 2006. It is a Sino-US joint venture engaged in research and production. The company is situated in Yangtze River International Chemical Industrial Park, Free Trade Zone, Zhangjiagang. Based o

L-tert-leucine

Cas:20859-02-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

inquiry

Zhejiang Haizhou Pharmaceutical Co., Ltd.

Specification: In-house Certifcation: ISO 9001; GMP Management; US FDA and China NMPA Approved Plant Appearance:White Storage:Preserve in ambient temperature Package:25kg/drum, full-paper drum Application:Used for Nirmatrelvir; Used for a key precu

L-tert-Leucine

Cas:20859-02-3

Min.Order:50 Gram

Negotiable

Type:Manufacturers

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Dayang Chem (Hangzhou) Co.,Ltd.

As a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch

L-tert-Leucine Manufacturer/High quality/Best price/In stock

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $3.0

Type:Lab/Research institutions

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Simagchem Corporation

Welcome to Simagchem, your partner in China as a premier supply of bulk specialty chemicals for industry and life science. We introduce experienced quality product and exceptional JIT service with instant market intelligence in China to benefit our

High quality L-Tert-Leucine supplier in China

Cas:20859-02-3

Min.Order:1 Kilogram

Negotiable

Type:Manufacturers

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Sinoway Industrial Co., Ltd.

Assay: 99% up; Produced by order Appearance:White crystalline powder Storage:room temprature Package:25kg/drum Application:intermediate of Atazanavir,Glecaprevir Port:Beijing/Shanghai/Shenzhen/Hangzhou

L-tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $180.0 / 200.0

Type:Trading Company

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Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need C

compound amino acid injection(18AA) 200ml/10g;250ml/12.5g;500ml/25g

Cas:20859-02-3

Min.Order:1 Gram

Negotiable

Type:Manufacturers

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Wuhan Fortuna Chemical Co.,Ltd

Unique advantages of L-tert-Leucine Cas 20859-02-3 Guaranteed purity High quality & competitive price Quality control Fast feedback Prompt shipment Appearance:White to off-white powder Storage:cool dry place Package:25kg/drum Application:L-t

Manufacturer high quality L-tert-Leucine Cas 20859-02-3 with good price

Cas:20859-02-3

Min.Order:25 Kilogram

Negotiable

Type:Trading Company

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Xi'an Quanao Biotech Co., Ltd.

Natural Sea Cucumber Extract Powder 99% Sea Cucumber Polypeptide Professional Factory We has a complete production and operating system, with an annual output capacity of 2000 tons. It can produce variety of content and proportion of extract accord

Natural Sea Cucumber Extract Powder 99% Sea Cucumber Polypeptide

Cas:20859-02-3

Min.Order:25 Kilogram

FOB Price: $140.0 / 150.0

Type:Manufacturers

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Ality Chemical Corporation

The above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi

Factory Supply L-Tert-Leucine

Cas:20859-02-3

Min.Order:1

Negotiable

Type:Other

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Xi'an Xszo Chem Co., Ltd.

1. Factory price and high quality must be guaranteed, base on 8 years of production and R&D experience2. Free samples will be provided,ensure specifications and quality are right for customer3. Customers will receive the most professional technical s

High Quality Food Grade L-Tert-Leucine 20859-02-3 HACCP Manufacturer

Cas:20859-02-3

Min.Order:1 Gram

FOB Price: $0.1

Type:Manufacturers

inquiry

Chemwill Asia Co., Ltd.

L-tert-Leucine CAS 20859-02-3 L-2-Amino-3,3-dimethylbutanoic acid CAS no 20859-02-3 L-tert-Leucine CAS 20859-02-3 L-(+)-tert-Leucine L-2-Amino-3,3-dimethylbutanoic acid L-2-AMINO-4-METHYLVALERIC ACID L-tert-Leucine CAS 20859-02-3 L-2-Ami

L-tert-Leucine CAS 20859-02-3 L-2-Amino-3,3-dimethylbutanoic acid CAS no 20859-02-3 L-(+)-tert-Leucine

Cas:20859-02-3

Min.Order:5 Kiloliter

FOB Price: $3.5 / 5.0

Type:Manufacturers

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GIHI CHEMICALS CO.,LIMITED

GIHI CHEMICALS exported this product to many countries and regions at best price. if you are looking for the material's manufacturer or supplier in china, GIHI CHEMICALS is your best choice. pls contact with us freely for getting detailed prod

