29268-75-5

Basic information

• Product Name: 3,3-Dichloro-1-phenyl-1-propene
• Synonyms: 3,3-Dichloro-1-phenyl-1-propene
• CAS NO: 29268-75-5
• Molecular Weight: 187.069
• Mol File: 29268-75-5.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: 3,3-Dichloro-1-phenyl-1-propene(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-Dichloro-1-phenyl-1-propene(29268-75-5)
• EPA Substance Registry System: 3,3-Dichloro-1-phenyl-1-propene(29268-75-5)

Safety Data

• Hazardous Substances Data: 29268-75-5(Hazardous Substances Data)

Upstream product

• 104-55-2 3-phenyl-propenal 
• 14371-10-9 (E)-3-phenylpropenal 
• 7719-09-7 thionyl chloride 
• 99441-44-8 3-phenyl-2-propenyl tetrahydro-2H-pyran-2-yl ether 
• 109283-53-6 trimethylsilyl cinnamyl ether 
• 104-54-1 3-Phenylpropenol 
• 79-37-8 oxalyl dichloride 

Downstream Products

• 6052-63-7 2-phenylbut-3-en-1-ol 
• 14371-10-9 (E)-3-phenylpropenal 
• 1720-32-7 1,6-diphenyl-hexa-1,3,5-triene 
• 92-94-4 [1,1';4',1'']terphenyl 
• 1363720-60-8 (+)-(3S,4Z)-undec-4-en-3-ylbenzene 
• 1363720-61-9 (+)-(3S,4Z,6E)-trideca-4,6-dien-3-ylbenzene 
• 1363720-62-0 (+)-1-methyl-4-((3S,1Z)-3-phenylpent-1-en-1-yl)benzene 
• 1363720-54-0 (+)-(3S)-(Z)-1-chloro-5-methylhex-1-en-3-ylbenzene 
• 1363720-51-7 (+)-(3S)-(Z)-1-chloronon-1-en-3-ylbenzene 
• 1363720-52-8 (+)-(3S)-(Z)-1-chlorobut-1-en-3-ylbenzene 
• 1363720-53-9 (+)-(3S)-(Z)-1-chlorodeca-1,9-dien-3-ylbenzene 
• 1363720-50-6 (+)-(3S)-(Z)-1-chloropent-1-en-3-ylbenzene 
• 916851-87-1 cinnamaldehyde semicarbazone 
• 79-43-6 dichloro-acetic acid 

Relevant articles and documents

One-pot, oxidative and selective conversion of benzylic silyl and tetrahydropyranyl ethers to gem-dichlorides using trichloroisocyanuric acid and triphenylphosphine as an efficient and neutral system

A one-pot and oxidative method is described for the first time for the conversion of benzylic trimethylsilyl (TMS) and tetrahydropyranyl (THP) ethers to gem-dichlorides using trichloroisocyanuric acid (TCCA) and triphenylphosphine (PPh3) in neutral media. Various theses substrates containing electron withdrawing or donating groups can be efficiently converted to their corresponding gem-dichlorides in good to excellent yields. The present method shows a high degree of chemoselectivity, and due to its one-pot nature is in accordance with green chemistry.

One-pot, selective and mild conversion of benzylic alcohols to gem -dichlorides using chlorodiphenylphosphine and 2,3-dichloro-5,6-dicyanobenzoquinone as a new and neutral system

A mild and one-pot conversion of benzylic alcohols to their corresponding gem-dichlorides is reported for the first time using chlorodiphenylphosphine (ClPPh2) and 2,3-dichloro-5,6-dicyanobenzoquinone (DDQ) in dichloromethane under neutral conditions and at room temperature. The present method can be efficiently used for preparation of gem-dichlorides even in the presence of some other functional groups with excellent chemoselectivity.

Z-selective copper-catalyzed asymmetric allylic alkylation with grignard reagents

Allylic gem-dichlorides undergo regio- and enanantioselective (er up to 99:1) copper-catalyzed allylic alkylation with Grignard reagents affording chiral Z-vinyl chlorides. This highly versatile class of synthons can be subjected to Suzuki cross coupling affording optically active Z-alkenes and 1,3-cis,trans dienes.