290333-11-8

Basic information

• Product Name: 4-benzyloxy-7-bromoindole
• Synonyms: 4-benzyloxy-7-bromoindole
• CAS NO: 290333-11-8
• Molecular Weight: 302.17
• Mol File: 290333-11-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-benzyloxy-7-bromoindole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-benzyloxy-7-bromoindole(290333-11-8)
• EPA Substance Registry System: 4-benzyloxy-7-bromoindole(290333-11-8)

Safety Data

• Hazardous Substances Data: 290333-11-8(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 4514-28-7 2-Bromo-5-benzyloxy-nitrobenzene 
• 1826-67-1 vinyl magnesium bromide 
• 5344-78-5 4-bromo-3-nitroanizole 
• 1761-61-1 5-bromosalicyclaldehyde 
• 121124-94-5 2-benzyloxy-5-bromobenzaldehyde 
• 290333-15-2 4-benzyloxy-7-bromoindole-2-carboxylic acid 
• 290333-13-0 ethyl 2-azido-3-(2-benzyloxy-5-bromophenyl)propenoate 
• 290333-14-1 ethyl 4-(benzyloxy)-7-bromo-1H-indole-2-carboxylate 

Downstream Products

• 290333-16-3 4-benzyloxy-7-bromo-3-[(2-amino)pyrimidin-4-yl]indole 
• 290333-08-3 N-tosyl-3-acetyl-4-benzyloxy-7-bromoindole 
• 341998-52-5 1-[4-benzyloxy-7-bromo-1-(toluene-4-sulfonyl)-1H-indol-3-yl]-3-dimethylamino-propenone 
• 1313530-04-9 C₁₈H₁₇NO₃ 
• 1313530-07-2 C₁₉H₁₆N₂O₃ 
• 290333-12-9 3-acetyl-4-benzyloxy-7-bromoindole 

Relevant articles and documents

Rapid synthesis of diversely functionalized 3,4,7-trisubstituted indoles

Synthetic approaches are described for the synthesis of 4-alkoxyindole-7-carboxamides and 4-alkoxy-3-cyanoindole-7-carboxamides, which are useful intermediates in medicinal chemistry research. Two strategies were employed, highlighted by a Bartoli indole synthesis or a sequential and regioselective use of chlorosulfonyl isocyanate to install both the 3-cyano and 7-carboxamido groups. These routes are scalable and afford diversely functionalized indoles for further elaboration.

Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin

A nine-step synthesis of 9-amino-4-methoxypyrido[3',2':4,5]pyrrolo[1,2- c]pyrimidine, a tricyclic ring system present in the marine alkaloids variolins is described. The natural marine products meridianins C-E have been synthesized for the first time starting from N-protected 3-acylindoles. (C) 2000 Elsevier Science Ltd.