L-tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $5.0

Type:Lab/Research institutions

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Hubei DiBo chemical co., LTD

Name:L-tert-Leucine CAS NO: 20859-02-3 Grade:Medical scientific research and export Molecular formula:C6H13NO2 Molecular weight:131.1729 Product Quality 12 years of chemical raw materials Mature operation of the industry System stability

L-tert-Leucine/cas:20859-02-3/Raw material spot

Cas:20859-02-3

Min.Order:25 Kilogram

FOB Price: $1.0 / 2.0

Type:Other

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Henan Tianfu Chemical Co., Ltd.

Our company was built in 2009 with an ISO certificate.In the past 6 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O

CAS 20859-02-3 L-tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $1000.0

Type:Lab/Research institutions

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Hebei Nengqian Chemical Import and Export Co., LTD

Our Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con

L-Tert-Leucine 98% CAS20859-02-3

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $1.0 / 10.0

Type:Trading Company

inquiry

Zhuozhou Wenxi import and Export Co., Ltd

WITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et

Factory direct supply CAS 20859-02-3 with best quality

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $139.0 / 210.0

Type:Trading Company

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Henan Sinotech Import&Export Corporation

English name: L-tert-Leucine CAS No.: 20859-02-3 Formula: C6H13NO2 Molecular Weight: 131.17 Synonyms: H-Tle-OH;L-tert-Leu-OH;L-tert·Leucine;L-Valine, 3-methyl-;L-tert Leucine;L-tert-Leucine(L-2-Amino-3,3-dimethylbutanoic acid);

L-2-Amino-3,3-dimethylbutanoic acid 20859-02-3

Cas:20859-02-3

Min.Order:5 Metric Ton

FOB Price: $1.0 / 2.0

Type:Other

inquiry

Shandong Hanjiang Chemical Co., Ltd.

Hello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by email in time prod

L-tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Langyou International Trading Co., Ltd

1. Guaranteed purity; 2. Large quantity in stock; 3. Largest manufacturer; 4. Best service after shipment with email; 5. High quality & competitive price; Appearance:White Crystalline Powder Storage:Store in sealed conta

high quality 20859-02-3 L-tert-Leucine with best price

Cas:20859-02-3

Min.Order:10 Gram

Negotiable

Type:Other

inquiry

Hangzhou Sartort Biopharma Co., Ltd

Appearance:White to almost white powder Storage:Room temperature Package:25kg/drum Application:Nutritional supplements Transportation:Express/Sea/Air Port:Any port in china

High Quality Factory Supply Telaprevir intermediate L-Tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Shanghai Upbio Tech Co.,Ltd

1.No Less 8 years exporting experience. Clients can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specialized

L-tert-Leucine 20859-02-3

Cas:20859-02-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Xi'an Faithful Biotech Co., Ltd.

We are the manufacturers and suppliers of API in China, and warehouse in Germany and USA of California, which can quickly and safely deliver to your address 1.High quality and competitive price. 2.Free sample for your evaluation. 3.Promptly delivery

Baoji Guokang Healthchem co.,ltd

Our company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At prese

L-tert-Leucine, 99%

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $136.0 / 150.0

Type:Trading Company

inquiry

Qingdao Beluga Import and Export Co., LTD

Beluga chemical professional supply High quality L-tert-Leucine CAS 20859-02-3 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and research capabilities. 2. Made in China

High quality L-tert-Leucine CAS 20859-02-3

Cas:20859-02-3

Min.Order:1 Gram

Negotiable

Type:Lab/Research institutions

inquiry

LIDE PHARMACEUTICALS LIMITED

Advantage : LIDE PHARMACEUTICALS LTD. is a mid-small manufacturing-type enterprise, engaged in pharmaceutical intermediates of R&D, custom-made and production, and also involving trading chemicals for export. We have established the R&amp

L-tert-Leucine/ LIDE PHARMA- Factory supply / Best price

Cas:20859-02-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hubei Jiutian Bio-medical Technology Co., Ltd

1,we produce and sell good chemicals around the world. 2,our success rate is about 95%. this means, if customer order is accepted, the probability that the customer will obtain the ordered substances, is 95%. 3,our staff consists of highly qualifie

CAS 20859-02-3 L-tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

Negotiable

Type:Lab/Research institutions

inquiry

Henan Wentao Chemical Product Co., Ltd.

