290333-14-1Relevant articles and documents
Cyclization of free radicals at the C-7 position of ethyl indole-2-carboxylate derivatives: An entry to a new class of duocarmycin analogues
Al-Said, Naim H.,Shawakfeh, Khaled Q.,Abdullah, Wasim N.
, p. 1446 - 1457 (2007/10/03)
Aryl free-radicals generated at the C-7 position of ethyl indole-2-carboxylates bearing N-allyl and propargylic groups triggered intramolecular cyclizations to furnish a new class of Duocarmycin analogues, formal ethyl pyrrolo[3,2,1-ij]quinoline-2-carboxylate derivatives, through the less favorable 6-endo-trig cyclization mode.
Synthetic studies towards the 2-aminopyrimidine alkaloids variolins and meridianins from marine origin
Fresneda, Pilar M.,Molina, Pedro,Delgado, Santiago,Bleda, Juan A.
, p. 4777 - 4780 (2007/10/03)
A nine-step synthesis of 9-amino-4-methoxypyrido[3',2':4,5]pyrrolo[1,2- c]pyrimidine, a tricyclic ring system present in the marine alkaloids variolins is described. The natural marine products meridianins C-E have been synthesized for the first time starting from N-protected 3-acylindoles. (C) 2000 Elsevier Science Ltd.