30086-49-8Relevant articles and documents
Synthesis of quaternary carbon-centered indolo[1,2-a]quinazolinones and indazolo[1,2-a]indazolonesviaC-H functionalization
Gogoi, Kongkona,Bora, Bidisha R.,Borah, Geetika,Sarma, Bipul,Gogoi, Sanjib
supporting information, p. 1388 - 1391 (2021/02/22)
An unprecedented Ru(ii)-catalyzed Csp2-H bond activation and annulation reaction of phenylindazolones with diaryl-substituted alkynes and dialkyl-substituted alkynes provided efficient routes for the construction of all-carbon quaternary-centered indolo[1,2-a]quinazolinones and quaternary carbon-centered indazolo[1,2-a]indazolones, respectively. The indolo[1,2-a]quinazolinones were fomedviaCsp2-H activation, alkyne insertion and a 1,2-phenyl shift. Indazolo[1,2-a]indazolones were formed through a cascade reactionviathe formation of exocyclic double bonds containing indolo[1,2-a]quinazolinones.
Synthesis and anti-microbial / anti-malarial activity of a new class of chromone-dihydroquinazolinone hybrid heterocycles
Bathini, Pavan Kumar,Yerrabelly, Hemasri,Yerrabelly, Jayaprakash Rao
, p. 212 - 228 (2018/07/05)
A new series of chromone-2,3-dihydroquinazolin-4-one hybrid heterocycles are synthesized from chromone-2-carbaldehydes by coupling with 2-Aminoarylamides and hydrazides without oxidizing agents. The newly synthesized products exhibited moderate to good antimicrobial activity.
Anti-tumor pyrimidine compounds and preparation method thereof
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Paragraph 0049, (2017/08/28)
The invention belongs to the field of medicines and particularly relates to anti-tumor pyrimidine compounds and a preparation method thereof. The compounds belong to novel VEGFR (vascular endothelial growth factor receptor)-2 inhibitors and show good inhi