Henan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod

CAS NO.:20859-02-3

Cas:20859-02-3

Min.Order:0

Negotiable

Type:Lab/Research institutions

inquiry

Hebei Mojin Biotechnology Co.,Ltd

Company information: Hebei Mojin Biotechnology Co., Ltd, Our company is a professional in chemical raw materials and chemical reagents research and development production enterprises. Our business covers more than 30 countries, most of the big custo

L-Tert-Leucine CAS 20859-02-3

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $8.0 / 10.0

Type:Trading Company

inquiry

Hebei Quanhe Biotechnology Co. LTD

1. Timely and efficient service to ensure communication with customers 2. Produce products of different specifications and sizes according to your requirements. 3. Quality procedures and standards recognized by SGS. Advanced plant equipment ensures s

L-tert-Leucine

Cas:20859-02-3

Min.Order:1 Kilogram

FOB Price: $40.0 / 60.0

Type:Lab/Research institutions

inquiry

Guangdong Juda Chemical Industrial Co.,Limited

1) For products exported we can offer COA Certificate and official PI. 2) We are manufacturer with own lab and factory, can provide high quality products with factory price. 3) Products can be sent out in 24 hours after payment. Tracking number avai

High Purity Powder L-Tert-Leucine CAS 20859-02-3 with Best Price

Cas:20859-02-3

Min.Order:100 Kilogram

Negotiable

Type:Trading Company

inquiry

Synthetic route

L-tert-leucine·3,4-dimethylbenzenesulfonate

L-tert-leucine·3,4-dimethylbenzenesulfonate

A

L-tert-Leucine
20859-02-3

L-tert-Leucine

B

3,4-dimethylbenzenesulfonic acid
618-01-9

3,4-dimethylbenzenesulfonic acid

Conditions
ConditionsYield
In water at 30 - 45℃; Product distribution / selectivity;A 96.5%
B 100%
3,3-dimethyl-2-oxobutanoate

3,3-dimethyl-2-oxobutanoate

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With glutamate at 37℃; for 0.5h; pH=8; Kinetics; Reagent/catalyst; aq. phosphate buffer; Enzymatic reaction; optical yield given as %ee;100%
(R)-2-amino-3,3-dimethyl-butyric acid amide
319930-78-4

(R)-2-amino-3,3-dimethyl-butyric acid amide

butan-1-ol
71-36-3

butan-1-ol

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
98%
N-tert-butyloxycarbonyl-L-tert-leucine
62965-35-9

N-tert-butyloxycarbonyl-L-tert-leucine

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride In 1,4-dioxane97%
Stage #1: N-tert-butyloxycarbonyl-L-tert-leucine With methanesulfonic acid In dichloromethane at 25℃; for 3h;
Stage #2: With triethylamine In dichloromethane at 25℃; for 1h;
75%
With hydrogenchloride In water; toluene at 60℃; for 3h;
(3S,5S)-3-tert-Butyl-5-phenyl-morpholin-2-one
202347-81-7

(3S,5S)-3-tert-Butyl-5-phenyl-morpholin-2-one

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogen; trifluoroacetic acid; palladium dihydroxide In methanol; water under 3750.3 Torr; for 24h;95%
3,3-dimethyl-2-oxobutanoate

3,3-dimethyl-2-oxobutanoate

rac-methylbenzylamine
618-36-0

rac-methylbenzylamine

A

L-tert-Leucine
20859-02-3

L-tert-Leucine

B

acetophenone
98-86-2

acetophenone

Conditions
ConditionsYield
With pyridoxal 5'-phosphate; (S)-selective ω-transaminase from Paracoccus denitrificans; branched-chain aminoacid transaminase; 2-aminobutanoic acid In aq. phosphate buffer; hexane for 61h; pH=7; Kinetics; Solvent; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;A 94%
B n/a
(R)-2-amino-3,3-dimethyl-butyric acid amide
319930-78-4

(R)-2-amino-3,3-dimethyl-butyric acid amide

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
92%
α-ureido-tert-leucine

α-ureido-tert-leucine

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride; sodium nitrite In water at 40℃; for 11.75h;90.6%
(S)-(+)-2-amino-3,3-dimethylbutanamide
62965-57-5

