29555-02-0 Usage
Description
2-METHYLCYCLOPROPANECARBOXYLIC ACID, also known as cis-2-methylcyclopropanecarboxylic acid, is an organic compound with the chemical formula C5H8O2. It is a clear, colorless to light yellow liquid and is a component of curacin A, a natural product with potential biological activities.
Uses
Used in Pharmaceutical Industry:
2-METHYLCYCLOPROPANECARBOXYLIC ACID is used as a chemical intermediate for the preparation of Spirocyclic Dihydroindols, which are HPK1 inhibitors. These inhibitors play a crucial role in the development of novel therapeutic strategies for various diseases, including cancer and autoimmune disorders, by modulating the activity of the hematopoietic progenitor kinase 1 (HPK1).
Used in Natural Product Synthesis:
In the field of natural product synthesis, 2-METHYLCYCLOPROPANECARBOXYLIC ACID serves as a key component in the synthesis of curacin A, a complex natural product with potential applications in drug discovery and development. Curacin A has been studied for its cytotoxic and antimitotic properties, making it a valuable compound for further research and potential therapeutic applications.
Check Digit Verification of cas no
The CAS Registry Mumber 29555-02-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,9,5,5 and 5 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 29555-02:
(7*2)+(6*9)+(5*5)+(4*5)+(3*5)+(2*0)+(1*2)=130
130 % 10 = 0
So 29555-02-0 is a valid CAS Registry Number.
InChI:InChI=1/C5H8O2/c1-3-2-4(3)5(6)7/h3-4H,2H2,1H3,(H,6,7)/p-1/t3-,4-/m1/s1
29555-02-0Relevant articles and documents
SUBSTITUTED CARBOXAMIDES
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Page/Page column 19, (2008/12/08)
This application relates to a substituted carboxamide compound of formula I, or a pharmaceutically acceptable salt thereof, as defined herein, a pharmaceutical composition thereof, and its use in treating pain.
Cyanovinyl cyclopropanecarboxylic acids
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, (2008/06/13)
The invention relates to novel substituted cyanovinyl cyclopropanecarboxylic acids and method of preparation thereof. The cyanovinyl cyclopropanecarboxylic acids are useful intermediates for the preparation of novel insecticidal-acaricidal pyrethroids.
