28781-92-2

Basic information

• Product Name: tetramethyl propane-1,1,3,3-tetracarboxylate
• Synonyms: 1,1,3,3-propanetetracarboxylic acid, tetramethyl ester; Tetramethyl propane-1,1,3,3-tetracarboxylate
• CAS NO: 28781-92-2
• Molecular Formula: C₁₁H₁₆O₈
• Molecular Weight: 276.2399
• Mol File: 28781-92-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 294.9°C at 760 mmHg
• Flash Point: 123.7°C
• Density: 1.228g/cm³
• Vapor Pressure: 0.00157mmHg at 25°C
• Refractive Index: 1.446
• CAS DataBase Reference: tetramethyl propane-1,1,3,3-tetracarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tetramethyl propane-1,1,3,3-tetracarboxylate(28781-92-2)
• EPA Substance Registry System: tetramethyl propane-1,1,3,3-tetracarboxylate(28781-92-2)

Safety Data

• Hazardous Substances Data: 28781-92-2(Hazardous Substances Data)

Upstream product

• 60-29-7 diethyl ether 
• 2373-51-5 chloro-methylsulfanyl-methane 
• 108-59-8 malonic acid dimethyl ester 
• 72399-18-9 formaldehyde O-benzyloxime 

Downstream Products

• 6221-56-3 1,5-Dihydroxy-2,4-di(hydroxymethyl)pentane 
• 10550-79-5 1,1,3,3-tetra(aminocarbonyl)propane 
• 27899-21-4 2,4-diethylglutaric acid 
• 27899-21-4 2,4-diethylglutaric acid 
• 1020061-56-6 2,4-bis-benzyloxymethyl-2,4-diethyl-pentanedial 
• 903502-61-4 bis(5-ethyl-3-phenyl-1,3-dioxan-5-yl)methane 
• 903502-62-5 2,4-bis(benzyloxymethyl)-2,4-diethylpentane-1,5-diol 
• 59009-71-1 N,N'-dibenzyl-3,7-diazabicyclo[3.3.1]nonane 
• 1415208-73-9 1,1,3,3-Tetra(salicylideneiminomethyl)propane 

Relevant articles and documents

Efficient multicomponent reaction for the synthesis of piperidine derivatives: Yb(OTf)3/AgOTf cocatalyzed preparation of trimethyl 3,5,5-piperidonetricarboxylate

A novel and convenient one-pot synthesis of trimethyl 3,5,5- piperidonetricarboxylate was reported. Cocatalyzed by Yb(OTf)3 and AgOTf under mild conditions, a piperidone containing a β-amino acid template was synthesized from dimethyl malonate and formaldehyde O-benzyl oxime in high yield. It could be a useful building block for the synthesis of multisubstituted piperidine derivatives. Copyright Taylor & Francis Group, LLC.