(S)-(+)-2-amino-3,3-dimethylbutanamide

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride at 100℃; for 24h;86%
With hydrogenchloride at 100℃;76%
trimethylpyruvic acid
815-17-8

trimethylpyruvic acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With ammonium hydroxide; D-glucose; ammonium chloride; sodium hydroxide In water for 5.5h; pH=8.3; Time; Reagent/catalyst; Enzymatic reaction; stereoselective reaction;80%
With L-ornithine; L-glutamic acid; Bacillus subtilis ornithine aminotransferase; Escherichia coli branched-chain amino acid aminotransferase; sodium hydroxide In aq. phosphate buffer at 37℃; for 16h; pH=8.5; Reagent/catalyst; Concentration; Time; Enzymatic reaction;73%
With L-valine; leucine dehydrogenase; pyridoxal 5'-phosphate; alcohol dehydrogenases from Bacillus stearothermophilus; branched-chain amino acid aminotransferase; NADH In isopropyl alcohol at 35℃; for 9h; pH=8; Reagent/catalyst; Enzymatic reaction; enantioselective reaction;68.7%
C14H21NO3

C14H21NO3

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With palladium 10% on activated carbon In methanol at 50℃; for 12h; Inert atmosphere;80%
(S)-2-<(R)-2-hydroxy-1-phenylethylamino>-3,3-dimethylbutanoic acid
145058-02-2

(S)-2-<(R)-2-hydroxy-1-phenylethylamino>-3,3-dimethylbutanoic acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With formic acid; palladium In methanol; water Ambient temperature;76%
(S)-2-benzoylamino-3,3-dimethylbutyric acid
162377-68-6

(S)-2-benzoylamino-3,3-dimethylbutyric acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride; Amberlite IRA-67 1.) propan-2-ol, 70 deg C, 15 h; 2.) water, 15 h;74%
With potassium hydroxide In methanol; water; acetone
L-tert-leucine tert-butylamide hydrochloride
126402-95-7

L-tert-leucine tert-butylamide hydrochloride

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride at 80℃; for 24h;70%
N-[(1R)-2,2-dimethyl-1-phenylpropyl]-2,2,2-trifluoroacetamide
528819-01-4

N-[(1R)-2,2-dimethyl-1-phenylpropyl]-2,2,2-trifluoroacetamide

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
Stage #1: N-[(1R)-2,2-dimethyl-1-phenylpropyl]-2,2,2-trifluoroacetamide With ruthenium trichloride; sodium periodate In tetrachloromethane; water; acetonitrile at 20℃; for 24h; Sharpless oxidation;
Stage #2: With sodium hydroxide In methanol at 20℃; for 16h;
68%
N-succinyl-DL-tert-leucine
1340309-12-7

N-succinyl-DL-tert-leucine

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
45%
CoCl2
(S)-2-amino-3,3-dimethylbutanamide hydrochloride

(S)-2-amino-3,3-dimethylbutanamide hydrochloride

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With sodium hydroxide; manganese(ll) chloride; leucine aminopeptidase In water at 37℃; for 40h;35%
(±)-2-amino-3,3-dimethylbutanamide
62965-57-5, 113582-42-6, 144177-62-8

(±)-2-amino-3,3-dimethylbutanamide

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
mit Hilfe eines Enzym-Praeparats aus Schweine-Nieren;
Multi-step reaction with 3 steps
1: chlorocarbonic acid benzyl ester
2: amidase-substance from pig's kidney
3: palladium; methanol; acetic acid / Hydrogenation
View Scheme
L-2-formylamino-3,3-dimethyl-butyric acid
92571-61-4

L-2-formylamino-3,3-dimethyl-butyric acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogen bromide
(S)-N-carbobenzoxy-tert-butylleucine
62965-10-0

(S)-N-carbobenzoxy-tert-butylleucine

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With methanol; palladium; acetic acid Hydrogenation;
(hydrogenolysis);
methyl tert-leucinate
3850-31-5

methyl tert-leucinate

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
(i) liq. NH3, (ii) (racemate resolution using D-tartaric acid), (iii) aq. HCl; Multistep reaction;
(S)-2-amino-3,3-dimethyl-butyric acid methyl ester
63038-26-6

