295790-58-8

Basic information

• Product Name: 2-chloro-4-fluoro-N-(2-chloroethyl)-N-methylbenzene sulfonamide
• CAS NO: 295790-58-8
• Molecular Weight: 286.154
• Mol File: 295790-58-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-chloro-4-fluoro-N-(2-chloroethyl)-N-methylbenzene sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-chloro-4-fluoro-N-(2-chloroethyl)-N-methylbenzene sulfonamide(295790-58-8)
• EPA Substance Registry System: 2-chloro-4-fluoro-N-(2-chloroethyl)-N-methylbenzene sulfonamide(295790-58-8)

Safety Data

• Hazardous Substances Data: 295790-58-8(Hazardous Substances Data)

Upstream product

• 109-83-1 (2-hydroxyethyl)(methyl)amine 
• 82875-86-3 2-chloro-5-fluorobenzene sulphonyl chloride 

Downstream Products

• 295790-21-5 2-chloro-4-fluoro-N-(2-(4-(5-fluoro-1H-benzimidazol-2-yl)-piperidin-1-yl)-ethyl)-N-methyl-benzenesulfonamide 

Relevant articles and documents

Sulfonamide derivatives as 5-HT7 receptor antagonists

The invention relates to novel sulfonamide compounds having 5-HT7receptor antagonist activity, processes for their preparation, to compositions containing them and to their use in the treatment of CNS and other disorders. wherein: Q is phenyl or thienyl; R1is halogen, hydroxy, C1-6alkyl, CF3, OCF3or C1-6alkoxy; m is 0, 1, 2 or 3; R2is C1-4alkyl; X is carbon or CH, is a single bond when X is nitrogen or CH or is a double bond when X is carbon, D is a single bond, C═O, O or CH2subject to the proviso that when X is nitrogen then D is not oxygen; P is a 5 or 6 membered heteroaryl ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulphur, or a benzofused heteroaryl ring containing 1 to 3 heteroatoms selected from oxygen, nitrogen and sulphur; R3is C1-6alkyl optionally substituted by NR4R5, aryl, arylC1-6alkyl, C1 6alkoxy, C1-6alkylthio, cyano, hydroxy, nitro, halogen, CF3, C2F5, NR4R5, CONR4R5, NR4COR5, S(O)pNR4R5, CHO, OCF3, SCF3, CH2OR6, CO2R6or COR6where p is 0, 1 or 2 and R4, R5and R6are independently hydrogen, C1-6alkyl, aryl or arylC1-6alkyl; n is 0, 1, 2 or 3.