300356-32-5

Basic information

• Product Name: 5-Bromo-2-(methylsulfonyl)benzotrifluoride
• Synonyms: 5-Bromo-2-(methylsulfonyl)benzotrifluoride;4-Bromo-2-(trifluoromethyl)phenyl methyl sulphone, 4-(Methylsulphonyl)-3-(trifluoromethyl)bromobenzene;5-Bromo-2-(methylsulphonyl)benzotrifluoride;1-Bromo-4-(methylsulfonyl)-3-(trifluoromethyl)benzene;4-BroMo-1-(Methylsulfonyl)-2-(trifluoroMethyl)benzene;4-Bromo-1-(methylsulfonyl)
• CAS NO: 300356-32-5
• Molecular Formula: C₈H₆BrF₃O₂S
• Molecular Weight: 303
• Mol File: 300356-32-5.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5-Bromo-2-(methylsulfonyl)benzotrifluoride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Bromo-2-(methylsulfonyl)benzotrifluoride(300356-32-5)
• EPA Substance Registry System: 5-Bromo-2-(methylsulfonyl)benzotrifluoride(300356-32-5)

Safety Data

• Hazardous Substances Data: 300356-32-5(Hazardous Substances Data)

Usage

General Description

5-Bromo-2-(methylsulfonyl)benzotrifluoride is a specialized chemical compound notable for its use in organic synthesis, often as an intermediate compound. It contains several distinctive functional groups, including a bromine atom, a methylsulfonyl group, and a trifluoride group attached to a benzene ring. This arrangement of atoms affords the compound with unique reactivity and characteristics. While its exact uses can vary depending on the nature of the synthesis, its primary function is typically to introduce the trifluoromethyl group into other chemical structures. However, information regarding its safety, toxicity, and environmental impacts are limited or unspecified, although standard safety protocols should be observed while handling and storing this chemical.

Upstream product

• 300356-31-4 (4-bromo-2-(trifluoromethyl)phenyl)(methyl)sulfane 
• 393-37-3 5-bromo-2-fluorobenzotrifluoride 

Downstream Products

• 847149-17-1 methyl {4-chloro-2-[4-(methylsulfonyl)-3-(trifluoromethyl)phenoxy]phenoxy}acetate 
• 648905-05-9 1-(2-{4-[2-(4-methanesulfonyl-3-methoxy-phenyl)-6-methoxy-naphthalen-1-yloxy]-phenoxy}-ethyl)-piperidine 
• 1006899-20-2 5,5-dimethyl-3-(4-(methylsulfonyl)-3-(trifluoromethyl)phenyl)imidazolidine-2,4-dione 

Relevant articles and documents

NOVEL IMIDAZOLIDINE-2, 4-DIONE DERIVATIVES

A subject of the present application is novel imidazolidine-2, 4-dione derivatives of general formula (I) These products have an anti-proliferative activity. They are particularly useful for treating the pathological states and the diseases linked to an abnormal cell proliferation such as cancers. The invention also relates to the pharmaceutical compositions containing said products and their use for the preparation of a medicament.

NAPHTHYLACETIC ACIDS

The invention is concerned with the compounds of formula (I) and pharmaceutically acceptable salts and esters thereof, wherein X, Q, and R1-R6 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds of formula (I) are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.

SELECTIVE ESTROGEN RECEPTOR MODULATORS CONTAINING A PHENYLSULFONYL GROUP

The present invention relates to a selective estrogen receptor modulator of formula I or a pharmaceutical acid addition salt thereof; useful, e.g., for treating endometriosis and/or uterine leiomyoma/leiomyomata.