(S)-2-amino-3,3-dimethyl-butyric acid methyl ester

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride
(S)-2-acetylamino-3,3-dimethylbutyric acid
22146-59-4

(S)-2-acetylamino-3,3-dimethylbutyric acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride In ethanol
(S)-2-[(S)-3,3-Dimethyl-2-(2,2,2-trifluoro-acetylamino)-butyrylamino]-pentanedioic acid dimethyl ester

(S)-2-[(S)-3,3-Dimethyl-2-(2,2,2-trifluoro-acetylamino)-butyrylamino]-pentanedioic acid dimethyl ester

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride
3,3-dimethyl-2-oxo-butanoic acid phenyhydrazone
38559-30-7

3,3-dimethyl-2-oxo-butanoic acid phenyhydrazone

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
hydrogenation; Yield given;
(S)-α-azido-3,3-dimethyl butanoic acid
111525-71-4

(S)-α-azido-3,3-dimethyl butanoic acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogen; palladium on activated charcoal In ethyl acetate under 760 Torr; for 13h; Yield given;
C10H22N2O*H(1+)

C10H22N2O*H(1+)

L-tert-Leucine
20859-02-3

L-tert-Leucine

Conditions
ConditionsYield
With hydrogenchloride; Amberlite IR-120 1.) 80 deg C; Yield given. Multistep reaction;
chloroacetyl-D,L-tert-leucine
121703-98-8

chloroacetyl-D,L-tert-leucine

A

L-tert-Leucine
20859-02-3

L-tert-Leucine

B

(R)-2-(2-Chloro-acetylamino)-3,3-dimethyl-butyric acid
121703-98-8

(R)-2-(2-Chloro-acetylamino)-3,3-dimethyl-butyric acid

Conditions
ConditionsYield
With potassium hydroxide; potassium phosphate buffer; porcine kidney acylase I at 40℃; relative initial rate of hydrolysis, also with Aspergillus acylase I as a catalyst; with or without CoCl2;
4-Methyl-benzenesulfinic acid (1-cyano-2,2-dimethyl-propyl)-amide

4-Methyl-benzenesulfinic acid (1-cyano-2,2-dimethyl-propyl)-amide

A

L-tert-Leucine
20859-02-3

L-tert-Leucine

B

D-tert-leucine
26782-71-8

D-tert-leucine

Conditions
ConditionsYield
With hydrogenchloride Yield given. Yields of byproduct given. Title compound not separated from byproducts;
(R)-3,3-Dimethyl-2-(2-oxo-4-phenyl-oxazolidin-3-yl)-butyric acid

(R)-3,3-Dimethyl-2-(2-oxo-4-phenyl-oxazolidin-3-yl)-butyric acid

A

L-tert-Leucine
20859-02-3

L-tert-Leucine

B

D-tert-leucine
26782-71-8

D-tert-leucine

Conditions
ConditionsYield
With ammonia; lithium In tetrahydrofuran; tert-butyl alcohol at -78℃; for 0.5h; Yield given. Title compound not separated from byproducts;
L-tert-Leucine
20859-02-3

L-tert-Leucine

benzyl chloroformate
501-53-1

benzyl chloroformate

(S)-N-carbobenzoxy-tert-butylleucine
62965-10-0

(S)-N-carbobenzoxy-tert-butylleucine

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane at 0℃; for 18h;100%
With sodium hydroxide In water for 3h; Inert atmosphere;100%
With sodium hydroxide In water at 5 - 20℃; for 14h; pH=10 - 10.5; Product distribution / selectivity;97%
methanol
67-56-1

methanol

L-tert-Leucine
20859-02-3

L-tert-Leucine

L-tert-leucine methyl ester hydrochloride
63038-27-7

L-tert-leucine methyl ester hydrochloride

Conditions
ConditionsYield
With thionyl chloride at 0 - 20℃;100%
With thionyl chloride for 16h; Reflux;100%
With hydrogenchloride Ambient temperature;98%
L-tert-Leucine
20859-02-3

