296778-52-4

Basic information

• Product Name: Carbamic acid, (2,4-dichlorophenyl)-, 1,1-dimethylethyl ester
• CAS NO: 296778-52-4
• Molecular Formula: C11H13Cl2NO2
• Molecular Weight: 262.136
• Mol File: 296778-52-4.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (2,4-dichlorophenyl)-, 1,1-dimethylethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (2,4-dichlorophenyl)-, 1,1-dimethylethyl ester(296778-52-4)
• EPA Substance Registry System: Carbamic acid, (2,4-dichlorophenyl)-, 1,1-dimethylethyl ester(296778-52-4)

Safety Data

• Hazardous Substances Data: 296778-52-4(Hazardous Substances Data)

Upstream product

• 18437-66-6 N-(t-butoxycarbonyl)-4-chloroaniline 
• 24424-99-5 di-tert-butyl dicarbonate 
• 106-47-8 4-chloro-aniline 
• 4248-19-5 tert-butyl carbazate 
• 541-73-1 1,3-Dichlorobenzene 
• 1965-25-9 1-azido-2,4-dichlorobenzene 

Downstream Products

• 554-00-7 2,4-Dichloroaniline 

Relevant articles and documents

Chlorination Reaction of Aromatic Compounds and Unsaturated Carbon-Carbon Bonds with Chlorine on Demand

Chlorination with chlorine is straightforward, highly reactive, and versatile, but it has significant limitations. In this Letter, we introduce a protocol that could combine the efficiency of electrochemical transformation and the high reactivity of chlorine. By utilizing Cl3CCN as the chloride source, donating up to all three chloride atom, the reaction could generate and consume the chlorine in situ on demand to achieve the chlorination of aromatic compounds and electrodeficient alkenes.

Highly ortho-Selective Chlorination of Anilines Using a Secondary Ammonium Salt Organocatalyst

An organocatalytic, highly facile, efficient, and regioselective ortho-chlorination of anilines is described. A secondary ammonium chloride salt has been employed as the catalyst and the reaction can be conducted at room temperature without protection from air and moisture. In addition, the reaction is readily scalable and the catalyst can be recycled and reused. This catalytic protocol has been applied to the efficient synthesis of a highly potent c-Met kinase inhibitor. Mechanistic studies revealed that unique structural features of the secondary ammonium chloride salt are important for both the catalysis and regioselectivity of the electrophilic ortho-chlorination.

Direct conversion of azides and benzyl carbamates to t-butyl carbamates using polymethylhydrosiloxane and Pd-C

One step direct conversion of azides and benzyl carbamates to t-butyl carbamales is achieved using inexpensive and safe hydride source namely polymethylhydrosiloxane (PMHS) under Pd-C catalysis.