300356-31-4

Basic information

• Product Name: 4-Bromo-1-(methylthio)-2-(trifluoromethyl)-benzene
• Synonyms: 4-Bromo-1-(methylthio)-2-(trifluoromethyl)-benzene;4-Bromo-2-(trifluoromethyl)thioanisole
• CAS NO: 300356-31-4
• Molecular Formula: C₈H₆BrF₃S
• Molecular Weight: 271.0974496
• Mol File: 300356-31-4.mol
• Article Data: 10

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-Bromo-1-(methylthio)-2-(trifluoromethyl)-benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Bromo-1-(methylthio)-2-(trifluoromethyl)-benzene(300356-31-4)
• EPA Substance Registry System: 4-Bromo-1-(methylthio)-2-(trifluoromethyl)-benzene(300356-31-4)

Safety Data

• Hazardous Substances Data: 300356-31-4(Hazardous Substances Data)

Upstream product

• 624-92-0 Dimethyldisulphide 
• 445-02-3 4-bromo-2-trifluoromethyl-aniline 
• 75-18-3 dimethylsulfide 
• 322-58-7 2-(methylthio)-1-(trifluoromethyl)benzene 
• 110-46-3 isopentyl nitrite 
• 393-37-3 5-bromo-2-fluorobenzotrifluoride 
• 5188-07-8 sodium thiomethoxide 

Downstream Products

• 300356-32-5 4-bromo-1-(methylsulfonyl)-2-(trifluoromethyl)benzene 
• 877383-11-4 [4-(methylthio)-3-(trifluoromethyl)phenyl]-boronic acid 
• 1006899-20-2 5,5-dimethyl-3-(4-(methylsulfonyl)-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione 

Relevant articles and documents

NOVEL IMIDAZOLIDINE-2, 4-DIONE DERIVATIVES

A subject of the present application is novel imidazolidine-2, 4-dione derivatives of general formula (I) These products have an anti-proliferative activity. They are particularly useful for treating the pathological states and the diseases linked to an abnormal cell proliferation such as cancers. The invention also relates to the pharmaceutical compositions containing said products and their use for the preparation of a medicament.

NAPHTHYLACETIC ACIDS

The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.

PHENOXIACETIC ACID DERIVATIVES

The invention relates to certain 2-substituted phenoxyacetic acid derivatives of formula (I), in which the variables are as defined in the claims, useful in the treatment of diseases or conditions in which modulation of the CRTh2 receptor is beneficial, s