L-tert-Leucine

(S)-tert-leucinol
112245-13-3

(S)-tert-leucinol

Conditions
ConditionsYield
With sodium tetrahydroborate; iodine In tetrahydrofuran for 24h; Heating;100%
Stage #1: L-tert-Leucine With iodine In tetrahydrofuran for 24h; Reflux;
Stage #2: With methanol
Stage #3: With potassium hydroxide In water
100%
With sodium tetrahydroborate; iodine In tetrahydrofuran at 0 - 80℃; for 22h; Inert atmosphere;100%
L-tert-Leucine
20859-02-3

L-tert-Leucine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N-tert-butyloxycarbonyl-L-tert-leucine
62965-35-9

N-tert-butyloxycarbonyl-L-tert-leucine

Conditions
ConditionsYield
With triethylamine In methanol at 0 - 5℃;100%
With triethylamine In methanol at 0 - 5℃;100%
With sodium hydroxide In 1,4-dioxane at 20℃; for 12h;100%
L-tert-Leucine
20859-02-3

L-tert-Leucine

methyl chloroformate
79-22-1

methyl chloroformate

(S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid
162537-11-3

(S)-2-(methoxycarbonylamino)-3,3-dimethylbutanoic acid

Conditions
ConditionsYield
With sodium hydroxide In 1,4-dioxane; water at 60℃; for 18h; pH=8 - 9;100%
With sodium hydroxide In 1,4-dioxane; water at 25 - 60℃; for 22h;98%
Stage #1: L-tert-Leucine; methyl chloroformate With sodium hydroxide In 1,4-dioxane; water at 25 - 60℃; for 22h;
Stage #2: With hydrogenchloride In water
98%
N-(Benzyloxycarbonyloxy)succinimide
13139-17-8

N-(Benzyloxycarbonyloxy)succinimide

L-tert-Leucine
20859-02-3

L-tert-Leucine

(S)-N-carbobenzoxy-tert-butylleucine
62965-10-0

(S)-N-carbobenzoxy-tert-butylleucine

Conditions
ConditionsYield
With triethylamine In methanol at 20℃; for 14h;100%
L-tert-Leucine
20859-02-3

L-tert-Leucine

3-Phenylpropionic acid
501-52-0

3-Phenylpropionic acid

N-(3-phenylpropanoyl)-L-tert-Leu-OH
205494-44-6

N-(3-phenylpropanoyl)-L-tert-Leu-OH

Conditions
ConditionsYield
Stage #1: 3-Phenylpropionic acid With chloroformic acid ethyl ester; triethylamine In tetrahydrofuran at 0℃; for 0.5h; Green chemistry;
Stage #2: L-tert-Leucine With water In tetrahydrofuran at 0℃; for 0.5h; Green chemistry;
100%
NaHSO4·H2O

NaHSO4·H2O

L-tert-Leucine
20859-02-3

L-tert-Leucine

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

N-tert-butyloxycarbonyl-L-tert-leucine
62965-35-9

N-tert-butyloxycarbonyl-L-tert-leucine

Conditions
ConditionsYield
With triethylamine In 1,4-dioxane; water99%
With triethylamine In 1,4-dioxane; water99%
L-tert-Leucine
20859-02-3

L-tert-Leucine

4-benzyloxy-3,5,6-trifluorophthalic anhydride

4-benzyloxy-3,5,6-trifluorophthalic anhydride

N-4-benzyloxy-3,5,6-trifluorophthaloyl-(S)-tert-leucine

N-4-benzyloxy-3,5,6-trifluorophthaloyl-(S)-tert-leucine

Conditions
ConditionsYield
With triethylamine In toluene for 1.25h; Reflux;99%
L-tert-Leucine
20859-02-3

L-tert-Leucine

4-phenylnaphtho[2,3-c]furan-1,3-dione
1985-37-1

4-phenylnaphtho[2,3-c]furan-1,3-dione

(S)-N-(1-phenylnaphthalene-2,3-dicarboximido)-tert-leucine

(S)-N-(1-phenylnaphthalene-2,3-dicarboximido)-tert-leucine

Conditions
ConditionsYield
With triethylamine In toluene for 12h; Inert atmosphere; Reflux;99%
In N,N-dimethyl-formamide Inert atmosphere; Reflux;89%
L-tert-Leucine
20859-02-3

L-tert-Leucine

3-(tert-butyl)-5-nitrosalicylaldehyde
72607-35-3

3-(tert-butyl)-5-nitrosalicylaldehyde

vanadium(V) oxytriethoxide
1686-22-2

vanadium(V) oxytriethoxide

C18H25N2O7V

C18H25N2O7V

Conditions
ConditionsYield
In methanol; dichloromethane for 3h; Inert atmosphere;99%
L-tert-Leucine
20859-02-3

