29927-14-8

Basic information

• Product Name: 6-hydroxybenzothiazide-2-sulfonamide
• Synonyms: 6-hydroxybenzothiazide-2-sulfonamide;6-Hydroxy-2-benzothiazolesulfonamide;6-Hydroxybenzothiazole-2-sulfonamide
• CAS NO: 29927-14-8
• Molecular Formula: C₇H₆N₂O₃S₂
• Molecular Weight: 0
• Mol File: 29927-14-8.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 512.7°C at 760 mmHg
• Flash Point: 263.9°C
• Appearance: /
• Density: 1.723g/cm³
• Vapor Pressure: 3.92E-11mmHg at 25°C
• Refractive Index: 1.745
• CAS DataBase Reference: 6-hydroxybenzothiazide-2-sulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 6-hydroxybenzothiazide-2-sulfonamide(29927-14-8)
• EPA Substance Registry System: 6-hydroxybenzothiazide-2-sulfonamide(29927-14-8)

Safety Data

• Hazardous Substances Data: 29927-14-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C7H6N2O3S2/c8-14(11,12)7-9-5-3-4(10)1-2-6(5)13-7/h1-3,10H,(H2,8,11,12)

Upstream product

• 452-35-7 6-ethoxybenzothiazole-2-sulfonamide 
• 86394-94-7 2-sulfamoyl-6-benzothiazolyl 2,2-dimethylpropionate 
• 120-53-6 6-ethoxy-2-mercaptobenzothiazole 
• 5304-15-4 6-ethoxy-2-benzothiazolesulfenamide 

Downstream Products

• 86394-93-6 2-sulfamoyl-6-benzothiazolyl 2-phenylacetate 
• 121811-05-0 2,4,6-Trimethyl-benzoic acid 2-sulfamoyl-benzothiazol-6-yl ester 
• 121811-03-8 4-(2-Diethylamino-ethoxy)-benzoic acid 2-sulfamoyl-benzothiazol-6-yl ester 
• 86394-97-0 (E)-3-Phenyl-acrylic acid 2-sulfamoyl-benzothiazol-6-yl ester 
• 86395-15-5 2-sulfamoyl-6-benzothiazolyl benzoate 
• 121811-02-7 4-Dimethylaminomethyl-benzoic acid 2-sulfamoyl-benzothiazol-6-yl ester 
• 121811-01-6 4-Dimethylamino-benzoic acid 2-sulfamoyl-benzothiazol-6-yl ester 
• 93105-20-5 (2-Sulfamoyl-6-benzothiazolyl) 4-methylphenylsulfonate 
• 86394-95-8 (2-sulfamoyl-6-benzothiazolyl)2-(4-chlorophenyl) acetate 
• 121811-04-9 2,6-Dimethoxy-benzoic acid 2-sulfamoyl-benzothiazol-6-yl ester 
• 1071474-91-3 N-(bis(4-methoxyphenyl)(phenyl)methyl)-6-(prop-2-ynyloxy)benzo[d]thiazole-2-sulfonamide 
• 1071471-17-4 (R)-3-(benzylthio)-2-(2-(4-((2-sulfamoylbenzo[d]thiazol-6-yloxy)methyl)-1H-1,2,3-triazol-1-yl)acetamido)propanoic acid 

Relevant articles and documents

A class of sulfonamide carbonic anhydrase inhibitors with neuropathic pain modulating effects

A series of benzene sulfonamide carbonic anhydrase (CA, EC 4.2.1.1) inhibitors which incorporate lipophilic 4-alkoxy- and 4-aryloxy moieties, together with several derivatives of ethoxzolamide and sulfanilamide are reported. These derivatives were investi

Topically active ocular benzothiazole sulfonamide carbonic anhydrase inhibitors

This invention is directed to compounds of the formula STR1 and pharmaceutically acceptable salts thereof wherein R6 is hydrogen or lower alkyl; each R1 is hydrogen, lower alkyl, halogen, nitro, trihaloalkyl, lower alkoxy, formyl, lower alkanoyl, loweralkylamino or diloweralkylamino STR2 X is O, S or NR5 ; R2 is OR7 or NR7 R8 ; each R3 and R4 are independently hydrogen or lower alkyl; R5 R7 and R8 are independently hydrogen or lower alkyl; n is 0-3 and m is 0-6. These compounds are useful for treating glaucoma or assessing corneal function in mammals.

Benzothiazolesulfonamide derivatives for the topical treatment of elevated intraocular pressure

Novel carbonates of 6(or 5)-hydroxy-2-benzothiazolesulfonamide are useful for the topical treatment of elevated intraocular pressure. Ophthalmic compositions include drops and inserts.