29538-99-6

Basic information

• Product Name: 1H-2-Benzopyran-1-one, 3-(phenylmethyl)-
• CAS NO: 29538-99-6
• Molecular Formula: C16H12O2
• Molecular Weight: 236.27
• Mol File: 29538-99-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1H-2-Benzopyran-1-one, 3-(phenylmethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-2-Benzopyran-1-one, 3-(phenylmethyl)-(29538-99-6)
• EPA Substance Registry System: 1H-2-Benzopyran-1-one, 3-(phenylmethyl)-(29538-99-6)

Safety Data

• Hazardous Substances Data: 29538-99-6(Hazardous Substances Data)

Upstream product

• 89-51-0 Homophthalic acid 
• 103-80-0 phenylacetyl chloride 
• 67396-36-5 (3-bromoprop-2-yn-1-yl)benzene 
• 65-85-0 benzoic acid 
• 103-82-2 phenylacetic acid 
• 83-33-0 inden-1-one 
• 100-52-7 benzaldehyde 
• 93433-54-6 2-benzylindan-1-ol 
• 16274-93-4 2-benzyl-1H-indene 
• 16307-30-5 2-benzyl-1-indanone 
• 5706-12-7 (E)-2-benzylidene-2,3-dihydro-1H-inden-1-one 
• 831171-86-9 2-(2-oxo-3-phenylpropyl)benzaldehyde 
• 221056-41-3 2-(2-oxo-3-phenylpropyl)benzoic acid methyl ester 
• 67-56-1 methanol 

Downstream Products

• 29539-12-6 3-Benzyl-3-hydroxy-isochroman 
• 29539-17-1 2-(2'-Hydroxy-3'-phenyl-propyl)-benzylalkohol 
• 29539-16-0 2-(2'-Oxo-3'-phenylpropyl)-benzylbromid 
• 221056-41-3 2-(2-oxo-3-phenylpropyl)benzoic acid methyl ester 
• 56595-88-1 (dl)-3-benzyl-3,4-dihydroisocoumarin 
• 2852-89-3 2-(2'-oxo-3'-phenylpropyl)benzoic acid 

Relevant articles and documents

Palladium-Catalyzed Sequential Nucleophilic Addition/Oxidative Annulation of Bromoalkynes with Benzoic Acids to Construct Functionalized Isocoumarins

An efficient and robust protocol for the preparation of 3-substituted isocoumarins via palladium-catalyzed nucleophilic addition/oxidative annulation of bromoalkynes with benzoic acids has been developed. Remarkably, preliminary mechanistic studies indicated that the transformation might proceed via a stereo- and regioselective nucleophilic addition and C-H functionalization procedure.

Studies on the chemistry of 2-(2-oxo-3-phenylpropyl)-benzaldehydes: Novel total synthesis of 3-phenylnaphthalen-2-ols and 2-hydroxy-3-phenyl-1,4- naphthoquinones

We describe the first studies on the chemistry of 2-(2-oxo-3-phenylpropyl) benzaldehydes, which were converted into 3-benzylisochromen-1-ones via the corresponding 2-(2-oxo-3-phenylpropyl)benzoic acid. The 2-(2-oxo-3-phenylpropyl) benzaldehydes proved to be convenient starting materials for the synthesis of 3-phenyl-2-naphthols. Oxidation of the latter compounds resulted in a novel, efficient synthesis of 3-phenyl-1,2-naphthoquinones, which were efficiently transformed into 2-hydroxy-3-phenyl-1,4-naphthoquinones.

Preparation of 2-(oxoalkyl)-benzyl bromides

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