L-tert-Leucine

3-(tert-butyl)-5-nitrosalicylaldehyde
72607-35-3

3-(tert-butyl)-5-nitrosalicylaldehyde

vanadium(V) oxytriisopropoxide
5588-84-1

vanadium(V) oxytriisopropoxide

C20H29N2O7V

C20H29N2O7V

Conditions
ConditionsYield
In methanol; dichloromethane for 3h; Inert atmosphere;99%
Stage #1: L-tert-Leucine; 3-(tert-butyl)-5-nitrosalicylaldehyde In methanol; dichloromethane for 3h; Reflux; Inert atmosphere;
Stage #2: vanadium(V) oxytriisopropoxide In dichloromethane for 3h; Inert atmosphere;
99%
L-tert-Leucine
20859-02-3

L-tert-Leucine

3-(tert-butyl)-5-nitrosalicylaldehyde
72607-35-3

3-(tert-butyl)-5-nitrosalicylaldehyde

oxovanadium(V) trimethoxide
7681-91-6

oxovanadium(V) trimethoxide

C18H25N2O7V

C18H25N2O7V

Conditions
ConditionsYield
Stage #1: L-tert-Leucine; 3-(tert-butyl)-5-nitrosalicylaldehyde In methanol; dichloromethane Reflux; Inert atmosphere;
Stage #2: oxovanadium(V) trimethoxide In methanol; dichloromethane for 3h; Inert atmosphere;
99%
1H-Indole-7-carboxylic acid
1670-83-3

1H-Indole-7-carboxylic acid

L-tert-Leucine
20859-02-3

L-tert-Leucine

C15H18N2O3

C15H18N2O3

Conditions
ConditionsYield
With coronafacic acid ligase SsCfaL for 20h; Catalytic behavior; Reagent/catalyst; Enzymatic reaction;99%
L-tert-Leucine
20859-02-3

L-tert-Leucine

Tert-butyl isocyanate
1609-86-5

Tert-butyl isocyanate

(S)-2-(3-(tert-butyl)ureido)-3,3-dimethylbutanoic acid
101968-85-8

(S)-2-(3-(tert-butyl)ureido)-3,3-dimethylbutanoic acid

Conditions
ConditionsYield
Stage #1: L-tert-Leucine With sodium hydroxide In water pH=11.5;
Stage #2: Tert-butyl isocyanate In water pH=9.3; Cooling with ice;
98%
L-tert-Leucine
20859-02-3

L-tert-Leucine

meso-endo-tetrahydro-4,7-ethanoisobenzofuran-1,3-dione
24327-08-0

meso-endo-tetrahydro-4,7-ethanoisobenzofuran-1,3-dione

(S)-N-(endo-bicyclo[2.2.2]oct-5-ene-2,3-dicarboximido)-tert-leucine

(S)-N-(endo-bicyclo[2.2.2]oct-5-ene-2,3-dicarboximido)-tert-leucine

Conditions
ConditionsYield
With triethylamine In toluene for 12h; Inert atmosphere; Reflux;98%
L-tert-Leucine
20859-02-3

L-tert-Leucine

salicylaldehyde
90-02-8

salicylaldehyde

phenylboronic acid
98-80-6

phenylboronic acid

(3S,11S)-3-(tert-butyl)-11-phenyl-11H-4l4,11l4-benzo[e][1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborinin-2(3H)-one

(3S,11S)-3-(tert-butyl)-11-phenyl-11H-4l4,11l4-benzo[e][1,3,2]oxazaborolo[2,3-b][1,3,2]oxazaborinin-2(3H)-one

Conditions
ConditionsYield
Stage #1: L-tert-Leucine; salicylaldehyde In water at 90℃; for 1h;
Stage #2: phenylboronic acid In water at 90℃; for 20h;
97%
L-tert-Leucine
20859-02-3

L-tert-Leucine

(fluorenylmethoxy)carbonyl chloride
28920-43-6

(fluorenylmethoxy)carbonyl chloride

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid
132684-60-7

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid

Conditions
ConditionsYield
With sodium carbonate In 1,4-dioxane at 0 - 20℃;96%
With sodium carbonate In 1,4-dioxane; water at 0 - 20℃; Inert atmosphere;
With sodium carbonate In 1,4-dioxane; water at 0 - 20℃; for 1h; Inert atmosphere;
With sodium carbonate In 1,4-dioxane at 0℃; for 2h;
4-tert-butylphthalic anhydride
32703-79-0

4-tert-butylphthalic anhydride

L-tert-Leucine
20859-02-3

L-tert-Leucine

(S)-N-(4-tert-butylphthalimido)-tert-leucine

(S)-N-(4-tert-butylphthalimido)-tert-leucine

Conditions
ConditionsYield
With triethylamine In toluene for 12h; Inert atmosphere; Reflux;96%
With triethylamine In toluene for 12h; Inert atmosphere; Reflux;96%
L-tert-Leucine
20859-02-3

L-tert-Leucine

3-(tert-butyl)-5-nitrosalicylaldehyde
72607-35-3

3-(tert-butyl)-5-nitrosalicylaldehyde

vanadium(V) oxytriethoxide
1686-22-2

vanadium(V) oxytriethoxide

C19H27N2O7V

C19H27N2O7V

Conditions
ConditionsYield
Stage #1: L-tert-Leucine; 3-(tert-butyl)-5-nitrosalicylaldehyde In ethanol; dichloromethane Inert atmosphere; Reflux;
Stage #2: vanadium(V) oxytriethoxide In ethanol; dichloromethane at 20℃; for 3h; Inert atmosphere;
96%
L-tert-Leucine
20859-02-3

L-tert-Leucine

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide
82911-69-1

N-(9H-fluoren-2-ylmethoxycarbonyloxy)succinimide

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid
132684-60-7

(S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,3-dimethylbutanoic acid

Conditions
ConditionsYield
With sodium carbonate In water; acetone95%
L-tert-Leucine
20859-02-3

L-tert-Leucine

C15H23ClIrO2

C15H23ClIrO2

C16H27ClIrNO2

C16H27ClIrNO2

Conditions
ConditionsYield
In methanol for 24h;95%
cobalt(II) nitrate hexahydrate

cobalt(II) nitrate hexahydrate

L-tert-Leucine
20859-02-3

L-tert-Leucine

sodium carbonate
497-19-8

sodium carbonate

3,5-di-tert-amyl-2-hydroxy-benzaldehyde
41715-33-7

3,5-di-tert-amyl-2-hydroxy-benzaldehyde

sodium Λ-bis[N-(3,5-di-tert-amyl-salicylidene)-(S)-tert-leucinato]cobaltate

sodium Λ-bis[N-(3,5-di-tert-amyl-salicylidene)-(S)-tert-leucinato]cobaltate

Conditions
ConditionsYield
Stage #1: L-tert-Leucine; sodium carbonate; 3,5-di-tert-amyl-2-hydroxy-benzaldehyde In ethanol at 90℃; for 6h;
Stage #2: cobalt(II) nitrate hexahydrate In ethanol at 90℃; for 42h;
95%
phthalic anhydride
85-44-9

phthalic anhydride

L-tert-Leucine
20859-02-3

L-tert-Leucine

(S)-(-)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3,3-dimethyl-butyric acid
142765-23-9

(S)-(-)-2-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-3,3-dimethyl-butyric acid

Conditions
ConditionsYield
With triethylamine In toluene for 2h; Heating;94%
With triethylamine In toluene for 0.5h; Heating;86%
With triethylamine In toluene at 130℃; Dean-Stark;67%
L-tert-Leucine
20859-02-3

L-tert-Leucine

cyclopentyl chloroformate
50715-28-1

cyclopentyl chloroformate

N-[(cyclopentyloxy)carbonyl]-L-tert-leucine
572924-00-6

N-[(cyclopentyloxy)carbonyl]-L-tert-leucine

Conditions
ConditionsYield
Stage #1: L-tert-Leucine With trimethylsilyl cyanide In acetonitrile for 0.25h;
Stage #2: cyclopentyl chloroformate In acetonitrile at 80℃;
94%
Stage #1: L-tert-Leucine With trimethylsilyl cyanide In acetonitrile at 75℃; for 0.75h;
Stage #2: cyclopentyl chloroformate In acetonitrile at 80℃;
94%
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